iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033671

UUCD1 version

UUC-EqC-00145

Ensembl Protein ID

ENSECAP00000015617.1

UniProt Accession

F6S0S1; F6S0S1_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRAF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000017744.1	ENSECAT00000019097.1	ENSECAP00000015617.1
ENSECAG00000017744.1	ENSECAT00000019169.1	ENSECAP00000015678.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.30e-27	92.2	385	416
UBD/Beta-Prp	1.70e-44	152.4	380	660

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v+cl+  s  +ll sGs D+tikvWD+
   Q: 385  GHQGPVWCLCVySMgDLLFSGSSDKTIKVWDT 416
           8*********778889***************6 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvw.dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
             ++ gh+++v++++  + g++l +gs+D+tikvw    t+kc  tl+gh+  vl+l ++    kl sGs+d ti vwd+++ q+++ t
   Q: 380  KGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWdTCTTYKCQKTLEGHDGIVLALCIQG--CKLYSGSADCTIIVWDIQNLQKVN-T 465
           5677788888888888888888888888888888833457888888888888887777766..888888888888888888888888.7 PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdl........................................ktgkllrtltgghtd 181
            + hd  v+++v++   n+l+sGsl +++++Wd+                                        +t ++++ l+    +
   Q: 466  IRAHDNPVCTLVSSH--NMLFSGSL-KAIKVWDIvgtelklkkeltglnhwvralvaaqsylqsgpllpiiwdiRTLDCIHVLQT-SGG 550
           888887777777777..88888888.678888888888888888888888888888888888888888888888*********99.*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssvi 268
           svys++++    ++v g + + + +wd++++e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv+
   Q: 551  SVYSIAVTN--HHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVT 637
           ********9..8***********************************99888************************************* PP
   S: 269  svavlsfgdnvlvlgsedskvniwkl 294
           + av   ++  l++g+ ds+v++w +
   Q: 638  ALAV---SRGRLFSGAVDSTVKVWTC 660
           ***9...*****************86 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSSGKSARGS RFSGGPSLPA PDAATGTRME TTFGPAFSAV TTITKADGTS TYKQHRRTPS 60
SSSTLAYSPR DEEDSMPPIS TPLRSDSAIS VRSLHSESSM SLRSTFSLPE EEEEPEPLVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTCGG GCAAGAGTGC CCGTGGCAGC CGCTTCTCCG GGGGGCCCAG CCTCCCTGCC 60
CCAGACGCCG CCACCGGGGT AAGGGACACC GCTGGTAGGG CTCTGTCCCC TGCACACACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:2001235--P:positive regulation of apoptotic signaling pathway
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	81.35	0.00e+00	964.00
IUUC-Apl-004098	Anas platyrhynchos	79.45	0.00e+00	927.00
IUUC-Aca-004852	Anolis carolinensis	71.38	0.00e+00	721.00
IUUC-Ame-011275	Astyanax mexicanus	68.01	0.00e+00	710.00
IUUC-Bta-013153	Bos taurus	82.49	0.00e+00	982.00
IUUC-Cja-019243	Callithrix jacchus	80.85	0.00e+00	939.00
IUUC-Cfa-020036	Canis familiaris	82.60	0.00e+00	994.00
IUUC-Cpo-022194	Cavia porcellus	82.12	0.00e+00	989.00
IUUC-Csa-023363	Chlorocebus sabaeus	82.64	0.00e+00	993.00
IUUC-Cin-025279	Ciona intestinalis	51.30	8.00e-178	617.00
IUUC-Csv-026163	Ciona savignyi	66.11	4.00e-164	570.00
IUUC-Dre-027998	Danio rerio	75.85	0.00e+00	870.00
IUUC-Dno-029356	Dasypus novemcinctus	68.95	7.00e-66	243.00
IUUC-Dor-030750	Dipodomys ordii	81.48	0.00e+00	979.00
IUUC-Eeu-034765	Erinaceus europaeus	95.39	1.00e-159	556.00
IUUC-Fca-035843	Felis catus	82.60	0.00e+00	994.00
IUUC-Fal-037237	Ficedula albicollis	78.12	0.00e+00	951.00
IUUC-Gmo-038779	Gadus morhua	87.07	0.00e+00	697.00
IUUC-Gga-040579	Gallus gallus	78.12	0.00e+00	951.00
IUUC-Gac-042233	Gasterosteus aculeatus	65.37	0.00e+00	743.00
IUUC-Gma-042914	Glycine max	27.27	1.00e-18	87.40
IUUC-Ggo-045147	Gorilla gorilla	82.20	0.00e+00	988.00
IUUC-Hsa-046117	Homo sapiens	82.20	0.00e+00	988.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	82.34	0.00e+00	995.00
IUUC-Lch-050593	Latimeria chalumnae	76.48	0.00e+00	927.00
IUUC-Loc-052444	Lepisosteus oculatus	76.06	0.00e+00	937.00
IUUC-Laf-053499	Loxodonta africana	76.43	0.00e+00	912.00
IUUC-Mcc-055038	Macaca mulatta	82.64	0.00e+00	993.00
IUUC-Meu-056610	Macropus eugenii	75.79	0.00e+00	683.00
IUUC-Mga-060183	Meleagris gallopavo	77.86	0.00e+00	948.00
IUUC-Mmr-061133	Microcebus murinus	79.91	0.00e+00	916.00
IUUC-Mdo-062312	Monodelphis domestica	80.59	0.00e+00	971.00
IUUC-Mmu-063844	Mus musculus	81.45	0.00e+00	951.00
IUUC-Mpu-066552	Mustela putorius furo	81.71	0.00e+00	959.00
IUUC-Mlu-067719	Myotis lucifugus	82.20	0.00e+00	990.00
IUUC-Nle-070045	Nomascus leucogenys	81.56	0.00e+00	911.00
IUUC-Opr-070927	Ochotona princeps	79.79	0.00e+00	936.00
IUUC-Ont-072680	Oreochromis niloticus	91.30	0.00e+00	751.00
IUUC-Oan-073521	Ornithorhynchus anatinus	94.95	6.00e-52	194.00
IUUC-Ogu-077987	Oryza glumaepatula	27.39	3.00e-16	79.70
IUUC-Oru-085210	Oryza rufipogon	26.80	1.00e-16	80.90
IUUC-Ola-087454	Oryzias latipes	75.80	0.00e+00	920.00
IUUC-Oga-088380	Otolemur garnettii	82.34	0.00e+00	991.00
IUUC-Oar-089558	Ovis aries	88.37	0.00e+00	726.00
IUUC-Ptr-091606	Pan troglodytes	82.20	0.00e+00	988.00
IUUC-Pan-092227	Papio anubis	82.64	0.00e+00	993.00
IUUC-Psi-093853	Pelodiscus sinensis	72.56	0.00e+00	775.00
IUUC-Pma-094541	Petromyzon marinus	80.84	3.00e-102	364.00
IUUC-Pfo-096237	Poecilia formosa	75.15	0.00e+00	872.00
IUUC-Pab-097589	Pongo abelii	82.34	0.00e+00	990.00
IUUC-Pca-100375	Procavia capensis	80.39	0.00e+00	935.00
IUUC-Pva-102434	Pteropus vampyrus	82.64	0.00e+00	998.00
IUUC-Rno-105443	Rattus norvegicus	81.75	0.00e+00	954.00
IUUC-Sha-106517	Sarcophilus harrisii	80.44	0.00e+00	972.00
IUUC-Ssc-115990	Sus scrofa	81.60	0.00e+00	983.00
IUUC-Tgu-117222	Taeniopygia guttata	77.88	0.00e+00	941.00
IUUC-Tru-118392	Takifugu rubripes	92.03	0.00e+00	757.00
IUUC-Tni-120220	Tetraodon nigroviridis	91.55	0.00e+00	752.00
IUUC-Tca-121793	Theobroma cacao	28.21	2.00e-19	90.10
IUUC-Tur-126339	Triticum urartu	26.80	2.00e-17	84.00
IUUC-Tbe-128045	Tupaia belangeri	97.22	9.00e-156	543.00
IUUC-Ttr-128203	Tursiops truncatus	79.53	0.00e+00	933.00
IUUC-Xtr-132043	Xenopus tropicalis	77.04	0.00e+00	983.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence