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Tag Content
UUCD2 ID IUUC-Xtr-132633
UUCD1 version UUC-XeT-00574
Ensembl Protein ID ENSXETP00000062014.1
UniProt Accession F7A7Q0; F7A7Q0_XENTR
Genbank Protein ID ENSXETP00000062014
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID AAMC01022146
Gene Name copb2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000008250.3 ENSXETT00000061296.1 ENSXETP00000062014.1
ENSXETG00000008250.3 ENSXETT00000018095.3 ENSXETP00000018095.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.90e-34 115.8 183 224
UBD/Beta-Prp 1.80e-72 244.2 13 292
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ vtg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDY 101
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+++++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++v+
   Q: 190  CIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVS 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlgse 285
           +l+ ++nv +  +e
   Q: 279  GLRGSNNVALGYDE 292
           *9999998754444 PP
   
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RAAKFVARKN WVVTGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPFILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132633|E3,WD_repeat;UBD,Beta-Prp|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGGGACCGA AGAACCGGGG AAATGGTGAG TAAGGCTGTT GAAGGATTAG TATTATAGGT 60
TTATTAAACA ACTGGGGCGA CGGTAATCAT AAATGCATGG TTGTCAGAAG TTGGAAATAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132633|E3,WD_repeat;UBD,Beta-Prp|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER
GO:0061053--P:somite development
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 53.16 0.00e+00 942.00
IUUC-Aml-002154 Ailuropoda melanoleuca 88.68 0.00e+00 1689.00
IUUC-Atr-003090 Amborella trichopoda 58.75 0.00e+00 1075.00
IUUC-Apl-003976 Anas platyrhynchos 92.68 0.00e+00 1692.00
IUUC-Aca-004301 Anolis carolinensis 92.69 0.00e+00 1694.00
IUUC-Aly-006508 Arabidopsis lyrata 60.90 0.00e+00 1088.00
IUUC-Ath-007630 Arabidopsis thaliana 61.45 0.00e+00 1100.00
IUUC-Ago-007914 Ashbya gossypii 45.95 0.00e+00 753.00
IUUC-Acl-008237 Aspergillus clavatus 56.74 0.00e+00 966.00
IUUC-Afl-008535 Aspergillus flavus 55.70 0.00e+00 912.00
IUUC-Afu-008845 Aspergillus fumigatus 56.48 0.00e+00 941.00
IUUC-Ani-009135 Aspergillus nidulans 56.48 0.00e+00 924.00
IUUC-Ang-009654 Aspergillus niger 55.75 0.00e+00 859.00
IUUC-Aor-009939 Aspergillus oryzae 54.95 0.00e+00 969.00
IUUC-Ate-010355 Aspergillus terreus 54.39 0.00e+00 916.00
IUUC-Ame-010922 Astyanax mexicanus 84.48 0.00e+00 1472.00
IUUC-Bgr-012249 Blumeria graminis 54.83 0.00e+00 926.00
IUUC-Bta-013579 Bos taurus 96.77 0.00e+00 1458.00
IUUC-Bci-013866 Botrytis cinerea 55.96 0.00e+00 922.00
IUUC-Bdi-015046 Brachypodium distachyon 62.42 0.00e+00 1109.00
IUUC-Bol-016271 Brassica oleracea 61.26 0.00e+00 1105.00
IUUC-Bra-016617 Brassica rapa 61.09 0.00e+00 1070.00
IUUC-Cel-018387 Caenorhabditis elegans 66.15 0.00e+00 1192.00
IUUC-Cja-019145 Callithrix jacchus 89.78 0.00e+00 1688.00
IUUC-Cfa-020564 Canis familiaris 94.34 0.00e+00 1687.00
IUUC-Cpo-022201 Cavia porcellus 91.91 0.00e+00 1685.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 59.27 0.00e+00 992.00
IUUC-Csa-023383 Chlorocebus sabaeus 96.47 0.00e+00 1165.00
IUUC-Cho-024454 Choloepus hoffmanni 90.07 0.00e+00 1382.00
IUUC-Cin-025681 Ciona intestinalis 76.36 0.00e+00 1363.00
IUUC-Csv-026012 Ciona savignyi 77.78 0.00e+00 1342.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 51.32 0.00e+00 841.00
IUUC-Cne-026986 Cryptococcus neoformans 51.45 0.00e+00 915.00
IUUC-Cme-027219 Cyanidioschyzon merolae 48.38 0.00e+00 849.00
IUUC-Dre-027846 Danio rerio 92.78 0.00e+00 1659.00
IUUC-Dor-030462 Dipodomys ordii 90.98 0.00e+00 1255.00
IUUC-Dse-031268 Dothistroma septosporum 55.68 0.00e+00 954.00
IUUC-Dme-031791 Drosophila melanogaster 72.27 0.00e+00 1271.00
IUUC-Ete-033166 Echinops telfairi 86.74 0.00e+00 1001.00
IUUC-Eca-034180 Equus caballus 91.75 0.00e+00 1629.00
IUUC-Eeu-035086 Erinaceus europaeus 76.04 0.00e+00 792.00
IUUC-Fca-036265 Felis catus 89.57 0.00e+00 1692.00
IUUC-Fal-037202 Ficedula albicollis 92.35 0.00e+00 1635.00
IUUC-Fox-037711 Fusarium oxysporum 56.66 0.00e+00 880.00
IUUC-Fso-038268 Fusarium solani 55.80 0.00e+00 875.00
IUUC-Gmo-039046 Gadus morhua 92.18 0.00e+00 1647.00
IUUC-Ggr-039863 Gaeumannomyces graminis 55.67 0.00e+00 901.00
IUUC-Gga-041112 Gallus gallus 93.13 0.00e+00 1698.00
IUUC-Gac-041733 Gasterosteus aculeatus 91.23 0.00e+00 1603.00
IUUC-Gma-042910 Glycine max 61.10 0.00e+00 1119.00
IUUC-Ggo-044984 Gorilla gorilla 89.46 0.00e+00 1683.00
IUUC-Hsa-046698 Homo sapiens 89.46 0.00e+00 1682.00
IUUC-Hvu-047669 Hordeum vulgare 71.47 3.00e-169 587.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 89.55 0.00e+00 1685.00
IUUC-Kpa-049265 Komagataella pastoris 49.44 0.00e+00 863.00
IUUC-Lch-050473 Latimeria chalumnae 90.21 0.00e+00 1702.00
IUUC-Lpe-051579 Leersia perrieri 62.35 0.00e+00 1099.00
IUUC-Loc-052675 Lepisosteus oculatus 92.48 0.00e+00 1674.00
IUUC-Lma-053218 Leptosphaeria maculans 54.71 0.00e+00 922.00
IUUC-Laf-053757 Loxodonta africana 89.03 0.00e+00 1673.00
IUUC-Mcc-054859 Macaca mulatta 89.78 0.00e+00 1687.00
IUUC-Meu-056174 Macropus eugenii 90.21 0.00e+00 703.00
IUUC-Mor-057264 Magnaporthe oryzae 57.05 0.00e+00 889.00
IUUC-Mpo-057538 Magnaporthe poae 56.04 0.00e+00 915.00
IUUC-Mtr-058310 Medicago truncatula 62.35 0.00e+00 1123.00
IUUC-Mla-058937 Melampsora laricipopulina 54.21 0.00e+00 915.00
IUUC-Mga-059875 Meleagris gallopavo 93.03 0.00e+00 1694.00
IUUC-Mvi-060240 Microbotryum violaceum 50.93 0.00e+00 910.00
IUUC-Mmr-061261 Microcebus murinus 90.00 0.00e+00 1692.00
IUUC-Mdo-062076 Monodelphis domestica 91.87 0.00e+00 1696.00
IUUC-Mmu-063324 Mus musculus 89.78 0.00e+00 1688.00
IUUC-Mac-064636 Musa acuminata 59.65 0.00e+00 1090.00
IUUC-Mpu-065961 Mustela putorius furo 89.57 0.00e+00 1687.00
IUUC-Mlu-067059 Myotis lucifugus 91.54 0.00e+00 1639.00
IUUC-Nfi-068277 Neosartorya fischeri 56.19 0.00e+00 929.00
IUUC-Ncr-068659 Neurospora crassa 53.11 0.00e+00 909.00
IUUC-Nle-069034 Nomascus leucogenys 89.67 0.00e+00 1688.00
IUUC-Opr-070334 Ochotona princeps 96.19 0.00e+00 1493.00
IUUC-Ont-071563 Oreochromis niloticus 88.14 0.00e+00 1664.00
IUUC-Oan-073416 Ornithorhynchus anatinus 95.47 0.00e+00 1620.00
IUUC-Ocu-074522 Oryctolagus cuniculus 89.57 0.00e+00 1682.00
IUUC-Oba-075760 Oryza barthii 60.05 0.00e+00 1073.00
IUUC-Obr-076163 Oryza brachyantha 62.35 0.00e+00 1104.00
IUUC-Ogl-077450 Oryza glaberrima 61.26 0.00e+00 1100.00
IUUC-Ogu-078994 Oryza glumaepatula 60.05 0.00e+00 1071.00
IUUC-Oin-079856 Oryza indica 59.24 0.00e+00 1082.00
IUUC-Olo-080731 Oryza longistaminata 59.47 0.00e+00 1060.00
IUUC-Ome-081554 Oryza meridionalis 58.11 0.00e+00 1004.00
IUUC-Oni-082324 Oryza nivara 60.05 0.00e+00 1072.00
IUUC-Opu-083400 Oryza punctata 57.59 0.00e+00 1070.00
IUUC-Oru-084829 Oryza rufipogon 60.05 0.00e+00 1071.00
IUUC-Osa-086026 Oryza sativa 61.26 0.00e+00 1103.00
IUUC-Ola-087245 Oryzias latipes 87.27 0.00e+00 1656.00
IUUC-Olu-087655 Ostreococcus lucimarinus 60.30 0.00e+00 1060.00
IUUC-Oga-088163 Otolemur garnettii 86.54 0.00e+00 1614.00
IUUC-Oar-089842 Ovis aries 94.10 0.00e+00 1685.00
IUUC-Ptr-090501 Pan troglodytes 89.78 0.00e+00 1685.00
IUUC-Pan-092011 Papio anubis 89.78 0.00e+00 1687.00
IUUC-Psi-093308 Pelodiscus sinensis 94.91 0.00e+00 1687.00
IUUC-Pma-094695 Petromyzon marinus 80.32 0.00e+00 1440.00
IUUC-Pno-094785 Phaeosphaeria nodorum 62.07 8.00e-112 397.00
IUUC-Ppa-095911 Physcomitrella patens 60.65 0.00e+00 1128.00
IUUC-Pfo-096587 Poecilia formosa 86.20 0.00e+00 1672.00
IUUC-Pab-097926 Pongo abelii 87.35 0.00e+00 1597.00
IUUC-Pop-099634 Populus trichocarpa 61.59 0.00e+00 1102.00
IUUC-Pca-100965 Procavia capensis 90.67 0.00e+00 1638.00
IUUC-Ppe-101470 Prunus persica 62.47 0.00e+00 1119.00
IUUC-Pva-102451 Pteropus vampyrus 90.38 0.00e+00 1250.00
IUUC-Pgr-103453 Puccinia graminis 54.81 0.00e+00 934.00
IUUC-Ptt-103868 Puccinia triticina 55.17 0.00e+00 934.00
IUUC-Pte-104274 Pyrenophora teres 56.05 0.00e+00 953.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 54.72 0.00e+00 900.00
IUUC-Rno-105979 Rattus norvegicus 82.63 0.00e+00 1243.00
IUUC-Sce-106269 Saccharomyces cerevisiae 45.42 0.00e+00 777.00
IUUC-Sha-106905 Sarcophilus harrisii 93.17 0.00e+00 1693.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 47.72 0.00e+00 834.00
IUUC-Spo-108299 Schizosaccharomyces pombe 47.41 0.00e+00 832.00
IUUC-Smo-108695 Selaginella moellendorffii 61.47 0.00e+00 1073.00
IUUC-Sit-110692 Setaria italica 63.32 0.00e+00 1105.00
IUUC-Sly-111775 Solanum lycopersicum 58.49 0.00e+00 1095.00
IUUC-Stu-112906 Solanum tuberosum 59.37 0.00e+00 986.00
IUUC-Sar-113472 Sorex araneus 89.16 0.00e+00 1141.00
IUUC-Sbi-113801 Sorghum bicolor 62.95 0.00e+00 1110.00
IUUC-Sre-115040 Sporisorium reilianum 52.39 0.00e+00 914.00
IUUC-Ssc-115593 Sus scrofa 89.89 0.00e+00 1689.00
IUUC-Tgu-117239 Taeniopygia guttata 92.82 0.00e+00 1698.00
IUUC-Tru-118025 Takifugu rubripes 91.71 0.00e+00 1655.00
IUUC-Tsy-118824 Tarsius syrichta 88.69 0.00e+00 1151.00
IUUC-Tni-120142 Tetraodon nigroviridis 90.06 0.00e+00 1645.00
IUUC-Tca-121613 Theobroma cacao 61.74 0.00e+00 1112.00
IUUC-Tre-122072 Trichoderma reesei 55.24 0.00e+00 926.00
IUUC-Tvi-122546 Trichoderma virens 54.86 0.00e+00 913.00
IUUC-Tae-125321 Triticum aestivum 61.68 0.00e+00 1098.00
IUUC-Tur-126283 Triticum urartu 54.01 0.00e+00 941.00
IUUC-Tme-127041 Tuber melanosporum 55.92 0.00e+00 966.00
IUUC-Tbe-127770 Tupaia belangeri 90.66 0.00e+00 1255.00
IUUC-Ttr-129294 Tursiops truncatus 89.89 0.00e+00 1691.00
IUUC-Uma-129351 Ustilago maydis 50.85 0.00e+00 907.00
IUUC-Vda-129716 Verticillium dahliae 55.49 0.00e+00 945.00
IUUC-Vpa-130037 Vicugna pacos 77.42 0.00e+00 827.00
IUUC-Vvi-131689 Vitis vinifera 60.92 0.00e+00 1107.00
IUUC-Xma-133347 Xiphophorus maculatus 88.34 0.00e+00 1681.00
IUUC-Yli-134455 Yarrowia lipolytica 50.25 0.00e+00 840.00
IUUC-Zma-135867 Zea mays 63.08 0.00e+00 1119.00
Created Date 25-Jun-2017

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