iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045367

UUCD1 version

UUC-GoG-01126

Ensembl Protein ID

ENSGGOP00000019301.1

UniProt Accession

G3RU24; G3RU24_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000004749.2	ENSGGOT00000027638.1	ENSGGOP00000019301.1
ENSGGOG00000004749.2	ENSGGOT00000004779.2	ENSGGOP00000004659.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-62	211.9	89	381
ULD/UDP/UBQ/UBQ_Other	1.20e-10	41.5	943	1005

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkea 81
           +Gl+Nlg+tCY+N  LQ+ +   elr++l               ++ee ++ + ++++++lq lf+ l++s++++++p+ ++kal+   
   Q: 89   VGLTNLGATCYVNTFLQVWFLNLELRQALYLcpstcsdyMLGDGIQEE-KDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG--- 173
           6*****************************955555544333333333.367888******************************9... PP
   S: 82   eefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
             +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++s+  ++f+
   Q: 174  --LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFY 237
           ..78899*******************.......................457889999******************************* PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           +l+l+++g++     +l+dc+++f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++    ++k++    f ++ 
   Q: 238  ELELNIQGHK-----QLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDSLPFLKKKLTIFSGFLKNN 321
           **********.....9************************************************************9999999997778 PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevl 323
           d  pf      +   ++ YeL+av++H G s+ sGHY+a+vk+ ++g+W++f+D+ +++++ ++ +
   Q: 322  DFLPFSPG---G---SYVYELSAVLIHRGvSAYSGHYIAHVKDpQSGEWYKFNDEDIEKMEGKKLQ 381
           88877766...2...79**************************44555***********9877765 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++GkiL +d+ tL+ +g+ ++s+i+l  +++
   Q: 943  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILsDDCATLGTLGVIPESVILLKADEP 1005
           344489999************************************************988775 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCKG NPNCLVGIGE 60
HIWLGEIDEN SFHNIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCCGC GGCTGCAGCT GGAGAAGGCG GCCTGGCGCT GGGCGGAGAC GGTGCGGCCC 60
GAGGAGGTGT CGCAGGAGCA CATCGAGACC GCTTACCGCA TCTGGCTGGA GCCCTGCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	31.82	3.00e-75	276.00
IUUC-Aml-001357	Ailuropoda melanoleuca	92.88	0.00e+00	1932.00
IUUC-Atr-002976	Amborella trichopoda	30.79	7.00e-72	265.00
IUUC-Apl-003773	Anas platyrhynchos	82.78	0.00e+00	1566.00
IUUC-Aca-004466	Anolis carolinensis	73.92	0.00e+00	764.00
IUUC-Aly-006249	Arabidopsis lyrata	29.05	5.00e-68	253.00
IUUC-Ath-006700	Arabidopsis thaliana	36.53	1.00e-56	215.00
IUUC-Ame-011554	Astyanax mexicanus	65.60	0.00e+00	1356.00
IUUC-Bta-012573	Bos taurus	92.31	0.00e+00	1927.00
IUUC-Bdi-014149	Brachypodium distachyon	31.36	3.00e-71	263.00
IUUC-Bol-016289	Brassica oleracea	38.04	2.00e-54	207.00
IUUC-Bra-017205	Brassica rapa	28.71	1.00e-63	238.00
IUUC-Cel-018662	Caenorhabditis elegans	28.15	9.00e-29	122.00
IUUC-Cja-019991	Callithrix jacchus	92.30	0.00e+00	1939.00
IUUC-Cfa-020294	Canis familiaris	93.45	0.00e+00	1959.00
IUUC-Cpo-021706	Cavia porcellus	90.24	0.00e+00	1817.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	33.59	8.00e-43	170.00
IUUC-Csa-023931	Chlorocebus sabaeus	94.50	0.00e+00	1964.00
IUUC-Cho-024566	Choloepus hoffmanni	98.19	2.00e-161	563.00
IUUC-Cin-025307	Ciona intestinalis	47.49	5.00e-76	277.00
IUUC-Csv-026006	Ciona savignyi	35.74	2.00e-140	493.00
IUUC-Cne-027065	Cryptococcus neoformans	28.15	1.00e-62	234.00
IUUC-Dre-027624	Danio rerio	66.35	0.00e+00	1402.00
IUUC-Dno-029633	Dasypus novemcinctus	88.97	0.00e+00	1181.00
IUUC-Dor-030809	Dipodomys ordii	93.25	0.00e+00	640.00
IUUC-Ete-032818	Echinops telfairi	85.43	0.00e+00	869.00
IUUC-Eca-033692	Equus caballus	93.06	0.00e+00	1947.00
IUUC-Eeu-035185	Erinaceus europaeus	75.14	0.00e+00	804.00
IUUC-Fca-035676	Felis catus	93.06	0.00e+00	1955.00
IUUC-Fal-036913	Ficedula albicollis	82.50	0.00e+00	1708.00
IUUC-Gmo-038532	Gadus morhua	62.80	0.00e+00	1299.00
IUUC-Gga-041041	Gallus gallus	82.69	0.00e+00	1702.00
IUUC-Gac-042570	Gasterosteus aculeatus	63.37	0.00e+00	1335.00
IUUC-Gma-044136	Glycine max	40.11	5.00e-64	239.00
IUUC-Hsa-046019	Homo sapiens	94.70	0.00e+00	1968.00
IUUC-Hvu-047303	Hordeum vulgare	32.71	1.00e-58	220.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	89.97	0.00e+00	1918.00
IUUC-Lch-049989	Latimeria chalumnae	72.78	0.00e+00	1531.00
IUUC-Lpe-051612	Leersia perrieri	32.03	1.00e-73	271.00
IUUC-Loc-052756	Lepisosteus oculatus	67.93	0.00e+00	1447.00
IUUC-Laf-054043	Loxodonta africana	91.10	0.00e+00	1932.00
IUUC-Mcc-054986	Macaca mulatta	93.16	0.00e+00	1948.00
IUUC-Meu-056228	Macropus eugenii	77.44	0.00e+00	862.00
IUUC-Mtr-058762	Medicago truncatula	28.88	3.00e-81	296.00
IUUC-Mga-059896	Meleagris gallopavo	81.57	0.00e+00	1601.00
IUUC-Mvi-060269	Microbotryum violaceum	35.90	2.00e-56	214.00
IUUC-Mmr-060887	Microcebus murinus	92.87	0.00e+00	1942.00
IUUC-Mdo-062506	Monodelphis domestica	88.82	0.00e+00	1856.00
IUUC-Mmu-063642	Mus musculus	87.69	0.00e+00	1879.00
IUUC-Mac-064896	Musa acuminata	31.29	2.00e-70	261.00
IUUC-Mpu-066194	Mustela putorius furo	92.87	0.00e+00	1935.00
IUUC-Mlu-067233	Myotis lucifugus	91.79	0.00e+00	1920.00
IUUC-Nle-069052	Nomascus leucogenys	93.61	0.00e+00	1954.00
IUUC-Opr-070890	Ochotona princeps	86.87	0.00e+00	1115.00
IUUC-Ont-071450	Oreochromis niloticus	62.75	0.00e+00	1288.00
IUUC-Oan-073252	Ornithorhynchus anatinus	88.89	0.00e+00	1056.00
IUUC-Ocu-073796	Oryctolagus cuniculus	91.66	0.00e+00	1630.00
IUUC-Oba-075563	Oryza barthii	32.40	4.00e-74	273.00
IUUC-Obr-076394	Oryza brachyantha	38.11	2.00e-57	217.00
IUUC-Ogl-077339	Oryza glaberrima	38.91	5.00e-41	161.00
IUUC-Ogu-079007	Oryza glumaepatula	32.93	2.00e-66	247.00
IUUC-Oin-079997	Oryza indica	32.40	2.00e-74	274.00
IUUC-Olo-080364	Oryza longistaminata	32.40	3.00e-74	273.00
IUUC-Ome-081165	Oryza meridionalis	32.99	6.00e-67	249.00
IUUC-Oni-083026	Oryza nivara	32.40	2.00e-74	274.00
IUUC-Opu-083284	Oryza punctata	32.87	3.00e-65	243.00
IUUC-Oru-084797	Oryza rufipogon	32.40	2.00e-74	274.00
IUUC-Osa-086221	Oryza sativa	38.91	5.00e-41	161.00
IUUC-Ola-086568	Oryzias latipes	63.56	0.00e+00	1339.00
IUUC-Oga-088687	Otolemur garnettii	91.15	0.00e+00	1920.00
IUUC-Oar-090345	Ovis aries	91.87	0.00e+00	1828.00
IUUC-Ptr-090734	Pan troglodytes	94.70	0.00e+00	1967.00
IUUC-Pan-091704	Papio anubis	93.76	0.00e+00	1936.00
IUUC-Psi-092937	Pelodiscus sinensis	82.48	0.00e+00	1483.00
IUUC-Ppa-095808	Physcomitrella patens	36.04	5.00e-47	183.00
IUUC-Pab-098129	Pongo abelii	94.79	0.00e+00	1969.00
IUUC-Pop-099738	Populus trichocarpa	26.58	4.00e-73	270.00
IUUC-Pca-100647	Procavia capensis	95.90	0.00e+00	644.00
IUUC-Ppe-102091	Prunus persica	40.86	8.00e-63	235.00
IUUC-Pva-102719	Pteropus vampyrus	92.49	0.00e+00	1929.00
IUUC-Rno-105363	Rattus norvegicus	90.17	0.00e+00	1901.00
IUUC-Sha-107620	Sarcophilus harrisii	84.97	0.00e+00	1717.00
IUUC-Smo-109487	Selaginella moellendorffii	27.52	3.00e-77	283.00
IUUC-Sit-110683	Setaria italica	32.39	6.00e-75	276.00
IUUC-Sly-111377	Solanum lycopersicum	28.85	2.00e-69	257.00
IUUC-Stu-111969	Solanum tuberosum	35.50	3.00e-60	226.00
IUUC-Sar-113099	Sorex araneus	90.89	0.00e+00	1599.00
IUUC-Sbi-113833	Sorghum bicolor	41.01	3.00e-55	208.00
IUUC-Ssc-115279	Sus scrofa	84.58	0.00e+00	1229.00
IUUC-Tgu-117519	Taeniopygia guttata	79.84	0.00e+00	1557.00
IUUC-Tru-117651	Takifugu rubripes	63.34	0.00e+00	1330.00
IUUC-Tsy-119201	Tarsius syrichta	88.82	0.00e+00	1684.00
IUUC-Tni-120840	Tetraodon nigroviridis	64.45	0.00e+00	1352.00
IUUC-Tca-121674	Theobroma cacao	28.05	3.00e-77	283.00
IUUC-Tae-125247	Triticum aestivum	26.06	4.00e-78	286.00
IUUC-Tur-126599	Triticum urartu	31.60	1.00e-73	271.00
IUUC-Tbe-127782	Tupaia belangeri	84.74	0.00e+00	1127.00
IUUC-Ttr-128312	Tursiops truncatus	91.62	0.00e+00	1906.00
IUUC-Vpa-130348	Vicugna pacos	92.45	0.00e+00	1838.00
IUUC-Vvi-131353	Vitis vinifera	30.83	3.00e-76	280.00
IUUC-Xtr-132172	Xenopus tropicalis	66.90	0.00e+00	1248.00
IUUC-Xma-133263	Xiphophorus maculatus	64.96	0.00e+00	1311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence