iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049847

Ensembl Protein ID

ENSLACP00000004236.1

UniProt Accession

H3A3L5; H3A3L5_LATCH

Genbank Protein ID

ENSLACP00000004236

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01180716

Gene Name

USP7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000003770.1	ENSLACT00000004273.1	ENSLACP00000004236.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-68	231.6	213	519

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 213  VGLKNQGATCYMNSLLQTLFFTNQLRRAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 292
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c++ d +s+r e+ +d++l+++g
   Q: 293  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKG 355
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ ++P+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 356  KK-----NIFESFIDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTFPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 438
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           p+ k+  + +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 439  PDPKD--PANYILHAVLVHSGDNHGGHYVVYLNPkGDGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 519
           **998..*************************9834566************86666664446*******************87 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MNHQQQQHQK PGEQQLSEPE DMEMEAGDTD DPPRITPNPV INGNVAMADG HNNTEEDMED 60
DTSWRSEATF QFTVERFGRL SESVLSPPCF VRNLPWKIMV MPRFYPDRPH QKSVGFFLQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCTCGGTG CCTCAGAGGG GAGAAAAGGA ATATAATACA AGCAAACCGT ATGGCTGTGG 60
GTTCGGATTC GAAATCTAAC GAACTGAGGC GCGGAAACGG CACAAATTAT AGGAAAGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lcm:102352615

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	33.21	6.00e-142	498.00
IUUC-Aml-002408	Ailuropoda melanoleuca	96.47	0.00e+00	2156.00
IUUC-Atr-003067	Amborella trichopoda	37.31	8.00e-124	437.00
IUUC-Apl-003558	Anas platyrhynchos	97.22	0.00e+00	2193.00
IUUC-Aca-004518	Anolis carolinensis	91.34	0.00e+00	2050.00
IUUC-Aly-006427	Arabidopsis lyrata	35.71	7.00e-156	544.00
IUUC-Ath-006591	Arabidopsis thaliana	35.68	3.00e-155	542.00
IUUC-Ago-007849	Ashbya gossypii	31.96	4.00e-139	489.00
IUUC-Acl-008327	Aspergillus clavatus	34.48	7.00e-175	607.00
IUUC-Afl-008491	Aspergillus flavus	35.04	5.00e-169	588.00
IUUC-Afu-008804	Aspergillus fumigatus	35.32	9.00e-167	580.00
IUUC-Ang-009776	Aspergillus niger	35.84	1.00e-165	577.00
IUUC-Aor-009998	Aspergillus oryzae	34.29	8.00e-161	561.00
IUUC-Ate-010428	Aspergillus terreus	35.06	1.00e-168	587.00
IUUC-Ame-010903	Astyanax mexicanus	94.81	0.00e+00	2189.00
IUUC-Bgr-012132	Blumeria graminis	31.98	3.00e-147	516.00
IUUC-Bta-013192	Bos taurus	96.02	0.00e+00	2153.00
IUUC-Bci-013924	Botrytis cinerea	34.49	1.00e-154	540.00
IUUC-Bdi-015069	Brachypodium distachyon	37.33	3.00e-154	539.00
IUUC-Bol-016114	Brassica oleracea	35.92	4.00e-155	542.00
IUUC-Bra-017080	Brassica rapa	36.73	1.00e-157	550.00
IUUC-Cel-018219	Caenorhabditis elegans	34.13	3.00e-157	549.00
IUUC-Cja-019006	Callithrix jacchus	95.18	0.00e+00	2123.00
IUUC-Cfa-020361	Canis familiaris	96.56	0.00e+00	2156.00
IUUC-Cpo-022320	Cavia porcellus	96.01	0.00e+00	2146.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	43.63	1.00e-90	327.00
IUUC-Csa-024050	Chlorocebus sabaeus	96.19	0.00e+00	2182.00
IUUC-Cho-024434	Choloepus hoffmanni	87.48	0.00e+00	1385.00
IUUC-Cin-025689	Ciona intestinalis	54.32	0.00e+00	1222.00
IUUC-Csv-025963	Ciona savignyi	53.67	0.00e+00	1173.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.73	4.00e-154	538.00
IUUC-Cne-026968	Cryptococcus neoformans	36.56	0.00e+00	639.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.07	2.00e-116	414.00
IUUC-Dre-028510	Danio rerio	94.97	0.00e+00	2177.00
IUUC-Dno-029696	Dasypus novemcinctus	96.10	0.00e+00	2141.00
IUUC-Dor-030611	Dipodomys ordii	79.57	0.00e+00	939.00
IUUC-Dse-031433	Dothistroma septosporum	34.05	5.00e-149	522.00
IUUC-Dme-031583	Drosophila melanogaster	48.88	0.00e+00	1040.00
IUUC-Ete-033191	Echinops telfairi	94.24	0.00e+00	2105.00
IUUC-Eca-034122	Equus caballus	96.19	0.00e+00	2149.00
IUUC-Eeu-035292	Erinaceus europaeus	81.88	0.00e+00	666.00
IUUC-Fca-036377	Felis catus	96.47	0.00e+00	2155.00
IUUC-Fal-036964	Ficedula albicollis	97.44	0.00e+00	2155.00
IUUC-Fox-037695	Fusarium oxysporum	33.16	1.00e-163	570.00
IUUC-Fso-038084	Fusarium solani	32.85	1.00e-162	567.00
IUUC-Gmo-038644	Gadus morhua	94.32	0.00e+00	2174.00
IUUC-Ggr-040029	Gaeumannomyces graminis	33.79	3.00e-160	559.00
IUUC-Gga-040944	Gallus gallus	97.44	0.00e+00	2196.00
IUUC-Gac-041740	Gasterosteus aculeatus	94.18	0.00e+00	2183.00
IUUC-Gma-043300	Glycine max	36.73	2.00e-168	586.00
IUUC-Ggo-044947	Gorilla gorilla	96.02	0.00e+00	2154.00
IUUC-Hsa-046278	Homo sapiens	96.01	0.00e+00	2179.00
IUUC-Hvu-047749	Hordeum vulgare	36.79	8.00e-140	491.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	96.46	0.00e+00	1853.00
IUUC-Kpa-049121	Komagataella pastoris	31.03	6.00e-133	468.00
IUUC-Lpe-051505	Leersia perrieri	35.78	1.00e-141	497.00
IUUC-Loc-052234	Lepisosteus oculatus	82.87	0.00e+00	1853.00
IUUC-Lma-053169	Leptosphaeria maculans	37.00	2.00e-171	597.00
IUUC-Laf-053566	Loxodonta africana	96.29	0.00e+00	2153.00
IUUC-Mcc-055549	Macaca mulatta	95.75	0.00e+00	2148.00
IUUC-Meu-056887	Macropus eugenii	86.85	0.00e+00	1253.00
IUUC-Mor-057149	Magnaporthe oryzae	34.60	2.00e-162	566.00
IUUC-Mpo-057536	Magnaporthe poae	33.85	7.00e-161	561.00
IUUC-Mtr-058583	Medicago truncatula	37.65	9.00e-162	564.00
IUUC-Mla-058899	Melampsora laricipopulina	37.56	4.00e-175	608.00
IUUC-Mga-060148	Meleagris gallopavo	97.40	0.00e+00	2199.00
IUUC-Mvi-060207	Microbotryum violaceum	36.92	0.00e+00	639.00
IUUC-Mmr-060946	Microcebus murinus	96.42	0.00e+00	2180.00
IUUC-Mdo-062079	Monodelphis domestica	89.65	0.00e+00	1947.00
IUUC-Mmu-063678	Mus musculus	95.47	0.00e+00	2143.00
IUUC-Mac-065416	Musa acuminata	37.10	2.00e-154	540.00
IUUC-Mpu-066744	Mustela putorius furo	96.30	0.00e+00	2111.00
IUUC-Mlu-067949	Myotis lucifugus	95.73	0.00e+00	2131.00
IUUC-Nfi-068342	Neosartorya fischeri	35.32	2.00e-166	580.00
IUUC-Ncr-068818	Neurospora crassa	33.79	3.00e-166	579.00
IUUC-Nle-070064	Nomascus leucogenys	96.01	0.00e+00	2180.00
IUUC-Opr-071001	Ochotona princeps	94.75	0.00e+00	1782.00
IUUC-Ont-072095	Oreochromis niloticus	94.45	0.00e+00	2179.00
IUUC-Oan-073483	Ornithorhynchus anatinus	97.06	0.00e+00	2114.00
IUUC-Ocu-073967	Oryctolagus cuniculus	95.41	0.00e+00	2065.00
IUUC-Oba-075811	Oryza barthii	34.15	2.00e-139	489.00
IUUC-Obr-076514	Oryza brachyantha	36.50	2.00e-154	540.00
IUUC-Ogl-077038	Oryza glaberrima	35.70	9.00e-150	524.00
IUUC-Ogu-078265	Oryza glumaepatula	34.19	3.00e-136	479.00
IUUC-Oin-079513	Oryza indica	35.23	6.00e-141	495.00
IUUC-Olo-081067	Oryza longistaminata	34.10	6.00e-138	484.00
IUUC-Ome-081879	Oryza meridionalis	36.19	2.00e-150	526.00
IUUC-Oni-082461	Oryza nivara	34.88	3.00e-146	512.00
IUUC-Opu-083199	Oryza punctata	35.62	8.00e-146	511.00
IUUC-Oru-085109	Oryza rufipogon	35.68	7.00e-146	511.00
IUUC-Osa-085418	Oryza sativa	38.87	6.00e-129	455.00
IUUC-Ola-086640	Oryzias latipes	94.09	0.00e+00	2172.00
IUUC-Olu-087874	Ostreococcus lucimarinus	33.77	1.00e-142	500.00
IUUC-Oga-089059	Otolemur garnettii	89.32	0.00e+00	1960.00
IUUC-Oar-089710	Ovis aries	96.29	0.00e+00	2154.00
IUUC-Ptr-091334	Pan troglodytes	96.02	0.00e+00	2154.00
IUUC-Pan-091717	Papio anubis	96.55	0.00e+00	2090.00
IUUC-Psi-093933	Pelodiscus sinensis	96.84	0.00e+00	2223.00
IUUC-Pma-094648	Petromyzon marinus	84.34	0.00e+00	1745.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.93	1.00e-155	543.00
IUUC-Ppa-096020	Physcomitrella patens	34.99	8.00e-165	574.00
IUUC-Pfo-096181	Poecilia formosa	94.24	0.00e+00	2165.00
IUUC-Pab-098231	Pongo abelii	93.52	0.00e+00	2080.00
IUUC-Pop-099680	Populus trichocarpa	37.13	1.00e-159	557.00
IUUC-Pca-100543	Procavia capensis	80.06	0.00e+00	998.00
IUUC-Ppe-101523	Prunus persica	36.04	3.00e-152	533.00
IUUC-Pva-102472	Pteropus vampyrus	95.26	0.00e+00	2106.00
IUUC-Pgr-103463	Puccinia graminis	36.52	3.00e-175	609.00
IUUC-Ptt-103716	Puccinia triticina	38.33	1.00e-171	597.00
IUUC-Pte-104360	Pyrenophora teres	36.89	4.00e-157	549.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	36.51	2.00e-155	543.00
IUUC-Rno-105816	Rattus norvegicus	95.56	0.00e+00	2173.00
IUUC-Sce-106230	Saccharomyces cerevisiae	38.69	7.00e-119	422.00
IUUC-Sha-107439	Sarcophilus harrisii	97.12	0.00e+00	2157.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	33.39	5.00e-142	498.00
IUUC-Spo-108019	Schizosaccharomyces pombe	34.27	2.00e-144	507.00
IUUC-Smo-109308	Selaginella moellendorffii	35.91	5.00e-153	535.00
IUUC-Sit-110367	Setaria italica	36.25	7.00e-157	548.00
IUUC-Sly-111337	Solanum lycopersicum	37.92	4.00e-162	565.00
IUUC-Stu-112387	Solanum tuberosum	36.50	9.00e-163	567.00
IUUC-Sar-113685	Sorex araneus	95.36	0.00e+00	2126.00
IUUC-Sbi-114037	Sorghum bicolor	36.95	3.00e-155	542.00
IUUC-Sre-115156	Sporisorium reilianum	38.70	0.00e+00	648.00
IUUC-Ssc-116297	Sus scrofa	96.19	0.00e+00	2185.00
IUUC-Tgu-116767	Taeniopygia guttata	97.26	0.00e+00	2225.00
IUUC-Tru-118208	Takifugu rubripes	94.14	0.00e+00	2144.00
IUUC-Tsy-119277	Tarsius syrichta	83.53	0.00e+00	697.00
IUUC-Tni-119890	Tetraodon nigroviridis	94.05	0.00e+00	2147.00
IUUC-Tca-121501	Theobroma cacao	36.09	2.00e-156	546.00
IUUC-Tre-122169	Trichoderma reesei	33.70	2.00e-154	540.00
IUUC-Tvi-122600	Trichoderma virens	34.15	2.00e-162	566.00
IUUC-Tae-125264	Triticum aestivum	35.41	2.00e-152	533.00
IUUC-Tur-126287	Triticum urartu	35.30	1.00e-149	524.00
IUUC-Tme-127045	Tuber melanosporum	35.10	1.00e-170	593.00
IUUC-Tbe-127696	Tupaia belangeri	85.34	3.00e-153	535.00
IUUC-Ttr-129161	Tursiops truncatus	96.38	0.00e+00	2147.00
IUUC-Uma-129535	Ustilago maydis	38.55	0.00e+00	662.00
IUUC-Vda-129708	Verticillium dahliae	33.64	2.00e-162	566.00
IUUC-Vvi-131048	Vitis vinifera	35.70	4.00e-156	545.00
IUUC-Xtr-132073	Xenopus tropicalis	93.03	0.00e+00	2105.00
IUUC-Xma-133949	Xiphophorus maculatus	93.96	0.00e+00	2159.00
IUUC-Yli-134527	Yarrowia lipolytica	33.22	1.00e-138	488.00
IUUC-Zma-135855	Zea mays	36.47	6.00e-146	511.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence