iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005650.3	ENSMMUT00000007947.3	ENSMMUP00000007470.3
ENSMMUG00000005650.3	ENSMMUT00000069660.1	ENSMMUP00000045934.1
ENSMMUG00000005650.3	ENSMMUT00000073862.1	ENSMMUP00000042957.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.80e-79	267.1	51	490

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  +++a s+++l+++++++++e  +
   Q: 51   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSFEDKDKPDakvrIIPLQLQRLFAQLLLLDQEAASTTDLTDSFGWTSNE--E 137
           9*****************************888877665543322234458899******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+n+s+r+e+fldl+++
   Q: 138  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTIVNQIVCKECKNISERQEDFLDLTVA 200
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++++n y+c +c+++++a k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 201  VKNVS-----GLEDALwNMYVEEEVFDCDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKP 284
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e ++  ++ Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 285  FCEQNELDDL-EYMYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfqeekskpdvnlkdlqseeeidhplmilkailleennlipvdq 372
           ****999987.9***************************************************************************** PP
   S: 302  ................................................................................ekgk..Wll 308
                                                                                           +  +  W+ 
   Q: 373  lgqkllkkigiswnkkyrkqhgplrkflqlhsqifllssdesivrllkngslqaesdfqrndqqifetlppespglnssiS--CphWFD 459
           ******************************************************999999999999888888877655433..156*** PP
   S: 309  fdDskVtevkeeevleetg..staYvlfYkr 337
           ++DskV++++e++++++ +  ++aY+lfY++
   Q: 460  INDSKVQPIREKDIEQQFQgkESAYMLFYRK 490
           ****************9889*********98 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

FLRVVFSFTM FGDLFEEEYS TVSNNQYGKG KKLKTKALEP PAPREFTNLS GIRNQGGTCY 60
LNSLLQTLHF TPEFREALFS LGPEELGSFE DKDKPDAKVR IIPLQLQRLF AQLLLLDQEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCGGCGC TCCCGCGGGG CATCCTGGGA AGCATAGTCC ACGATCCATA AATCACTTTC 60
AGGAGACCCG CCCTCGCCAA CATGGCGGCG CCCAGTTGGG GCGGGTTCGT TCGCTTCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	84.45	0.00e+00	1966.00
IUUC-Apl-004105	Anas platyrhynchos	64.46	0.00e+00	1554.00
IUUC-Aca-004715	Anolis carolinensis	62.86	0.00e+00	1493.00
IUUC-Ame-011073	Astyanax mexicanus	48.17	0.00e+00	1041.00
IUUC-Bta-012487	Bos taurus	83.50	0.00e+00	2022.00
IUUC-Cja-018937	Callithrix jacchus	93.37	0.00e+00	2292.00
IUUC-Cfa-020645	Canis familiaris	79.95	0.00e+00	1263.00
IUUC-Cpo-022160	Cavia porcellus	79.97	0.00e+00	1956.00
IUUC-Csa-023078	Chlorocebus sabaeus	98.06	0.00e+00	2460.00
IUUC-Cho-025013	Choloepus hoffmanni	67.19	0.00e+00	836.00
IUUC-Csv-026193	Ciona savignyi	56.90	8.00e-59	219.00
IUUC-Dre-027416	Danio rerio	49.22	0.00e+00	1137.00
IUUC-Dno-029639	Dasypus novemcinctus	80.63	0.00e+00	1672.00
IUUC-Dor-030624	Dipodomys ordii	91.67	6.00e-156	545.00
IUUC-Ete-032626	Echinops telfairi	63.90	0.00e+00	748.00
IUUC-Eca-034208	Equus caballus	85.26	0.00e+00	2107.00
IUUC-Eeu-035340	Erinaceus europaeus	45.68	1.00e-90	328.00
IUUC-Fca-035886	Felis catus	74.27	0.00e+00	780.00
IUUC-Fal-036925	Ficedula albicollis	64.50	0.00e+00	1459.00
IUUC-Gmo-038597	Gadus morhua	46.04	0.00e+00	892.00
IUUC-Gga-041171	Gallus gallus	64.58	0.00e+00	1560.00
IUUC-Gac-041362	Gasterosteus aculeatus	45.64	0.00e+00	947.00
IUUC-Ggo-045069	Gorilla gorilla	94.70	0.00e+00	2179.00
IUUC-Hsa-046715	Homo sapiens	96.30	0.00e+00	2399.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	81.45	0.00e+00	1952.00
IUUC-Lch-050182	Latimeria chalumnae	52.58	0.00e+00	1166.00
IUUC-Loc-052705	Lepisosteus oculatus	54.57	0.00e+00	1264.00
IUUC-Laf-054132	Loxodonta africana	82.05	0.00e+00	2034.00
IUUC-Meu-056135	Macropus eugenii	86.70	5.00e-115	409.00
IUUC-Mga-060092	Meleagris gallopavo	64.22	0.00e+00	1523.00
IUUC-Mmr-061546	Microcebus murinus	84.78	0.00e+00	2063.00
IUUC-Mdo-061935	Monodelphis domestica	62.33	0.00e+00	1510.00
IUUC-Mmu-063630	Mus musculus	79.55	0.00e+00	1962.00
IUUC-Mpu-066579	Mustela putorius furo	79.79	0.00e+00	2011.00
IUUC-Mlu-068034	Myotis lucifugus	84.07	0.00e+00	2006.00
IUUC-Nle-069082	Nomascus leucogenys	95.35	0.00e+00	1991.00
IUUC-Opr-070953	Ochotona princeps	71.75	0.00e+00	978.00
IUUC-Ont-072435	Oreochromis niloticus	47.15	0.00e+00	1080.00
IUUC-Oan-073339	Ornithorhynchus anatinus	67.06	0.00e+00	1563.00
IUUC-Ocu-073760	Oryctolagus cuniculus	81.80	0.00e+00	2013.00
IUUC-Ola-087015	Oryzias latipes	47.10	0.00e+00	911.00
IUUC-Oga-088960	Otolemur garnettii	86.24	0.00e+00	2116.00
IUUC-Oar-089853	Ovis aries	83.84	0.00e+00	2050.00
IUUC-Ptr-091093	Pan troglodytes	96.14	0.00e+00	2396.00
IUUC-Pan-091962	Papio anubis	98.06	0.00e+00	2457.00
IUUC-Psi-093691	Pelodiscus sinensis	66.19	0.00e+00	1601.00
IUUC-Pma-094428	Petromyzon marinus	64.75	3.00e-91	328.00
IUUC-Pfo-096983	Poecilia formosa	47.90	0.00e+00	1012.00
IUUC-Pab-097860	Pongo abelii	95.71	0.00e+00	2215.00
IUUC-Pca-100514	Procavia capensis	79.73	0.00e+00	662.00
IUUC-Pva-102771	Pteropus vampyrus	83.88	0.00e+00	1915.00
IUUC-Rno-105405	Rattus norvegicus	78.25	0.00e+00	1900.00
IUUC-Sha-107376	Sarcophilus harrisii	64.72	0.00e+00	1481.00
IUUC-Ssc-115819	Sus scrofa	79.06	0.00e+00	1396.00
IUUC-Tgu-117262	Taeniopygia guttata	63.10	0.00e+00	1523.00
IUUC-Tru-117601	Takifugu rubripes	48.42	0.00e+00	1089.00
IUUC-Tsy-118996	Tarsius syrichta	76.69	0.00e+00	1670.00
IUUC-Tni-120682	Tetraodon nigroviridis	43.02	0.00e+00	868.00
IUUC-Tbe-127616	Tupaia belangeri	67.09	0.00e+00	1147.00
IUUC-Ttr-129075	Tursiops truncatus	81.41	0.00e+00	1890.00
IUUC-Vpa-130108	Vicugna pacos	83.89	0.00e+00	1825.00
IUUC-Xtr-132623	Xenopus tropicalis	53.24	0.00e+00	1219.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence