iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048216

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01083688

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000015533.2	ENSSTOT00000015539.2	ENSSTOP00000013909.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-68	232.0	198	576

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 198  GLINKGNWCYINATLQALVACPPMYHLMKF-LPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkvvrdirpgaAFEPT 284
           9**************************999.333333.345799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsdeaeekkkkknk... 139
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+ +                  +++  +eee+e++   s++++e+   +nk   
   Q: 285  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLSlkkllspndekltvsngPRSHLADEEEQEERGGGSEDEWEQVGPRNKssv 373
           *9999999999966599********************5556677776677776666455555555555555555555555444444445 PP
   S: 140  ........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekk 220
                   ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k k+++e +++
   Q: 374  trqadfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKTKQEVEISRR 454
           55555666***********9.688999999*******************99...****************8....99999********* PP
   S: 221  lklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYvayvknekgk 305
           ++l+klP+vL+lhLkRf ++++++++ k+ k++++p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY+++v +   +
   Q: 455  VTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIDYPVDLEISKELLSPGVKNKNfkcHRTYRLFAVVYHHGsSATGGHYTTDVFQIGLN 542
           *******************9998886.****************999988777777879***************************8777 PP
   S: 306  .WllfdDskVtevkeeevleetg.staYvlfYkr 337
            Wl++dD++V++v++ +v++  + +taY+l+Y+r
   Q: 543  gWLRIDDQTVKVVTQYQVVKPAAeRTAYLLYYRR 576
           7*****************997778********98 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MDFISDTVPD GPFPGALDGD ARTAGQPKGC HGTDFEQPCL PAGSLLRTAV APPYSGTDTT 60
ENLGVANGQI LESSGEGTAA NGVELHTVES IDLDPVKPES VSPPADSTVS APGTIPISQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCCAGG AGAAGGTCAA GGTAAGGTGG ATTGCAAAAG CAAGAGAGTG TGACTGTCAG 60
GAAGCTGGGA GATGTCTCTT CTAGCAGGGT GACATTTGAA CTAGAGTTTT CAGGCAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.03	4.00e-45	176.00
IUUC-Aml-001584	Ailuropoda melanoleuca	88.68	0.00e+00	978.00
IUUC-Atr-002927	Amborella trichopoda	35.48	7.00e-58	218.00
IUUC-Apl-003988	Anas platyrhynchos	82.76	0.00e+00	914.00
IUUC-Aca-004461	Anolis carolinensis	91.62	3.00e-163	567.00
IUUC-Aly-006038	Arabidopsis lyrata	35.90	3.00e-54	205.00
IUUC-Ath-007328	Arabidopsis thaliana	35.64	7.00e-53	201.00
IUUC-Ago-007717	Ashbya gossypii	30.11	3.00e-44	173.00
IUUC-Acl-008188	Aspergillus clavatus	34.59	3.00e-63	236.00
IUUC-Afl-008456	Aspergillus flavus	38.08	3.00e-48	185.00
IUUC-Afu-009067	Aspergillus fumigatus	35.31	8.00e-65	241.00
IUUC-Ani-009483	Aspergillus nidulans	32.90	3.00e-61	229.00
IUUC-Ang-009639	Aspergillus niger	36.25	6.00e-61	228.00
IUUC-Aor-010040	Aspergillus oryzae	35.27	4.00e-60	226.00
IUUC-Ate-010310	Aspergillus terreus	34.48	7.00e-62	231.00
IUUC-Ame-011012	Astyanax mexicanus	74.20	3.00e-164	572.00
IUUC-Bgr-012311	Blumeria graminis	34.59	5.00e-43	169.00
IUUC-Bta-013299	Bos taurus	88.70	0.00e+00	934.00
IUUC-Bci-013783	Botrytis cinerea	37.76	1.00e-59	224.00
IUUC-Bdi-015039	Brachypodium distachyon	33.01	4.00e-50	192.00
IUUC-Bol-015806	Brassica oleracea	37.18	5.00e-62	231.00
IUUC-Bra-017076	Brassica rapa	37.18	2.00e-62	233.00
IUUC-Cja-018715	Callithrix jacchus	89.18	0.00e+00	1003.00
IUUC-Cfa-020194	Canis familiaris	90.39	0.00e+00	1019.00
IUUC-Cpo-022272	Cavia porcellus	80.69	0.00e+00	848.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.78	1.00e-34	141.00
IUUC-Csa-023310	Chlorocebus sabaeus	90.38	0.00e+00	1019.00
IUUC-Cho-024966	Choloepus hoffmanni	74.17	4.00e-175	607.00
IUUC-Cin-025616	Ciona intestinalis	47.61	1.00e-104	373.00
IUUC-Csv-026043	Ciona savignyi	46.43	6.00e-98	350.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	35.22	4.00e-47	183.00
IUUC-Cne-026962	Cryptococcus neoformans	34.70	1.00e-48	188.00
IUUC-Cme-027113	Cyanidioschyzon merolae	31.62	1.00e-39	157.00
IUUC-Dre-028072	Danio rerio	77.68	0.00e+00	714.00
IUUC-Dno-029489	Dasypus novemcinctus	90.75	0.00e+00	1046.00
IUUC-Dor-031068	Dipodomys ordii	75.54	8.00e-144	504.00
IUUC-Dse-031553	Dothistroma septosporum	36.34	4.00e-56	213.00
IUUC-Dme-031759	Drosophila melanogaster	42.04	1.00e-83	305.00
IUUC-Ete-032549	Echinops telfairi	82.52	0.00e+00	710.00
IUUC-Eca-033380	Equus caballus	89.54	0.00e+00	1014.00
IUUC-Eeu-034818	Erinaceus europaeus	85.96	0.00e+00	966.00
IUUC-Fca-035535	Felis catus	87.57	0.00e+00	862.00
IUUC-Fal-036627	Ficedula albicollis	82.80	0.00e+00	899.00
IUUC-Fox-037904	Fusarium oxysporum	37.33	2.00e-53	203.00
IUUC-Fso-038170	Fusarium solani	34.10	3.00e-53	203.00
IUUC-Gmo-039499	Gadus morhua	65.74	0.00e+00	669.00
IUUC-Ggr-040042	Gaeumannomyces graminis	36.53	1.00e-61	231.00
IUUC-Gga-040571	Gallus gallus	82.74	0.00e+00	905.00
IUUC-Gac-041345	Gasterosteus aculeatus	74.35	0.00e+00	662.00
IUUC-Gma-044407	Glycine max	35.13	6.00e-59	221.00
IUUC-Ggo-044652	Gorilla gorilla	90.05	0.00e+00	1032.00
IUUC-Hsa-045864	Homo sapiens	90.05	0.00e+00	1032.00
IUUC-Hvu-047071	Hordeum vulgare	33.50	5.00e-53	201.00
IUUC-Kpa-049132	Komagataella pastoris	30.49	6.00e-45	175.00
IUUC-Lch-050040	Latimeria chalumnae	75.00	0.00e+00	797.00
IUUC-Loc-052449	Lepisosteus oculatus	78.21	0.00e+00	712.00
IUUC-Lma-053248	Leptosphaeria maculans	35.47	2.00e-56	214.00
IUUC-Laf-054121	Loxodonta africana	88.87	0.00e+00	987.00
IUUC-Mcc-055514	Macaca mulatta	90.38	0.00e+00	1016.00
IUUC-Meu-056873	Macropus eugenii	74.78	2.00e-175	609.00
IUUC-Mor-057243	Magnaporthe oryzae	34.18	2.00e-58	220.00
IUUC-Mpo-057439	Magnaporthe poae	36.53	5.00e-61	229.00
IUUC-Mtr-058457	Medicago truncatula	34.36	9.00e-58	217.00
IUUC-Mla-058929	Melampsora laricipopulina	31.99	1.00e-57	218.00
IUUC-Mga-060157	Meleagris gallopavo	82.42	0.00e+00	905.00
IUUC-Mvi-060442	Microbotryum violaceum	32.19	6.00e-54	206.00
IUUC-Mmr-061062	Microcebus murinus	91.08	0.00e+00	1044.00
IUUC-Mdo-062798	Monodelphis domestica	83.90	0.00e+00	939.00
IUUC-Mmu-064050	Mus musculus	88.45	0.00e+00	1042.00
IUUC-Mac-065619	Musa acuminata	35.29	4.00e-55	208.00
IUUC-Mpu-066554	Mustela putorius furo	90.07	0.00e+00	976.00
IUUC-Mlu-068003	Myotis lucifugus	88.51	0.00e+00	988.00
IUUC-Nfi-068612	Neosartorya fischeri	35.71	2.00e-62	233.00
IUUC-Ncr-068878	Neurospora crassa	36.25	1.00e-52	201.00
IUUC-Nle-069661	Nomascus leucogenys	90.91	0.00e+00	1020.00
IUUC-Opr-070944	Ochotona princeps	78.55	1.00e-164	572.00
IUUC-Ont-071266	Oreochromis niloticus	78.04	0.00e+00	689.00
IUUC-Oan-073442	Ornithorhynchus anatinus	83.25	0.00e+00	949.00
IUUC-Ocu-073788	Oryctolagus cuniculus	86.53	0.00e+00	915.00
IUUC-Oba-075085	Oryza barthii	34.17	3.00e-38	151.00
IUUC-Obr-076663	Oryza brachyantha	33.42	2.00e-46	180.00
IUUC-Ogl-076937	Oryza glaberrima	30.81	1.00e-49	191.00
IUUC-Ogu-078909	Oryza glumaepatula	30.42	7.00e-48	184.00
IUUC-Oin-079617	Oryza indica	32.23	3.00e-49	189.00
IUUC-Olo-081043	Oryza longistaminata	26.29	2.00e-25	110.00
IUUC-Ome-081646	Oryza meridionalis	25.26	2.00e-24	107.00
IUUC-Oni-082914	Oryza nivara	30.42	5.00e-48	185.00
IUUC-Oru-084878	Oryza rufipogon	30.42	5.00e-48	185.00
IUUC-Osa-085822	Oryza sativa	31.06	8.00e-52	197.00
IUUC-Ola-086931	Oryzias latipes	75.05	0.00e+00	658.00
IUUC-Oga-088443	Otolemur garnettii	90.74	0.00e+00	1040.00
IUUC-Oar-089325	Ovis aries	88.10	0.00e+00	868.00
IUUC-Ptr-091584	Pan troglodytes	86.11	0.00e+00	943.00
IUUC-Pan-092551	Papio anubis	87.76	0.00e+00	977.00
IUUC-Psi-093366	Pelodiscus sinensis	80.35	2.00e-175	608.00
IUUC-Pno-095136	Phaeosphaeria nodorum	36.39	2.00e-52	200.00
IUUC-Ppa-095574	Physcomitrella patens	35.76	1.00e-58	220.00
IUUC-Pfo-097462	Poecilia formosa	71.46	0.00e+00	694.00
IUUC-Pab-098547	Pongo abelii	90.38	0.00e+00	1013.00
IUUC-Pop-099529	Populus trichocarpa	37.18	8.00e-62	231.00
IUUC-Pca-101066	Procavia capensis	79.11	0.00e+00	881.00
IUUC-Ppe-102110	Prunus persica	36.13	4.00e-59	221.00
IUUC-Pva-103015	Pteropus vampyrus	88.16	0.00e+00	995.00
IUUC-Ptt-103998	Puccinia triticina	32.04	5.00e-53	202.00
IUUC-Pte-104417	Pyrenophora teres	33.58	4.00e-54	206.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.60	5.00e-54	206.00
IUUC-Rno-105533	Rattus norvegicus	88.98	0.00e+00	1049.00
IUUC-Sce-106160	Saccharomyces cerevisiae	28.48	1.00e-39	158.00
IUUC-Sha-106590	Sarcophilus harrisii	84.25	0.00e+00	930.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	35.12	2.00e-56	213.00
IUUC-Spo-108353	Schizosaccharomyces pombe	36.64	8.00e-65	241.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	37.69	3.00e-58	219.00
IUUC-Smo-108842	Selaginella moellendorffii	36.92	7.00e-38	150.00
IUUC-Sit-110781	Setaria italica	33.26	1.00e-56	214.00
IUUC-Sly-111797	Solanum lycopersicum	34.78	7.00e-56	211.00
IUUC-Stu-112188	Solanum tuberosum	34.77	5.00e-55	208.00
IUUC-Sbi-114862	Sorghum bicolor	33.33	3.00e-46	179.00
IUUC-Sre-115162	Sporisorium reilianum	34.80	5.00e-66	245.00
IUUC-Ssc-115505	Sus scrofa	96.12	2.00e-166	577.00
IUUC-Tgu-116535	Taeniopygia guttata	83.09	0.00e+00	898.00
IUUC-Tru-117542	Takifugu rubripes	76.77	0.00e+00	706.00
IUUC-Tni-120200	Tetraodon nigroviridis	76.56	0.00e+00	701.00
IUUC-Tca-121548	Theobroma cacao	34.92	3.00e-44	173.00
IUUC-Tre-122124	Trichoderma reesei	33.13	9.00e-59	221.00
IUUC-Tvi-122457	Trichoderma virens	33.59	3.00e-52	199.00
IUUC-Tae-125646	Triticum aestivum	34.18	1.00e-55	211.00
IUUC-Tme-127180	Tuber melanosporum	39.89	3.00e-69	256.00
IUUC-Tbe-127530	Tupaia belangeri	76.68	0.00e+00	785.00
IUUC-Ttr-128549	Tursiops truncatus	79.46	0.00e+00	867.00
IUUC-Uma-129381	Ustilago maydis	34.70	6.00e-65	242.00
IUUC-Vda-129889	Verticillium dahliae	32.63	7.00e-52	199.00
IUUC-Vpa-130100	Vicugna pacos	81.54	0.00e+00	889.00
IUUC-Vvi-131366	Vitis vinifera	36.64	5.00e-64	238.00
IUUC-Xtr-132048	Xenopus tropicalis	77.39	0.00e+00	855.00
IUUC-Xma-133593	Xiphophorus maculatus	70.70	0.00e+00	689.00
IUUC-Yli-134338	Yarrowia lipolytica	30.17	8.00e-33	135.00
IUUC-Zma-135586	Zea mays	31.27	4.00e-50	192.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence