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Tag Content
iUUCD ID IUUC-Lch-050471
Ensembl Protein ID ENSLACP00000011946.1
UniProt Accession H3AQM5; H3AQM5_LATCH
Genbank Protein ID ENSLACP00000011946
Protein Name DNA repair protein REV1
Genbank Nucleotide ID AFYH01120228
Gene Name REV1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSLACG00000010515.1 ENSLACT00000012037.1 ENSLACP00000011946.1
ENSLACG00000010515.1 ENSLACT00000012038.1 ENSLACP00000011947.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 6.80e-20 70.3 952 980
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM
   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           +Psq+Dp+V+++LP++i+e+v++ +++++
   Q: 952  SPSQIDPSVLEALPPDIREQVEQTCSVRQ 980
           7*************************997 PP
   
Organism Latimeria chalumnae
Functional Description
(View)

Functional Description


     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
 Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MSRGGWRKRA NEGDGWGGRG GYMVAKVQKL EEQFKLDAPR QQQKEGTSSS LFNGVAIYVN 60
GYTDPTADEL RRLMMLHGGQ YHVYYSRSKT THIIATNLPN NKIKELKGEK VVRPEWITDS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Lch-050471|UBD,UBM|Latimeria chalumnae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGTTTGTC TGTCAGAGCG ACCCCAGCAG GAGGAGGGTC CGCGTCCGCT GCGAGCGGGA 60
GGAGGAGTCG GAGAGAAGGC GGCTGGTTCT GGATAGAGAG AAAGGAAAGA GAAGCAGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Lch-050471|UBD,UBM|Latimeria chalumnae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC
PROSITE

PS50172--BRCT
PS50173--UMUC
Pfam

PF16589--BRCT_2
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C
SMART

SM00292--BRCT
Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0016779--F:nucleotidyltransferase activity
GO:0042276--P:error-prone translesion synthesis
KEGG lcm:102359244
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 39.62 6.00e-33 136.00
IUUC-Aml-001185 Ailuropoda melanoleuca 65.19 0.00e+00 1527.00
IUUC-Atr-002915 Amborella trichopoda 34.38 4.00e-74 273.00
IUUC-Apl-004054 Anas platyrhynchos 65.60 0.00e+00 1506.00
IUUC-Aca-004304 Anolis carolinensis 63.13 0.00e+00 1478.00
IUUC-Aly-005696 Arabidopsis lyrata 33.77 1.00e-78 288.00
IUUC-Ath-006893 Arabidopsis thaliana 34.08 8.00e-80 292.00
IUUC-Ago-007722 Ashbya gossypii 30.10 5.00e-43 169.00
IUUC-Acl-008347 Aspergillus clavatus 37.70 3.00e-80 293.00
IUUC-Afl-008444 Aspergillus flavus 45.29 4.00e-77 283.00
IUUC-Afu-008837 Aspergillus fumigatus 35.14 4.00e-81 296.00
IUUC-Ani-009188 Aspergillus nidulans 44.44 7.00e-80 292.00
IUUC-Ang-009866 Aspergillus niger 35.75 1.00e-84 308.00
IUUC-Aor-010107 Aspergillus oryzae 45.29 4.00e-77 283.00
IUUC-Ate-010359 Aspergillus terreus 38.25 1.00e-83 305.00
IUUC-Ame-010664 Astyanax mexicanus 50.93 0.00e+00 1137.00
IUUC-Bgr-012244 Blumeria graminis 28.77 4.00e-76 280.00
IUUC-Bta-013405 Bos taurus 61.76 0.00e+00 1332.00
IUUC-Bci-013849 Botrytis cinerea 35.82 1.00e-83 305.00
IUUC-Bdi-014066 Brachypodium distachyon 44.51 3.00e-79 290.00
IUUC-Bol-015544 Brassica oleracea 44.51 6.00e-76 279.00
IUUC-Bra-017792 Brassica rapa 35.76 1.00e-76 281.00
IUUC-Cel-018148 Caenorhabditis elegans 33.20 4.00e-73 270.00
IUUC-Cja-019742 Callithrix jacchus 53.99 0.00e+00 995.00
IUUC-Cfa-020112 Canis familiaris 66.41 0.00e+00 1531.00
IUUC-Cpo-022152 Cavia porcellus 62.68 0.00e+00 1504.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 38.14 4.00e-40 159.00
IUUC-Csa-023504 Chlorocebus sabaeus 65.58 0.00e+00 1519.00
IUUC-Cho-024780 Choloepus hoffmanni 59.54 1.00e-132 467.00
IUUC-Cin-025276 Ciona intestinalis 52.83 8.00e-102 364.00
IUUC-Csv-026283 Ciona savignyi 44.20 3.00e-112 399.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 31.21 2.00e-86 314.00
IUUC-Cne-027079 Cryptococcus neoformans 32.68 5.00e-70 259.00
IUUC-Cme-027346 Cyanidioschyzon merolae 27.47 2.00e-41 164.00
IUUC-Dre-028073 Danio rerio 51.27 0.00e+00 1116.00
IUUC-Dno-030038 Dasypus novemcinctus 63.16 0.00e+00 1470.00
IUUC-Dor-031100 Dipodomys ordii 62.98 0.00e+00 1092.00
IUUC-Dse-031310 Dothistroma septosporum 33.91 1.00e-85 311.00
IUUC-Dme-031991 Drosophila melanogaster 36.70 7.00e-108 385.00
IUUC-Ete-033082 Echinops telfairi 61.12 0.00e+00 1063.00
IUUC-Eca-033471 Equus caballus 65.58 0.00e+00 1544.00
IUUC-Eeu-034993 Erinaceus europaeus 64.58 0.00e+00 1020.00
IUUC-Fca-035367 Felis catus 66.09 0.00e+00 1501.00
IUUC-Fal-036973 Ficedula albicollis 65.96 0.00e+00 1452.00
IUUC-Fox-037677 Fusarium oxysporum 33.98 2.00e-79 290.00
IUUC-Fso-038252 Fusarium solani 34.70 1.00e-82 301.00
IUUC-Gmo-039669 Gadus morhua 59.88 3.00e-174 605.00
IUUC-Ggr-039988 Gaeumannomyces graminis 34.85 5.00e-77 283.00
IUUC-Gga-040423 Gallus gallus 66.46 0.00e+00 1506.00
IUUC-Gac-042134 Gasterosteus aculeatus 51.83 0.00e+00 822.00
IUUC-Gma-042929 Glycine max 39.94 4.00e-73 270.00
IUUC-Ggo-044528 Gorilla gorilla 66.01 0.00e+00 1521.00
IUUC-Hsa-046259 Homo sapiens 66.09 0.00e+00 1502.00
IUUC-Hvu-047139 Hordeum vulgare 45.88 1.00e-45 177.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 66.02 0.00e+00 1550.00
IUUC-Kpa-049169 Komagataella pastoris 33.42 3.00e-57 216.00
IUUC-Lpe-050800 Leersia perrieri 36.91 6.00e-75 276.00
IUUC-Loc-052320 Lepisosteus oculatus 46.81 0.00e+00 920.00
IUUC-Lma-053149 Leptosphaeria maculans 32.42 1.00e-84 308.00
IUUC-Laf-053810 Loxodonta africana 63.62 0.00e+00 1416.00
IUUC-Mcc-055574 Macaca mulatta 65.78 0.00e+00 1494.00
IUUC-Meu-055945 Macropus eugenii 49.64 0.00e+00 798.00
IUUC-Mor-057195 Magnaporthe oryzae 33.87 3.00e-82 300.00
IUUC-Mpo-057488 Magnaporthe poae 34.46 5.00e-80 293.00
IUUC-Mtr-057955 Medicago truncatula 44.20 1.00e-77 285.00
IUUC-Mla-059027 Melampsora laricipopulina 34.78 2.00e-71 263.00
IUUC-Mga-060156 Meleagris gallopavo 66.30 0.00e+00 1529.00
IUUC-Mvi-060398 Microbotryum violaceum 36.16 2.00e-79 290.00
IUUC-Mmr-061113 Microcebus murinus 65.15 0.00e+00 1503.00
IUUC-Mdo-063001 Monodelphis domestica 66.28 0.00e+00 1518.00
IUUC-Mmu-063180 Mus musculus 63.81 0.00e+00 1470.00
IUUC-Mac-065551 Musa acuminata 41.76 2.00e-54 206.00
IUUC-Mpu-066525 Mustela putorius furo 65.73 0.00e+00 1531.00
IUUC-Mlu-067877 Myotis lucifugus 66.05 0.00e+00 1502.00
IUUC-Nfi-068418 Neosartorya fischeri 34.76 3.00e-85 310.00
IUUC-Ncr-068648 Neurospora crassa 36.01 6.00e-83 302.00
IUUC-Nle-069959 Nomascus leucogenys 66.25 0.00e+00 1508.00
IUUC-Opr-070522 Ochotona princeps 63.53 0.00e+00 884.00
IUUC-Ont-072293 Oreochromis niloticus 49.00 0.00e+00 832.00
IUUC-Oan-073519 Ornithorhynchus anatinus 64.65 0.00e+00 1509.00
IUUC-Ocu-074492 Oryctolagus cuniculus 62.63 0.00e+00 1385.00
IUUC-Oba-075567 Oryza barthii 37.25 3.00e-79 290.00
IUUC-Obr-076332 Oryza brachyantha 44.51 4.00e-77 283.00
IUUC-Ogl-077348 Oryza glaberrima 37.25 4.00e-79 290.00
IUUC-Ogu-078779 Oryza glumaepatula 37.04 7.00e-79 288.00
IUUC-Oin-079738 Oryza indica 33.40 3.00e-67 250.00
IUUC-Olo-080701 Oryza longistaminata 33.40 2.00e-67 250.00
IUUC-Ome-081708 Oryza meridionalis 37.72 7.00e-80 292.00
IUUC-Oni-082251 Oryza nivara 36.82 9.00e-77 281.00
IUUC-Opu-083528 Oryza punctata 27.94 2.00e-85 310.00
IUUC-Oru-084293 Oryza rufipogon 35.73 5.00e-74 272.00
IUUC-Osa-085549 Oryza sativa 37.04 1.00e-78 288.00
IUUC-Ola-086793 Oryzias latipes 52.37 0.00e+00 875.00
IUUC-Olu-087786 Ostreococcus lucimarinus 27.91 6.00e-54 205.00
IUUC-Oga-089006 Otolemur garnettii 64.93 0.00e+00 1504.00
IUUC-Oar-089597 Ovis aries 62.28 0.00e+00 1441.00
IUUC-Ptr-091520 Pan troglodytes 65.86 0.00e+00 1496.00
IUUC-Pan-092333 Papio anubis 65.93 0.00e+00 1491.00
IUUC-Psi-094004 Pelodiscus sinensis 66.69 0.00e+00 1551.00
IUUC-Pma-094128 Petromyzon marinus 53.31 2.00e-94 339.00
IUUC-Pno-094849 Phaeosphaeria nodorum 32.63 1.00e-73 271.00
IUUC-Ppa-095714 Physcomitrella patens 35.44 3.00e-82 300.00
IUUC-Pfo-096569 Poecilia formosa 51.54 0.00e+00 840.00
IUUC-Pab-097960 Pongo abelii 65.70 0.00e+00 1494.00
IUUC-Pop-098921 Populus trichocarpa 41.44 1.00e-73 271.00
IUUC-Pca-100509 Procavia capensis 53.24 0.00e+00 830.00
IUUC-Ppe-101730 Prunus persica 35.02 1.00e-82 301.00
IUUC-Pva-102142 Pteropus vampyrus 64.21 0.00e+00 1469.00
IUUC-Pgr-103446 Puccinia graminis 32.31 6.00e-69 255.00
IUUC-Ptt-103849 Puccinia triticina 29.64 8.00e-70 259.00
IUUC-Pte-104128 Pyrenophora teres 32.70 7.00e-79 289.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 34.96 5.00e-76 279.00
IUUC-Rno-104871 Rattus norvegicus 63.17 0.00e+00 1463.00
IUUC-Sce-106236 Saccharomyces cerevisiae 30.97 2.00e-36 147.00
IUUC-Sha-106962 Sarcophilus harrisii 65.44 0.00e+00 1489.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 36.73 5.00e-52 199.00
IUUC-Spo-108170 Schizosaccharomyces pombe 40.68 2.00e-55 210.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 32.01 4.00e-90 326.00
IUUC-Smo-109554 Selaginella moellendorffii 43.16 2.00e-72 267.00
IUUC-Sit-110479 Setaria italica 36.09 7.00e-73 268.00
IUUC-Sly-111752 Solanum lycopersicum 32.80 3.00e-76 280.00
IUUC-Sar-113304 Sorex araneus 64.85 0.00e+00 1506.00
IUUC-Sbi-114196 Sorghum bicolor 36.22 3.00e-74 273.00
IUUC-Sre-115151 Sporisorium reilianum 31.76 1.00e-80 295.00
IUUC-Ssc-116104 Sus scrofa 64.02 0.00e+00 1481.00
IUUC-Tgu-117438 Taeniopygia guttata 66.04 0.00e+00 1502.00
IUUC-Tru-118553 Takifugu rubripes 50.94 0.00e+00 814.00
IUUC-Tsy-119056 Tarsius syrichta 62.18 0.00e+00 1380.00
IUUC-Tni-119933 Tetraodon nigroviridis 46.54 0.00e+00 985.00
IUUC-Tca-121376 Theobroma cacao 43.07 5.00e-77 283.00
IUUC-Tre-121972 Trichoderma reesei 30.57 3.00e-77 283.00
IUUC-Tvi-122342 Trichoderma virens 34.90 1.00e-76 281.00
IUUC-Tae-123898 Triticum aestivum 44.20 3.00e-79 290.00
IUUC-Tur-126735 Triticum urartu 38.66 1.00e-36 148.00
IUUC-Tme-126999 Tuber melanosporum 37.79 2.00e-67 251.00
IUUC-Tbe-127280 Tupaia belangeri 63.92 6.00e-89 322.00
IUUC-Ttr-129104 Tursiops truncatus 64.60 0.00e+00 1477.00
IUUC-Uma-129562 Ustilago maydis 30.05 6.00e-81 296.00
IUUC-Vda-129862 Verticillium dahliae 34.05 2.00e-82 300.00
IUUC-Vpa-130819 Vicugna pacos 61.06 0.00e+00 758.00
IUUC-Vvi-131111 Vitis vinifera 43.57 1.00e-77 285.00
IUUC-Xtr-132629 Xenopus tropicalis 60.14 0.00e+00 1361.00
IUUC-Xma-134065 Xiphophorus maculatus 50.81 0.00e+00 827.00
IUUC-Yli-134633 Yarrowia lipolytica 37.68 5.00e-56 213.00
IUUC-Zma-135176 Zea mays 36.64 1.00e-77 285.00
Created Date 25-Jun-2017

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