iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044682

UUCD1 version

UUC-GoG-00280

Ensembl Protein ID

ENSGGOP00000006800.2

UniProt Accession

G3QVM3; G3QVM3_GORGO

Protein Name

Uncharacterized protein

Gene Name

PRPF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000006943.2	ENSGGOT00000006979.2	ENSGGOP00000006800.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-38	128.5	421	459
UBD/Beta-Prp	1.70e-93	313.5	246	493

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH  ++++++f ++  ++++Gs+D+t+kvWDlr+ +++ 
   Q: 421  GHLKEIYGINFsPNgYHIATGSGDNTCKVWDLRQRRCVY 459
           7999********77799*****************99985 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdlstgkcvht 89
           ++ +i+  +fsp++++lat++++g  k+w+v + +ll++l gh+  v a+ f+p++          l++++ D+ +k+w+l++ ++v  
   Q: 246  DDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTvsldpkdvNLASCAADGSVKLWSLDSDEPVAD 334
           67899999**************************************99999999988888899999*********************** PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++gh+ +v  + ++psg +l ++  dr  r+wdle ++++   ++gh+  v  +++h+dg+l  +G+lD + r+Wdl+tg+++  l+g 
   Q: 335  IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEIL-HQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG- 421
           *****************************************.********************************************99. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriW 249
           h + +y ++f++ng ++++gs d+t k+wdl++ +cv+t  +h++ v+ v+f   ++++l++g+ D++ +iW
   Q: 422  HLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEpIHGNFLLTGAYDNTAKIW 493
           *****************************************************88***************** PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

KGVFGFRWGL AAPEPSMASS RASSTATKTK APDDLVAPVV KKPHIYYGSL EEKERERLAK 60
GESGILGKDG LKAGIEAGNI NITSVGEVFE IEEHISERQA EVLAEFERRK RARQINVSTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACTTCCCC TCTGCTGGGC GCGCGGTGGA CCGTCTGAAA GGGAGTGTTC GGATTTCGCT 60
GGGGCCTCGC GGCTCCAGAG CCCAGCATGG CTTCCTCGCG AGCCTCCTCC ACGGTACAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR014906--PRP4-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08799--PRP4
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00500--SFM
SM00320--WD40

Gene Ontology

GO:0015030--C:Cajal body
GO:0016607--C:nuclear speck
GO:0071001--C:U4/U6 snRNP

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000771	Aegilops tauschii	44.63	2.00e-100	358.00
IUUC-Aml-001737	Ailuropoda melanoleuca	98.13	0.00e+00	1021.00
IUUC-Atr-002828	Amborella trichopoda	43.33	2.00e-103	369.00
IUUC-Apl-003723	Anas platyrhynchos	88.59	0.00e+00	947.00
IUUC-Aca-004972	Anolis carolinensis	90.25	0.00e+00	897.00
IUUC-Aly-006531	Arabidopsis lyrata	43.15	1.00e-94	340.00
IUUC-Ath-007367	Arabidopsis thaliana	44.03	2.00e-108	386.00
IUUC-Ago-007893	Ashbya gossypii	32.89	4.00e-55	208.00
IUUC-Acl-008236	Aspergillus clavatus	37.71	4.00e-90	325.00
IUUC-Afl-008522	Aspergillus flavus	39.37	1.00e-98	353.00
IUUC-Afu-008904	Aspergillus fumigatus	37.98	6.00e-95	341.00
IUUC-Ani-009198	Aspergillus nidulans	39.58	7.00e-98	350.00
IUUC-Ang-009662	Aspergillus niger	42.51	4.00e-99	355.00
IUUC-Aor-009881	Aspergillus oryzae	40.21	2.00e-98	353.00
IUUC-Ate-010333	Aspergillus terreus	38.02	7.00e-88	317.00
IUUC-Ame-011697	Astyanax mexicanus	80.43	0.00e+00	811.00
IUUC-Bgr-012254	Blumeria graminis	38.76	4.00e-97	348.00
IUUC-Bta-012615	Bos taurus	98.47	0.00e+00	990.00
IUUC-Bci-013720	Botrytis cinerea	38.84	4.00e-99	355.00
IUUC-Bdi-014302	Brachypodium distachyon	45.43	9.00e-109	387.00
IUUC-Bol-015594	Brassica oleracea	43.10	2.00e-98	353.00
IUUC-Bra-017465	Brassica rapa	42.89	1.00e-98	353.00
IUUC-Cel-018632	Caenorhabditis elegans	45.91	5.00e-108	384.00
IUUC-Cja-019747	Callithrix jacchus	99.24	0.00e+00	1032.00
IUUC-Cfa-020288	Canis familiaris	98.50	0.00e+00	1023.00
IUUC-Cpo-021440	Cavia porcellus	96.82	0.00e+00	1013.00
IUUC-Cre-022716	Chlamydomonas reinhardtii	48.03	4.00e-87	314.00
IUUC-Csa-023139	Chlorocebus sabaeus	99.70	0.00e+00	704.00
IUUC-Cho-024481	Choloepus hoffmanni	95.80	0.00e+00	865.00
IUUC-Cin-025106	Ciona intestinalis	59.11	3.00e-177	614.00
IUUC-Csv-026087	Ciona savignyi	57.54	5.00e-175	607.00
IUUC-Cgl-026538	Colletotrichum gloeosporioides	37.93	3.00e-93	336.00
IUUC-Cne-026793	Cryptococcus neoformans	41.29	6.00e-105	374.00
IUUC-Dre-028723	Danio rerio	79.05	0.00e+00	788.00
IUUC-Dno-029299	Dasypus novemcinctus	98.82	0.00e+00	1004.00
IUUC-Dor-030345	Dipodomys ordii	100.00	5.00e-69	254.00
IUUC-Dse-031562	Dothistroma septosporum	36.13	1.00e-89	323.00
IUUC-Dme-031783	Drosophila melanogaster	57.30	4.00e-140	491.00
IUUC-Ete-032669	Echinops telfairi	96.95	0.00e+00	1008.00
IUUC-Eca-033566	Equus caballus	99.07	0.00e+00	1011.00
IUUC-Eeu-034524	Erinaceus europaeus	98.74	1.00e-145	509.00
IUUC-Fca-036215	Felis catus	99.41	0.00e+00	1008.00
IUUC-Fal-037018	Ficedula albicollis	90.00	0.00e+00	790.00
IUUC-Fox-037936	Fusarium oxysporum	37.42	1.00e-86	313.00
IUUC-Fso-038366	Fusarium solani	38.43	4.00e-92	331.00
IUUC-Gmo-038966	Gadus morhua	66.95	3.00e-140	491.00
IUUC-Ggr-039942	Gaeumannomyces graminis	36.90	9.00e-86	310.00
IUUC-Gga-040797	Gallus gallus	91.04	0.00e+00	931.00
IUUC-Gac-042598	Gasterosteus aculeatus	69.05	0.00e+00	659.00
IUUC-Gma-044220	Glycine max	44.42	8.00e-103	367.00
IUUC-Hsa-045804	Homo sapiens	99.62	0.00e+00	1036.00
IUUC-Hvu-047567	Hordeum vulgare	44.42	1.00e-94	340.00
IUUC-Itr-047882	Ictidomys tridecemlineatus	98.85	0.00e+00	1031.00
IUUC-Kpa-049369	Komagataella pastoris	33.24	2.00e-61	229.00
IUUC-Lch-050074	Latimeria chalumnae	80.38	0.00e+00	821.00
IUUC-Lpe-051333	Leersia perrieri	44.26	3.00e-99	355.00
IUUC-Loc-052164	Lepisosteus oculatus	81.42	0.00e+00	833.00
IUUC-Lma-053088	Leptosphaeria maculans	37.10	1.00e-84	306.00
IUUC-Laf-053460	Loxodonta africana	98.47	0.00e+00	1024.00
IUUC-Mcc-055859	Macaca mulatta	99.41	0.00e+00	1008.00
IUUC-Meu-056134	Macropus eugenii	94.76	0.00e+00	986.00
IUUC-Mor-057251	Magnaporthe oryzae	37.23	1.00e-85	310.00
IUUC-Mpo-057375	Magnaporthe poae	40.40	6.00e-54	203.00
IUUC-Mtr-057656	Medicago truncatula	44.50	1.00e-92	333.00
IUUC-Mla-059145	Melampsora laricipopulina	40.44	2.00e-101	362.00
IUUC-Mga-059855	Meleagris gallopavo	87.08	0.00e+00	939.00
IUUC-Mvi-060372	Microbotryum violaceum	41.98	2.00e-93	336.00
IUUC-Mmr-060826	Microcebus murinus	97.57	0.00e+00	1024.00
IUUC-Mdo-062748	Monodelphis domestica	95.45	0.00e+00	976.00
IUUC-Mmu-063351	Mus musculus	99.01	0.00e+00	1004.00
IUUC-Mac-064846	Musa acuminata	44.70	9.00e-96	343.00
IUUC-Mpu-066006	Mustela putorius furo	99.41	0.00e+00	1008.00
IUUC-Mlu-067398	Myotis lucifugus	98.13	0.00e+00	1021.00
IUUC-Nfi-068399	Neosartorya fischeri	37.98	4.00e-100	358.00
IUUC-Ncr-068711	Neurospora crassa	37.92	2.00e-93	336.00
IUUC-Nle-069982	Nomascus leucogenys	99.24	0.00e+00	1032.00
IUUC-Opr-070596	Ochotona princeps	98.47	0.00e+00	1027.00
IUUC-Ont-072374	Oreochromis niloticus	75.14	0.00e+00	750.00
IUUC-Oan-073166	Ornithorhynchus anatinus	94.37	0.00e+00	749.00
IUUC-Ocu-074371	Oryctolagus cuniculus	99.21	0.00e+00	1007.00
IUUC-Oba-075083	Oryza barthii	43.86	2.00e-102	366.00
IUUC-Obr-076405	Oryza brachyantha	44.03	7.00e-99	353.00
IUUC-Ogl-077683	Oryza glaberrima	43.86	3.00e-102	365.00
IUUC-Ogu-078486	Oryza glumaepatula	44.09	3.00e-102	365.00
IUUC-Oin-079679	Oryza indica	44.06	3.00e-105	375.00
IUUC-Olo-080243	Oryza longistaminata	46.22	2.00e-90	325.00
IUUC-Ome-081230	Oryza meridionalis	43.86	5.00e-105	374.00
IUUC-Oni-082961	Oryza nivara	43.86	5.00e-105	374.00
IUUC-Opu-083189	Oryza punctata	42.98	8.00e-102	363.00
IUUC-Oru-084353	Oryza rufipogon	44.16	6.00e-103	367.00
IUUC-Osa-085458	Oryza sativa	43.86	5.00e-105	374.00
IUUC-Ola-086940	Oryzias latipes	75.05	0.00e+00	747.00
IUUC-Olu-087580	Ostreococcus lucimarinus	35.68	8.00e-64	237.00
IUUC-Oga-088703	Otolemur garnettii	93.25	0.00e+00	983.00
IUUC-Oar-089829	Ovis aries	97.22	0.00e+00	1008.00
IUUC-Ptr-090838	Pan troglodytes	99.62	0.00e+00	1036.00
IUUC-Pan-092261	Papio anubis	98.47	0.00e+00	1022.00
IUUC-Psi-093020	Pelodiscus sinensis	86.18	0.00e+00	947.00
IUUC-Pno-094858	Phaeosphaeria nodorum	38.15	1.00e-80	293.00
IUUC-Ppa-095531	Physcomitrella patens	45.14	1.00e-117	416.00
IUUC-Pfo-096812	Poecilia formosa	70.08	0.00e+00	664.00
IUUC-Pab-097805	Pongo abelii	89.08	0.00e+00	884.00
IUUC-Pop-100051	Populus trichocarpa	44.37	5.00e-105	374.00
IUUC-Pca-100152	Procavia capensis	98.83	0.00e+00	1013.00
IUUC-Ppe-101244	Prunus persica	46.00	4.00e-106	377.00
IUUC-Pva-102529	Pteropus vampyrus	95.22	0.00e+00	979.00
IUUC-Pgr-103550	Puccinia graminis	36.88	2.00e-102	365.00
IUUC-Ptt-103951	Puccinia triticina	33.33	4.00e-81	295.00
IUUC-Pte-104151	Pyrenophora teres	37.58	4.00e-80	291.00
IUUC-Pyt-104571	Pyrenophora triticirepentis	38.23	9.00e-82	297.00
IUUC-Rno-105747	Rattus norvegicus	98.82	0.00e+00	1003.00
IUUC-Sce-106418	Saccharomyces cerevisiae	33.63	1.00e-67	250.00
IUUC-Sha-107334	Sarcophilus harrisii	96.05	0.00e+00	980.00
IUUC-Sja-107794	Schizosaccharomyces japonicus	35.25	3.00e-71	262.00
IUUC-Spo-108189	Schizosaccharomyces pombe	38.12	1.00e-81	296.00
IUUC-Ssl-108550	Sclerotinia sclerotiorum	37.98	5.00e-97	348.00
IUUC-Smo-109578	Selaginella moellendorffii	46.57	1.00e-110	393.00
IUUC-Sit-110102	Setaria italica	44.34	4.00e-103	368.00
IUUC-Sly-111668	Solanum lycopersicum	46.05	6.00e-107	380.00
IUUC-Stu-111928	Solanum tuberosum	45.60	2.00e-106	379.00
IUUC-Sar-113266	Sorex araneus	86.19	0.00e+00	819.00
IUUC-Sbi-114134	Sorghum bicolor	44.12	1.00e-103	370.00
IUUC-Sre-115114	Sporisorium reilianum	41.98	3.00e-104	372.00
IUUC-Ssc-115443	Sus scrofa	99.41	0.00e+00	1007.00
IUUC-Tgu-117157	Taeniopygia guttata	90.08	0.00e+00	882.00
IUUC-Tru-118587	Takifugu rubripes	74.31	0.00e+00	726.00
IUUC-Tsy-119157	Tarsius syrichta	99.49	0.00e+00	781.00
IUUC-Tni-120427	Tetraodon nigroviridis	74.90	0.00e+00	741.00
IUUC-Tca-121368	Theobroma cacao	44.35	1.00e-106	380.00
IUUC-Tre-122074	Trichoderma reesei	37.66	8.00e-89	320.00
IUUC-Tvi-122349	Trichoderma virens	36.94	2.00e-87	316.00
IUUC-Tae-125651	Triticum aestivum	44.32	1.00e-102	367.00
IUUC-Tur-126532	Triticum urartu	43.86	1.00e-88	320.00
IUUC-Tme-126951	Tuber melanosporum	41.05	2.00e-102	365.00
IUUC-Tbe-128136	Tupaia belangeri	90.25	0.00e+00	916.00
IUUC-Ttr-129169	Tursiops truncatus	98.99	4.00e-166	577.00
IUUC-Uma-129399	Ustilago maydis	42.39	1.00e-102	367.00
IUUC-Vda-129842	Verticillium dahliae	37.98	2.00e-94	339.00
IUUC-Vpa-130440	Vicugna pacos	98.85	0.00e+00	1028.00
IUUC-Vvi-131075	Vitis vinifera	47.17	2.00e-107	383.00
IUUC-Xtr-132713	Xenopus tropicalis	49.22	2.00e-107	382.00
IUUC-Xma-133002	Xiphophorus maculatus	79.67	2.00e-171	594.00
IUUC-Yli-134569	Yarrowia lipolytica	36.04	3.00e-76	279.00
IUUC-Zma-135799	Zea mays	42.40	1.00e-100	360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence