iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068842

Ensembl Protein ID

EAA28414

UniProt Accession

Q7RZI0; HIR1_NEUCR

Genbank Protein ID

CAE85596.1; EAA28414.2

Protein Name

Protein hir-1

Genbank Nucleotide ID

BX897678; CM002241

Gene Name

hir-1; B10H18.120; NCU04035

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU04035	EAA28414	EAA28414

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-26	89.7	129	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v +la+ +d  llvs + D +i vW+ +t+ +lk
   Q: 129  GHDNDVQDLAWsPDnSLLVSVGLDSKIVVWSGHTFEKLK 167
           89**********88899**************99988776 PP

Organism

Neurospora crassa

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MHLIKPSWLS HSGEQKDFEV YSCHVSPDGK RLATAGGDGH VRVWSVEAIF NSHDRNYTKP 60
RQLCHMSHHL GTIHSVRFSP NGRYLASGAD DKIICIYHLD SNPPSHTSTF GTNEPPPVEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGACGGGC GGAACGAAGA GCAGCCCCAG GCGGCCGGGG CAACAACTAC CTAACTGCCT 60
GACGCGGCGC GGGCAATCCA TCGTCCCCGT TGCCCGTCGC GCATCCCAAT CAGAATCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000417--C:HIR complex
GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

KEGG

ncr:NCU04035

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	33.18	7.00e-66	244.00
IUUC-Aml-001723	Ailuropoda melanoleuca	31.42	8.00e-60	223.00
IUUC-Atr-003132	Amborella trichopoda	31.21	1.00e-68	253.00
IUUC-Apl-003197	Anas platyrhynchos	32.00	1.00e-60	226.00
IUUC-Aca-004733	Anolis carolinensis	30.39	9.00e-66	243.00
IUUC-Aly-005446	Arabidopsis lyrata	32.50	6.00e-67	247.00
IUUC-Ath-007627	Arabidopsis thaliana	31.91	5.00e-70	257.00
IUUC-Ago-007766	Ashbya gossypii	33.72	3.00e-123	434.00
IUUC-Acl-008104	Aspergillus clavatus	56.21	0.00e+00	1178.00
IUUC-Afl-008591	Aspergillus flavus	56.42	0.00e+00	1170.00
IUUC-Afu-008781	Aspergillus fumigatus	56.51	0.00e+00	1116.00
IUUC-Ani-009272	Aspergillus nidulans	53.33	0.00e+00	1054.00
IUUC-Ang-009655	Aspergillus niger	56.46	0.00e+00	1172.00
IUUC-Aor-010119	Aspergillus oryzae	56.42	0.00e+00	1171.00
IUUC-Ate-010530	Aspergillus terreus	53.67	0.00e+00	1073.00
IUUC-Bgr-012237	Blumeria graminis	63.06	0.00e+00	1258.00
IUUC-Bta-013320	Bos taurus	29.76	4.00e-61	228.00
IUUC-Bci-013795	Botrytis cinerea	65.26	0.00e+00	1352.00
IUUC-Bdi-014075	Brachypodium distachyon	33.08	1.00e-71	263.00
IUUC-Bol-016440	Brassica oleracea	32.35	1.00e-67	249.00
IUUC-Bra-016651	Brassica rapa	35.80	8.00e-68	250.00
IUUC-Cel-018692	Caenorhabditis elegans	25.37	4.00e-32	132.00
IUUC-Cja-018987	Callithrix jacchus	29.36	7.00e-55	207.00
IUUC-Cfa-020132	Canis familiaris	31.42	8.00e-60	223.00
IUUC-Cpo-021484	Cavia porcellus	31.67	6.00e-64	237.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	29.55	3.00e-53	202.00
IUUC-Csa-023081	Chlorocebus sabaeus	29.82	2.00e-64	238.00
IUUC-Cin-025182	Ciona intestinalis	33.57	1.00e-61	230.00
IUUC-Csv-026154	Ciona savignyi	32.21	2.00e-58	219.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	71.25	0.00e+00	1514.00
IUUC-Cne-026891	Cryptococcus neoformans	41.31	1.00e-86	312.00
IUUC-Cme-027349	Cyanidioschyzon merolae	27.00	4.00e-32	132.00
IUUC-Dre-027655	Danio rerio	29.61	3.00e-63	235.00
IUUC-Dno-029557	Dasypus novemcinctus	28.48	9.00e-50	190.00
IUUC-Dor-030687	Dipodomys ordii	29.10	1.00e-51	196.00
IUUC-Dse-031334	Dothistroma septosporum	55.33	0.00e+00	1110.00
IUUC-Dme-031746	Drosophila melanogaster	31.64	2.00e-63	236.00
IUUC-Ete-032384	Echinops telfairi	25.81	6.00e-44	171.00
IUUC-Eca-033430	Equus caballus	29.07	6.00e-60	224.00
IUUC-Fca-036121	Felis catus	31.40	1.00e-60	226.00
IUUC-Fal-036817	Ficedula albicollis	32.00	1.00e-60	226.00
IUUC-Fox-037906	Fusarium oxysporum	78.31	0.00e+00	993.00
IUUC-Fso-038409	Fusarium solani	73.83	0.00e+00	1557.00
IUUC-Gmo-039151	Gadus morhua	32.55	2.00e-64	238.00
IUUC-Ggr-040016	Gaeumannomyces graminis	73.10	0.00e+00	1543.00
IUUC-Gga-040936	Gallus gallus	32.22	1.00e-64	240.00
IUUC-Gac-041405	Gasterosteus aculeatus	31.89	2.00e-61	229.00
IUUC-Gma-044252	Glycine max	33.01	6.00e-71	261.00
IUUC-Ggo-045430	Gorilla gorilla	29.82	2.00e-64	239.00
IUUC-Hsa-046442	Homo sapiens	29.82	2.00e-64	239.00
IUUC-Hvu-047587	Hordeum vulgare	34.97	7.00e-59	220.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	33.33	2.00e-47	180.00
IUUC-Kpa-049145	Komagataella pastoris	44.42	6.00e-116	410.00
IUUC-Lch-050474	Latimeria chalumnae	31.98	1.00e-63	236.00
IUUC-Lpe-051209	Leersia perrieri	34.15	1.00e-63	236.00
IUUC-Loc-052119	Lepisosteus oculatus	31.38	2.00e-64	238.00
IUUC-Lma-053237	Leptosphaeria maculans	55.13	0.00e+00	1129.00
IUUC-Laf-053718	Loxodonta africana	29.75	2.00e-64	239.00
IUUC-Mcc-055621	Macaca mulatta	29.52	7.00e-55	207.00
IUUC-Meu-055914	Macropus eugenii	33.10	3.00e-44	172.00
IUUC-Mor-057090	Magnaporthe oryzae	71.00	0.00e+00	1534.00
IUUC-Mpo-057364	Magnaporthe poae	72.80	0.00e+00	1526.00
IUUC-Mtr-058691	Medicago truncatula	35.78	2.00e-69	256.00
IUUC-Mla-058914	Melampsora laricipopulina	33.79	2.00e-77	281.00
IUUC-Mga-060181	Meleagris gallopavo	32.00	1.00e-60	226.00
IUUC-Mvi-060432	Microbotryum violaceum	34.16	1.00e-64	239.00
IUUC-Mmr-060871	Microcebus murinus	31.67	7.00e-64	237.00
IUUC-Mdo-062301	Monodelphis domestica	30.39	1.00e-64	239.00
IUUC-Mmu-063888	Mus musculus	29.49	1.00e-63	236.00
IUUC-Mac-065137	Musa acuminata	36.20	3.00e-69	254.00
IUUC-Mpu-066732	Mustela putorius furo	31.42	1.00e-59	223.00
IUUC-Mlu-067542	Myotis lucifugus	28.68	7.00e-60	224.00
IUUC-Nfi-068396	Neosartorya fischeri	55.97	0.00e+00	1118.00
IUUC-Nle-070156	Nomascus leucogenys	30.20	2.00e-64	239.00
IUUC-Opr-070808	Ochotona princeps	31.45	2.00e-39	155.00
IUUC-Ont-072105	Oreochromis niloticus	29.61	3.00e-64	238.00
IUUC-Ocu-074962	Oryctolagus cuniculus	29.12	3.00e-60	224.00
IUUC-Oba-075178	Oryza barthii	35.14	1.00e-70	259.00
IUUC-Obr-076399	Oryza brachyantha	35.87	1.00e-71	262.00
IUUC-Ogu-078797	Oryza glumaepatula	35.14	1.00e-70	259.00
IUUC-Oin-080085	Oryza indica	34.15	2.00e-58	219.00
IUUC-Olo-081048	Oryza longistaminata	34.16	5.00e-49	188.00
IUUC-Ome-081324	Oryza meridionalis	35.14	1.00e-70	259.00
IUUC-Oni-082548	Oryza nivara	35.14	1.00e-70	259.00
IUUC-Opu-084008	Oryza punctata	36.12	2.00e-72	265.00
IUUC-Oru-084339	Oryza rufipogon	35.38	7.00e-71	260.00
IUUC-Osa-085782	Oryza sativa	35.38	7.00e-71	260.00
IUUC-Ola-087302	Oryzias latipes	29.24	2.00e-54	206.00
IUUC-Olu-087611	Ostreococcus lucimarinus	37.57	5.00e-75	274.00
IUUC-Oga-087935	Otolemur garnettii	29.38	4.00e-60	224.00
IUUC-Oar-089229	Ovis aries	28.08	1.00e-48	186.00
IUUC-Ptr-090715	Pan troglodytes	29.82	2.00e-64	239.00
IUUC-Pan-092318	Papio anubis	29.55	2.00e-60	225.00
IUUC-Psi-094053	Pelodiscus sinensis	31.55	5.00e-59	221.00
IUUC-Pno-094985	Phaeosphaeria nodorum	51.69	0.00e+00	1018.00
IUUC-Ppa-095819	Physcomitrella patens	34.44	2.00e-70	258.00
IUUC-Pfo-096857	Poecilia formosa	31.35	4.00e-60	224.00
IUUC-Pab-098047	Pongo abelii	29.82	2.00e-64	239.00
IUUC-Pop-099587	Populus trichocarpa	35.63	6.00e-70	257.00
IUUC-Pca-100558	Procavia capensis	34.58	2.00e-34	139.00
IUUC-Ppe-101261	Prunus persica	36.05	4.00e-72	264.00
IUUC-Pva-102683	Pteropus vampyrus	29.22	1.00e-61	229.00
IUUC-Pgr-103660	Puccinia graminis	38.65	7.00e-74	270.00
IUUC-Ptt-103900	Puccinia triticina	39.84	7.00e-74	270.00
IUUC-Pte-104209	Pyrenophora teres	53.55	0.00e+00	1132.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	53.72	0.00e+00	1127.00
IUUC-Rno-105566	Rattus norvegicus	29.63	6.00e-64	237.00
IUUC-Sce-106291	Saccharomyces cerevisiae	35.72	4.00e-125	440.00
IUUC-Sha-107514	Sarcophilus harrisii	28.77	5.00e-50	191.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	38.74	3.00e-178	617.00
IUUC-Spo-108162	Schizosaccharomyces pombe	43.10	2.00e-122	431.00
IUUC-Ssl-108629	Sclerotinia sclerotiorum	57.94	0.00e+00	809.00
IUUC-Smo-109186	Selaginella moellendorffii	32.68	3.00e-67	248.00
IUUC-Sit-110730	Setaria italica	36.36	7.00e-72	263.00
IUUC-Sly-111547	Solanum lycopersicum	33.66	1.00e-67	249.00
IUUC-Stu-112705	Solanum tuberosum	33.66	5.00e-68	251.00
IUUC-Sar-113222	Sorex araneus	28.11	7.00e-53	200.00
IUUC-Sbi-114272	Sorghum bicolor	33.59	3.00e-72	265.00
IUUC-Sre-115061	Sporisorium reilianum	33.98	2.00e-81	295.00
IUUC-Ssc-116364	Sus scrofa	29.47	5.00e-61	227.00
IUUC-Tgu-116645	Taeniopygia guttata	32.00	9.00e-61	226.00
IUUC-Tru-117590	Takifugu rubripes	29.69	3.00e-64	238.00
IUUC-Tsy-119212	Tarsius syrichta	31.95	7.00e-52	197.00
IUUC-Tni-119915	Tetraodon nigroviridis	30.21	8.00e-64	237.00
IUUC-Tca-121765	Theobroma cacao	27.12	1.00e-86	312.00
IUUC-Tre-121887	Trichoderma reesei	70.34	0.00e+00	1486.00
IUUC-Tvi-122262	Trichoderma virens	70.79	0.00e+00	1479.00
IUUC-Tae-124502	Triticum aestivum	28.20	1.00e-35	142.00
IUUC-Tur-126483	Triticum urartu	35.87	8.00e-71	260.00
IUUC-Tme-127202	Tuber melanosporum	46.30	0.00e+00	852.00
IUUC-Tbe-127350	Tupaia belangeri	26.42	1.00e-32	133.00
IUUC-Ttr-129077	Tursiops truncatus	28.51	2.00e-56	212.00
IUUC-Uma-129465	Ustilago maydis	33.07	5.00e-79	287.00
IUUC-Vda-129844	Verticillium dahliae	68.18	0.00e+00	1383.00
IUUC-Vvi-131397	Vitis vinifera	29.19	8.00e-87	313.00
IUUC-Xtr-132057	Xenopus tropicalis	30.06	6.00e-64	237.00
IUUC-Xma-134139	Xiphophorus maculatus	30.59	4.00e-51	194.00
IUUC-Yli-134424	Yarrowia lipolytica	39.07	0.00e+00	674.00
IUUC-Zma-135506	Zea mays	36.41	3.00e-72	265.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence