iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_U_TGACv1_643294_AA2130350	TRIAE_CS42_U_TGACv1_643294_AA2130350.1	TRIAE_CS42_U_TGACv1_643294_AA2130350.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.60e-54	185.8	310	792
UBD/Alpha-Helix/UBA	1.00e-11	47.2	669	708

Active Site

Position(s)	Description	Evidence
319	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
755	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw........k 62
           tGl NlgN+CYm Sv+Q++++++++ + ++e +  ++  + ++ +p+ +l ++++kl + ++        +
   Q: 310  TGLVNLGNSCYMASVMQVMFSTHPFISRYFEkQSLKAAFAISQADPTLDLNMQMTKLAHGMLsgkysapsQ 380
           7************************99988832233333445689999*************7666666667 PP
   S: 63   skkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeek 133
           + ++ + pr++++++++ ++efs+++qqDa +f+ +l+d+++++                           
   Q: 381  EGQEGIRPRMFKSVIAASHPEFSSMRQQDALDFFLHLVDKVDQAN-------------------------- 425
           7788*************************************9988.......................... PP
   S: 134  kkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkke.................. 185
            + +++    + F++ ++++++c++ + ++ +r ++fl+ls+p+++ ++++++                  
   Q: 426  -PGSHELNPFTGFKFIIEERVQCPSGKVSYnKRCDNFLSLSIPLHEATNKEQLevfhekkaamdldgkevs 495
           .34445555678************9999888999***********999776669***************** PP
   S: 186  .........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
                     l+ cL+sf+  ee+ +   +y++  ++k++a k+ ++k++P++L+l++ +f + e++++++
   Q: 496  neeivrprvPLEACLASFSGGEEVPD---FYSTALNSKTTAIKTAGFKTFPDYLVLQMRKF-VMEAGWVPK 562
           ************************97...********************************.77889**** PP
   S: 248  kinkkvefpleLdlspfcts................................................... 267
           k++ ++++p+ +d+s++ ++                                                   
   Q: 563  KLDVYIDVPDIIDISHMRSNgvqpgeellpegascgnkaeparpvanedivsqlanmgfnyfacqraaint 633
           ***************99988888888888888888888888888887777777777777777777777777 PP
   S: 268  ......................................................peekqke.......... 274
                                                                 +                
   Q: 634  snagleeamnwllshmedpdinepisqdampaedtideasvqtlvsfgfpedvsR-----Mavkasggnie 699
           7777777777777777666666666666666666665555555555555555550.....05555555555 PP
   S: 275  ...................................kkkYeLiavvvHsG.slssGHYvayvknekgkWllf 309
                                              + +Y+Lia v+H+G s+++GHYva++ + +g+W  f
   Q: 700  ratewvlthpeasssvsadssasnvkddeshipdgSGRYKLIAFVSHMGtSTHCGHYVAHILK-DGRWTIF 769
           55555566666666666777777778888889999****************************.9****** PP
   S: 310  dDskVtevkeeevleetgstaYvlfYkr 337
           +D+kV ++   +  +   + +Y++f++r
   Q: 770  NDNKVAAS--VDLPK---DMGYLYFFQR 792
           *****999..68888...999*999997 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLldg 41
           +de  ++ lv+ GF+++  + a  a+++n+e+A+e++l++
   Q: 669  IDEASVQTLVSFGFPEDVSRMAVKASGGNIERATEWVLTH 708
           58899*********************************97 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MDLLRANLHK VRIPEPTNRI HKDECCVSFD TPRSEGGLYV DMNSFLGFGR EHVAWNFEKS 60
ENPVYLHIVQ RRKPEPDEAD RPLKKPTLLA IGVEGGFSEQ EPEYDVTYEI VILPEFVSLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACACCGCCGA TATCACCTGT GAGGGTGAAC AGAAGTGGCT TGGCACTTTT GAGACCCCCG 60
AACTTGCCCA CCGCGTGCGT GTGACATGGA GGTACGGCCG GAGCCGGGCC GAGCGCAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002580	Amborella trichopoda	72.70	3.00e-174	606.00
IUUC-Aly-005727	Arabidopsis lyrata	68.49	0.00e+00	1127.00
IUUC-Ath-006974	Arabidopsis thaliana	69.61	0.00e+00	1138.00
IUUC-Ago-007890	Ashbya gossypii	27.76	9.00e-71	262.00
IUUC-Acl-008057	Aspergillus clavatus	34.64	2.00e-115	410.00
IUUC-Afl-008547	Aspergillus flavus	35.61	8.00e-108	385.00
IUUC-Afu-008805	Aspergillus fumigatus	37.18	6.00e-100	358.00
IUUC-Ani-009441	Aspergillus nidulans	37.06	9.00e-92	332.00
IUUC-Ang-009720	Aspergillus niger	34.53	2.00e-108	387.00
IUUC-Aor-010111	Aspergillus oryzae	33.90	2.00e-117	417.00
IUUC-Ate-010531	Aspergillus terreus	32.64	1.00e-95	344.00
IUUC-Bgr-012183	Blumeria graminis	32.03	4.00e-104	373.00
IUUC-Bci-013858	Botrytis cinerea	32.40	2.00e-108	387.00
IUUC-Bdi-014904	Brachypodium distachyon	91.82	0.00e+00	1474.00
IUUC-Bol-015536	Brassica oleracea	69.15	0.00e+00	1122.00
IUUC-Bra-017939	Brassica rapa	68.70	0.00e+00	1120.00
IUUC-Cel-018625	Caenorhabditis elegans	33.87	1.00e-115	410.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	42.38	3.00e-120	426.00
IUUC-Cne-026831	Cryptococcus neoformans	35.16	7.00e-115	408.00
IUUC-Cme-027335	Cyanidioschyzon merolae	30.34	8.00e-38	153.00
IUUC-Dor-030130	Dipodomys ordii	42.16	4.00e-96	346.00
IUUC-Dse-031467	Dothistroma septosporum	34.66	1.00e-113	405.00
IUUC-Dme-032075	Drosophila melanogaster	44.67	0.00e+00	655.00
IUUC-Fal-037271	Ficedula albicollis	47.80	0.00e+00	703.00
IUUC-Fox-037745	Fusarium oxysporum	34.83	3.00e-114	406.00
IUUC-Fso-038158	Fusarium solani	34.12	6.00e-109	389.00
IUUC-Ggr-040098	Gaeumannomyces graminis	33.05	1.00e-106	381.00
IUUC-Gga-040635	Gallus gallus	47.08	0.00e+00	756.00
IUUC-Gma-043614	Glycine max	67.33	0.00e+00	1081.00
IUUC-Kpa-049156	Komagataella pastoris	31.84	8.00e-106	378.00
IUUC-Lpe-051523	Leersia perrieri	84.00	0.00e+00	1373.00
IUUC-Lma-053216	Leptosphaeria maculans	34.36	8.00e-106	380.00
IUUC-Mcc-055443	Macaca mulatta	47.19	0.00e+00	739.00
IUUC-Meu-056298	Macropus eugenii	50.00	5.00e-153	535.00
IUUC-Mpo-057589	Magnaporthe poae	33.09	5.00e-107	382.00
IUUC-Mtr-058680	Medicago truncatula	66.34	0.00e+00	1104.00
IUUC-Mla-058903	Melampsora laricipopulina	33.01	1.00e-104	374.00
IUUC-Mga-059669	Meleagris gallopavo	46.87	0.00e+00	707.00
IUUC-Mmr-060575	Microcebus murinus	46.96	0.00e+00	739.00
IUUC-Nfi-068558	Neosartorya fischeri	34.71	6.00e-112	399.00
IUUC-Oan-072959	Ornithorhynchus anatinus	52.28	3.00e-68	251.00
IUUC-Oba-075109	Oryza barthii	85.77	0.00e+00	1390.00
IUUC-Obr-076292	Oryza brachyantha	87.17	0.00e+00	1374.00
IUUC-Ogl-077065	Oryza glaberrima	88.29	0.00e+00	1445.00
IUUC-Ogu-078776	Oryza glumaepatula	85.77	0.00e+00	1409.00
IUUC-Oin-080048	Oryza indica	87.91	0.00e+00	1436.00
IUUC-Olo-080711	Oryza longistaminata	83.90	0.00e+00	1297.00
IUUC-Ome-081506	Oryza meridionalis	85.79	0.00e+00	1311.00
IUUC-Oni-082320	Oryza nivara	83.48	0.00e+00	1382.00
IUUC-Opu-083801	Oryza punctata	86.15	0.00e+00	1365.00
IUUC-Oru-085139	Oryza rufipogon	83.35	0.00e+00	1377.00
IUUC-Osa-085713	Oryza sativa	88.29	0.00e+00	1447.00
IUUC-Oar-089995	Ovis aries	46.32	0.00e+00	732.00
IUUC-Ptr-090640	Pan troglodytes	46.25	0.00e+00	739.00
IUUC-Pan-091974	Papio anubis	46.50	0.00e+00	733.00
IUUC-Pno-094835	Phaeosphaeria nodorum	34.41	5.00e-98	352.00
IUUC-Ppa-095901	Physcomitrella patens	60.83	0.00e+00	1014.00
IUUC-Pfo-097148	Poecilia formosa	43.62	0.00e+00	655.00
IUUC-Pop-098943	Populus trichocarpa	69.94	0.00e+00	1118.00
IUUC-Ppe-101315	Prunus persica	67.94	0.00e+00	1112.00
IUUC-Pgr-103343	Puccinia graminis	33.09	8.00e-97	348.00
IUUC-Ptt-103928	Puccinia triticina	28.72	9.00e-85	308.00
IUUC-Pte-104306	Pyrenophora teres	33.25	2.00e-93	337.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	33.37	1.00e-96	348.00
IUUC-Sce-106304	Saccharomyces cerevisiae	31.60	1.00e-71	265.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	32.27	3.00e-97	350.00
IUUC-Spo-108144	Schizosaccharomyces pombe	33.46	3.00e-106	380.00
IUUC-Smo-108848	Selaginella moellendorffii	58.30	0.00e+00	916.00
IUUC-Sit-110728	Setaria italica	86.42	0.00e+00	1431.00
IUUC-Sly-111523	Solanum lycopersicum	66.63	0.00e+00	1129.00
IUUC-Sar-113733	Sorex araneus	46.45	3.00e-93	337.00
IUUC-Sbi-114419	Sorghum bicolor	86.29	0.00e+00	1415.00
IUUC-Sre-115225	Sporisorium reilianum	33.26	1.00e-104	374.00
IUUC-Tgu-117346	Taeniopygia guttata	46.79	0.00e+00	736.00
IUUC-Tru-118350	Takifugu rubripes	41.90	0.00e+00	637.00
IUUC-Tsy-119278	Tarsius syrichta	39.20	4.00e-161	562.00
IUUC-Tni-120658	Tetraodon nigroviridis	42.46	0.00e+00	634.00
IUUC-Tca-121585	Theobroma cacao	68.89	0.00e+00	1112.00
IUUC-Tvi-122303	Trichoderma virens	33.58	1.00e-105	377.00
IUUC-Tme-126909	Tuber melanosporum	33.13	3.00e-100	360.00
IUUC-Uma-129599	Ustilago maydis	34.25	6.00e-114	405.00
IUUC-Vvi-131116	Vitis vinifera	71.15	0.00e+00	1124.00
IUUC-Xtr-131953	Xenopus tropicalis	45.10	0.00e+00	698.00
IUUC-Yli-134510	Yarrowia lipolytica	33.54	2.00e-107	384.00
IUUC-Zma-135786	Zea mays	84.53	0.00e+00	1359.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence