iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028544

Ensembl Protein ID

ENSDARP00000131420.1

UniProt Accession

A0A0G2KGI5; A0A0G2KGI5_DANRE

Genbank Protein ID

ENSDARP00000131420

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

CABZ01072560

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000015068.8	ENSDART00000157595.1	ENSDARP00000131420.1
ENSDARG00000015068.8	ENSDART00000102003.4	ENSDARP00000092779.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.60e-11	44.2	1	53

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           v ++yd++a ++ +Ltl++G++  ++  ++qd+ W+++ k+ +g +G++P+n+v++
   Q: 1    VVAMYDFTARESSDLTLHRGETYIIL--HKQDQLWWRA-KDRHGNKGFIPSNYVTE 53
           679*******************9999..9*********.7*************986 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

VVAMYDFTAR ESSDLTLHRG ETYIILHKQD QLWWRAKDRH GNKGFIPSNY VTENVSNQLE 60
QYNWYCKNIN RAEAEHLLRQ EGKDGGFVVR SSSQPSTYTV SVYTHWISSG KGEVRHYQIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGTAGCCA TGTATGACTT CACAGCCAGA GAGAGTTCAG ACCTGACGCT GCACCGCGGA 60
GAAACATACA TCATCCTCCA TAAACAAGAC CAGCTGTGGT GGAGAGCCAA AGACAGGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001365	Ailuropoda melanoleuca	57.96	1.00e-149	523.00
IUUC-Apl-003669	Anas platyrhynchos	66.92	5.00e-161	561.00
IUUC-Aca-004978	Anolis carolinensis	55.58	1.00e-139	490.00
IUUC-Ame-010694	Astyanax mexicanus	75.37	0.00e+00	648.00
IUUC-Bta-012467	Bos taurus	58.21	3.00e-150	525.00
IUUC-Cja-018841	Callithrix jacchus	58.21	7.00e-150	524.00
IUUC-Cfa-020983	Canis familiaris	58.21	4.00e-150	525.00
IUUC-Cpo-021307	Cavia porcellus	58.46	2.00e-150	526.00
IUUC-Csa-023508	Chlorocebus sabaeus	57.96	3.00e-150	525.00
IUUC-Dno-029828	Dasypus novemcinctus	58.46	1.00e-150	526.00
IUUC-Dor-030102	Dipodomys ordii	56.72	1.00e-138	486.00
IUUC-Ete-032981	Echinops telfairi	49.25	2.00e-117	416.00
IUUC-Eca-033594	Equus caballus	57.96	2.00e-149	522.00
IUUC-Eeu-035281	Erinaceus europaeus	53.07	2.00e-104	373.00
IUUC-Fca-035495	Felis catus	58.21	2.00e-150	526.00
IUUC-Fal-036771	Ficedula albicollis	66.67	4.00e-161	561.00
IUUC-Gga-041193	Gallus gallus	59.31	2.00e-148	520.00
IUUC-Gac-042383	Gasterosteus aculeatus	61.98	9.00e-144	503.00
IUUC-Hsa-045931	Homo sapiens	57.96	2.00e-149	522.00
IUUC-Itr-048061	Ictidomys tridecemlineatus	57.71	5.00e-149	521.00
IUUC-Lch-050516	Latimeria chalumnae	70.30	1.00e-168	586.00
IUUC-Loc-052730	Lepisosteus oculatus	71.64	0.00e+00	634.00
IUUC-Laf-053516	Loxodonta africana	58.21	2.00e-150	526.00
IUUC-Mcc-054795	Macaca mulatta	57.96	2.00e-149	523.00
IUUC-Meu-056157	Macropus eugenii	59.26	1.00e-141	497.00
IUUC-Mga-060196	Meleagris gallopavo	67.33	4.00e-167	581.00
IUUC-Mmr-060824	Microcebus murinus	57.96	1.00e-149	523.00
IUUC-Mdo-062054	Monodelphis domestica	68.32	6.00e-168	584.00
IUUC-Mmu-064047	Mus musculus	58.21	3.00e-150	525.00
IUUC-Mpu-066786	Mustela putorius furo	68.56	9.00e-169	587.00
IUUC-Mlu-067671	Myotis lucifugus	57.96	2.00e-142	499.00
IUUC-Nle-069108	Nomascus leucogenys	57.96	1.00e-149	523.00
IUUC-Opr-070505	Ochotona princeps	46.27	6.00e-110	391.00
IUUC-Ont-072585	Oreochromis niloticus	74.50	0.00e+00	639.00
IUUC-Oan-073495	Ornithorhynchus anatinus	58.46	2.00e-149	522.00
IUUC-Ocu-074416	Oryctolagus cuniculus	57.96	2.00e-149	523.00
IUUC-Ola-086938	Oryzias latipes	73.18	4.00e-178	617.00
IUUC-Oga-088995	Otolemur garnettii	58.21	1.00e-149	523.00
IUUC-Oar-089632	Ovis aries	58.21	2.00e-150	526.00
IUUC-Ptr-090941	Pan troglodytes	57.96	1.00e-149	523.00
IUUC-Pan-091900	Papio anubis	56.22	3.00e-141	495.00
IUUC-Psi-093565	Pelodiscus sinensis	68.81	9.00e-166	577.00
IUUC-Pfo-096955	Poecilia formosa	73.13	0.00e+00	637.00
IUUC-Pab-097587	Pongo abelii	57.96	1.00e-149	523.00
IUUC-Pva-102583	Pteropus vampyrus	57.71	6.00e-142	498.00
IUUC-Rno-104868	Rattus norvegicus	56.82	4.00e-144	504.00
IUUC-Sha-106744	Sarcophilus harrisii	57.46	6.00e-149	521.00
IUUC-Sar-113041	Sorex araneus	57.96	9.00e-149	520.00
IUUC-Ssc-115294	Sus scrofa	57.96	8.00e-150	524.00
IUUC-Tgu-116458	Taeniopygia guttata	66.92	1.00e-165	576.00
IUUC-Tsy-118945	Tarsius syrichta	57.96	6.00e-147	514.00
IUUC-Ttr-128769	Tursiops truncatus	57.66	9.00e-144	504.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence