iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052570

Ensembl Protein ID

ENSLOCP00000003995.1

UniProt Accession

W5M6I7; W5M6I7_LEPOC

Genbank Protein ID

ENSLOCP00000003995

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01024162

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000003343.1	ENSLOCT00000004003.1	ENSLOCP00000003995.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-07	31.3	365	404
UBD/Alpha-Helix/UBA	5.90e-06	26.4	861	895

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl  w    + +s  + CP Cr
   Q: 365  CKICAENDKD-VKIEPCGHLMCTSCLTSW----Q-ESEGQGCPFCR 404
           99********.******************....5.555555****8 PP

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraannnleaAveyL 38
           ++ +e l+++G++ +++++aL+ a nn+e+A + L
   Q: 861  NSEIEHLMSQGYSYQDIQKALLIAQNNIEMAKNIL 895
           6789***************************9988 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MAGNLKKGGG LIGMMKDAFQ PHHHHLHSHH PPGAVDKRTV EKCWKLMDKV VRLCQNPKLA 60
LKNSPPYILD LLPDTYQHLR TILSRYEGKM ETLGENEYFR VFMENLTKKT KQTISLFKEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAAAGCGGA AAAGGATGTG CTTAGAAAAA CTGGGGCCGC ACTCGCGGGA GGGGGAGACA 60
GAAGGCGGTG TTTATTTTTC CTAATTTATT TCTTTACGTT AGTTTTTTTT TTGTGTAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
PF00627--UBA

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002357	Ailuropoda melanoleuca	72.96	0.00e+00	1105.00
IUUC-Apl-004041	Anas platyrhynchos	73.36	0.00e+00	1123.00
IUUC-Aca-004899	Anolis carolinensis	72.08	0.00e+00	1074.00
IUUC-Ame-010746	Astyanax mexicanus	75.75	0.00e+00	797.00
IUUC-Bta-012759	Bos taurus	71.51	0.00e+00	1125.00
IUUC-Cel-018674	Caenorhabditis elegans	55.41	2.00e-133	469.00
IUUC-Cja-019207	Callithrix jacchus	71.17	0.00e+00	1129.00
IUUC-Cfa-020897	Canis familiaris	70.68	0.00e+00	1113.00
IUUC-Cpo-021453	Cavia porcellus	71.89	0.00e+00	1112.00
IUUC-Csa-023136	Chlorocebus sabaeus	71.70	0.00e+00	1132.00
IUUC-Cho-024282	Choloepus hoffmanni	63.11	0.00e+00	930.00
IUUC-Cin-025574	Ciona intestinalis	71.28	2.00e-178	618.00
IUUC-Csv-025938	Ciona savignyi	69.37	5.00e-173	600.00
IUUC-Dre-027644	Danio rerio	80.53	0.00e+00	1199.00
IUUC-Dno-030025	Dasypus novemcinctus	70.89	0.00e+00	1089.00
IUUC-Dme-032213	Drosophila melanogaster	74.55	0.00e+00	647.00
IUUC-Eca-033900	Equus caballus	71.62	0.00e+00	1106.00
IUUC-Eeu-035142	Erinaceus europaeus	72.96	0.00e+00	781.00
IUUC-Fca-035455	Felis catus	70.86	0.00e+00	1136.00
IUUC-Fal-037182	Ficedula albicollis	90.10	0.00e+00	840.00
IUUC-Gmo-038698	Gadus morhua	92.67	0.00e+00	922.00
IUUC-Gga-040438	Gallus gallus	72.82	0.00e+00	1137.00
IUUC-Gac-042166	Gasterosteus aculeatus	80.48	0.00e+00	1017.00
IUUC-Ggo-045618	Gorilla gorilla	71.61	0.00e+00	1132.00
IUUC-Hsa-046177	Homo sapiens	71.72	0.00e+00	1131.00
IUUC-Itr-048795	Ictidomys tridecemlineatus	78.35	0.00e+00	800.00
IUUC-Lch-050095	Latimeria chalumnae	74.32	0.00e+00	1140.00
IUUC-Laf-054008	Loxodonta africana	71.00	0.00e+00	1142.00
IUUC-Mcc-054676	Macaca mulatta	71.70	0.00e+00	1134.00
IUUC-Mga-059239	Meleagris gallopavo	73.88	0.00e+00	1165.00
IUUC-Mmr-060907	Microcebus murinus	70.29	0.00e+00	1120.00
IUUC-Mdo-062595	Monodelphis domestica	72.87	0.00e+00	1106.00
IUUC-Mmu-063725	Mus musculus	71.29	0.00e+00	1159.00
IUUC-Mpu-066771	Mustela putorius furo	70.79	0.00e+00	1136.00
IUUC-Mlu-067206	Myotis lucifugus	75.34	0.00e+00	866.00
IUUC-Nle-069285	Nomascus leucogenys	70.02	0.00e+00	1066.00
IUUC-Opr-071026	Ochotona princeps	71.05	0.00e+00	1094.00
IUUC-Ont-071954	Oreochromis niloticus	76.96	0.00e+00	1180.00
IUUC-Ocu-074657	Oryctolagus cuniculus	72.50	0.00e+00	1089.00
IUUC-Ola-087165	Oryzias latipes	76.19	0.00e+00	1173.00
IUUC-Oga-088198	Otolemur garnettii	73.82	0.00e+00	949.00
IUUC-Oar-090258	Ovis aries	71.79	0.00e+00	1077.00
IUUC-Ptr-090710	Pan troglodytes	71.72	0.00e+00	1131.00
IUUC-Pan-092785	Papio anubis	71.70	0.00e+00	1130.00
IUUC-Pfo-096990	Poecilia formosa	74.07	0.00e+00	1098.00
IUUC-Pab-098526	Pongo abelii	71.69	0.00e+00	1129.00
IUUC-Pva-102352	Pteropus vampyrus	86.97	0.00e+00	828.00
IUUC-Rno-105876	Rattus norvegicus	71.22	0.00e+00	1154.00
IUUC-Sha-107588	Sarcophilus harrisii	70.80	0.00e+00	962.00
IUUC-Sar-112959	Sorex araneus	70.66	0.00e+00	1072.00
IUUC-Ssc-115261	Sus scrofa	71.26	0.00e+00	1155.00
IUUC-Tgu-116580	Taeniopygia guttata	72.16	0.00e+00	1089.00
IUUC-Tru-118731	Takifugu rubripes	77.00	0.00e+00	1186.00
IUUC-Tsy-118982	Tarsius syrichta	61.86	0.00e+00	674.00
IUUC-Tni-120725	Tetraodon nigroviridis	73.12	0.00e+00	1115.00
IUUC-Tbe-128018	Tupaia belangeri	81.10	0.00e+00	957.00
IUUC-Ttr-128927	Tursiops truncatus	72.62	0.00e+00	1164.00
IUUC-Vpa-130369	Vicugna pacos	70.89	0.00e+00	1047.00
IUUC-Xtr-132474	Xenopus tropicalis	68.64	0.00e+00	1057.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence