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Tag Content
UUCD2 ID IUUC-Cpo-021910
UUCD1 version UUC-CaP-01075
Ensembl Protein ID ENSCPOP00000003545.2
UniProt Accession H0V203; H0V203_CAVPO
Genbank Protein ID ENSCPOP00000003545
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAKN02004994
Gene Name USP33
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000003926.3 ENSCPOT00000003970.2 ENSCPOP00000003545.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.60e-88 295.6 154 682
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGlkN+gNtCYmN++LQ+Lsn+p+l++++l+     +   +++++k +++ks+ kl++elw ks+ ++v p++l++ +k++++ f+gy+
   Q: 154  TGLKNIGNTCYMNAALQALSNCPPLTQFFLD-----CGGLARTDKKPAICKSYLKLMTELWhKSRPGSVVPTNLFQGIKTVNPTFRGYS 237
           7******************************.....999999*******************99************************** PP
   S: 89   qqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsde........................................ 129
           qqDaqEfl++l+d l+eelk+        +++ + ee+ e+dks++  +                                        
   Q: 238  QQDAQEFLRCLMDLLHEELKEqvmeveedHQTITSEETIEDDKSQS--Dvdfqscdscsssdkaesengprgfpednnettmliqdeen 324
           *******************887776664433333333334443333..2569************************************* PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 325  nseiskdwqkekmcskmnkvnsegdldkdrdsvsetvdlnnqetvkvqihgrasdyitdvhlnelstpqilpsneginprlstsppksg 413
           ***************************************************************************************** PP
   S: 130  ..................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke............... 185
                             +++k++kk++s+isd+F+g++ s+++cl+cd+vs++ e+f+dlslp+pgke+ +k+               
   Q: 414  nlwpglapphkkaqsaspKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLhssshptsivkagsc 502
           ******************9**************************************************99888*************** PP
   S: 186  ..................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfs 240
                                             +lqdcL++f++++el+g+n+y cekckk+++ +k +k++k+Pev +l  k+++  
   Q: 503  geayapqgwiaffmeyvkrfvvscvpswfwgpvvTLQDCLAAFFARDELKGDNMYRCEKCKKLRNGVKFCKVQKFPEVQTLXKKKIKQ- 590
           **************************************************************************************54. PP
   S: 241  eeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgs 328
            + +  ++i +  + +++L+++p  +s   k    +++  i ++++     +GHY+ay++n+ +k W++fdD++Vtev+e++v++   +
   Q: 591  IYCWLLKQIRRTSTHKETLNVEPNIVSYPIK---MYIFFFITIMIYLPLYIGGHYIAYCRNNLNKlWYEFDDQSVTEVSESTVQN---A 673
           556999999999999999****977774444...6999999********************88889*******************...* PP
   S: 329  taYvlfYkr 337
           +aYvlfY++
   Q: 674  EAYVLFYRK 682
           *******98 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
MSTFRNHCPH LDSVGEITKE DLIQKSHGTC QDCKVRGPNL WACLENRCSY VGCGESQVDH 60
STIHSQDTKH YLTVNLTTLR VWCYACSKEV FLDRKLGTQT SLPHVRQPQQ IQENSVQDFK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-021910|DUB,USP|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCAACTT TTCGAAATCA TTGTCCACAT TTGGATTCAG TTGGTGAAAT AACAAAAGAA 60
GATTTGATAC AAAAATCACA TGTAAGATAT AGTCTTGCTT AAATTATATT CACATTTTCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-021910|DUB,USP|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005776--C:autophagosome
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0009267--P:cellular response to starvation
GO:0051298--P:centrosome duplication
GO:0032091--P:negative regulation of protein binding
GO:0032092--P:positive regulation of protein binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001742 Ailuropoda melanoleuca 89.41 0.00e+00 1627.00
IUUC-Apl-003987 Anas platyrhynchos 75.96 0.00e+00 1338.00
IUUC-Aca-004713 Anolis carolinensis 72.02 0.00e+00 1302.00
IUUC-Ame-010697 Astyanax mexicanus 70.16 0.00e+00 724.00
IUUC-Bta-013132 Bos taurus 88.84 0.00e+00 1612.00
IUUC-Cja-018811 Callithrix jacchus 89.05 0.00e+00 1627.00
IUUC-Cfa-021158 Canis familiaris 88.86 0.00e+00 1612.00
IUUC-Csa-023130 Chlorocebus sabaeus 89.81 0.00e+00 1637.00
IUUC-Cho-024383 Choloepus hoffmanni 76.72 0.00e+00 630.00
IUUC-Dre-028639 Danio rerio 65.46 0.00e+00 1125.00
IUUC-Dno-029416 Dasypus novemcinctus 87.09 0.00e+00 1548.00
IUUC-Ete-032994 Echinops telfairi 77.48 0.00e+00 827.00
IUUC-Eca-034248 Equus caballus 89.50 0.00e+00 1623.00
IUUC-Eeu-035357 Erinaceus europaeus 69.77 0.00e+00 1139.00
IUUC-Fca-036013 Felis catus 86.76 0.00e+00 1566.00
IUUC-Fal-037509 Ficedula albicollis 75.16 0.00e+00 1342.00
IUUC-Gmo-038944 Gadus morhua 60.95 0.00e+00 1065.00
IUUC-Gga-040647 Gallus gallus 74.86 0.00e+00 1319.00
IUUC-Gac-041752 Gasterosteus aculeatus 63.88 0.00e+00 1123.00
IUUC-Hsa-045694 Homo sapiens 89.05 0.00e+00 1619.00
IUUC-Itr-049041 Ictidomys tridecemlineatus 89.17 0.00e+00 1597.00
IUUC-Lch-050400 Latimeria chalumnae 64.99 0.00e+00 1140.00
IUUC-Loc-052616 Lepisosteus oculatus 67.76 0.00e+00 1199.00
IUUC-Laf-053493 Loxodonta africana 87.96 0.00e+00 1608.00
IUUC-Mcc-055542 Macaca mulatta 89.92 0.00e+00 1640.00
IUUC-Meu-056645 Macropus eugenii 67.10 0.00e+00 1142.00
IUUC-Mga-060019 Meleagris gallopavo 74.67 0.00e+00 1114.00
IUUC-Mmr-061241 Microcebus murinus 86.09 0.00e+00 1578.00
IUUC-Mmu-063786 Mus musculus 85.98 0.00e+00 1566.00
IUUC-Mpu-065772 Mustela putorius furo 87.60 0.00e+00 1319.00
IUUC-Mlu-067732 Myotis lucifugus 87.25 0.00e+00 1586.00
IUUC-Nle-069528 Nomascus leucogenys 88.61 0.00e+00 1630.00
IUUC-Opr-070606 Ochotona princeps 83.79 0.00e+00 1443.00
IUUC-Ont-071495 Oreochromis niloticus 65.41 0.00e+00 1135.00
IUUC-Oan-073695 Ornithorhynchus anatinus 83.76 0.00e+00 928.00
IUUC-Ocu-074457 Oryctolagus cuniculus 85.56 0.00e+00 1566.00
IUUC-Ola-086739 Oryzias latipes 63.53 0.00e+00 1147.00
IUUC-Oga-088720 Otolemur garnettii 89.25 0.00e+00 1640.00
IUUC-Oar-089921 Ovis aries 88.84 0.00e+00 1615.00
IUUC-Ptr-090526 Pan troglodytes 89.16 0.00e+00 1623.00
IUUC-Pan-092396 Papio anubis 89.63 0.00e+00 1632.00
IUUC-Psi-092971 Pelodiscus sinensis 76.94 0.00e+00 1410.00
IUUC-Pfo-097415 Poecilia formosa 64.43 0.00e+00 1134.00
IUUC-Pab-098740 Pongo abelii 89.59 0.00e+00 1654.00
IUUC-Pca-100598 Procavia capensis 72.85 0.00e+00 774.00
IUUC-Pva-102820 Pteropus vampyrus 83.69 0.00e+00 1325.00
IUUC-Rno-104894 Rattus norvegicus 86.43 0.00e+00 1588.00
IUUC-Sha-107244 Sarcophilus harrisii 71.77 0.00e+00 1256.00
IUUC-Sar-113665 Sorex araneus 86.11 0.00e+00 1590.00
IUUC-Ssc-115793 Sus scrofa 86.67 0.00e+00 1546.00
IUUC-Tgu-117487 Taeniopygia guttata 76.19 0.00e+00 1313.00
IUUC-Tru-117694 Takifugu rubripes 63.43 0.00e+00 1142.00
IUUC-Tsy-119598 Tarsius syrichta 77.28 0.00e+00 1333.00
IUUC-Tni-120189 Tetraodon nigroviridis 61.49 0.00e+00 1071.00
IUUC-Tbe-128125 Tupaia belangeri 85.36 1.00e-110 394.00
IUUC-Ttr-128269 Tursiops truncatus 85.32 0.00e+00 1484.00
IUUC-Vpa-130598 Vicugna pacos 87.76 0.00e+00 1576.00
IUUC-Xtr-132044 Xenopus tropicalis 69.54 0.00e+00 1197.00
Created Date 25-Jun-2017

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