iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120302

UUCD1 version

UUC-TeN-01033

Ensembl Protein ID

ENSTNIP00000007650.1

UniProt Accession

H3CHC2; H3CHC2_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000004985.1	ENSTNIT00000007811.1	ENSTNIP00000007650.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-28	96.6	173	207
UBD/Beta-Prp	6.60e-47	160.3	138	384

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Htd v++l f +d   +lvs+s D+t++vWDl+++
   Q: 173  HTDIVRDLTFaPDgsLMLVSASTDKTLRVWDLKDD 207
           ***********7767889*************9887 PP

UBD/Beta-Prp

   S: 17   kf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
           +f  +d+ llatg  +g+ik+wdv tg+ll  l +h++ v++++f pdg+ +lv++s+D+t++vwdl+ +g +v +l+gh+++v+s +f
   Q: 138  HFrFQDQLLLATGLSNGRIKIWDVYTGTLLLNLMDHTDIVRDLTFAPDGSlMLVSASTDKTLRVWDLKdDGNMVKVLRGHQNRVYSSAF 226
           555589999*****************************************99***************989******************* PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +w+++ ++ ++  l+gh+  v + +++pdg ll+++s+D+ v +Wd + g++l +l             g++
   Q: 227  SPDSSILCSVGAGKAVLLWNMDRYTLIR-RLEGHHNDVVSCEFSPDGALLATASYDTRVIVWDHQKGSVLLELghlfpppspifaGGAN 314
           ***************************9.9999999999*********************************************98889 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           ++ v+s+sf  +g++++s+++d+ v++w++++     +  +   n ++ +fs  +  l+ g++Dgs+ +W +
   Q: 315  DRWVRSVSFCADGRHIASVADDRLVRFWSMEER--APQAVASLPNGLCCAFSTTGSVLAAGTCDGSVHFWEC 384
           ******************************877..68889999999999*********************76 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MASFPDSVNE NDIEKAKFIG ELLVPTAPFD QKSGCETWTV AFAPDGSYFA WSQGHRVVSL 60
IPWTKCLKSF SVGHGGEITN PTSPRHFSRH SSKGGSVIPV AGEPPEHTID CGDIVWGLAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAAGCT TCCCAGACTC TGTAAACGAA AATGATATAG GTGAGTTTGT TTTCAAGGTC 60
GCATCTTCTC ACCCTTAAAA ATATTTTTTT GTGGGCAGGT CTCCAGCGTG CTCGTTTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR023294--Tachylectin2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	71.13	3.00e-179	620.00
IUUC-Apl-003903	Anas platyrhynchos	70.87	7.00e-176	609.00
IUUC-Aca-005214	Anolis carolinensis	62.65	5.00e-157	546.00
IUUC-Ame-011740	Astyanax mexicanus	80.33	0.00e+00	706.00
IUUC-Bta-013475	Bos taurus	71.60	0.00e+00	626.00
IUUC-Cja-019053	Callithrix jacchus	71.70	0.00e+00	630.00
IUUC-Cfa-020103	Canis familiaris	71.60	1.00e-180	625.00
IUUC-Cpo-022438	Cavia porcellus	71.13	0.00e+00	630.00
IUUC-Csa-024062	Chlorocebus sabaeus	71.60	0.00e+00	635.00
IUUC-Cho-024334	Choloepus hoffmanni	63.62	4.00e-154	537.00
IUUC-Cin-025590	Ciona intestinalis	41.00	6.00e-75	274.00
IUUC-Csv-026023	Ciona savignyi	40.76	6.00e-74	271.00
IUUC-Dre-028089	Danio rerio	79.39	0.00e+00	694.00
IUUC-Dno-029436	Dasypus novemcinctus	74.38	8.00e-148	516.00
IUUC-Dor-031107	Dipodomys ordii	67.14	4.00e-163	567.00
IUUC-Ete-032326	Echinops telfairi	71.46	7.00e-174	602.00
IUUC-Eca-033401	Equus caballus	71.36	5.00e-180	623.00
IUUC-Eeu-034520	Erinaceus europaeus	71.13	0.00e+00	627.00
IUUC-Fca-036386	Felis catus	70.89	1.00e-179	622.00
IUUC-Fal-036616	Ficedula albicollis	69.40	4.00e-172	597.00
IUUC-Gmo-039335	Gadus morhua	77.97	0.00e+00	647.00
IUUC-Gga-040856	Gallus gallus	71.13	0.00e+00	626.00
IUUC-Gac-042140	Gasterosteus aculeatus	84.78	0.00e+00	749.00
IUUC-Ggo-044619	Gorilla gorilla	71.83	0.00e+00	637.00
IUUC-Hsa-046300	Homo sapiens	71.60	0.00e+00	635.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	71.13	0.00e+00	634.00
IUUC-Lch-049550	Latimeria chalumnae	72.41	8.00e-149	519.00
IUUC-Loc-051769	Lepisosteus oculatus	78.59	0.00e+00	677.00
IUUC-Laf-054576	Loxodonta africana	71.83	0.00e+00	628.00
IUUC-Mcc-054666	Macaca mulatta	74.81	7.00e-118	416.00
IUUC-Meu-055989	Macropus eugenii	72.78	3.00e-149	521.00
IUUC-Mga-059722	Meleagris gallopavo	69.93	5.00e-177	613.00
IUUC-Mmr-060970	Microcebus murinus	71.60	1.00e-180	625.00
IUUC-Mdo-062249	Monodelphis domestica	62.91	5.00e-146	510.00
IUUC-Mmu-063742	Mus musculus	70.12	2.00e-180	624.00
IUUC-Mpu-066518	Mustela putorius furo	71.60	0.00e+00	634.00
IUUC-Mlu-068063	Myotis lucifugus	70.42	3.00e-176	610.00
IUUC-Nle-069561	Nomascus leucogenys	72.07	0.00e+00	638.00
IUUC-Opr-071158	Ochotona princeps	69.88	4.00e-178	617.00
IUUC-Ont-072542	Oreochromis niloticus	85.25	0.00e+00	753.00
IUUC-Oan-073217	Ornithorhynchus anatinus	72.71	0.00e+00	641.00
IUUC-Ocu-074251	Oryctolagus cuniculus	71.84	4.00e-176	610.00
IUUC-Ola-086549	Oryzias latipes	80.56	0.00e+00	727.00
IUUC-Oga-088382	Otolemur garnettii	71.13	1.00e-180	625.00
IUUC-Oar-090263	Ovis aries	70.66	5.00e-179	620.00
IUUC-Ptr-090922	Pan troglodytes	71.83	0.00e+00	636.00
IUUC-Pan-092518	Papio anubis	71.60	0.00e+00	635.00
IUUC-Psi-093512	Pelodiscus sinensis	71.60	0.00e+00	629.00
IUUC-Pma-094324	Petromyzon marinus	58.33	3.00e-136	478.00
IUUC-Pfo-096264	Poecilia formosa	84.07	0.00e+00	754.00
IUUC-Pab-098018	Pongo abelii	70.19	2.00e-179	621.00
IUUC-Pca-101034	Procavia capensis	71.12	2.00e-168	584.00
IUUC-Pva-102862	Pteropus vampyrus	68.08	1.00e-162	565.00
IUUC-Rno-106116	Rattus norvegicus	71.13	0.00e+00	630.00
IUUC-Sha-106952	Sarcophilus harrisii	71.36	4.00e-173	600.00
IUUC-Sar-113211	Sorex araneus	64.71	4.00e-116	410.00
IUUC-Ssc-116440	Sus scrofa	71.36	5.00e-180	623.00
IUUC-Tgu-116675	Taeniopygia guttata	69.17	1.00e-170	592.00
IUUC-Tru-118295	Takifugu rubripes	91.10	0.00e+00	811.00
IUUC-Tsy-118916	Tarsius syrichta	61.27	1.00e-148	518.00
IUUC-Tbe-127416	Tupaia belangeri	61.17	4.00e-142	497.00
IUUC-Ttr-128185	Tursiops truncatus	71.83	0.00e+00	625.00
IUUC-Xtr-132465	Xenopus tropicalis	70.96	0.00e+00	630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence