iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028096

Ensembl Protein ID

ENSDARP00000113067.1

UniProt Accession

E9QH84; E9QH84_DANRE

Genbank Protein ID

ENSDARP00000113067

Protein Name

Gem (nuclear organelle)-associated protein 5

Genbank Nucleotide ID

CR352267

Gene Name

gemin5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000079257.4	ENSDART00000137309.1	ENSDARP00000113067.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-49	164.9	620	653
UBD/Beta-Prp	5.90e-62	210.4	31	249

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHt+++t+la+   +d++lv+ ++Dgt +vWD+ 
   Q: 620  GHTNKITDLAWsphHDGHLVTVCYDGTAQVWDVL 653
           8***********8766****************85 PP

UBD/Beta-Prp

   S: 31   dgtikvwdvttgkl..lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGs 113
            +t+ + +vt  +     +l gh++ v+   f p++    i  ++s+D+ +k+wd ++   +   + h+++++++++sp ++  lv+G+
   Q: 31   KNTVYLLNVTAASPavTGELAGHTERVSGFAFCPNEGqehICCSTSDDKKVKIWDAEQKILLKEHNVHQNTITAVHWSPvQKLLLVTGD 119
           5556566655433333899*************99988899***************************************888999**** PP
   S: 114  hdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvyslsfdsng........ 192
           +  ++ ++  +++   +  + ++ +++ c++ +p + nl++ G +D+++ + d+ k g+++++l+g h+d ++ l++ +          
   Q: 120  EKGIVVCYWFSSNDTQS--FFPEPRTIFCLSCSPHDeNLIAVGYKDGMIAVIDIsKKGEVVHRLRG-HDDEIHALAWCPRPreeplygr 205
           *******8788887776..888888899999999999*****************999********9.*********6555555666666 PP
   S: 193  ..................kelvsgsldgtvklwdlqtgecvrtl 218
                              +l+sgs+d+t ++w+  + + v+tl
   Q: 206  sednadgssgvtegaeagCYLASGSRDQTMRIWSTARRKGVMTL 249
           667778899999999999****************9998888876 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MHERHLPASP NWYCSRCSDI NSKGVFGFGA KNTVYLLNVT AASPAVTGEL AGHTERVSGF 60
AFCPNEGQEH ICCSTSDDKK VKIWDAEQKI LLKEHNVHQN TITAVHWSPV QKLLLVTGDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGTGTTTT CGGCAGCATG AGTACATGTG AGAAGTGATT TCACTGTCAC CATCCGCGAA 60
ATAATTTTTA TATTTGTTTA CACACTGTTT GCGGTTTATA ATGCACGAAA GACATCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

KEGG

dre:799538

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	63.67	0.00e+00	1049.00
IUUC-Apl-003586	Anas platyrhynchos	42.12	8.00e-146	511.00
IUUC-Aca-004956	Anolis carolinensis	65.15	0.00e+00	1054.00
IUUC-Ame-010753	Astyanax mexicanus	80.89	0.00e+00	1235.00
IUUC-Bta-012315	Bos taurus	51.66	0.00e+00	1466.00
IUUC-Cja-019334	Callithrix jacchus	51.62	0.00e+00	1484.00
IUUC-Cfa-021254	Canis familiaris	51.80	0.00e+00	1499.00
IUUC-Cpo-021984	Cavia porcellus	50.33	0.00e+00	1407.00
IUUC-Csa-023650	Chlorocebus sabaeus	51.52	0.00e+00	1460.00
IUUC-Cho-024860	Choloepus hoffmanni	55.23	0.00e+00	1281.00
IUUC-Cin-025778	Ciona intestinalis	41.00	5.00e-159	555.00
IUUC-Csv-026313	Ciona savignyi	41.10	3.00e-166	578.00
IUUC-Dno-029799	Dasypus novemcinctus	55.13	0.00e+00	1375.00
IUUC-Dor-030885	Dipodomys ordii	54.89	3.00e-113	404.00
IUUC-Ete-032918	Echinops telfairi	49.40	0.00e+00	1402.00
IUUC-Eca-034144	Equus caballus	51.34	0.00e+00	1471.00
IUUC-Eeu-034843	Erinaceus europaeus	48.80	0.00e+00	1034.00
IUUC-Fca-035948	Felis catus	50.98	0.00e+00	1456.00
IUUC-Fal-037303	Ficedula albicollis	55.11	0.00e+00	1441.00
IUUC-Gmo-039591	Gadus morhua	62.24	0.00e+00	954.00
IUUC-Gga-040570	Gallus gallus	49.96	0.00e+00	1297.00
IUUC-Gac-042646	Gasterosteus aculeatus	57.13	0.00e+00	1562.00
IUUC-Ggo-045605	Gorilla gorilla	49.16	0.00e+00	1097.00
IUUC-Hsa-046122	Homo sapiens	51.49	0.00e+00	1472.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	54.67	0.00e+00	1399.00
IUUC-Lch-050489	Latimeria chalumnae	47.59	0.00e+00	842.00
IUUC-Loc-052259	Lepisosteus oculatus	68.58	0.00e+00	1060.00
IUUC-Laf-053338	Loxodonta africana	51.13	0.00e+00	1482.00
IUUC-Mcc-055442	Macaca mulatta	51.66	0.00e+00	1464.00
IUUC-Meu-056245	Macropus eugenii	65.40	0.00e+00	691.00
IUUC-Mga-060202	Meleagris gallopavo	64.38	0.00e+00	890.00
IUUC-Mmr-061730	Microcebus murinus	50.53	0.00e+00	1459.00
IUUC-Mdo-062880	Monodelphis domestica	65.88	0.00e+00	1064.00
IUUC-Mmu-063930	Mus musculus	62.76	0.00e+00	1025.00
IUUC-Mpu-066605	Mustela putorius furo	51.05	0.00e+00	1471.00
IUUC-Mlu-067765	Myotis lucifugus	51.93	0.00e+00	1496.00
IUUC-Nle-069183	Nomascus leucogenys	52.17	0.00e+00	1450.00
IUUC-Opr-070659	Ochotona princeps	36.84	1.00e-93	338.00
IUUC-Ont-072356	Oreochromis niloticus	70.43	0.00e+00	1107.00
IUUC-Oan-073056	Ornithorhynchus anatinus	67.01	0.00e+00	1004.00
IUUC-Ocu-073881	Oryctolagus cuniculus	50.43	0.00e+00	1487.00
IUUC-Ola-087120	Oryzias latipes	59.02	9.00e-74	269.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.37	1.00e-31	132.00
IUUC-Oga-088343	Otolemur garnettii	51.03	0.00e+00	1476.00
IUUC-Oar-089257	Ovis aries	52.00	0.00e+00	1488.00
IUUC-Ptr-090497	Pan troglodytes	51.28	0.00e+00	1472.00
IUUC-Pan-092638	Papio anubis	51.25	0.00e+00	1450.00
IUUC-Psi-093096	Pelodiscus sinensis	52.66	0.00e+00	1304.00
IUUC-Pma-094571	Petromyzon marinus	46.25	1.00e-55	210.00
IUUC-Pfo-096348	Poecilia formosa	70.35	0.00e+00	1073.00
IUUC-Pab-098153	Pongo abelii	51.10	0.00e+00	1485.00
IUUC-Pca-100957	Procavia capensis	50.03	0.00e+00	1394.00
IUUC-Pva-102439	Pteropus vampyrus	51.92	0.00e+00	1491.00
IUUC-Rno-105891	Rattus norvegicus	62.21	0.00e+00	1016.00
IUUC-Sha-107181	Sarcophilus harrisii	53.62	0.00e+00	1470.00
IUUC-Ssc-115413	Sus scrofa	51.84	0.00e+00	1513.00
IUUC-Tgu-117082	Taeniopygia guttata	52.14	0.00e+00	1461.00
IUUC-Tru-118491	Takifugu rubripes	68.97	0.00e+00	1053.00
IUUC-Tsy-119629	Tarsius syrichta	65.74	4.00e-119	423.00
IUUC-Tni-120240	Tetraodon nigroviridis	68.61	0.00e+00	1041.00
IUUC-Tbe-127673	Tupaia belangeri	44.05	0.00e+00	1129.00
IUUC-Ttr-128562	Tursiops truncatus	49.29	0.00e+00	1389.00
IUUC-Vpa-130596	Vicugna pacos	53.92	0.00e+00	1198.00
IUUC-Xtr-132469	Xenopus tropicalis	51.00	0.00e+00	1439.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence