iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID	HINT
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	58.28	1.00e-105	382.00	IUUC-Dme-032001
E3 activity/RING/RING	96.37	0.00e+00	1691.00	IUUC-Hsa-046661

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MNSMDRHIQQ TNDRLQCIKQ HLQNPANFHN AATELLDWCG DPRAFQRPFE QSLMGCLTVV 60
SRVAAQQGFD LDLGYRLLAV CAANRDKFTP KSAALLSSWC EELGRLLLLR HQKSRQNDPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGCTCGGC TCCGGGCGAG TTGATTCACT TACTCACCCC CTAACGCCGA GTTCCTTTTC 60
ACTGTCTGTG GACATTAAAA AAGCGAGCGG CGGCGGCGGG CGCCCCGGAG AGCAAGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004181--Znf_MIZ
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51044--ZF_SP_RING

Pfam

PF02891--zf-MIZ

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0048844--P:artery morphogenesis
GO:0007569--P:cell aging
GO:0048589--P:developmental growth
GO:0003007--P:heart morphogenesis
GO:0001701--P:in utero embryonic development
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045747--P:positive regulation of Notch signaling pathway
GO:0045582--P:positive regulation of T cell differentiation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0001570--P:vasculogenesis
GO:0007296--P:vitellogenesis

KEGG

rno:361103

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001794	Ailuropoda melanoleuca	93.59	0.00e+00	1676.00
IUUC-Apl-003273	Anas platyrhynchos	86.04	0.00e+00	1384.00
IUUC-Aca-004401	Anolis carolinensis	87.27	0.00e+00	1586.00
IUUC-Aly-005490	Arabidopsis lyrata	26.97	5.00e-20	93.20
IUUC-Ame-010808	Astyanax mexicanus	80.17	0.00e+00	1273.00
IUUC-Bta-012614	Bos taurus	95.02	0.00e+00	1671.00
IUUC-Cja-018964	Callithrix jacchus	94.83	0.00e+00	1584.00
IUUC-Cfa-020641	Canis familiaris	96.27	0.00e+00	1701.00
IUUC-Cpo-022418	Cavia porcellus	96.18	0.00e+00	1675.00
IUUC-Cre-022902	Chlamydomonas reinhardtii	23.23	1.00e-04	41.20
IUUC-Csa-023718	Chlorocebus sabaeus	94.93	0.00e+00	1594.00
IUUC-Cin-025758	Ciona intestinalis	60.86	3.00e-110	393.00
IUUC-Csv-026050	Ciona savignyi	60.07	2.00e-104	373.00
IUUC-Dre-028668	Danio rerio	80.25	0.00e+00	1258.00
IUUC-Dno-029204	Dasypus novemcinctus	96.99	0.00e+00	842.00
IUUC-Dor-030159	Dipodomys ordii	95.08	0.00e+00	987.00
IUUC-Dme-032001	Drosophila melanogaster	59.26	4.00e-106	379.00
IUUC-Ete-032521	Echinops telfairi	92.22	0.00e+00	1601.00
IUUC-Eca-034269	Equus caballus	95.50	0.00e+00	1677.00
IUUC-Eeu-034484	Erinaceus europaeus	94.53	0.00e+00	1172.00
IUUC-Fca-036463	Felis catus	95.50	0.00e+00	758.00
IUUC-Fal-036827	Ficedula albicollis	86.72	0.00e+00	1381.00
IUUC-Gmo-039165	Gadus morhua	76.03	0.00e+00	692.00
IUUC-Gga-040680	Gallus gallus	87.31	0.00e+00	1491.00
IUUC-Gac-041570	Gasterosteus aculeatus	79.44	0.00e+00	1370.00
IUUC-Ggo-045289	Gorilla gorilla	94.84	0.00e+00	1630.00
IUUC-Hsa-046661	Homo sapiens	94.93	0.00e+00	1632.00
IUUC-Itr-049077	Ictidomys tridecemlineatus	95.37	0.00e+00	920.00
IUUC-Lch-050080	Latimeria chalumnae	83.65	0.00e+00	1347.00
IUUC-Lpe-050926	Leersia perrieri	44.34	4.00e-20	93.60
IUUC-Loc-052797	Lepisosteus oculatus	84.69	0.00e+00	1355.00
IUUC-Laf-054407	Loxodonta africana	90.89	0.00e+00	1467.00
IUUC-Mcc-055011	Macaca mulatta	95.60	0.00e+00	1615.00
IUUC-Meu-056748	Macropus eugenii	86.13	0.00e+00	1377.00
IUUC-Mga-059480	Meleagris gallopavo	88.07	0.00e+00	1334.00
IUUC-Mmr-061745	Microcebus murinus	95.70	0.00e+00	1692.00
IUUC-Mdo-062087	Monodelphis domestica	94.85	0.00e+00	1340.00
IUUC-Mmu-063802	Mus musculus	99.23	0.00e+00	1675.00
IUUC-Mpu-065779	Mustela putorius furo	85.08	0.00e+00	1283.00
IUUC-Mlu-067227	Myotis lucifugus	87.98	0.00e+00	1442.00
IUUC-Nle-069784	Nomascus leucogenys	95.32	0.00e+00	1650.00
IUUC-Opr-070817	Ochotona princeps	94.46	0.00e+00	979.00
IUUC-Ont-072059	Oreochromis niloticus	76.65	0.00e+00	1264.00
IUUC-Oan-073685	Ornithorhynchus anatinus	89.58	0.00e+00	744.00
IUUC-Ocu-073807	Oryctolagus cuniculus	95.03	0.00e+00	1658.00
IUUC-Opu-083841	Oryza punctata	44.34	2.00e-20	94.70
IUUC-Ola-087350	Oryzias latipes	73.85	0.00e+00	976.00
IUUC-Oga-088062	Otolemur garnettii	93.52	0.00e+00	1447.00
IUUC-Oar-089253	Ovis aries	89.76	0.00e+00	1388.00
IUUC-Ptr-090863	Pan troglodytes	94.84	0.00e+00	1632.00
IUUC-Pan-092229	Papio anubis	95.51	0.00e+00	1612.00
IUUC-Psi-094030	Pelodiscus sinensis	85.75	0.00e+00	1496.00
IUUC-Pfo-096851	Poecilia formosa	80.04	0.00e+00	1317.00
IUUC-Pab-097748	Pongo abelii	95.70	0.00e+00	1531.00
IUUC-Ppe-101666	Prunus persica	25.56	1.00e-18	89.00
IUUC-Pva-103063	Pteropus vampyrus	93.01	0.00e+00	1612.00
IUUC-Sha-107172	Sarcophilus harrisii	89.39	0.00e+00	1484.00
IUUC-Ssl-108401	Sclerotinia sclerotiorum	22.07	1.00e-15	79.30
IUUC-Smo-109072	Selaginella moellendorffii	33.33	3.00e-13	71.60
IUUC-Sly-111180	Solanum lycopersicum	37.14	3.00e-21	97.40
IUUC-Ssc-116368	Sus scrofa	96.36	0.00e+00	1684.00
IUUC-Tgu-117017	Taeniopygia guttata	85.85	0.00e+00	1314.00
IUUC-Tru-118190	Takifugu rubripes	78.05	0.00e+00	1054.00
IUUC-Tsy-119246	Tarsius syrichta	69.81	5.00e-74	273.00
IUUC-Tni-120276	Tetraodon nigroviridis	73.21	0.00e+00	1054.00
IUUC-Tbe-127370	Tupaia belangeri	83.83	0.00e+00	874.00
IUUC-Ttr-128851	Tursiops truncatus	92.62	0.00e+00	1618.00
IUUC-Uma-129549	Ustilago maydis	31.08	7.00e-27	115.00
IUUC-Xtr-132102	Xenopus tropicalis	79.05	0.00e+00	1347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence