iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054828

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Putative uncharacterized protein

Genbank Nucleotide ID

JSUE03011586

Gene Name

LONRF2; EGK_05611

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000017455.2	ENSMMUT00000024547.2	ENSMMUP00000022977.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-06	28.7	206	244
E3 activity/RING/U-box	9.10e-07	30.0	203	249

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C+  +++ p+++pCgH+f+++Cl++          + +CPlC+
   Q: 206  CALCMRLLFE-PVTTPCGHTFCLKCLERC------LDHAPHCPLCK 244
           **********.9**************999......9*********7 PP

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           +f C++ + l  +Pv++p+G+t+  +++e++l++  + cP+++ +l+e
   Q: 203  DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPH-CPLCKDKLSE 249
           79***********************************.******9976 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MKNYEQAFQD ASAVCQNEPL LIKGHQVKAQ ALSGLGRSKE VLKQFLYCLA LNPECNSMKK 60
EAQKVMCEVL FSATENVHEN LTSSIQSRLK AQGHSHMNAQ ALLEERDAGS SENSSEKSDM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACCGCGCTC CCGCAGACCA GTTCCAGCAG CAGCGCGTCC TCCCTGCTCC GCGCCTTCGC 60
TCCGGACCCG CGTCGTCGCA GCCCCGCGGT GATGAGCCCC GAGCCGGTCC CGCCGCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR011990--TPR-like_helical_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001867	Ailuropoda melanoleuca	86.27	0.00e+00	889.00
IUUC-Apl-003355	Anas platyrhynchos	63.67	0.00e+00	679.00
IUUC-Aca-004822	Anolis carolinensis	62.65	0.00e+00	659.00
IUUC-Acl-008224	Aspergillus clavatus	32.26	2.00e-41	163.00
IUUC-Afu-008802	Aspergillus fumigatus	30.00	2.00e-37	150.00
IUUC-Ani-009473	Aspergillus nidulans	32.09	2.00e-41	164.00
IUUC-Ang-009643	Aspergillus niger	28.99	3.00e-38	153.00
IUUC-Ate-010489	Aspergillus terreus	32.40	2.00e-39	157.00
IUUC-Ame-010750	Astyanax mexicanus	54.97	4.00e-150	525.00
IUUC-Cja-019041	Callithrix jacchus	92.59	0.00e+00	951.00
IUUC-Cfa-020025	Canis familiaris	86.04	0.00e+00	865.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	49.09	2.00e-09	55.80
IUUC-Csa-023324	Chlorocebus sabaeus	98.63	0.00e+00	1015.00
IUUC-Cne-026875	Cryptococcus neoformans	28.57	3.00e-08	53.50
IUUC-Dre-028400	Danio rerio	50.79	5.00e-144	504.00
IUUC-Eeu-034779	Erinaceus europaeus	66.73	0.00e+00	644.00
IUUC-Fca-036276	Felis catus	86.10	0.00e+00	884.00
IUUC-Fal-036669	Ficedula albicollis	63.09	0.00e+00	676.00
IUUC-Fox-037926	Fusarium oxysporum	24.30	6.00e-10	57.80
IUUC-Fso-038334	Fusarium solani	29.77	3.00e-41	163.00
IUUC-Gmo-039511	Gadus morhua	69.13	1.00e-117	416.00
IUUC-Gga-041253	Gallus gallus	63.09	0.00e+00	669.00
IUUC-Gma-042919	Glycine max	34.21	6.00e-39	155.00
IUUC-Ggo-045501	Gorilla gorilla	98.04	0.00e+00	1009.00
IUUC-Hsa-046630	Homo sapiens	98.04	0.00e+00	1007.00
IUUC-Itr-048224	Ictidomys tridecemlineatus	81.23	0.00e+00	820.00
IUUC-Lch-049788	Latimeria chalumnae	56.35	6.00e-164	571.00
IUUC-Loc-051922	Lepisosteus oculatus	52.94	2.00e-151	529.00
IUUC-Laf-054421	Loxodonta africana	59.62	7.00e-174	603.00
IUUC-Meu-055901	Macropus eugenii	51.45	1.00e-149	523.00
IUUC-Mtr-058075	Medicago truncatula	35.43	2.00e-43	170.00
IUUC-Mga-059760	Meleagris gallopavo	62.00	0.00e+00	679.00
IUUC-Mmr-061350	Microcebus murinus	86.33	0.00e+00	879.00
IUUC-Mdo-062203	Monodelphis domestica	65.23	0.00e+00	692.00
IUUC-Mmu-064118	Mus musculus	78.42	0.00e+00	788.00
IUUC-Mpu-065764	Mustela putorius furo	85.52	0.00e+00	888.00
IUUC-Nfi-068337	Neosartorya fischeri	32.38	7.00e-38	151.00
IUUC-Nle-069616	Nomascus leucogenys	97.85	0.00e+00	1008.00
IUUC-Ont-072142	Oreochromis niloticus	52.52	4.00e-149	521.00
IUUC-Oga-088972	Otolemur garnettii	86.52	0.00e+00	893.00
IUUC-Ptr-090992	Pan troglodytes	98.04	0.00e+00	1011.00
IUUC-Pan-092180	Papio anubis	97.08	0.00e+00	992.00
IUUC-Psi-093423	Pelodiscus sinensis	62.62	0.00e+00	667.00
IUUC-Pfo-096363	Poecilia formosa	52.90	7.00e-145	508.00
IUUC-Pab-097974	Pongo abelii	97.65	0.00e+00	1003.00
IUUC-Ppe-101621	Prunus persica	39.49	5.00e-36	145.00
IUUC-Pva-102269	Pteropus vampyrus	79.15	0.00e+00	790.00
IUUC-Pgr-103289	Puccinia graminis	26.78	1.00e-27	118.00
IUUC-Rno-105905	Rattus norvegicus	79.34	0.00e+00	811.00
IUUC-Tgu-117000	Taeniopygia guttata	63.48	0.00e+00	678.00
IUUC-Tru-118016	Takifugu rubripes	51.77	6.00e-143	501.00
IUUC-Tni-119913	Tetraodon nigroviridis	51.20	2.00e-138	486.00
IUUC-Tre-121992	Trichoderma reesei	28.05	2.00e-07	50.10
IUUC-Ttr-128666	Tursiops truncatus	78.72	0.00e+00	792.00
IUUC-Uma-129541	Ustilago maydis	33.98	7.00e-34	139.00
IUUC-Vpa-130334	Vicugna pacos	63.76	1.00e-171	596.00
IUUC-Vvi-130910	Vitis vinifera	34.33	1.00e-39	157.00
IUUC-Xtr-132065	Xenopus tropicalis	55.86	5.00e-163	568.00
IUUC-Xma-134324	Xiphophorus maculatus	53.38	1.00e-146	513.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence