iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017111

Ensembl Protein ID

Bra001468.1-P

UniProt Accession

M4CB88; M4CB88_BRARP

Protein Name

Defective in cullin neddylation protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra001468	Bra001468.1	Bra001468.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.50e-86	290.3	55	241
UBD/Alpha-Helix/UBA	6.50e-06	27.1	8	46

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkdi 97
           ++++leel++rYkd+++d+i+++g++ +c dl+v+p+di++Lvl+w+++aat+cefsreef+ gl+alg+dsi+klqekl +++selkdeqkf++i
   Q: 55   DVRRLEELYNRYKDQYSDMILADGISVLCTDLQVEPQDIVTLVLSWHMNAATACEFSREEFVGGLQALGVDSIKKLQEKLSFMRSELKDEQKFHEI 150
           689********************************************************************************************* PP
   S: 98   YrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
           Y+faf +ak+kgqksl+ldtai +w+Ll+aere++l+++w++fL+++++k+iskDtW++lLef++++++ lsnYd+egaWP+liDefveyl
   Q: 151  YNFAFGWAKEKGQKSLALDTAIGMWQLLFAEREWPLVNHWCDFLQDRHNKAISKDTWEQLLEFARTVDPSLSNYDAEGAWPYLIDEFVEYL 241
           *****************************************************************************************97 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlve.MGFdreealqaLraannnleaAveyLld 40
           + dk++q+v+ +G +++ alq L a++++leaA + +++
   Q: 8    NRDKVQQFVAiTGASEKNALQTLKASDWQLEAAFDVFYS 46
           569******************************999886 PP

Organism

Brassica rapa

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MHKLSRSNRD KVQQFVAITG ASEKNALQTL KASDWQLEAA FDVFYSQPQP RSNADVRRLE 60
ELYNRYKDQY SDMILADGIS VLCTDLQVEP QDIVTLVLSW HMNAATACEF SREEFVGGLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAAGCG CTTTCTCCTC CATCTACCTT TTTTGATAAG CTTTGTTCAT GCCTTTTGCT 60
TTTAGGGTTT TTGATAATTC GAAGAGAAAC ACTCTAAAGT CCCTTACTTT GATTCAATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	69.48	1.00e-105	375.00
IUUC-Aml-001879	Ailuropoda melanoleuca	43.50	4.00e-57	214.00
IUUC-Atr-002697	Amborella trichopoda	81.82	9.00e-53	197.00
IUUC-Apl-003933	Anas platyrhynchos	44.72	4.00e-58	217.00
IUUC-Aca-005269	Anolis carolinensis	44.13	4.00e-57	214.00
IUUC-Ath-007531	Arabidopsis thaliana	92.00	1.00e-136	478.00
IUUC-Ago-007806	Ashbya gossypii	25.41	4.00e-17	81.30
IUUC-Acl-008172	Aspergillus clavatus	26.69	1.00e-24	106.00
IUUC-Afl-008569	Aspergillus flavus	29.46	2.00e-30	125.00
IUUC-Afu-009005	Aspergillus fumigatus	28.49	1.00e-19	89.00
IUUC-Ani-009241	Aspergillus nidulans	24.08	4.00e-22	98.20
IUUC-Ang-009664	Aspergillus niger	28.63	1.00e-25	109.00
IUUC-Aor-009902	Aspergillus oryzae	30.28	7.00e-12	62.40
IUUC-Ate-010414	Aspergillus terreus	27.41	2.00e-29	122.00
IUUC-Ame-011763	Astyanax mexicanus	44.72	1.00e-58	219.00
IUUC-Bgr-011991	Blumeria graminis	32.21	3.00e-20	92.00
IUUC-Bta-012373	Bos taurus	42.21	2.00e-52	198.00
IUUC-Bci-013824	Botrytis cinerea	34.27	1.00e-30	126.00
IUUC-Bdi-014138	Brachypodium distachyon	69.08	1.00e-104	371.00
IUUC-Bol-016110	Brassica oleracea	97.59	2.00e-146	510.00
IUUC-Cel-018441	Caenorhabditis elegans	35.79	3.00e-42	164.00
IUUC-Cja-018854	Callithrix jacchus	44.72	2.00e-58	218.00
IUUC-Cfa-020523	Canis familiaris	42.67	2.00e-52	198.00
IUUC-Cpo-022196	Cavia porcellus	43.50	7.00e-57	213.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	44.92	8.00e-60	223.00
IUUC-Csa-023108	Chlorocebus sabaeus	44.31	5.00e-58	217.00
IUUC-Cho-024373	Choloepus hoffmanni	43.09	4.00e-53	200.00
IUUC-Cin-025269	Ciona intestinalis	42.51	7.00e-59	219.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	27.91	7.00e-17	80.10
IUUC-Cne-026950	Cryptococcus neoformans	35.40	2.00e-36	145.00
IUUC-Dre-028247	Danio rerio	44.72	2.00e-58	218.00
IUUC-Dno-028974	Dasypus novemcinctus	43.72	7.00e-58	216.00
IUUC-Dor-030143	Dipodomys ordii	44.31	6.00e-58	216.00
IUUC-Dse-031365	Dothistroma septosporum	29.96	3.00e-26	111.00
IUUC-Dme-032197	Drosophila melanogaster	40.76	8.00e-55	206.00
IUUC-Ete-032371	Echinops telfairi	43.50	4.00e-57	214.00
IUUC-Eca-033242	Equus caballus	43.50	4.00e-57	214.00
IUUC-Eeu-035317	Erinaceus europaeus	43.90	2.00e-57	214.00
IUUC-Fca-036061	Felis catus	43.32	4.00e-57	214.00
IUUC-Fal-036715	Ficedula albicollis	44.72	3.00e-58	217.00
IUUC-Fox-037884	Fusarium oxysporum	31.33	8.00e-15	72.80
IUUC-Fso-038150	Fusarium solani	25.17	5.00e-18	84.70
IUUC-Gmo-038750	Gadus morhua	45.12	5.00e-58	217.00
IUUC-Ggr-039959	Gaeumannomyces graminis	27.23	5.00e-16	79.30
IUUC-Gga-040935	Gallus gallus	43.72	1.00e-57	216.00
IUUC-Gac-041937	Gasterosteus aculeatus	44.31	2.00e-57	215.00
IUUC-Gma-043545	Glycine max	75.00	5.00e-115	406.00
IUUC-Ggo-044972	Gorilla gorilla	44.53	3.00e-58	218.00
IUUC-Hsa-046994	Homo sapiens	44.53	1.00e-58	219.00
IUUC-Hvu-047636	Hordeum vulgare	38.83	4.00e-21	94.00
IUUC-Itr-047902	Ictidomys tridecemlineatus	44.31	3.00e-57	214.00
IUUC-Kpa-049127	Komagataella pastoris	31.76	8.00e-29	120.00
IUUC-Lch-049751	Latimeria chalumnae	45.75	2.00e-59	221.00
IUUC-Lpe-051540	Leersia perrieri	70.85	7.00e-107	379.00
IUUC-Loc-051976	Lepisosteus oculatus	44.53	5.00e-58	217.00
IUUC-Lma-053103	Leptosphaeria maculans	29.02	4.00e-25	108.00
IUUC-Laf-053972	Loxodonta africana	45.53	3.00e-59	221.00
IUUC-Mcc-054700	Macaca mulatta	44.53	1.00e-58	219.00
IUUC-Meu-056791	Macropus eugenii	38.37	3.00e-43	168.00
IUUC-Mor-056909	Magnaporthe oryzae	28.96	1.00e-23	102.00
IUUC-Mpo-057299	Magnaporthe poae	26.84	1.00e-21	96.70
IUUC-Mtr-057964	Medicago truncatula	76.02	3.00e-114	404.00
IUUC-Mla-058990	Melampsora laricipopulina	26.49	6.00e-17	81.30
IUUC-Mga-060072	Meleagris gallopavo	45.12	2.00e-58	218.00
IUUC-Mvi-060312	Microbotryum violaceum	33.20	1.00e-37	149.00
IUUC-Mmr-060851	Microcebus murinus	43.50	5.00e-57	213.00
IUUC-Mmu-063816	Mus musculus	44.53	6.00e-59	219.00
IUUC-Mac-065016	Musa acuminata	78.89	2.00e-86	310.00
IUUC-Mpu-066870	Mustela putorius furo	42.67	2.00e-52	198.00
IUUC-Mlu-067701	Myotis lucifugus	43.09	4.00e-56	210.00
IUUC-Nfi-068610	Neosartorya fischeri	28.49	2.00e-19	88.60
IUUC-Ncr-068780	Neurospora crassa	25.19	1.00e-18	86.70
IUUC-Nle-069475	Nomascus leucogenys	44.53	3.00e-58	218.00
IUUC-Opr-070682	Ochotona princeps	41.12	1.00e-42	166.00
IUUC-Ont-071813	Oreochromis niloticus	44.31	6.00e-58	216.00
IUUC-Oan-073031	Ornithorhynchus anatinus	43.90	3.00e-57	214.00
IUUC-Ocu-074648	Oryctolagus cuniculus	43.50	4.00e-57	214.00
IUUC-Oba-074993	Oryza barthii	71.37	4.00e-108	383.00
IUUC-Obr-076341	Oryza brachyantha	70.97	2.00e-108	384.00
IUUC-Ogl-077099	Oryza glaberrima	71.37	4.00e-108	383.00
IUUC-Ogu-078285	Oryza glumaepatula	71.37	3.00e-108	384.00
IUUC-Oin-079441	Oryza indica	71.77	1.00e-108	384.00
IUUC-Olo-081037	Oryza longistaminata	71.77	1.00e-108	384.00
IUUC-Ome-081357	Oryza meridionalis	71.77	1.00e-108	384.00
IUUC-Oni-082632	Oryza nivara	71.77	2.00e-108	384.00
IUUC-Opu-083351	Oryza punctata	71.24	6.00e-101	359.00
IUUC-Oru-084306	Oryza rufipogon	71.77	1.00e-108	384.00
IUUC-Osa-085307	Oryza sativa	71.77	1.00e-108	384.00
IUUC-Ola-086868	Oryzias latipes	43.90	3.00e-58	218.00
IUUC-Olu-087646	Ostreococcus lucimarinus	42.28	3.00e-53	201.00
IUUC-Oga-088621	Otolemur garnettii	44.31	8.00e-58	216.00
IUUC-Oar-090405	Ovis aries	43.09	2.00e-56	212.00
IUUC-Ptr-091595	Pan troglodytes	44.31	2.00e-57	214.00
IUUC-Pan-092825	Papio anubis	44.53	8.00e-59	219.00
IUUC-Psi-093110	Pelodiscus sinensis	42.67	8.00e-52	196.00
IUUC-Pma-094196	Petromyzon marinus	40.64	2.00e-42	166.00
IUUC-Pno-095145	Phaeosphaeria nodorum	30.30	6.00e-21	94.40
IUUC-Ppa-095306	Physcomitrella patens	72.06	7.00e-109	386.00
IUUC-Pfo-096774	Poecilia formosa	44.49	2.00e-58	219.00
IUUC-Pab-098197	Pongo abelii	43.10	6.00e-52	196.00
IUUC-Pop-098821	Populus trichocarpa	84.07	4.00e-56	209.00
IUUC-Pca-100218	Procavia capensis	43.09	5.00e-57	213.00
IUUC-Ppe-102032	Prunus persica	76.31	3.00e-117	413.00
IUUC-Pva-102691	Pteropus vampyrus	45.34	2.00e-59	221.00
IUUC-Pgr-103633	Puccinia graminis	28.37	1.00e-22	99.80
IUUC-Ptt-103979	Puccinia triticina	31.88	2.00e-03	36.60
IUUC-Pyt-104428	Pyrenophora triticirepentis	29.05	2.00e-22	99.00
IUUC-Rno-105016	Rattus norvegicus	44.94	5.00e-59	220.00
IUUC-Sce-106358	Saccharomyces cerevisiae	27.13	4.00e-21	94.70
IUUC-Sha-106888	Sarcophilus harrisii	43.50	4.00e-57	214.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	30.74	6.00e-23	100.00
IUUC-Spo-108207	Schizosaccharomyces pombe	34.91	2.00e-24	105.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	32.81	1.00e-29	123.00
IUUC-Smo-108750	Selaginella moellendorffii	64.75	2.00e-91	328.00
IUUC-Sit-110052	Setaria italica	72.98	6.00e-110	389.00
IUUC-Sly-111489	Solanum lycopersicum	78.54	2.00e-118	417.00
IUUC-Stu-112517	Solanum tuberosum	59.84	1.00e-92	332.00
IUUC-Sar-113509	Sorex araneus	43.60	2.00e-37	148.00
IUUC-Sbi-114113	Sorghum bicolor	72.58	1.00e-109	388.00
IUUC-Sre-115221	Sporisorium reilianum	26.13	8.00e-24	103.00
IUUC-Ssc-115547	Sus scrofa	43.72	7.00e-58	216.00
IUUC-Tgu-117196	Taeniopygia guttata	44.31	5.00e-58	217.00
IUUC-Tru-117740	Takifugu rubripes	45.71	6.00e-59	220.00
IUUC-Tsy-119599	Tarsius syrichta	43.50	4.00e-57	214.00
IUUC-Tni-120315	Tetraodon nigroviridis	43.50	2.00e-56	211.00
IUUC-Tca-121033	Theobroma cacao	78.23	1.00e-119	421.00
IUUC-Tre-121986	Trichoderma reesei	26.01	3.00e-21	95.50
IUUC-Tvi-122607	Trichoderma virens	32.16	2.00e-26	112.00
IUUC-Tae-125740	Triticum aestivum	59.66	8.00e-100	356.00
IUUC-Tur-126375	Triticum urartu	53.92	1.00e-94	339.00
IUUC-Tme-126878	Tuber melanosporum	31.50	7.00e-33	134.00
IUUC-Tbe-127429	Tupaia belangeri	41.12	3.00e-42	165.00
IUUC-Ttr-129086	Tursiops truncatus	39.84	1.00e-48	186.00
IUUC-Uma-129364	Ustilago maydis	27.18	5.00e-30	124.00
IUUC-Vda-129929	Verticillium dahliae	29.72	9.00e-19	87.80
IUUC-Vpa-130048	Vicugna pacos	37.80	3.00e-43	168.00
IUUC-Vvi-130834	Vitis vinifera	77.51	2.00e-118	418.00
IUUC-Xtr-131888	Xenopus tropicalis	43.09	4.00e-57	214.00
IUUC-Xma-134122	Xiphophorus maculatus	44.31	2.00e-59	222.00
IUUC-Yli-134595	Yarrowia lipolytica	32.34	3.00e-33	134.00
IUUC-Zma-135864	Zea mays	73.17	3.00e-110	390.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence