iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021894

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02052358

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000024908.1	ENSCPOT00000023690.1	ENSCPOP00000018898.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-79	268.0	2570	2930

Active Site

Position(s)	Description	Evidence
2904	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r+fl++++kelq+++l+l+       ++++++k+ l+p+p ++     +++l +flG+llg+a++
   Q: 2570 DPTYAFNIRFTGEEVHGTSGSFRHFLWQVCKELQSSSLSLLllcpssaVNKNKGKYILTPSPITY----GEEQLLHFLGQLLGIAIR 2652
           5667788*********************************9999999888888***********9....789*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelyks.lkeikenaesdieelgldltfs...vseei...............lge 150
            + +l+l+l +sf+k+l+g++l+  +dl+e d  +y++ +k+ + n+e+++e+l+++++++   v   +                 +
   Q: 2653 ADVPLPLDLLPSFWKTLVGEPLDPdQDLQEADILTYNYiKKFESINDETELEALCAEIASQhlaV---EspegpnkpccrftylTMT 2736
           **************************************666666777889999999999985422...2467999*******65555 PP
   S: 151  tkeeeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkyk 236
            +e+eL+++G++ipV++eNk+ Y  ++ ++rl+e + +e+v a+r+G+ ++ipl+ll+ +++ e+el +cG ++i++e lk++t+y+
   Q: 2737 GEEVELCSRGRHIPVAWENKDIYAAAIRSLRLRElQNTECVMAVRAGLGSIIPLQLLTTLSPLEMELRTCGLPYINLEFLKAHTMYQ 2823
           56667*****************************9**************************************************** PP
   S: 237  ggytedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkL 310
            g++e++++i++Fw +le f++ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC+++ kL
   Q: 2824 VGLMETDQHIEFFWGALETFTQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgtaGSPDSRYIRVETCMFMVKL 2910
           **********************************************99999999988888888889955555*************** PP
   S: 311  PeYsskeilkekLlyAieet 330
           P+Yss ei+ e+L++Ai+++
   Q: 2911 PQYSSLEIMLERLRCAIHYR 2930
           *****************986 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

PTEMNKMKEL ELLCSMKEVS FDGNDLENMV LSLREKFLQE VNSLIQKPSH PLAKTKTLVK 60
SLMNRAELLL HVTIAAQSGL TRSISGTPAE TPACKSASET KVISHAVRQP VFLRSMSAPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTACAGAAA TGGTGAATAT AACTTACAGA TGTGTTTATG GTATTCTTGC TTAAACTCTG 60
TTTTACAGGC CTTTATCCTG TCTTCTAAGA CAAGCCTGAG CAATTCAGAG AGAAAAATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	97.71	0.00e+00	2735.00
IUUC-Apl-004161	Anas platyrhynchos	93.92	0.00e+00	2673.00
IUUC-Aca-005341	Anolis carolinensis	94.12	0.00e+00	2688.00
IUUC-Ame-011574	Astyanax mexicanus	74.71	0.00e+00	2580.00
IUUC-Bta-012514	Bos taurus	93.64	0.00e+00	1895.00
IUUC-Cja-019148	Callithrix jacchus	97.31	0.00e+00	2679.00
IUUC-Cfa-020499	Canis familiaris	97.37	0.00e+00	2727.00
IUUC-Csa-023079	Chlorocebus sabaeus	97.58	0.00e+00	2731.00
IUUC-Cho-024415	Choloepus hoffmanni	97.44	0.00e+00	2721.00
IUUC-Dre-027452	Danio rerio	83.53	0.00e+00	2413.00
IUUC-Dno-029595	Dasypus novemcinctus	97.30	0.00e+00	2725.00
IUUC-Dor-030849	Dipodomys ordii	86.67	0.00e+00	1496.00
IUUC-Ete-032563	Echinops telfairi	86.87	0.00e+00	1384.00
IUUC-Eca-034202	Equus caballus	97.44	0.00e+00	2701.00
IUUC-Eeu-035175	Erinaceus europaeus	95.30	0.00e+00	1058.00
IUUC-Fca-036295	Felis catus	97.51	0.00e+00	2722.00
IUUC-Fal-037003	Ficedula albicollis	94.57	0.00e+00	2691.00
IUUC-Gmo-038579	Gadus morhua	84.90	0.00e+00	2408.00
IUUC-Gga-040961	Gallus gallus	93.90	0.00e+00	2677.00
IUUC-Gac-041899	Gasterosteus aculeatus	84.89	0.00e+00	2445.00
IUUC-Ggo-045099	Gorilla gorilla	97.65	0.00e+00	2733.00
IUUC-Hsa-046331	Homo sapiens	97.58	0.00e+00	2735.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	94.39	0.00e+00	2120.00
IUUC-Lch-049923	Latimeria chalumnae	90.24	0.00e+00	1149.00
IUUC-Loc-052630	Lepisosteus oculatus	87.84	0.00e+00	2014.00
IUUC-Laf-053394	Loxodonta africana	97.02	0.00e+00	2716.00
IUUC-Mcc-055763	Macaca mulatta	97.58	0.00e+00	2730.00
IUUC-Meu-056039	Macropus eugenii	92.74	0.00e+00	2482.00
IUUC-Mga-059500	Meleagris gallopavo	94.02	0.00e+00	2673.00
IUUC-Mmr-060868	Microcebus murinus	91.65	0.00e+00	2569.00
IUUC-Mdo-062772	Monodelphis domestica	94.64	0.00e+00	2628.00
IUUC-Mmu-063606	Mus musculus	97.09	0.00e+00	2749.00
IUUC-Mpu-065860	Mustela putorius furo	95.50	0.00e+00	2652.00
IUUC-Mlu-067376	Myotis lucifugus	96.96	0.00e+00	2731.00
IUUC-Nle-069693	Nomascus leucogenys	94.28	0.00e+00	2613.00
IUUC-Ont-072470	Oreochromis niloticus	84.65	0.00e+00	2431.00
IUUC-Oan-073693	Ornithorhynchus anatinus	94.63	0.00e+00	2676.00
IUUC-Ocu-074032	Oryctolagus cuniculus	97.02	0.00e+00	2704.00
IUUC-Ola-087433	Oryzias latipes	82.68	0.00e+00	1419.00
IUUC-Oga-088546	Otolemur garnettii	97.71	0.00e+00	2731.00
IUUC-Oar-089643	Ovis aries	90.66	0.00e+00	757.00
IUUC-Ptr-090504	Pan troglodytes	97.51	0.00e+00	2733.00
IUUC-Pan-092543	Papio anubis	97.65	0.00e+00	2736.00
IUUC-Psi-093952	Pelodiscus sinensis	93.27	0.00e+00	2604.00
IUUC-Pfo-096356	Poecilia formosa	84.40	0.00e+00	2428.00
IUUC-Pab-098240	Pongo abelii	97.30	0.00e+00	2713.00
IUUC-Pca-100994	Procavia capensis	97.81	0.00e+00	1680.00
IUUC-Pva-102263	Pteropus vampyrus	95.50	0.00e+00	2675.00
IUUC-Rno-104888	Rattus norvegicus	97.23	0.00e+00	2753.00
IUUC-Sha-106944	Sarcophilus harrisii	94.72	0.00e+00	2672.00
IUUC-Sar-113556	Sorex araneus	85.35	0.00e+00	950.00
IUUC-Ssc-116187	Sus scrofa	97.79	0.00e+00	2573.00
IUUC-Tgu-116655	Taeniopygia guttata	94.44	0.00e+00	2678.00
IUUC-Tru-118093	Takifugu rubripes	83.52	0.00e+00	2424.00
IUUC-Tni-119739	Tetraodon nigroviridis	82.59	0.00e+00	1444.00
IUUC-Tbe-127962	Tupaia belangeri	89.22	0.00e+00	1015.00
IUUC-Ttr-128819	Tursiops truncatus	87.61	0.00e+00	1980.00
IUUC-Vpa-130482	Vicugna pacos	95.01	0.00e+00	2597.00
IUUC-Xtr-132222	Xenopus tropicalis	90.57	0.00e+00	2544.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence