iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090083

Ensembl Protein ID

ENSOARP00000022009.1

UniProt Accession

W5QH10; W5QH10_SHEEP

Genbank Protein ID

ENSOARP00000022009

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01009143

Gene Name

BCL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020487.1	ENSOART00000022314.1	ENSOARP00000022009.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	3.60e-14	53.1	33	99

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.dvqpevfrallkFlYtgklden 68
           +Dv++vv +e+f+ahk vL+a+S  Fy+ f+ +l+ +   + ++++ ++ pe f  ll+F+Yt++l++ 
   Q: 33   TDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCN--LSVINLDpEINPEGFCILLDFMYTSRLNLR 99
           7**********************************76..699999988*****************9875 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

KMASPADSCI QFTRHASDVL LNLNRLRSRD ILTDVVIVVS REQFRAHKTV LMACSGLFYS 60
IFTDQLKCNL SVINLDPEIN PEGFCILLDF MYTSRLNLRE GNIMAVMATA MYLQMEHVVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTAAGCA AAATTTTAGA CTGTGAATCA AGGCACTGGG TAAGTAAATT GAATTATACG 60
ATTTACAGTT TTGTGGACAA ACTGTTTCTT TTGAATTGCC AGTGAATGTG TCTGTGAACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005657--C:replication fork
GO:0031490--F:chromatin DNA binding
GO:0001161--F:intronic transcription regulatory region sequence-specific DNA binding
GO:0046872--F:metal ion binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227--F:transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0030036--P:actin cytoskeleton organization
GO:0030183--P:B cell differentiation
GO:0000902--P:cell morphogenesis
GO:0006974--P:cellular response to DNA damage stimulus
GO:0048821--P:erythrocyte development
GO:0002467--P:germinal center formation
GO:0043066--P:negative regulation of apoptotic process
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0001953--P:negative regulation of cell-matrix adhesion
GO:2000773--P:negative regulation of cellular senescence
GO:0048294--P:negative regulation of isotype switching to IgE isotypes
GO:0032764--P:negative regulation of mast cell cytokine production
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0030890--P:positive regulation of B cell proliferation
GO:0051272--P:positive regulation of cellular component movement
GO:0031065--P:positive regulation of histone deacetylation
GO:0045666--P:positive regulation of neuron differentiation
GO:0000060--P:protein import into nucleus, translocation
GO:0043087--P:regulation of GTPase activity
GO:0050727--P:regulation of inflammatory response
GO:0043380--P:regulation of memory T cell differentiation
GO:0007266--P:Rho protein signal transduction
GO:0007283--P:spermatogenesis
GO:0042092--P:type 2 immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001625	Ailuropoda melanoleuca	84.36	0.00e+00	1201.00
IUUC-Atr-002779	Amborella trichopoda	34.44	9.00e-06	45.10
IUUC-Apl-003263	Anas platyrhynchos	67.03	0.00e+00	961.00
IUUC-Ame-010714	Astyanax mexicanus	49.00	0.00e+00	637.00
IUUC-Bta-012576	Bos taurus	87.65	0.00e+00	1214.00
IUUC-Cja-018906	Callithrix jacchus	83.13	0.00e+00	1203.00
IUUC-Cfa-021058	Canis familiaris	82.78	0.00e+00	1175.00
IUUC-Cpo-022328	Cavia porcellus	82.58	0.00e+00	1198.00
IUUC-Csa-023942	Chlorocebus sabaeus	83.40	0.00e+00	1206.00
IUUC-Cho-024599	Choloepus hoffmanni	76.81	0.00e+00	652.00
IUUC-Dre-027605	Danio rerio	50.07	0.00e+00	655.00
IUUC-Dno-029476	Dasypus novemcinctus	77.87	0.00e+00	1130.00
IUUC-Dor-030724	Dipodomys ordii	82.30	0.00e+00	1159.00
IUUC-Ete-032678	Echinops telfairi	80.66	0.00e+00	1127.00
IUUC-Eca-034377	Equus caballus	84.79	0.00e+00	1208.00
IUUC-Eeu-034532	Erinaceus europaeus	92.49	0.00e+00	858.00
IUUC-Fca-036465	Felis catus	84.77	0.00e+00	1208.00
IUUC-Fal-036977	Ficedula albicollis	67.57	0.00e+00	980.00
IUUC-Gmo-039515	Gadus morhua	65.98	1.00e-85	310.00
IUUC-Gga-040505	Gallus gallus	67.30	0.00e+00	966.00
IUUC-Gac-041393	Gasterosteus aculeatus	49.66	0.00e+00	638.00
IUUC-Gma-043945	Glycine max	32.58	6.00e-05	42.70
IUUC-Ggo-044500	Gorilla gorilla	83.40	0.00e+00	1210.00
IUUC-Hsa-046648	Homo sapiens	83.26	0.00e+00	1206.00
IUUC-Itr-048732	Ictidomys tridecemlineatus	89.72	0.00e+00	1277.00
IUUC-Lch-050387	Latimeria chalumnae	54.73	0.00e+00	699.00
IUUC-Loc-052103	Lepisosteus oculatus	57.60	0.00e+00	773.00
IUUC-Laf-053636	Loxodonta africana	83.81	0.00e+00	1212.00
IUUC-Mcc-055290	Macaca mulatta	83.13	0.00e+00	1205.00
IUUC-Meu-055910	Macropus eugenii	68.63	0.00e+00	997.00
IUUC-Mga-059925	Meleagris gallopavo	66.89	0.00e+00	953.00
IUUC-Mmr-060855	Microcebus murinus	83.54	0.00e+00	1189.00
IUUC-Mmu-063292	Mus musculus	81.78	0.00e+00	1147.00
IUUC-Mpu-066598	Mustela putorius furo	84.50	0.00e+00	1179.00
IUUC-Mlu-067370	Myotis lucifugus	83.04	0.00e+00	1161.00
IUUC-Nle-069870	Nomascus leucogenys	83.13	0.00e+00	1204.00
IUUC-Opr-070986	Ochotona princeps	80.25	0.00e+00	1121.00
IUUC-Ont-072475	Oreochromis niloticus	49.93	1.00e-175	610.00
IUUC-Oan-073596	Ornithorhynchus anatinus	72.93	0.00e+00	1020.00
IUUC-Ocu-073970	Oryctolagus cuniculus	82.49	0.00e+00	1204.00
IUUC-Ola-087102	Oryzias latipes	49.59	0.00e+00	643.00
IUUC-Oga-088873	Otolemur garnettii	83.13	0.00e+00	1203.00
IUUC-Ptr-090628	Pan troglodytes	83.40	0.00e+00	1209.00
IUUC-Pan-092324	Papio anubis	83.13	0.00e+00	1199.00
IUUC-Psi-093695	Pelodiscus sinensis	68.26	0.00e+00	941.00
IUUC-Pfo-096460	Poecilia formosa	48.51	0.00e+00	628.00
IUUC-Pab-098012	Pongo abelii	83.26	0.00e+00	1209.00
IUUC-Pca-100127	Procavia capensis	88.62	0.00e+00	1166.00
IUUC-Pva-102830	Pteropus vampyrus	82.99	0.00e+00	1175.00
IUUC-Rno-105752	Rattus norvegicus	82.05	0.00e+00	1148.00
IUUC-Sha-107259	Sarcophilus harrisii	72.52	0.00e+00	1040.00
IUUC-Sly-111885	Solanum lycopersicum	33.71	1.00e-04	41.60
IUUC-Stu-112863	Solanum tuberosum	33.71	1.00e-04	41.20
IUUC-Sar-113610	Sorex araneus	92.63	0.00e+00	1066.00
IUUC-Ssc-115327	Sus scrofa	85.60	0.00e+00	1217.00
IUUC-Tgu-116457	Taeniopygia guttata	67.85	0.00e+00	990.00
IUUC-Tru-118520	Takifugu rubripes	49.66	0.00e+00	646.00
IUUC-Tni-119969	Tetraodon nigroviridis	54.83	0.00e+00	702.00
IUUC-Tbe-127327	Tupaia belangeri	83.13	0.00e+00	1193.00
IUUC-Ttr-129204	Tursiops truncatus	83.68	0.00e+00	1161.00
IUUC-Xtr-132937	Xenopus tropicalis	56.24	0.00e+00	730.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence