iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096503

Ensembl Protein ID

ENSPFOP00000013290.2

UniProt Accession

A0A087Y5I7; A0A087Y5I7_POEFO

Genbank Protein ID

ENSPFOP00000013290

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01004767

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000013121.2	ENSPFOT00000013308.2	ENSPFOP00000013290.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.30e-84	282.1	314	923
UBD/Alpha-Helix/UIM	4.80e-08	32.7	780	797

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +G++NlgNtCYmN++LQ+L+++p++ +++l+   +++ ++  k p ++ll+ +++l+ +      ++k+   r++++a++++ae+fsg+
   Q: 314  QGFSNLGNTCYMNAILQSLFSLPSFSNDMLK---QSITWK--KVPVNALLRRFAHLMVKKDvaCPETKKDLLRKVKNAISSTAERFSGN 397
           69*****************************...999998..46888888888888876656688899999****************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde............aeekkkkknkslisdlFqgqlksqikclecdnvss 164
            q+Da+Efl+++ldql+++++k +++   ++  ++  ++s               e ++ + +++++  +++++++++i+c+ c++v +
   Q: 398  VQNDAHEFLSQCLDQLKDDVEKMNKSLAIDTAASS--SSSVTcdnppeavatpgDEADTSRIYTCPVAVNMEFEVQHTITCKCCGEVVN 484
           ********************663333333332222..222225578999999988889999999************************* PP
   S: 165  reepfldlslpvpgkeetkke.slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
           ++e+f+dls+++p++++t ++ s+qd+L+ f++ ee+e    y+cekc +k+ a+ ++k++klP+vLilhLkR+sf+ + + ++k+ ++
   Q: 485  KREQFNDLSIDLPRRKKTLPLrSIQDSLDLFFRMEEIE----YSCEKCSGKS-ATVTHKFSKLPRVLILHLKRYSFNAQLSLNSKLGQQ 568
           *************999887645***************9....********99.9*********************************** PP
   S: 253  vefpleLdlspfcts.......................................................................... 267
           v +p+ L+l ++ct+                                                                          
   Q: 569  VLIPRYLTLLSHCTDgtrppvslswtpqpatsrtlktsqsinssttpqrrvggkssscssvlldsdyedeptrkvnvsrrrrlsvclpe 657
           ************************************99999999999999999999999999999999999999999999999999999 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 658  eddrpeekpaaaamdstefgginddemlaavlemsreeaglpaaapledeptsspdtgfgdsdvhdlayhtelletdskqpadvldsld 746
           88888888888888888888888888888888888888888888888888888888888888888888888887777777777777777 PP
   S: 268  ..............................peekqke.................................................... 274
                                         +     e                                                    
   Q: 747  ltmdenkenqtpegvqpqgeldwvqqynldQ-----Ereeqelqqalaqslqeheaqemredddlkratelslqefnnslpellgsddd 830
           7776666666655555555555555555550.....05555566666666666667777777777777788888888888888888888 PP
   S: 275  ............................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvl 333
                                        ++Y+Li+vv+H G s+ssGHY+++v++ k++ Wl+++D  V+ ++e+ v++++++++Y++
   Q: 831  sgnedvldmeyteaeaetlkrnaeagelANSYRLISVVSHIGsSSSSGHYISDVYDMKKQsWLTYNDLDVSRTQEAAVQRDRDRSGYIF 919
           8888888888888888999999999999****************************88888**************************** PP
   S: 334  fYkr 337
           fY++
   Q: 920  FYMH 923
           **98 PP

UBD/Alpha-Helix/UIM

   S: 2    EdeeLqlAlalSlqEeee 19
           E++eLq+Ala+SlqE+e 
   Q: 780  EEQELQQALAQSLQEHEA 797
           9***************95 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MAALGPKLSS GGTVKIRFNS MDLGTTKWKE GTFEILEKDN KVSLSLRYSS GGAARTFQLN 60
QNVKSFTQNL NRIMLTLKDN SVITLDKMPA QLVQRTKEYL EKLKQGKSVL KSSHGSANFG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAGAAATTC ATACCACATG AAGCGAAATG ACATGGATCC CGGAAGAGAG CCGAAAGTCC 60
CATCACCATC TCCTTTCCGT TGTAAACGTT CACATTCCCG CCATCATCGC GCGTTGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001400	Ailuropoda melanoleuca	55.89	0.00e+00	921.00
IUUC-Apl-004033	Anas platyrhynchos	55.58	0.00e+00	922.00
IUUC-Aca-005370	Anolis carolinensis	54.65	0.00e+00	889.00
IUUC-Ame-011884	Astyanax mexicanus	71.01	0.00e+00	1239.00
IUUC-Bta-012725	Bos taurus	55.97	0.00e+00	902.00
IUUC-Cja-019939	Callithrix jacchus	55.76	0.00e+00	900.00
IUUC-Cfa-020835	Canis familiaris	56.69	0.00e+00	941.00
IUUC-Cpo-022067	Cavia porcellus	54.85	0.00e+00	835.00
IUUC-Cre-022867	Chlamydomonas reinhardtii	31.27	5.00e-26	113.00
IUUC-Csa-023085	Chlorocebus sabaeus	55.74	0.00e+00	919.00
IUUC-Cho-024390	Choloepus hoffmanni	54.52	3.00e-64	240.00
IUUC-Cin-025496	Ciona intestinalis	37.69	1.00e-46	181.00
IUUC-Csv-025812	Ciona savignyi	35.79	3.00e-42	166.00
IUUC-Dre-028255	Danio rerio	70.93	0.00e+00	1215.00
IUUC-Dno-028986	Dasypus novemcinctus	55.40	0.00e+00	902.00
IUUC-Dor-031062	Dipodomys ordii	44.03	7.00e-123	435.00
IUUC-Ete-032359	Echinops telfairi	49.40	2.00e-122	434.00
IUUC-Eca-033964	Equus caballus	55.41	0.00e+00	919.00
IUUC-Eeu-034492	Erinaceus europaeus	53.53	2.00e-121	431.00
IUUC-Fca-036359	Felis catus	55.49	0.00e+00	917.00
IUUC-Fal-037640	Ficedula albicollis	56.31	0.00e+00	905.00
IUUC-Gmo-039600	Gadus morhua	75.88	0.00e+00	1345.00
IUUC-Gga-040126	Gallus gallus	55.12	0.00e+00	872.00
IUUC-Gac-041557	Gasterosteus aculeatus	79.57	0.00e+00	1395.00
IUUC-Ggo-045571	Gorilla gorilla	53.41	0.00e+00	789.00
IUUC-Hsa-046043	Homo sapiens	55.67	0.00e+00	904.00
IUUC-Itr-048207	Ictidomys tridecemlineatus	56.05	0.00e+00	900.00
IUUC-Lch-050357	Latimeria chalumnae	53.78	0.00e+00	781.00
IUUC-Loc-052849	Lepisosteus oculatus	69.48	0.00e+00	1139.00
IUUC-Laf-054570	Loxodonta africana	55.38	0.00e+00	878.00
IUUC-Mcc-054989	Macaca mulatta	53.80	0.00e+00	832.00
IUUC-Meu-056273	Macropus eugenii	36.67	9.00e-74	272.00
IUUC-Mga-059814	Meleagris gallopavo	53.56	0.00e+00	859.00
IUUC-Mmr-061726	Microcebus murinus	55.78	0.00e+00	910.00
IUUC-Mdo-062974	Monodelphis domestica	56.73	0.00e+00	935.00
IUUC-Mmu-064069	Mus musculus	56.09	0.00e+00	900.00
IUUC-Mpu-066008	Mustela putorius furo	55.74	0.00e+00	914.00
IUUC-Mlu-068224	Myotis lucifugus	33.58	3.00e-105	376.00
IUUC-Nle-069259	Nomascus leucogenys	55.66	0.00e+00	906.00
IUUC-Opr-070882	Ochotona princeps	54.62	3.00e-92	333.00
IUUC-Ont-072441	Oreochromis niloticus	84.81	0.00e+00	1503.00
IUUC-Oan-073151	Ornithorhynchus anatinus	59.56	1.00e-87	316.00
IUUC-Ocu-074879	Oryctolagus cuniculus	55.84	0.00e+00	900.00
IUUC-Ola-087007	Oryzias latipes	78.20	0.00e+00	1315.00
IUUC-Oga-088385	Otolemur garnettii	55.07	0.00e+00	908.00
IUUC-Oar-090305	Ovis aries	55.43	0.00e+00	919.00
IUUC-Ptr-091299	Pan troglodytes	55.67	0.00e+00	904.00
IUUC-Pan-091996	Papio anubis	55.84	0.00e+00	904.00
IUUC-Psi-093176	Pelodiscus sinensis	56.41	0.00e+00	925.00
IUUC-Pma-094331	Petromyzon marinus	44.26	0.00e+00	640.00
IUUC-Pab-098543	Pongo abelii	59.74	3.00e-151	529.00
IUUC-Pca-101099	Procavia capensis	55.30	0.00e+00	719.00
IUUC-Pva-103163	Pteropus vampyrus	53.15	6.00e-176	611.00
IUUC-Rno-105766	Rattus norvegicus	55.62	0.00e+00	888.00
IUUC-Sha-106610	Sarcophilus harrisii	55.09	0.00e+00	837.00
IUUC-Sar-113624	Sorex araneus	43.44	5.00e-54	206.00
IUUC-Ssc-116353	Sus scrofa	56.10	0.00e+00	891.00
IUUC-Tgu-116971	Taeniopygia guttata	56.31	0.00e+00	883.00
IUUC-Tru-117932	Takifugu rubripes	56.12	0.00e+00	898.00
IUUC-Tsy-119185	Tarsius syrichta	54.40	4.00e-179	622.00
IUUC-Tni-119842	Tetraodon nigroviridis	70.03	2.00e-131	463.00
IUUC-Tbe-127281	Tupaia belangeri	42.58	1.00e-76	281.00
IUUC-Ttr-128177	Tursiops truncatus	60.24	0.00e+00	775.00
IUUC-Vpa-130031	Vicugna pacos	55.98	0.00e+00	918.00
IUUC-Xtr-132949	Xenopus tropicalis	54.25	0.00e+00	867.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence