iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042140

UUCD1 version

UUC-GaA-00698

Ensembl Protein ID

ENSGACP00000018050.1

UniProt Accession

G3PKC0; G3PKC0_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000013651.1	ENSGACT00000018085.1	ENSGACP00000018050.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-30	104.2	174	208
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	8.90e-13	48.3	381	425
UBD/Beta-Prp	1.00e-45	156.6	139	385

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Htd v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 174  HTDIVRDLTFaPDgsLMLVSASRDKTLRVWDLKDD 208
           ***********7767889*************9887 PP

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
            +w++++++ SLqh+CR++ rr +++q++   ++L +P  L+d+L y+
   Q: 381  HFWECPRSVASLQHICRMSLRRVMTTQQV---ETLAIPMPLRDFLTYK 425
           69************************999...**************98 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +d+ llatg  +g+ik+wdv tgkll  l +h++ v++++f pdg+ +lv++s+D+t++vwdl+ +g +v +l+gh++ v++ +f
   Q: 139  FKFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLMDHTDIVRDLTFAPDGSlMLVSASRDKTLRVWDLKdDGNMVKVLRGHQNWVYCSAF 227
           67899999*****************************************999***************9899****************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +w++++ + ++  l+gh+  v + +++pdg ll+++s+D+ v +Wd   +++l +l             g++
   Q: 228  SPDSSILCSVGAGKAVFLWNMDKLTLMR-KLEGHHNDVVSCEFSPDGALLATASYDTRVIVWDPHKATVLLELghlfpppspifaGGAN 315
           ***************************9.999999999999*******************************************98889 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           ++ v+s+sf+++g++++s+ +d+ v++w++++     +  g     ++ +fs ++  l+ g+  gs+ +W +
   Q: 316  DRWVRSVSFSPDGRHIASITDDRLVRFWSIEER--APQAVGSLPSGLCCAFSADGSVLAAGTRGGSVHFWEC 385
           9*****************************877..689999999999***********************77 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MASFPDSVNE NDIGQAKFIG ELLVPVAPFD QKSGREAWTV AFAPNGSYFA WSQGHRIVRL 60
IPWAKCLKNF SIGHDGEATN ALSPRRLSRQ NSGEGQLIPE ADEPREHTID CGDVVWGLAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGACGACTA TATTCTCCAC CCGGGTCGCT ACACTTGGCG GAGGGATACT ACAGACGTTA 60
GCAGACATCG GGCGGACAAG CCGCGCGTAG TCGCCGAGTT CCTCTTGAAA CCTTCATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR023294--Tachylectin2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	72.77	0.00e+00	647.00
IUUC-Apl-003903	Anas platyrhynchos	73.61	0.00e+00	645.00
IUUC-Aca-005214	Anolis carolinensis	63.81	3.00e-165	574.00
IUUC-Ame-011740	Astyanax mexicanus	83.84	0.00e+00	750.00
IUUC-Bta-013475	Bos taurus	73.24	0.00e+00	653.00
IUUC-Cja-019053	Callithrix jacchus	74.53	0.00e+00	664.00
IUUC-Cfa-020103	Canis familiaris	73.24	0.00e+00	652.00
IUUC-Cpo-022438	Cavia porcellus	73.24	0.00e+00	657.00
IUUC-Csa-024062	Chlorocebus sabaeus	74.18	0.00e+00	668.00
IUUC-Cho-024334	Choloepus hoffmanni	65.96	1.00e-164	572.00
IUUC-Cin-025590	Ciona intestinalis	40.79	1.00e-76	280.00
IUUC-Csv-026023	Ciona savignyi	40.33	6.00e-76	277.00
IUUC-Dre-028089	Danio rerio	84.31	0.00e+00	750.00
IUUC-Dno-029436	Dasypus novemcinctus	76.76	1.00e-157	549.00
IUUC-Dor-031107	Dipodomys ordii	68.31	3.00e-170	591.00
IUUC-Ete-032326	Echinops telfairi	72.93	0.00e+00	632.00
IUUC-Eca-033401	Equus caballus	73.24	0.00e+00	651.00
IUUC-Eeu-034520	Erinaceus europaeus	72.07	0.00e+00	649.00
IUUC-Fca-036386	Felis catus	72.30	0.00e+00	651.00
IUUC-Fal-036616	Ficedula albicollis	71.67	0.00e+00	625.00
IUUC-Gmo-039335	Gadus morhua	80.63	0.00e+00	688.00
IUUC-Gga-040856	Gallus gallus	73.71	0.00e+00	659.00
IUUC-Ggo-044619	Gorilla gorilla	74.41	0.00e+00	669.00
IUUC-Hsa-046300	Homo sapiens	74.18	0.00e+00	667.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	74.18	0.00e+00	668.00
IUUC-Lch-049550	Latimeria chalumnae	73.28	1.00e-157	548.00
IUUC-Loc-051769	Lepisosteus oculatus	80.94	0.00e+00	711.00
IUUC-Laf-054576	Loxodonta africana	73.71	0.00e+00	658.00
IUUC-Mcc-054666	Macaca mulatta	75.95	2.00e-121	428.00
IUUC-Meu-055989	Macropus eugenii	74.21	4.00e-156	543.00
IUUC-Mga-059722	Meleagris gallopavo	72.55	0.00e+00	645.00
IUUC-Mmr-060970	Microcebus murinus	73.00	0.00e+00	650.00
IUUC-Mdo-062249	Monodelphis domestica	63.38	4.00e-152	531.00
IUUC-Mmu-063742	Mus musculus	72.71	0.00e+00	650.00
IUUC-Mpu-066518	Mustela putorius furo	74.18	0.00e+00	667.00
IUUC-Mlu-068063	Myotis lucifugus	71.60	0.00e+00	639.00
IUUC-Nle-069561	Nomascus leucogenys	74.65	0.00e+00	671.00
IUUC-Opr-071158	Ochotona princeps	71.29	0.00e+00	635.00
IUUC-Ont-072542	Oreochromis niloticus	88.76	0.00e+00	791.00
IUUC-Oan-073217	Ornithorhynchus anatinus	74.65	0.00e+00	671.00
IUUC-Ocu-074251	Oryctolagus cuniculus	73.54	0.00e+00	635.00
IUUC-Ola-086549	Oryzias latipes	85.01	0.00e+00	774.00
IUUC-Oga-088382	Otolemur garnettii	73.00	0.00e+00	652.00
IUUC-Oar-090263	Ovis aries	73.24	0.00e+00	652.00
IUUC-Ptr-090922	Pan troglodytes	74.41	0.00e+00	669.00
IUUC-Pan-092518	Papio anubis	74.18	0.00e+00	668.00
IUUC-Psi-093512	Pelodiscus sinensis	74.18	0.00e+00	664.00
IUUC-Pma-094324	Petromyzon marinus	57.87	2.00e-137	481.00
IUUC-Pfo-096264	Poecilia formosa	87.59	0.00e+00	787.00
IUUC-Pab-098018	Pongo abelii	73.00	0.00e+00	656.00
IUUC-Pca-101034	Procavia capensis	71.84	7.00e-177	612.00
IUUC-Pva-102862	Pteropus vampyrus	69.72	2.00e-172	598.00
IUUC-Rno-106116	Rattus norvegicus	73.24	0.00e+00	659.00
IUUC-Sha-106952	Sarcophilus harrisii	71.84	0.00e+00	626.00
IUUC-Sar-113211	Sorex araneus	65.63	4.00e-121	427.00
IUUC-Ssc-116440	Sus scrofa	73.00	0.00e+00	650.00
IUUC-Tgu-116675	Taeniopygia guttata	72.15	4.00e-180	624.00
IUUC-Tru-118295	Takifugu rubripes	84.07	0.00e+00	750.00
IUUC-Tsy-118916	Tarsius syrichta	61.27	2.00e-153	535.00
IUUC-Tni-120302	Tetraodon nigroviridis	84.78	0.00e+00	749.00
IUUC-Tbe-127416	Tupaia belangeri	63.83	3.00e-150	524.00
IUUC-Ttr-128185	Tursiops truncatus	73.47	0.00e+00	652.00
IUUC-Xtr-132465	Xenopus tropicalis	73.54	0.00e+00	669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence