iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120716

Ensembl Protein ID

ENSTNIP00000012568.1

UniProt Accession

H3CWD4; H3CWD4_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000009688.1	ENSTNIT00000012759.1	ENSTNIP00000012568.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-32	110.8	181	218
UBD/Beta-Prp	7.00e-65	219.3	182	395

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 181  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWGTDDGRLL 218
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h s ++cv+f + ++ ++tgs+d  +k+w +++g ll++l gh ae++++  s +  +++ gs D+ti+vw l+t+ ++ +l+gh +s+
   Q: 182  HLSSVYCVTFDRTGRRIFTGSDDCLVKIWGTDDGRLLATLRGHAAEISDMAVSYENTMIAAGSCDKTIRVWCLQTCAPLAVLEGHAASI 270
           5567889*************************************************9******************************** PP
   S: 98   lslsfsp....sgdklvsGshdrtirvwdletgqclee......tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkl..lr 173
           +sl+fsp    s+ +l s+++d ti  w++++++          t++ + gv ++ ++ + g   l++Gs+D ++r++   +g+   + 
   Q: 271  TSLQFSPlcsgSKRYLSSTGADGTICFWQWDSRTLKFGqrpskfTERSRPGVQMICSSFSAGgMFLATGSTDHIIRVYYFGSGQPekIS 359
           *********877799************88888876655679999999999999988777777799*************99666651166 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlq 210
           +l++ htd+v s++f++ + ++vsgs+dgt ++w+lq
   Q: 360  ELES-HTDKVDSIQFSHCSDRFVSGSRDGTARIWQLQ 395
           7788.******************************99 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MASDSTHIAQ LTSELYFLIA RFLEAGPCQK AAETLIREVE EKELLPKRLD WTGQEHPGTY 60
ENLVKLYRHV SADHLLQVCS KVCPLLEREV PASVPGLTSL LGAGRQNLLR TSKSCKHVVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG ACAGTACACA CATCGCGCAG TTGACTTCTG GTGAGTAAAG GAGATTGTAA 60
CATGTGTCAC GGTCGTTTTA ATAGCCCCAC AATTTCCTCG GTGCCCTGTT CTAACGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0008286--P:insulin receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	31.70	6.00e-63	236.00
IUUC-Atr-002600	Amborella trichopoda	31.56	3.00e-70	261.00
IUUC-Aly-006406	Arabidopsis lyrata	33.08	8.00e-71	263.00
IUUC-Ath-006801	Arabidopsis thaliana	32.04	3.00e-70	261.00
IUUC-Bdi-014797	Brachypodium distachyon	30.88	6.00e-58	220.00
IUUC-Bol-015737	Brassica oleracea	31.79	7.00e-74	273.00
IUUC-Bra-017961	Brassica rapa	31.75	2.00e-73	271.00
IUUC-Cpo-022077	Cavia porcellus	60.13	0.00e+00	1993.00
IUUC-Cho-024794	Choloepus hoffmanni	75.27	0.00e+00	709.00
IUUC-Csv-025813	Ciona savignyi	44.16	0.00e+00	642.00
IUUC-Dre-028029	Danio rerio	81.52	0.00e+00	1426.00
IUUC-Dno-030048	Dasypus novemcinctus	73.96	0.00e+00	1281.00
IUUC-Dor-030195	Dipodomys ordii	70.91	0.00e+00	1122.00
IUUC-Dme-031752	Drosophila melanogaster	52.33	0.00e+00	672.00
IUUC-Eeu-034688	Erinaceus europaeus	79.55	0.00e+00	1102.00
IUUC-Fal-037307	Ficedula albicollis	66.62	0.00e+00	1061.00
IUUC-Gmo-039451	Gadus morhua	77.06	0.00e+00	777.00
IUUC-Gma-043340	Glycine max	31.69	3.00e-70	261.00
IUUC-Ggo-045500	Gorilla gorilla	58.23	0.00e+00	1639.00
IUUC-Hvu-047706	Hordeum vulgare	31.46	3.00e-38	152.00
IUUC-Loc-052672	Lepisosteus oculatus	78.45	0.00e+00	2240.00
IUUC-Meu-056321	Macropus eugenii	55.51	0.00e+00	789.00
IUUC-Mtr-058094	Medicago truncatula	32.12	1.00e-70	261.00
IUUC-Mdo-061903	Monodelphis domestica	76.48	0.00e+00	1362.00
IUUC-Mac-065343	Musa acuminata	31.14	2.00e-73	271.00
IUUC-Opr-070971	Ochotona princeps	70.31	0.00e+00	660.00
IUUC-Ont-072221	Oreochromis niloticus	83.23	0.00e+00	2778.00
IUUC-Obr-076619	Oryza brachyantha	30.79	4.00e-68	253.00
IUUC-Ogl-077493	Oryza glaberrima	37.84	2.00e-28	121.00
IUUC-Oin-079669	Oryza indica	32.48	7.00e-53	202.00
IUUC-Olo-080755	Oryza longistaminata	32.27	3.00e-53	204.00
IUUC-Opu-083233	Oryza punctata	30.50	5.00e-63	237.00
IUUC-Ola-086648	Oryzias latipes	84.08	0.00e+00	2467.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.84	6.00e-55	209.00
IUUC-Ptr-091213	Pan troglodytes	58.14	0.00e+00	1639.00
IUUC-Pma-094427	Petromyzon marinus	62.84	7.00e-125	439.00
IUUC-Ppa-095793	Physcomitrella patens	30.05	6.00e-70	259.00
IUUC-Pfo-096191	Poecilia formosa	79.74	0.00e+00	2701.00
IUUC-Pop-099803	Populus trichocarpa	33.83	7.00e-77	282.00
IUUC-Pca-101128	Procavia capensis	81.21	0.00e+00	1211.00
IUUC-Ppe-101849	Prunus persica	31.43	6.00e-73	270.00
IUUC-Sit-110017	Setaria italica	31.81	4.00e-55	210.00
IUUC-Sly-111348	Solanum lycopersicum	31.73	1.00e-74	275.00
IUUC-Sbi-114195	Sorghum bicolor	30.37	2.00e-57	216.00
IUUC-Ssc-115461	Sus scrofa	69.27	0.00e+00	1178.00
IUUC-Tgu-116513	Taeniopygia guttata	66.14	0.00e+00	1061.00
IUUC-Tru-117625	Takifugu rubripes	91.21	0.00e+00	3033.00
IUUC-Tca-121615	Theobroma cacao	31.31	3.00e-68	254.00
IUUC-Tae-125478	Triticum aestivum	30.56	1.00e-71	265.00
IUUC-Tur-126809	Triticum urartu	30.48	2.00e-69	258.00
IUUC-Tbe-127479	Tupaia belangeri	67.02	0.00e+00	1006.00
IUUC-Vpa-130160	Vicugna pacos	76.21	0.00e+00	1244.00
IUUC-Vvi-131332	Vitis vinifera	32.52	2.00e-76	281.00
IUUC-Xma-134120	Xiphophorus maculatus	93.79	0.00e+00	1575.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence