iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052333

Ensembl Protein ID

ENSLOCP00000016619.1

UniProt Accession

W5N7L0; W5N7L0_LEPOC

Genbank Protein ID

ENSLOCP00000016619

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01031846

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000013469.1	ENSLOCT00000016649.1	ENSLOCP00000016619.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-18	64.7	1385	1425
UBD/Beta-Prp	1.40e-49	169.1	1342	1547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd..tllvsGsdDgtikvWDlrtgvll 36
           gHt +v+cl     ++   +l +G+ D+ti++++++t+ ++
   Q: 1385 GHTTKVNCLMVsqgPGmpVYLYTGASDHTIRCYNVKTFECV 1425
           8********88999545689******************997 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqcle 130
            ++gh+a+v+++++++   +l t+s D+t++ ++l t+kcv +++gh+ +v +l +s+      +l +G +d tir+++++t +c+e
   Q: 1342 AFEGHQAAVNSMQIHNG--LLYTCSGDKTVRAFSLVTRKCVAVFEGHTTKVNCLMVSQgpgMPVYLYTGASDHTIRCYNVKTFECVE 1426
           689**************..9**************************************9644499*********************9 PP
   S: 131  etlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtgecv 215
               +  ++ +++++h+  ++l +G +++tv   +lkt+k l+ ++    ++v +++  ++g  + l+ gs+d t+ + d ++g  +
   Q: 1427 ----QFCQLDRVLCLHSRWKVLYAGLANGTVVSISLKTNKQLDVFECHAPRAVSCIATAQEGarRILLVGSYDCTISVRDAKSGLLL 1509
           ....333344666777777**************************997888999999988889899********************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgd 255
           rtl+ght++v+++++   ++++ sgssD+s+  +++ +g+
   Q: 1510 RTLEGHTKTVLCMKVV--NDLVFSGSSDQSVHAHNIHTGE 1547
           ****************..9*****************9987 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGKERKCILC HIVYNSKKEM DEHMRSMLHH RELENLKGRD CDHECRVCGV EVVGLTAYAN 60
HISSPLHKSA VKARDREDEG KDECEEEYFD RDLIQLIEQR REQSRREKEE AAKASLNEEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCCAAGG TGATGGCTTG ATGTCTATCT AGAAGCTCCA AGATGGGAAA AGAACGGAAG 60
TGCATTCTCT GCCACATCGT TTACAACTCA AAGAAGGTAA CACAACTGTG AAAAGAATAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR018391--PQQ_beta_propeller_repeat
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013087--Znf_C2H2_type

PROSITE

PS50294--WD_REPEATS_REGION
PS00028--ZINC_FINGER_C2H2_1

Pfam

PF00400--WD40

SMART

SM00564--PQQ
SM00320--WD40
SM00355--ZnF_C2H2

Gene Ontology

GO:0046872--F:metal ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001928	Ailuropoda melanoleuca	43.24	0.00e+00	1148.00
IUUC-Apl-003674	Anas platyrhynchos	69.27	0.00e+00	736.00
IUUC-Aca-005018	Anolis carolinensis	68.91	0.00e+00	726.00
IUUC-Ame-011431	Astyanax mexicanus	73.08	0.00e+00	688.00
IUUC-Bta-013436	Bos taurus	56.26	0.00e+00	850.00
IUUC-Cfa-020278	Canis familiaris	42.69	3.00e-136	480.00
IUUC-Cpo-022278	Cavia porcellus	68.41	0.00e+00	739.00
IUUC-Csa-023115	Chlorocebus sabaeus	57.45	0.00e+00	849.00
IUUC-Cho-024829	Choloepus hoffmanni	34.34	1.00e-137	484.00
IUUC-Dre-028112	Danio rerio	71.95	0.00e+00	667.00
IUUC-Dno-029127	Dasypus novemcinctus	55.76	0.00e+00	832.00
IUUC-Dor-030367	Dipodomys ordii	61.42	0.00e+00	651.00
IUUC-Ete-032500	Echinops telfairi	62.59	0.00e+00	649.00
IUUC-Eca-034319	Equus caballus	44.48	0.00e+00	1225.00
IUUC-Eeu-034754	Erinaceus europaeus	63.19	2.00e-151	530.00
IUUC-Fca-036181	Felis catus	43.10	0.00e+00	1119.00
IUUC-Fal-036865	Ficedula albicollis	66.90	0.00e+00	696.00
IUUC-Gmo-039227	Gadus morhua	73.73	3.00e-166	578.00
IUUC-Gga-041178	Gallus gallus	69.83	0.00e+00	740.00
IUUC-Gac-042209	Gasterosteus aculeatus	66.99	4.00e-170	591.00
IUUC-Ggo-044636	Gorilla gorilla	67.60	0.00e+00	755.00
IUUC-Hsa-045949	Homo sapiens	56.39	0.00e+00	845.00
IUUC-Itr-048628	Ictidomys tridecemlineatus	56.67	0.00e+00	867.00
IUUC-Lch-049753	Latimeria chalumnae	45.51	0.00e+00	1223.00
IUUC-Laf-053530	Loxodonta africana	43.94	0.00e+00	1211.00
IUUC-Mcc-054664	Macaca mulatta	68.01	0.00e+00	762.00
IUUC-Meu-056609	Macropus eugenii	48.53	0.00e+00	659.00
IUUC-Mga-059632	Meleagris gallopavo	43.59	0.00e+00	1154.00
IUUC-Mmr-060742	Microcebus murinus	52.80	0.00e+00	998.00
IUUC-Mdo-061831	Monodelphis domestica	66.73	0.00e+00	741.00
IUUC-Mmu-064055	Mus musculus	73.64	0.00e+00	719.00
IUUC-Mpu-066458	Mustela putorius furo	45.18	0.00e+00	1238.00
IUUC-Mlu-067767	Myotis lucifugus	69.56	0.00e+00	757.00
IUUC-Nle-069728	Nomascus leucogenys	67.83	0.00e+00	761.00
IUUC-Opr-070914	Ochotona princeps	64.33	0.00e+00	722.00
IUUC-Ont-072353	Oreochromis niloticus	48.13	0.00e+00	941.00
IUUC-Ocu-073827	Oryctolagus cuniculus	55.17	0.00e+00	812.00
IUUC-Ola-087573	Oryzias latipes	70.39	2.00e-163	569.00
IUUC-Oga-088664	Otolemur garnettii	55.57	0.00e+00	847.00
IUUC-Oar-090256	Ovis aries	35.69	8.00e-114	405.00
IUUC-Ptr-090884	Pan troglodytes	67.83	0.00e+00	764.00
IUUC-Pan-091779	Papio anubis	57.74	0.00e+00	850.00
IUUC-Psi-093267	Pelodiscus sinensis	83.58	9.00e-151	525.00
IUUC-Pma-094414	Petromyzon marinus	43.69	7.00e-48	186.00
IUUC-Pfo-097009	Poecilia formosa	67.15	3.00e-162	566.00
IUUC-Pca-100820	Procavia capensis	35.74	3.00e-156	546.00
IUUC-Pva-103044	Pteropus vampyrus	81.79	0.00e+00	661.00
IUUC-Rno-105960	Rattus norvegicus	65.81	0.00e+00	718.00
IUUC-Sar-113018	Sorex araneus	62.34	0.00e+00	646.00
IUUC-Ssc-115278	Sus scrofa	56.35	0.00e+00	846.00
IUUC-Tgu-117231	Taeniopygia guttata	44.98	0.00e+00	1171.00
IUUC-Tru-118472	Takifugu rubripes	47.27	0.00e+00	794.00
IUUC-Tsy-118877	Tarsius syrichta	82.55	1.00e-177	617.00
IUUC-Tni-119881	Tetraodon nigroviridis	48.59	0.00e+00	851.00
IUUC-Tbe-127499	Tupaia belangeri	65.54	7.00e-143	502.00
IUUC-Ttr-128962	Tursiops truncatus	72.59	0.00e+00	714.00
IUUC-Vpa-130089	Vicugna pacos	46.35	3.00e-104	374.00
IUUC-Xtr-132940	Xenopus tropicalis	43.63	0.00e+00	1112.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence