iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066604

Ensembl Protein ID

ENSMPUP00000009034.1

UniProt Accession

M3YCH7; M3YCH7_MUSPF

Genbank Protein ID

ENSMPUP00000009034

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01016666

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000009110.1	ENSMPUT00000009185.1	ENSMPUP00000009034.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-55	187.1	9	142
UBD/UBC-like/UBD_UBC	7.60e-84	278.8	10	145

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeee 90
           l +el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  +
   Q: 9    LSHELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--S 94
           678********************.9************************************************************9..* PP
   S: 91   kWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +Wspal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 95   QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 142
           ********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 3    kkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsa 91
            +el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+
   Q: 10   SHELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSP 98
           68*************************************************************************************** PP
   S: 92   altlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           alt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 99   ALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 145
           **********************************************8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MKSQTLNQLS HELNDLARDP PAQCSAGPVG DDMFHWQATI MGPNDSPYQG GVFFLTIHFP 60
TDYPFKPPKV AFTTRIYHPN INSNGSICLD ILRSQWSPAL TISKVLLSIC SLLCDPNPDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGAAAGGG TGAATATGTG GGCCTGTGAG AGTGGGGGAA GGAAGGGACA GAGGGAGAGG 60
GAGAAAGAGA ATCTGAAGCA CGTTCCACAC CCTGGGGAGC CAGATGCTGG GCTCGATCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	100.00	2.00e-81	293.00
IUUC-Atr-002861	Amborella trichopoda	78.47	1.00e-67	248.00
IUUC-Apl-003199	Anas platyrhynchos	100.00	2.00e-81	293.00
IUUC-Aca-005236	Anolis carolinensis	95.89	2.00e-82	296.00
IUUC-Acl-008266	Aspergillus clavatus	82.07	4.00e-71	259.00
IUUC-Afl-008709	Aspergillus flavus	79.58	1.00e-68	253.00
IUUC-Afu-008956	Aspergillus fumigatus	82.76	2.00e-71	260.00
IUUC-Ang-009725	Aspergillus niger	84.80	3.00e-62	230.00
IUUC-Aor-010157	Aspergillus oryzae	80.82	7.00e-71	258.00
IUUC-Ate-010438	Aspergillus terreus	81.38	2.00e-70	256.00
IUUC-Ame-011831	Astyanax mexicanus	93.79	3.00e-80	290.00
IUUC-Bgr-012238	Blumeria graminis	77.24	8.00e-67	245.00
IUUC-Bta-013158	Bos taurus	95.89	2.00e-82	296.00
IUUC-Bci-013661	Botrytis cinerea	80.69	4.00e-71	259.00
IUUC-Bol-015722	Brassica oleracea	78.00	2.00e-68	251.00
IUUC-Cja-019886	Callithrix jacchus	95.89	2.00e-82	296.00
IUUC-Cfa-020436	Canis familiaris	95.89	2.00e-82	296.00
IUUC-Cpo-021714	Cavia porcellus	93.84	2.00e-80	290.00
IUUC-Csa-023148	Chlorocebus sabaeus	91.84	8.00e-78	281.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	81.38	8.00e-71	258.00
IUUC-Dre-027758	Danio rerio	94.52	3.00e-81	293.00
IUUC-Dno-028952	Dasypus novemcinctus	100.00	1.00e-81	294.00
IUUC-Dor-030285	Dipodomys ordii	97.84	5.00e-80	289.00
IUUC-Dse-031397	Dothistroma septosporum	81.38	4.00e-71	259.00
IUUC-Dme-031594	Drosophila melanogaster	91.10	1.00e-78	284.00
IUUC-Ete-032295	Echinops telfairi	100.00	2.00e-81	293.00
IUUC-Eca-033293	Equus caballus	100.00	1.00e-82	297.00
IUUC-Eeu-034766	Erinaceus europaeus	96.43	2.00e-78	283.00
IUUC-Fca-035917	Felis catus	93.84	4.00e-81	293.00
IUUC-Fal-036904	Ficedula albicollis	97.84	5.00e-80	289.00
IUUC-Fox-038021	Fusarium oxysporum	81.38	1.00e-70	258.00
IUUC-Fso-038297	Fusarium solani	80.69	2.00e-70	257.00
IUUC-Gmo-038898	Gadus morhua	93.66	2.00e-78	283.00
IUUC-Ggr-039912	Gaeumannomyces graminis	76.67	2.00e-66	244.00
IUUC-Gga-040758	Gallus gallus	95.89	2.00e-82	296.00
IUUC-Gac-042231	Gasterosteus aculeatus	93.15	5.00e-80	289.00
IUUC-Ggo-045375	Gorilla gorilla	99.29	1.00e-81	294.00
IUUC-Hsa-045885	Homo sapiens	95.89	2.00e-82	296.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	99.29	5.00e-82	295.00
IUUC-Lpe-051317	Leersia perrieri	77.18	5.00e-68	249.00
IUUC-Loc-052788	Lepisosteus oculatus	97.86	1.00e-80	291.00
IUUC-Lma-053121	Leptosphaeria maculans	81.38	3.00e-71	260.00
IUUC-Laf-053580	Loxodonta africana	100.00	2.00e-81	293.00
IUUC-Mcc-054673	Macaca mulatta	99.29	9.00e-82	295.00
IUUC-Meu-056462	Macropus eugenii	96.40	7.00e-79	285.00
IUUC-Mor-057235	Magnaporthe oryzae	80.69	4.00e-70	256.00
IUUC-Mpo-057596	Magnaporthe poae	76.67	4.00e-66	243.00
IUUC-Mla-059189	Melampsora laricipopulina	77.40	1.00e-65	241.00
IUUC-Mga-059237	Meleagris gallopavo	96.48	3.00e-80	290.00
IUUC-Mmr-061474	Microcebus murinus	100.00	2.00e-81	294.00
IUUC-Mdo-062962	Monodelphis domestica	95.89	2.00e-82	296.00
IUUC-Mmu-063518	Mus musculus	95.89	2.00e-82	296.00
IUUC-Nfi-068599	Neosartorya fischeri	82.76	2.00e-71	260.00
IUUC-Nle-069800	Nomascus leucogenys	96.55	1.00e-78	285.00
IUUC-Opr-070191	Ochotona princeps	97.84	5.00e-80	289.00
IUUC-Ont-071766	Oreochromis niloticus	94.52	2.00e-81	293.00
IUUC-Oan-073026	Ornithorhynchus anatinus	92.91	7.00e-78	282.00
IUUC-Ocu-074315	Oryctolagus cuniculus	95.89	2.00e-82	296.00
IUUC-Obr-076691	Oryza brachyantha	77.85	4.00e-68	250.00
IUUC-Ome-081987	Oryza meridionalis	77.08	4.00e-67	246.00
IUUC-Opu-083833	Oryza punctata	77.78	1.00e-67	248.00
IUUC-Ola-086331	Oryzias latipes	94.52	2.00e-81	293.00
IUUC-Oga-088477	Otolemur garnettii	93.15	3.00e-81	293.00
IUUC-Oar-090038	Ovis aries	93.84	4.00e-81	293.00
IUUC-Ptr-090707	Pan troglodytes	95.89	2.00e-82	296.00
IUUC-Pan-092143	Papio anubis	95.89	2.00e-82	296.00
IUUC-Psi-094076	Pelodiscus sinensis	93.84	4.00e-81	293.00
IUUC-Pma-094405	Petromyzon marinus	94.81	5.00e-75	272.00
IUUC-Pno-094765	Phaeosphaeria nodorum	81.38	3.00e-71	260.00
IUUC-Pfo-096753	Poecilia formosa	94.52	2.00e-81	293.00
IUUC-Pab-097764	Pongo abelii	95.89	2.00e-82	296.00
IUUC-Ppe-101431	Prunus persica	78.00	2.00e-68	250.00
IUUC-Pgr-103381	Puccinia graminis	79.31	1.00e-66	246.00
IUUC-Ptt-103723	Puccinia triticina	77.86	1.00e-61	228.00
IUUC-Pte-104015	Pyrenophora teres	81.38	3.00e-71	259.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	81.38	3.00e-71	259.00
IUUC-Rno-105498	Rattus norvegicus	93.84	4.00e-81	293.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	80.95	2.00e-70	257.00
IUUC-Spo-108032	Schizosaccharomyces pombe	80.95	1.00e-70	258.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	81.38	2.00e-71	260.00
IUUC-Sar-113302	Sorex araneus	100.00	2.00e-81	293.00
IUUC-Ssc-116154	Sus scrofa	95.10	2.00e-80	290.00
IUUC-Tgu-116727	Taeniopygia guttata	93.84	4.00e-81	293.00
IUUC-Tru-118272	Takifugu rubripes	94.52	6.00e-81	292.00
IUUC-Tsy-119491	Tarsius syrichta	97.12	9.00e-77	279.00
IUUC-Tni-120056	Tetraodon nigroviridis	94.52	6.00e-81	292.00
IUUC-Tre-122125	Trichoderma reesei	78.77	1.00e-68	251.00
IUUC-Tvi-122296	Trichoderma virens	78.77	1.00e-68	251.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	9.00e-68	247.00
IUUC-Uma-129648	Ustilago maydis	79.72	1.00e-68	251.00
IUUC-Vda-129695	Verticillium dahliae	81.38	8.00e-71	258.00
IUUC-Vpa-130446	Vicugna pacos	99.28	5.00e-80	290.00
IUUC-Vvi-131368	Vitis vinifera	78.47	3.00e-68	249.00
IUUC-Xtr-132329	Xenopus tropicalis	95.89	2.00e-82	296.00
IUUC-Xma-133829	Xiphophorus maculatus	94.52	2.00e-81	293.00
IUUC-Zma-135956	Zea mays	77.08	4.00e-67	246.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence