iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045211

Ensembl Protein ID

ENSGGOP00000008374.2

UniProt Accession

G3QZQ8; G3QZQ8_GORGO

Protein Name

Uncharacterized protein

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000008566.2	ENSGGOT00000008605.2	ENSGGOP00000008374.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.70e-13	50.7	369	423

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v++lydy +q+ deL++++G+ +l +  ee ++gW++g+   +g+ Gl P+n+ve 
   Q: 369  RVRALYDYAGQEADELSFRAGEELLKM-SEEDEQGWCQGQ-LQSGRIGLYPANYVEC 423
           689********************9999.999********7.99************86 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

DTMAPEEDAG GEALGGSFWE AGNYRRTVQR VEDGHRLCGD LVSCFQERAR IEKAYGQQLA 60
DWARKWRGTV EKGPQYGTLE KAWHAFFTAA ERLSALHLEV REKLQGQDSE RVRAWQRGAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCGGGCCC AGGAGCGGCA GGACTCGGGT CGGAGCGTGG CCAGACCCCC ACCCGCCGAG 60
GGGCCCAGGG AGGACGCGGT GAGTGCCCTG GAGGGGACGC GCGGGTAGGC GGCGGCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	96.11	0.00e+00	657.00
IUUC-Apl-003211	Anas platyrhynchos	64.63	2.00e-180	625.00
IUUC-Aca-004256	Anolis carolinensis	64.40	7.00e-178	616.00
IUUC-Ame-011049	Astyanax mexicanus	60.81	6.00e-154	537.00
IUUC-Bta-013322	Bos taurus	91.95	0.00e+00	772.00
IUUC-Cja-018907	Callithrix jacchus	98.11	0.00e+00	819.00
IUUC-Cfa-021126	Canis familiaris	95.99	0.00e+00	802.00
IUUC-Cpo-021491	Cavia porcellus	93.87	0.00e+00	796.00
IUUC-Csa-023107	Chlorocebus sabaeus	99.53	0.00e+00	826.00
IUUC-Dre-027933	Danio rerio	60.59	3.00e-147	514.00
IUUC-Dno-029002	Dasypus novemcinctus	95.05	0.00e+00	768.00
IUUC-Eca-033824	Equus caballus	95.05	0.00e+00	798.00
IUUC-Eeu-035122	Erinaceus europaeus	86.12	2.00e-173	601.00
IUUC-Fca-036420	Felis catus	95.99	0.00e+00	814.00
IUUC-Fal-037277	Ficedula albicollis	64.55	0.00e+00	631.00
IUUC-Gga-040941	Gallus gallus	64.77	3.00e-180	624.00
IUUC-Gac-041374	Gasterosteus aculeatus	62.44	2.00e-138	485.00
IUUC-Hsa-046053	Homo sapiens	99.53	0.00e+00	826.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	95.75	0.00e+00	806.00
IUUC-Loc-052808	Lepisosteus oculatus	62.41	2.00e-157	548.00
IUUC-Laf-054211	Loxodonta africana	94.34	0.00e+00	761.00
IUUC-Mcc-055044	Macaca mulatta	99.53	0.00e+00	826.00
IUUC-Mga-059216	Meleagris gallopavo	64.71	1.00e-180	625.00
IUUC-Mmr-061172	Microcebus murinus	98.58	0.00e+00	828.00
IUUC-Mdo-062600	Monodelphis domestica	88.21	0.00e+00	770.00
IUUC-Mmu-063218	Mus musculus	94.10	0.00e+00	794.00
IUUC-Mpu-066819	Mustela putorius furo	95.52	0.00e+00	658.00
IUUC-Mlu-067597	Myotis lucifugus	92.38	0.00e+00	796.00
IUUC-Nle-069195	Nomascus leucogenys	98.82	0.00e+00	820.00
IUUC-Opr-071050	Ochotona princeps	95.53	0.00e+00	782.00
IUUC-Ont-071612	Oreochromis niloticus	55.25	2.00e-141	495.00
IUUC-Oan-073256	Ornithorhynchus anatinus	88.26	0.00e+00	743.00
IUUC-Ocu-074653	Oryctolagus cuniculus	96.23	0.00e+00	779.00
IUUC-Oga-089040	Otolemur garnettii	95.99	0.00e+00	816.00
IUUC-Oar-089918	Ovis aries	95.61	0.00e+00	786.00
IUUC-Ptr-091307	Pan troglodytes	99.53	0.00e+00	826.00
IUUC-Pan-092512	Papio anubis	99.53	0.00e+00	826.00
IUUC-Pfo-096881	Poecilia formosa	61.12	1.00e-153	536.00
IUUC-Pab-098620	Pongo abelii	99.53	0.00e+00	826.00
IUUC-Pva-102464	Pteropus vampyrus	92.69	0.00e+00	776.00
IUUC-Rno-106091	Rattus norvegicus	93.63	0.00e+00	791.00
IUUC-Sha-107474	Sarcophilus harrisii	88.92	0.00e+00	766.00
IUUC-Ssc-116128	Sus scrofa	95.28	0.00e+00	806.00
IUUC-Tgu-117511	Taeniopygia guttata	61.76	3.00e-176	611.00
IUUC-Tru-118005	Takifugu rubripes	60.63	8.00e-141	493.00
IUUC-Tni-119851	Tetraodon nigroviridis	65.46	6.00e-141	493.00
IUUC-Ttr-129313	Tursiops truncatus	95.28	0.00e+00	810.00
IUUC-Vpa-130760	Vicugna pacos	96.17	2.00e-100	358.00
IUUC-Xtr-132697	Xenopus tropicalis	57.18	9.00e-141	493.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence