iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074164

Ensembl Protein ID

ENSOCUP00000011159.2

UniProt Accession

G1T4F6; G1T4F6_RABIT

Genbank Protein ID

ENSOCUP00000011159

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02051714

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000012946.2	ENSOCUT00000012964.2	ENSOCUP00000011159.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.90e-18	66.4	334	381

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 334  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 381
           8*********88.6*******************.*******7.******75 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

AVLVREDALL SPCRDVRGLR GLRPAFSHLF PRGGPVVIAM AGVGPGGYAA EFVPPPECPV 60
FEPSWEEFTD PLSFIGRIRP LAEKTGICKI RPPKDWQPPF ACEVKSFRFT PRVQRLNELE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGTTCTCG TCCGAGAAGA TGCGCTGCTG TCCCCGTGCA GGGACGTGAG AGGGCTCCGT 60
GGGCTTCGGC CAGCCTTTTC CCACCTGTTC CCCCGTGGGG GCCCCGTGGT TATTGCCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	98.10	0.00e+00	2788.00
IUUC-Atr-002595	Amborella trichopoda	30.58	1.00e-124	442.00
IUUC-Apl-004141	Anas platyrhynchos	89.70	0.00e+00	2818.00
IUUC-Aca-004952	Anolis carolinensis	90.85	0.00e+00	2652.00
IUUC-Aly-006097	Arabidopsis lyrata	63.64	3.00e-09	58.50
IUUC-Ate-010453	Aspergillus terreus	29.43	9.00e-116	412.00
IUUC-Ame-011323	Astyanax mexicanus	76.27	0.00e+00	2071.00
IUUC-Bgr-012241	Blumeria graminis	30.41	2.00e-114	407.00
IUUC-Bta-012902	Bos taurus	94.80	0.00e+00	2996.00
IUUC-Bci-013992	Botrytis cinerea	33.20	1.00e-106	382.00
IUUC-Cja-018988	Callithrix jacchus	93.57	0.00e+00	2801.00
IUUC-Cfa-020212	Canis familiaris	96.98	0.00e+00	2748.00
IUUC-Cpo-022221	Cavia porcellus	95.27	0.00e+00	2100.00
IUUC-Csa-023575	Chlorocebus sabaeus	95.69	0.00e+00	2872.00
IUUC-Cho-024280	Choloepus hoffmanni	89.49	0.00e+00	2770.00
IUUC-Cin-025321	Ciona intestinalis	49.23	0.00e+00	1077.00
IUUC-Csv-026185	Ciona savignyi	48.12	0.00e+00	1172.00
IUUC-Dre-027909	Danio rerio	75.83	0.00e+00	1645.00
IUUC-Dno-029473	Dasypus novemcinctus	94.69	0.00e+00	2702.00
IUUC-Dor-030281	Dipodomys ordii	91.17	0.00e+00	1228.00
IUUC-Dme-032021	Drosophila melanogaster	47.09	0.00e+00	1123.00
IUUC-Eca-034265	Equus caballus	94.16	0.00e+00	2994.00
IUUC-Fca-035476	Felis catus	96.92	0.00e+00	2783.00
IUUC-Fal-037078	Ficedula albicollis	91.65	0.00e+00	2507.00
IUUC-Ggr-039929	Gaeumannomyces graminis	30.11	1.00e-109	391.00
IUUC-Gga-040466	Gallus gallus	91.58	0.00e+00	2727.00
IUUC-Gac-042566	Gasterosteus aculeatus	75.69	0.00e+00	2110.00
IUUC-Ggo-044524	Gorilla gorilla	88.74	0.00e+00	2512.00
IUUC-Hsa-045821	Homo sapiens	95.69	0.00e+00	2983.00
IUUC-Kpa-049245	Komagataella pastoris	22.93	3.00e-40	160.00
IUUC-Lch-050630	Latimeria chalumnae	74.50	0.00e+00	2120.00
IUUC-Loc-051963	Lepisosteus oculatus	75.98	0.00e+00	2068.00
IUUC-Laf-053918	Loxodonta africana	88.11	0.00e+00	2578.00
IUUC-Mcc-055672	Macaca mulatta	94.29	0.00e+00	2972.00
IUUC-Mor-057198	Magnaporthe oryzae	30.44	8.00e-120	425.00
IUUC-Mpo-057317	Magnaporthe poae	30.38	2.00e-110	394.00
IUUC-Mga-059192	Meleagris gallopavo	82.31	0.00e+00	2269.00
IUUC-Mmr-060968	Microcebus murinus	93.88	0.00e+00	2999.00
IUUC-Mdo-062945	Monodelphis domestica	92.74	0.00e+00	2782.00
IUUC-Mmu-063614	Mus musculus	93.79	0.00e+00	2939.00
IUUC-Mpu-066349	Mustela putorius furo	98.03	0.00e+00	2785.00
IUUC-Mlu-067363	Myotis lucifugus	95.27	0.00e+00	3043.00
IUUC-Nle-070142	Nomascus leucogenys	95.57	0.00e+00	2996.00
IUUC-Opr-071002	Ochotona princeps	91.36	0.00e+00	1400.00
IUUC-Ont-072471	Oreochromis niloticus	78.10	0.00e+00	1883.00
IUUC-Oan-072797	Ornithorhynchus anatinus	79.18	0.00e+00	2027.00
IUUC-Oba-075388	Oryza barthii	27.83	1.00e-82	302.00
IUUC-Obr-076296	Oryza brachyantha	34.43	8.00e-97	350.00
IUUC-Ogu-079040	Oryza glumaepatula	27.88	4.00e-83	303.00
IUUC-Ome-081764	Oryza meridionalis	29.78	3.00e-101	364.00
IUUC-Oni-083012	Oryza nivara	27.78	2.00e-82	301.00
IUUC-Oru-084630	Oryza rufipogon	27.41	6.00e-82	300.00
IUUC-Ola-087076	Oryzias latipes	74.71	0.00e+00	2091.00
IUUC-Oga-088350	Otolemur garnettii	93.20	0.00e+00	2918.00
IUUC-Oar-090045	Ovis aries	94.67	0.00e+00	2982.00
IUUC-Ptr-091199	Pan troglodytes	95.04	0.00e+00	2971.00
IUUC-Pan-092094	Papio anubis	92.87	0.00e+00	2907.00
IUUC-Psi-093550	Pelodiscus sinensis	91.59	0.00e+00	2601.00
IUUC-Pma-094137	Petromyzon marinus	53.02	0.00e+00	1297.00
IUUC-Pno-094879	Phaeosphaeria nodorum	29.58	1.00e-119	424.00
IUUC-Ppa-095839	Physcomitrella patens	35.20	6.00e-16	80.90
IUUC-Pfo-097266	Poecilia formosa	74.95	0.00e+00	2107.00
IUUC-Pab-098576	Pongo abelii	94.92	0.00e+00	3027.00
IUUC-Pca-100123	Procavia capensis	93.44	0.00e+00	1644.00
IUUC-Ppe-101504	Prunus persica	32.57	4.00e-103	370.00
IUUC-Pva-103109	Pteropus vampyrus	88.74	0.00e+00	2838.00
IUUC-Pte-104195	Pyrenophora teres	30.33	4.00e-124	439.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	30.52	1.00e-125	445.00
IUUC-Rno-105664	Rattus norvegicus	93.79	0.00e+00	2941.00
IUUC-Sha-107506	Sarcophilus harrisii	90.75	0.00e+00	2529.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	20.80	4.00e-34	140.00
IUUC-Spo-108283	Schizosaccharomyces pombe	22.32	5.00e-53	203.00
IUUC-Ssl-108489	Sclerotinia sclerotiorum	29.75	5.00e-118	419.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	1.00e-10	62.40
IUUC-Sit-110534	Setaria italica	29.77	5.00e-121	429.00
IUUC-Sar-113052	Sorex araneus	93.42	0.00e+00	2994.00
IUUC-Sbi-114173	Sorghum bicolor	58.14	1.00e-11	64.30
IUUC-Tgu-116613	Taeniopygia guttata	89.04	0.00e+00	2819.00
IUUC-Tru-118604	Takifugu rubripes	75.34	0.00e+00	2148.00
IUUC-Tsy-119237	Tarsius syrichta	97.86	0.00e+00	1310.00
IUUC-Tni-120779	Tetraodon nigroviridis	75.05	0.00e+00	2127.00
IUUC-Tae-125894	Triticum aestivum	29.28	2.00e-110	394.00
IUUC-Tme-127087	Tuber melanosporum	31.22	8.00e-133	469.00
IUUC-Tbe-127627	Tupaia belangeri	97.73	0.00e+00	802.00
IUUC-Ttr-129242	Tursiops truncatus	93.79	0.00e+00	2731.00
IUUC-Uma-129590	Ustilago maydis	30.26	2.00e-133	471.00
IUUC-Vda-129733	Verticillium dahliae	29.13	9.00e-106	379.00
IUUC-Vpa-130429	Vicugna pacos	90.33	0.00e+00	1471.00
IUUC-Xtr-131762	Xenopus tropicalis	75.26	0.00e+00	2259.00
IUUC-Xma-133693	Xiphophorus maculatus	75.05	0.00e+00	2125.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence