iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074592

Ensembl Protein ID

ENSOCUP00000000461.2

UniProt Accession

G1SDH7; G1SDH7_RABIT

Genbank Protein ID

ENSOCUP00000000461

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02048297

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000000531.2	ENSOCUT00000000532.2	ENSOCUP00000000461.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-21	76.2	613	651

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 613  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 651
           8***********999*********************998 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCCCGC AGAGCCGGCA CCCGGTGAGG CGCGGCCGGG TGGGTGGGGG CAGGCGCGCG 60
GGGCTTGGGA GACTCGGTCT TGTGCAGTAG GGTGGTGGAC GGCTGTCGTA TACCCCCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001746	Ailuropoda melanoleuca	91.61	0.00e+00	1254.00
IUUC-Apl-003594	Anas platyrhynchos	90.97	0.00e+00	1236.00
IUUC-Aca-005053	Anolis carolinensis	92.96	0.00e+00	1276.00
IUUC-Bta-013380	Bos taurus	87.16	0.00e+00	1152.00
IUUC-Cja-019135	Callithrix jacchus	95.71	0.00e+00	1306.00
IUUC-Cfa-020611	Canis familiaris	95.66	0.00e+00	1189.00
IUUC-Cpo-022495	Cavia porcellus	95.19	0.00e+00	1303.00
IUUC-Csa-024056	Chlorocebus sabaeus	95.97	0.00e+00	1313.00
IUUC-Cin-025767	Ciona intestinalis	57.31	1.00e-169	590.00
IUUC-Dno-029011	Dasypus novemcinctus	95.46	0.00e+00	1301.00
IUUC-Ete-032533	Echinops telfairi	86.49	0.00e+00	1187.00
IUUC-Eca-033351	Equus caballus	95.97	0.00e+00	1309.00
IUUC-Eeu-034666	Erinaceus europaeus	94.80	0.00e+00	1072.00
IUUC-Fal-036696	Ficedula albicollis	94.41	0.00e+00	1244.00
IUUC-Gmo-038805	Gadus morhua	80.97	0.00e+00	1168.00
IUUC-Gga-041113	Gallus gallus	94.29	0.00e+00	1349.00
IUUC-Gac-041999	Gasterosteus aculeatus	80.58	0.00e+00	1172.00
IUUC-Ggo-045164	Gorilla gorilla	96.10	0.00e+00	1314.00
IUUC-Hsa-047011	Homo sapiens	96.10	0.00e+00	1314.00
IUUC-Itr-048040	Ictidomys tridecemlineatus	90.89	0.00e+00	1263.00
IUUC-Lch-050437	Latimeria chalumnae	90.53	0.00e+00	1120.00
IUUC-Loc-052819	Lepisosteus oculatus	88.35	0.00e+00	1231.00
IUUC-Laf-053862	Loxodonta africana	92.69	0.00e+00	1263.00
IUUC-Mcc-055735	Macaca mulatta	92.04	0.00e+00	1296.00
IUUC-Mmr-061207	Microcebus murinus	92.31	0.00e+00	1258.00
IUUC-Mdo-062493	Monodelphis domestica	95.06	0.00e+00	1353.00
IUUC-Mmu-063795	Mus musculus	91.18	0.00e+00	1258.00
IUUC-Mpu-065819	Mustela putorius furo	95.46	0.00e+00	1333.00
IUUC-Mlu-067047	Myotis lucifugus	95.58	0.00e+00	1290.00
IUUC-Nle-069684	Nomascus leucogenys	95.84	0.00e+00	1305.00
IUUC-Opr-071172	Ochotona princeps	95.06	0.00e+00	1286.00
IUUC-Ont-072102	Oreochromis niloticus	81.05	0.00e+00	1185.00
IUUC-Ola-087267	Oryzias latipes	78.81	0.00e+00	1096.00
IUUC-Oga-088629	Otolemur garnettii	92.82	0.00e+00	1264.00
IUUC-Oar-089551	Ovis aries	94.55	0.00e+00	1286.00
IUUC-Ptr-091207	Pan troglodytes	95.71	0.00e+00	1308.00
IUUC-Pan-091822	Papio anubis	92.04	0.00e+00	1296.00
IUUC-Psi-093594	Pelodiscus sinensis	91.47	0.00e+00	1270.00
IUUC-Pma-094452	Petromyzon marinus	76.34	0.00e+00	1093.00
IUUC-Pfo-096239	Poecilia formosa	80.13	0.00e+00	1176.00
IUUC-Pab-097687	Pongo abelii	96.06	0.00e+00	1296.00
IUUC-Pca-100675	Procavia capensis	94.23	0.00e+00	1050.00
IUUC-Pva-102355	Pteropus vampyrus	91.55	0.00e+00	1193.00
IUUC-Rno-106027	Rattus norvegicus	94.17	0.00e+00	1303.00
IUUC-Sha-107419	Sarcophilus harrisii	90.14	0.00e+00	1271.00
IUUC-Sar-113585	Sorex araneus	86.75	0.00e+00	716.00
IUUC-Ssc-116151	Sus scrofa	95.45	0.00e+00	1302.00
IUUC-Tgu-117387	Taeniopygia guttata	94.42	0.00e+00	1321.00
IUUC-Tru-118051	Takifugu rubripes	76.97	0.00e+00	1124.00
IUUC-Tsy-119342	Tarsius syrichta	88.01	0.00e+00	1017.00
IUUC-Tbe-127881	Tupaia belangeri	95.45	0.00e+00	1286.00
IUUC-Xtr-131792	Xenopus tropicalis	85.57	0.00e+00	1229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence