iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036250

Ensembl Protein ID

ENSFCAP00000011298.3

UniProt Accession

M3WGG8; M3WGG8_FELCA

Genbank Protein ID

ENSFCAP00000011298

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02069159

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000012177.3	ENSFCAT00000012180.3	ENSFCAP00000011298.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.80e-15	54.4	22	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFve 60
            + +dyea+ d+eLtl++Gd v+v++++   + degW+ g+   +g+ G+fP+n+v+
   Q: 22   TAVFDYEAAGDEELTLRRGDRVQVLSQDcavSGDEGWWTGQ-LPSGRVGVFPSNYVA 77
           589**********************77622257*******7.99***********96 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MEEEEGGTAK EWGTTPTGPV WTAVFDYEAA GDEELTLRRG DRVQVLSQDC AVSGDEGWWT 60
GQLPSGRVGV FPSNYVAPGA PAAPAGLQLP QEIPFHELQL EEIIGVGGFG KVYRALWRGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAGCCGGG GGCCGCCGGT GGAGCTGCGC GGGGTGAGAG GCGTGGGGAA GGGGGCTGCC 60
TGCTTCCCTC ACCCTCGTCC CCCACCGGCG GGCCCCGGCA GGAATTGGGG AGCCGCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0007257--P:activation of JUN kinase activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	97.27	0.00e+00	990.00
IUUC-Atr-002478	Amborella trichopoda	33.33	2.00e-24	107.00
IUUC-Aca-004768	Anolis carolinensis	76.89	0.00e+00	796.00
IUUC-Aly-006459	Arabidopsis lyrata	32.74	9.00e-29	122.00
IUUC-Ath-006581	Arabidopsis thaliana	32.38	4.00e-28	120.00
IUUC-Ame-011769	Astyanax mexicanus	64.25	0.00e+00	682.00
IUUC-Bta-013545	Bos taurus	98.93	0.00e+00	834.00
IUUC-Bdi-014449	Brachypodium distachyon	32.36	2.00e-25	110.00
IUUC-Bol-016287	Brassica oleracea	31.90	1.00e-27	118.00
IUUC-Bra-017021	Brassica rapa	32.63	4.00e-28	120.00
IUUC-Cja-019696	Callithrix jacchus	96.25	0.00e+00	968.00
IUUC-Cfa-020962	Canis familiaris	60.84	5.00e-162	565.00
IUUC-Cpo-021993	Cavia porcellus	91.26	0.00e+00	960.00
IUUC-Cre-022669	Chlamydomonas reinhardtii	33.64	5.00e-20	91.70
IUUC-Csa-024243	Chlorocebus sabaeus	96.90	0.00e+00	964.00
IUUC-Cho-024961	Choloepus hoffmanni	94.29	1.00e-108	386.00
IUUC-Dre-028573	Danio rerio	72.09	0.00e+00	761.00
IUUC-Dno-029095	Dasypus novemcinctus	93.32	0.00e+00	933.00
IUUC-Dme-032210	Drosophila melanogaster	49.67	9.00e-140	491.00
IUUC-Fal-036753	Ficedula albicollis	67.48	0.00e+00	730.00
IUUC-Gmo-038497	Gadus morhua	71.38	0.00e+00	762.00
IUUC-Gga-040283	Gallus gallus	66.23	0.00e+00	716.00
IUUC-Gac-042509	Gasterosteus aculeatus	71.24	0.00e+00	747.00
IUUC-Gma-043336	Glycine max	30.03	3.00e-26	114.00
IUUC-Ggo-045471	Gorilla gorilla	92.21	0.00e+00	906.00
IUUC-Hsa-046936	Homo sapiens	97.23	0.00e+00	954.00
IUUC-Hvu-047798	Hordeum vulgare	32.27	3.00e-24	107.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	95.84	0.00e+00	978.00
IUUC-Lch-049935	Latimeria chalumnae	73.71	0.00e+00	784.00
IUUC-Loc-052286	Lepisosteus oculatus	68.24	0.00e+00	754.00
IUUC-Laf-053926	Loxodonta africana	65.46	0.00e+00	744.00
IUUC-Mcc-055733	Macaca mulatta	94.03	0.00e+00	957.00
IUUC-Mtr-058733	Medicago truncatula	32.84	1.00e-26	115.00
IUUC-Mmr-061210	Microcebus murinus	63.19	0.00e+00	734.00
IUUC-Mdo-062516	Monodelphis domestica	81.59	0.00e+00	884.00
IUUC-Mmu-064082	Mus musculus	95.49	0.00e+00	972.00
IUUC-Mac-065156	Musa acuminata	31.93	3.00e-28	120.00
IUUC-Mpu-065934	Mustela putorius furo	98.39	0.00e+00	1009.00
IUUC-Mlu-068137	Myotis lucifugus	83.13	0.00e+00	914.00
IUUC-Nle-068969	Nomascus leucogenys	64.34	0.00e+00	724.00
IUUC-Opr-070869	Ochotona princeps	76.46	0.00e+00	768.00
IUUC-Ont-072492	Oreochromis niloticus	71.52	0.00e+00	778.00
IUUC-Ocu-074350	Oryctolagus cuniculus	90.74	0.00e+00	939.00
IUUC-Oba-075616	Oryza barthii	34.11	4.00e-25	109.00
IUUC-Obr-076215	Oryza brachyantha	34.10	3.00e-26	114.00
IUUC-Ogl-077159	Oryza glaberrima	34.11	4.00e-25	110.00
IUUC-Ogu-078228	Oryza glumaepatula	34.58	1.00e-25	111.00
IUUC-Oin-079079	Oryza indica	34.21	1.00e-25	112.00
IUUC-Olo-080309	Oryza longistaminata	34.29	1.00e-24	108.00
IUUC-Oni-082428	Oryza nivara	34.11	4.00e-25	110.00
IUUC-Opu-083527	Oryza punctata	34.58	3.00e-25	110.00
IUUC-Oru-084678	Oryza rufipogon	34.21	1.00e-25	112.00
IUUC-Osa-086117	Oryza sativa	34.21	1.00e-25	112.00
IUUC-Ola-087224	Oryzias latipes	71.15	0.00e+00	774.00
IUUC-Oga-088351	Otolemur garnettii	95.09	0.00e+00	1002.00
IUUC-Ptr-091607	Pan troglodytes	97.23	0.00e+00	954.00
IUUC-Pan-092403	Papio anubis	96.74	0.00e+00	948.00
IUUC-Pma-094398	Petromyzon marinus	65.83	8.00e-175	607.00
IUUC-Pfo-096104	Poecilia formosa	69.08	0.00e+00	743.00
IUUC-Pab-098396	Pongo abelii	97.23	0.00e+00	956.00
IUUC-Pop-099554	Populus trichocarpa	29.59	2.00e-24	108.00
IUUC-Pca-100945	Procavia capensis	57.28	5.00e-176	612.00
IUUC-Ppe-101208	Prunus persica	34.55	1.00e-26	114.00
IUUC-Pva-102748	Pteropus vampyrus	66.96	0.00e+00	692.00
IUUC-Rno-105688	Rattus norvegicus	95.49	0.00e+00	975.00
IUUC-Smo-109113	Selaginella moellendorffii	32.72	9.00e-26	110.00
IUUC-Sit-110427	Setaria italica	34.58	2.00e-25	110.00
IUUC-Sly-111849	Solanum lycopersicum	35.09	1.00e-25	112.00
IUUC-Stu-112224	Solanum tuberosum	35.09	2.00e-25	111.00
IUUC-Sbi-113963	Sorghum bicolor	35.05	5.00e-26	112.00
IUUC-Ssc-115332	Sus scrofa	97.01	0.00e+00	988.00
IUUC-Tru-117692	Takifugu rubripes	69.51	0.00e+00	769.00
IUUC-Tsy-119412	Tarsius syrichta	94.12	3.00e-65	242.00
IUUC-Tni-120689	Tetraodon nigroviridis	68.53	0.00e+00	753.00
IUUC-Tca-121565	Theobroma cacao	35.38	2.00e-26	114.00
IUUC-Tae-125555	Triticum aestivum	32.73	1.00e-24	108.00
IUUC-Tur-126322	Triticum urartu	32.26	4.00e-25	109.00
IUUC-Tbe-127643	Tupaia belangeri	98.31	0.00e+00	671.00
IUUC-Ttr-128550	Tursiops truncatus	94.38	0.00e+00	1016.00
IUUC-Vvi-131372	Vitis vinifera	32.26	2.00e-23	104.00
IUUC-Xtr-132108	Xenopus tropicalis	73.37	0.00e+00	800.00
IUUC-Xma-134254	Xiphophorus maculatus	69.36	0.00e+00	759.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence