iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089053

Ensembl Protein ID

ENSOGAP00000012190.2

UniProt Accession

H0X9F7; H0X9F7_OTOGA

Genbank Protein ID

ENSOGAP00000012190

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03187516

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000013597.2	ENSOGAT00000013608.2	ENSOGAP00000012190.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.60e-29	99.0	178	215
UBD/Beta-Prp	1.40e-51	175.5	280	539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll
   Q: 178  GHLSSVYCVAFdrSGRRIFTGSDDCLVKIWATDDGRLL 215
           8**********96669******************9987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheae..vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvl 98
           +++l+++++dgti  w+++ +++        + + s    +  +++ +fs+ g ++ tgs+D++i+++    + ++ +  l+ h+d+v+
   Q: 280  TRYLTSTGADGTICFWQWHVKTMkfrdrpvkFTERSRP--GvqISCSSFSSGGMFITTGSTDHVIRLYylGSEIPEKIAELESHTDKVV 366
           689*************9998777667776433333333..35599***********************7777899************** PP
   S: 99   slsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
           +++f+ +g   ++vsGs+d t+r+w+ +++++ +                  +++++  v++v+++  +  + ++ ++  +++W++ tg
   Q: 367  AVQFCNNGdsLRFVSGSRDGTARIWQYQQQEWKSIvldmatkmtgnnlpsgEDKVTKLKVTMVAWDRYDTTVTTAVNNFLLKVWNSITG 455
           ******8832468*******************999************999888888889****************************** PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           +ll+tl+g h+d v  l+   fd+  + ++s+++dg + +wdl +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 456  QLLHTLSG-HDDEVFVLEahpFDQ--RIILSAGHDGNIFIWDLDRGTKIRNYFNMIegqghGAVFDCKFSPDGNHFACTDSHGHLLL 539
           *******9.*********555555..99********************98887755455567788899999*999999999988765 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAAAPTQIEA ELYYLIARFL QSGPCNKSAQ VLVQELEEHQ LIPRRLDWEG KEHRRSFEDL 60
VAANAHIPPD YLLKICERIG PLLDKEIPQS VPGVQTLLGV GRQSLLRDAK DYKSTLWNGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCAAACC CCCTCGGGAA AAGGATGGCG GCGGCACCTA CCCAGATCGA AGCCGGTGGG 60
TAGCTGTGTC CGGGGAGCTA AGGGTGTGTG TGGGGGGGTG GGGGGGTAGC GCGACTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.28	2.00e-58	222.00
IUUC-Aml-001881	Ailuropoda melanoleuca	96.17	0.00e+00	3125.00
IUUC-Atr-002600	Amborella trichopoda	29.01	2.00e-65	245.00
IUUC-Apl-004016	Anas platyrhynchos	80.31	0.00e+00	2276.00
IUUC-Aca-004722	Anolis carolinensis	78.16	0.00e+00	2210.00
IUUC-Ath-006577	Arabidopsis thaliana	29.41	4.00e-66	247.00
IUUC-Ame-010602	Astyanax mexicanus	76.21	0.00e+00	1140.00
IUUC-Bta-013198	Bos taurus	94.99	0.00e+00	2858.00
IUUC-Cfa-020963	Canis familiaris	95.89	0.00e+00	3114.00
IUUC-Cpo-022448	Cavia porcellus	88.40	0.00e+00	2819.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	33.45	3.00e-32	134.00
IUUC-Csa-023166	Chlorocebus sabaeus	95.24	0.00e+00	2973.00
IUUC-Cin-025553	Ciona intestinalis	38.90	3.00e-112	399.00
IUUC-Csv-025813	Ciona savignyi	43.95	0.00e+00	644.00
IUUC-Dre-028508	Danio rerio	66.16	0.00e+00	1889.00
IUUC-Dno-030070	Dasypus novemcinctus	92.46	0.00e+00	2991.00
IUUC-Dor-031052	Dipodomys ordii	82.54	0.00e+00	1338.00
IUUC-Dme-031752	Drosophila melanogaster	49.13	0.00e+00	669.00
IUUC-Ete-032650	Echinops telfairi	85.73	0.00e+00	1835.00
IUUC-Eca-033953	Equus caballus	96.13	0.00e+00	2809.00
IUUC-Eeu-034871	Erinaceus europaeus	82.23	0.00e+00	1340.00
IUUC-Fca-036099	Felis catus	95.84	0.00e+00	3140.00
IUUC-Fal-037246	Ficedula albicollis	81.06	0.00e+00	2443.00
IUUC-Gga-041097	Gallus gallus	83.24	0.00e+00	2540.00
IUUC-Gac-042435	Gasterosteus aculeatus	65.29	0.00e+00	1843.00
IUUC-Hsa-045666	Homo sapiens	95.18	0.00e+00	2972.00
IUUC-Lpe-051619	Leersia perrieri	29.48	5.00e-64	240.00
IUUC-Loc-051802	Lepisosteus oculatus	70.10	0.00e+00	2079.00
IUUC-Laf-053942	Loxodonta africana	95.48	0.00e+00	3008.00
IUUC-Mcc-054645	Macaca mulatta	95.36	0.00e+00	2979.00
IUUC-Meu-056321	Macropus eugenii	76.51	0.00e+00	1117.00
IUUC-Mtr-058094	Medicago truncatula	30.42	6.00e-67	250.00
IUUC-Mga-060063	Meleagris gallopavo	82.97	0.00e+00	2481.00
IUUC-Mmr-061262	Microcebus murinus	95.90	0.00e+00	3001.00
IUUC-Mdo-062320	Monodelphis domestica	75.54	0.00e+00	2296.00
IUUC-Mmu-063163	Mus musculus	93.56	0.00e+00	3028.00
IUUC-Mac-065343	Musa acuminata	29.31	2.00e-66	248.00
IUUC-Mpu-066628	Mustela putorius furo	95.72	0.00e+00	3147.00
IUUC-Mlu-068082	Myotis lucifugus	95.66	0.00e+00	2959.00
IUUC-Nle-069609	Nomascus leucogenys	95.24	0.00e+00	2992.00
IUUC-Ont-071589	Oreochromis niloticus	66.28	0.00e+00	1820.00
IUUC-Ocu-074122	Oryctolagus cuniculus	94.54	0.00e+00	2127.00
IUUC-Oba-075709	Oryza barthii	28.49	2.00e-57	218.00
IUUC-Obr-076619	Oryza brachyantha	29.60	2.00e-65	245.00
IUUC-Opu-083233	Oryza punctata	28.88	2.00e-59	225.00
IUUC-Oru-085195	Oryza rufipogon	28.49	2.00e-57	218.00
IUUC-Ola-086580	Oryzias latipes	66.25	0.00e+00	1878.00
IUUC-Oar-090042	Ovis aries	95.50	0.00e+00	3133.00
IUUC-Ptr-091268	Pan troglodytes	94.28	0.00e+00	2925.00
IUUC-Pan-092376	Papio anubis	95.30	0.00e+00	2978.00
IUUC-Psi-093408	Pelodiscus sinensis	81.68	0.00e+00	2521.00
IUUC-Pma-094427	Petromyzon marinus	65.31	2.00e-130	458.00
IUUC-Ppa-095793	Physcomitrella patens	28.74	2.00e-68	255.00
IUUC-Pfo-096515	Poecilia formosa	64.73	0.00e+00	1778.00
IUUC-Pab-097672	Pongo abelii	93.67	0.00e+00	2951.00
IUUC-Ppe-101849	Prunus persica	30.58	7.00e-67	249.00
IUUC-Pva-102512	Pteropus vampyrus	96.91	0.00e+00	2349.00
IUUC-Rno-105797	Rattus norvegicus	93.49	0.00e+00	2913.00
IUUC-Sha-107061	Sarcophilus harrisii	76.61	0.00e+00	2313.00
IUUC-Sit-110017	Setaria italica	29.00	1.00e-55	212.00
IUUC-Sly-111348	Solanum lycopersicum	29.17	1.00e-66	249.00
IUUC-Sar-113004	Sorex araneus	82.77	0.00e+00	1652.00
IUUC-Sbi-114195	Sorghum bicolor	29.27	8.00e-55	208.00
IUUC-Tgu-117254	Taeniopygia guttata	81.73	0.00e+00	2436.00
IUUC-Tru-118186	Takifugu rubripes	65.38	0.00e+00	1828.00
IUUC-Tsy-119003	Tarsius syrichta	89.67	0.00e+00	2728.00
IUUC-Tni-120110	Tetraodon nigroviridis	65.25	0.00e+00	1800.00
IUUC-Tca-121615	Theobroma cacao	29.61	1.00e-61	232.00
IUUC-Tae-125478	Triticum aestivum	30.79	7.00e-68	253.00
IUUC-Tur-126809	Triticum urartu	30.63	4.00e-65	244.00
IUUC-Tbe-127813	Tupaia belangeri	76.48	0.00e+00	928.00
IUUC-Ttr-129265	Tursiops truncatus	92.59	0.00e+00	2852.00
IUUC-Vpa-130736	Vicugna pacos	88.64	0.00e+00	1490.00
IUUC-Vvi-131362	Vitis vinifera	28.86	1.00e-66	249.00
IUUC-Xma-134159	Xiphophorus maculatus	66.53	0.00e+00	1754.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence