iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118587

UUCD1 version

UUC-TaR-00450

Ensembl Protein ID

ENSTRUP00000022246.1

UniProt Accession

H2TC54; H2TC54_TAKRU

Protein Name

Uncharacterized protein

Gene Name

prpf4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000008853.1	ENSTRUT00000022337.1	ENSTRUP00000022246.1
ENSTRUG00000008853.1	ENSTRUT00000022338.1	ENSTRUP00000022247.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-38	129.8	397	435
UBD/Beta-Prp	2.20e-69	235.2	222	469

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH  + ++++f ++  +l++Gs+D+++kvW+lr  ++l 
   Q: 397  GHLKELYSVNFsPNgYHLATGSGDNSCKVWELRNRKCLY 435
           799999******77799****************999875 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdlstgkcvht 89
           ++ +i+  +fspd+++lat+s++g  k+w+v + +l+r+l gh+  v av f p++          l++++ D+ +k+w+l++ ++v  
   Q: 222  DSRPISFCHFSPDSKMLATASWSGLCKLWSVPDCSLIRTLRGHNTNVGAVVFRPQAGisldhsdvNLASCAADGSVKLWSLDSDEPVAD 310
           67799999******************************************9999998888888889*********************** PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++gh+++v  ++++psg +l ++  d+  r+wdle ++++   ++gh++ v  +++hpdg+l ++G+lD++ r+Wdl+tg+++  l+g 
   Q: 311  IEGHTERVSRVTWHPSGRFLGTTCYDNSWRLWDLEVQEEIL-HQEGHSKGVHDIHFHPDGSLAATGGLDSFGRVWDLRTGRCVVFLEG- 397
           *****************************************.********************************************99. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriW 249
           h +  ys++f++ng +l++gs d++ k+w+l++ +c++t  +h++  + vrf   ++++l++g+ D++ ++W
   Q: 398  HLKELYSVNFSPNGYHLATGSGDNSCKVWELRNRKCLYTIPAHQNLLSAVRFQpTDGHFLLTGAYDNTAKVW 469
           *****************************************************8899*************** PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

IKMSDDEDFV PVVKRSRLFY GSLEEKERER LRSEATSGST GSSAVKVGIE AGHINISSGE 60
TLELEERVSE RQQEALAAFE RRRRARQITV STDDAEVKAG LRALGEPITL FGEGPADRRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAAAAATGT CAGACGACGA GGATTTTGTT CCGGTGGTTA AAAGGAGTCG GCTTTTCTAC 60
GGAAGCCTGG AGGAGAAGGA GCGAGAGCGG CTGAGATCCG AGGCGACAAG TGGTTCAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR014906--PRP4-like
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08799--PRP4
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00500--SFM
SM00320--WD40

Gene Ontology

GO:0046540--C:U4/U6 x U5 tri-snRNP complex
GO:0030621--F:U4 snRNA binding
GO:0017070--F:U6 snRNA binding
GO:0043009--P:chordate embryonic development
GO:0000398--P:mRNA splicing, via spliceosome
GO:0060041--P:retina development in camera-type eye

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000771	Aegilops tauschii	44.86	3.00e-99	355.00
IUUC-Aml-001737	Ailuropoda melanoleuca	74.66	0.00e+00	762.00
IUUC-Atr-002828	Amborella trichopoda	42.45	5.00e-97	348.00
IUUC-Apl-003723	Anas platyrhynchos	75.05	0.00e+00	762.00
IUUC-Aca-004972	Anolis carolinensis	72.90	0.00e+00	719.00
IUUC-Aly-006531	Arabidopsis lyrata	44.32	5.00e-92	332.00
IUUC-Ath-007367	Arabidopsis thaliana	44.71	5.00e-104	371.00
IUUC-Ago-007893	Ashbya gossypii	33.24	1.00e-47	183.00
IUUC-Acl-008236	Aspergillus clavatus	38.06	5.00e-78	285.00
IUUC-Afl-008522	Aspergillus flavus	39.79	4.00e-89	322.00
IUUC-Afu-008904	Aspergillus fumigatus	38.19	8.00e-82	297.00
IUUC-Ani-009198	Aspergillus nidulans	39.08	3.00e-88	318.00
IUUC-Ang-009662	Aspergillus niger	41.47	7.00e-89	321.00
IUUC-Aor-009881	Aspergillus oryzae	39.27	3.00e-89	322.00
IUUC-Ate-010333	Aspergillus terreus	38.03	6.00e-80	291.00
IUUC-Ame-011697	Astyanax mexicanus	80.55	0.00e+00	783.00
IUUC-Bgr-012254	Blumeria graminis	39.56	1.00e-90	327.00
IUUC-Bta-012615	Bos taurus	73.87	0.00e+00	749.00
IUUC-Bci-013720	Botrytis cinerea	39.06	9.00e-90	323.00
IUUC-Bdi-014302	Brachypodium distachyon	45.07	5.00e-104	371.00
IUUC-Bol-015594	Brassica oleracea	44.84	2.00e-96	346.00
IUUC-Bra-017465	Brassica rapa	44.62	1.00e-96	347.00
IUUC-Cel-018632	Caenorhabditis elegans	45.91	1.00e-109	390.00
IUUC-Cja-019747	Callithrix jacchus	74.66	0.00e+00	765.00
IUUC-Cfa-020288	Canis familiaris	74.66	0.00e+00	763.00
IUUC-Cpo-021440	Cavia porcellus	73.33	0.00e+00	748.00
IUUC-Cre-022716	Chlamydomonas reinhardtii	47.34	1.00e-87	316.00
IUUC-Csa-023139	Chlorocebus sabaeus	79.28	2.00e-169	588.00
IUUC-Cho-024481	Choloepus hoffmanni	74.29	0.00e+00	669.00
IUUC-Cin-025106	Ciona intestinalis	58.60	3.00e-166	578.00
IUUC-Csv-026087	Ciona savignyi	58.38	4.00e-164	571.00
IUUC-Cgl-026538	Colletotrichum gloeosporioides	36.78	8.00e-81	295.00
IUUC-Cne-026793	Cryptococcus neoformans	38.75	7.00e-96	344.00
IUUC-Dre-028723	Danio rerio	80.16	0.00e+00	770.00
IUUC-Dno-029299	Dasypus novemcinctus	74.26	0.00e+00	760.00
IUUC-Dor-030345	Dipodomys ordii	55.56	1.00e-53	203.00
IUUC-Dse-031562	Dothistroma septosporum	36.38	2.00e-79	289.00
IUUC-Dme-031783	Drosophila melanogaster	55.04	3.00e-128	452.00
IUUC-Ete-032669	Echinops telfairi	75.05	0.00e+00	765.00
IUUC-Eca-033566	Equus caballus	74.66	0.00e+00	761.00
IUUC-Eeu-034524	Erinaceus europaeus	81.17	8.00e-125	440.00
IUUC-Fca-036215	Felis catus	74.66	0.00e+00	762.00
IUUC-Fal-037018	Ficedula albicollis	73.90	0.00e+00	632.00
IUUC-Fox-037936	Fusarium oxysporum	36.64	2.00e-79	290.00
IUUC-Fso-038366	Fusarium solani	39.21	1.00e-82	300.00
IUUC-Gmo-038966	Gadus morhua	70.59	3.00e-151	527.00
IUUC-Ggr-039942	Gaeumannomyces graminis	38.18	5.00e-83	301.00
IUUC-Gga-040797	Gallus gallus	75.25	0.00e+00	761.00
IUUC-Gac-042598	Gasterosteus aculeatus	75.58	0.00e+00	736.00
IUUC-Gma-044097	Glycine max	45.73	6.00e-98	351.00
IUUC-Ggo-044682	Gorilla gorilla	74.51	0.00e+00	755.00
IUUC-Hsa-045804	Homo sapiens	74.66	0.00e+00	763.00
IUUC-Hvu-047567	Hordeum vulgare	44.04	1.00e-97	349.00
IUUC-Itr-047882	Ictidomys tridecemlineatus	75.05	0.00e+00	765.00
IUUC-Kpa-049369	Komagataella pastoris	34.31	1.00e-63	236.00
IUUC-Lch-050074	Latimeria chalumnae	71.46	0.00e+00	699.00
IUUC-Lpe-051333	Leersia perrieri	44.73	2.00e-96	346.00
IUUC-Loc-052164	Lepisosteus oculatus	79.49	0.00e+00	798.00
IUUC-Lma-053088	Leptosphaeria maculans	36.78	6.00e-80	291.00
IUUC-Laf-053460	Loxodonta africana	74.66	0.00e+00	762.00
IUUC-Mcc-055859	Macaca mulatta	74.66	0.00e+00	762.00
IUUC-Meu-056134	Macropus eugenii	74.01	0.00e+00	755.00
IUUC-Mor-057251	Magnaporthe oryzae	34.23	2.00e-77	283.00
IUUC-Mpo-057375	Magnaporthe poae	41.20	1.00e-53	202.00
IUUC-Mtr-057656	Medicago truncatula	46.03	9.00e-97	347.00
IUUC-Mla-059145	Melampsora laricipopulina	39.50	3.00e-89	322.00
IUUC-Mga-059855	Meleagris gallopavo	74.26	0.00e+00	752.00
IUUC-Mvi-060372	Microbotryum violaceum	42.49	1.00e-95	343.00
IUUC-Mmr-060826	Microcebus murinus	75.05	0.00e+00	763.00
IUUC-Mdo-062748	Monodelphis domestica	74.21	0.00e+00	756.00
IUUC-Mmu-063351	Mus musculus	74.85	0.00e+00	763.00
IUUC-Mac-064846	Musa acuminata	44.93	4.00e-93	334.00
IUUC-Mpu-066006	Mustela putorius furo	74.66	0.00e+00	762.00
IUUC-Mlu-067398	Myotis lucifugus	74.46	0.00e+00	760.00
IUUC-Nfi-068399	Neosartorya fischeri	37.97	1.00e-87	317.00
IUUC-Ncr-068711	Neurospora crassa	38.33	5.00e-84	305.00
IUUC-Nle-069982	Nomascus leucogenys	74.66	0.00e+00	765.00
IUUC-Opr-070596	Ochotona princeps	74.26	0.00e+00	762.00
IUUC-Ont-072374	Oreochromis niloticus	86.60	0.00e+00	879.00
IUUC-Oan-073166	Ornithorhynchus anatinus	77.32	0.00e+00	639.00
IUUC-Ocu-074371	Oryctolagus cuniculus	74.46	0.00e+00	761.00
IUUC-Oba-075083	Oryza barthii	44.63	5.00e-96	344.00
IUUC-Obr-076405	Oryza brachyantha	45.20	6.00e-97	347.00
IUUC-Ogl-077683	Oryza glaberrima	44.63	4.00e-96	345.00
IUUC-Ogu-078486	Oryza glumaepatula	44.86	9.00e-96	343.00
IUUC-Oin-079679	Oryza indica	44.63	2.00e-98	353.00
IUUC-Olo-080243	Oryza longistaminata	45.66	1.00e-90	327.00
IUUC-Ome-081230	Oryza meridionalis	44.63	2.00e-98	353.00
IUUC-Oni-082961	Oryza nivara	44.63	2.00e-98	352.00
IUUC-Opu-083189	Oryza punctata	44.17	4.00e-95	341.00
IUUC-Oru-084353	Oryza rufipogon	44.63	3.00e-98	352.00
IUUC-Osa-085458	Oryza sativa	44.63	2.00e-98	353.00
IUUC-Ola-086940	Oryzias latipes	85.55	0.00e+00	861.00
IUUC-Olu-087580	Ostreococcus lucimarinus	38.03	6.00e-65	241.00
IUUC-Oga-088703	Otolemur garnettii	70.68	0.00e+00	716.00
IUUC-Oar-089829	Ovis aries	73.48	0.00e+00	745.00
IUUC-Ptr-090838	Pan troglodytes	74.66	0.00e+00	763.00
IUUC-Pan-092261	Papio anubis	74.46	0.00e+00	762.00
IUUC-Psi-093020	Pelodiscus sinensis	74.66	0.00e+00	765.00
IUUC-Pno-094858	Phaeosphaeria nodorum	37.00	2.00e-76	280.00
IUUC-Ppa-095531	Physcomitrella patens	45.43	3.00e-110	392.00
IUUC-Pfo-096812	Poecilia formosa	79.00	0.00e+00	786.00
IUUC-Pab-097805	Pongo abelii	67.19	0.00e+00	674.00
IUUC-Pop-100051	Populus trichocarpa	45.99	4.00e-101	362.00
IUUC-Pca-100152	Procavia capensis	74.66	0.00e+00	762.00
IUUC-Ppe-101244	Prunus persica	45.27	2.00e-105	375.00
IUUC-Pva-102529	Pteropus vampyrus	71.51	0.00e+00	720.00
IUUC-Pgr-103550	Puccinia graminis	34.69	5.00e-88	318.00
IUUC-Ptt-103951	Puccinia triticina	36.46	3.00e-66	246.00
IUUC-Pte-104151	Pyrenophora teres	36.90	5.00e-77	281.00
IUUC-Pyt-104571	Pyrenophora triticirepentis	37.55	8.00e-80	291.00
IUUC-Rno-105747	Rattus norvegicus	74.66	0.00e+00	760.00
IUUC-Sce-106418	Saccharomyces cerevisiae	38.46	1.00e-66	247.00
IUUC-Sha-107334	Sarcophilus harrisii	74.21	0.00e+00	757.00
IUUC-Sja-107794	Schizosaccharomyces japonicus	36.47	8.00e-66	244.00
IUUC-Spo-108189	Schizosaccharomyces pombe	36.85	4.00e-73	268.00
IUUC-Ssl-108550	Sclerotinia sclerotiorum	38.62	2.00e-88	320.00
IUUC-Smo-108924	Selaginella moellendorffii	44.84	6.00e-103	367.00
IUUC-Sit-110102	Setaria italica	43.02	2.00e-96	346.00
IUUC-Sly-111668	Solanum lycopersicum	46.53	5.00e-104	371.00
IUUC-Stu-111928	Solanum tuberosum	46.30	1.00e-103	370.00
IUUC-Sar-113266	Sorex araneus	64.44	0.00e+00	639.00
IUUC-Sbi-114134	Sorghum bicolor	43.49	2.00e-97	349.00
IUUC-Sre-115114	Sporisorium reilianum	40.71	1.00e-94	340.00
IUUC-Ssc-115443	Sus scrofa	74.66	0.00e+00	762.00
IUUC-Tgu-117157	Taeniopygia guttata	74.85	0.00e+00	723.00
IUUC-Tsy-119157	Tarsius syrichta	77.26	0.00e+00	642.00
IUUC-Tni-120427	Tetraodon nigroviridis	93.16	0.00e+00	900.00
IUUC-Tca-121368	Theobroma cacao	46.46	2.00e-107	383.00
IUUC-Tre-122074	Trichoderma reesei	37.94	7.00e-80	291.00
IUUC-Tvi-122349	Trichoderma virens	36.70	4.00e-78	285.00
IUUC-Tae-125651	Triticum aestivum	44.86	2.00e-99	356.00
IUUC-Tur-126532	Triticum urartu	43.86	2.00e-88	319.00
IUUC-Tme-126951	Tuber melanosporum	40.48	5.00e-92	331.00
IUUC-Tbe-128136	Tupaia belangeri	67.39	0.00e+00	666.00
IUUC-Ttr-129169	Tursiops truncatus	76.08	2.00e-120	425.00
IUUC-Uma-129399	Ustilago maydis	39.39	7.00e-96	344.00
IUUC-Vda-129842	Verticillium dahliae	37.56	8.00e-82	297.00
IUUC-Vpa-130440	Vicugna pacos	74.46	0.00e+00	761.00
IUUC-Vvi-131075	Vitis vinifera	46.19	3.00e-105	376.00
IUUC-Xtr-132713	Xenopus tropicalis	42.31	1.00e-86	313.00
IUUC-Xma-133002	Xiphophorus maculatus	88.95	0.00e+00	664.00
IUUC-Yli-134569	Yarrowia lipolytica	36.95	1.00e-73	270.00
IUUC-Zma-135799	Zea mays	41.54	3.00e-96	345.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence