iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012457

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Protein inhibitor of activated STAT, 1

Genbank Nucleotide ID

DAAA02027922

Gene Name

PIAS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000005564.5	ENSBTAT00000047844.3	ENSBTAP00000045009.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.08	0.00e+00	1201.00	IUUC-Hsa-046146
E3 activity/RING/RING	28.85	6.00e-28	120.00	IUUC-Spo-108339

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

MADSAELKQM VMSLRVSELQ VLLGYAGRNK HGRKHELLTK ALHLLKAGCS PAVQMKIKEL 60
YRRRFPQKIM TPADLSIPNV HSSPMPATLS PSTIPQLTYD GHPASSPLLP VSLLGPKHEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACAGACGCA AGATGGCGGA CAGTGCGGAA CTAAAGGTAA AGCGCAGCTC GAATTCACTT 60
CTAATATTCG GCCGCGGAGA CGGCGCTGCT TGTGCCGGGG GGGATGGGTC CGACCCTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027227--PIAS1
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0016605--C:PML body
GO:0061665--F:SUMO ligase activity
GO:0008270--F:zinc ion binding
GO:0045444--P:fat cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033235--P:positive regulation of protein sumoylation
GO:0042127--P:regulation of cell proliferation

KEGG

bta:509231

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001984	Ailuropoda melanoleuca	99.07	0.00e+00	1186.00
IUUC-Apl-003376	Anas platyrhynchos	93.86	0.00e+00	1180.00
IUUC-Aca-004444	Anolis carolinensis	85.80	0.00e+00	1082.00
IUUC-Aly-006507	Arabidopsis lyrata	35.48	2.00e-14	75.10
IUUC-Ame-011812	Astyanax mexicanus	74.81	0.00e+00	809.00
IUUC-Bci-013700	Botrytis cinerea	29.49	2.00e-29	124.00
IUUC-Bol-015250	Brassica oleracea	27.75	2.00e-17	84.30
IUUC-Cel-018231	Caenorhabditis elegans	37.26	9.00e-50	191.00
IUUC-Cfa-020481	Canis familiaris	99.39	0.00e+00	1192.00
IUUC-Cpo-021940	Cavia porcellus	98.00	0.00e+00	1204.00
IUUC-Csa-023964	Chlorocebus sabaeus	99.08	0.00e+00	1189.00
IUUC-Cho-024812	Choloepus hoffmanni	81.38	0.00e+00	726.00
IUUC-Csv-026329	Ciona savignyi	38.51	8.00e-79	288.00
IUUC-Cne-026824	Cryptococcus neoformans	40.37	1.00e-19	91.70
IUUC-Cme-027209	Cyanidioschyzon merolae	33.33	5.00e-15	76.60
IUUC-Dre-027526	Danio rerio	76.28	0.00e+00	894.00
IUUC-Dno-029550	Dasypus novemcinctus	98.76	0.00e+00	1186.00
IUUC-Dor-030325	Dipodomys ordii	83.20	0.00e+00	717.00
IUUC-Dme-032018	Drosophila melanogaster	47.28	7.00e-101	361.00
IUUC-Ete-032366	Echinops telfairi	85.83	0.00e+00	682.00
IUUC-Eca-033639	Equus caballus	98.91	0.00e+00	1170.00
IUUC-Eeu-034994	Erinaceus europaeus	86.65	0.00e+00	675.00
IUUC-Fca-035986	Felis catus	99.07	0.00e+00	1172.00
IUUC-Fal-036926	Ficedula albicollis	94.47	0.00e+00	1122.00
IUUC-Gmo-039058	Gadus morhua	71.19	0.00e+00	825.00
IUUC-Gga-040755	Gallus gallus	93.57	0.00e+00	1181.00
IUUC-Gac-042204	Gasterosteus aculeatus	72.28	0.00e+00	842.00
IUUC-Ggo-044494	Gorilla gorilla	96.43	0.00e+00	1138.00
IUUC-Hsa-046146	Homo sapiens	99.08	0.00e+00	1189.00
IUUC-Itr-048994	Ictidomys tridecemlineatus	98.29	0.00e+00	1163.00
IUUC-Lch-049611	Latimeria chalumnae	84.57	0.00e+00	1040.00
IUUC-Loc-052851	Lepisosteus oculatus	77.69	0.00e+00	859.00
IUUC-Laf-053486	Loxodonta africana	97.20	0.00e+00	1147.00
IUUC-Mcc-055123	Macaca mulatta	99.08	0.00e+00	1189.00
IUUC-Meu-056556	Macropus eugenii	68.97	0.00e+00	761.00
IUUC-Mor-057185	Magnaporthe oryzae	31.86	2.00e-25	110.00
IUUC-Mga-059790	Meleagris gallopavo	96.21	0.00e+00	1061.00
IUUC-Mmr-060785	Microcebus murinus	98.76	0.00e+00	1172.00
IUUC-Mdo-061916	Monodelphis domestica	97.51	0.00e+00	1184.00
IUUC-Mmu-063170	Mus musculus	98.16	0.00e+00	1154.00
IUUC-Mpu-066609	Mustela putorius furo	99.39	0.00e+00	1192.00
IUUC-Mlu-067164	Myotis lucifugus	97.20	0.00e+00	1148.00
IUUC-Nle-070004	Nomascus leucogenys	99.08	0.00e+00	1189.00
IUUC-Opr-070738	Ochotona princeps	77.76	0.00e+00	810.00
IUUC-Ont-071607	Oreochromis niloticus	76.68	0.00e+00	842.00
IUUC-Oan-073567	Ornithorhynchus anatinus	90.06	0.00e+00	1141.00
IUUC-Ocu-073833	Oryctolagus cuniculus	98.31	0.00e+00	1153.00
IUUC-Ola-086471	Oryzias latipes	73.03	0.00e+00	875.00
IUUC-Oga-088527	Otolemur garnettii	97.85	0.00e+00	1154.00
IUUC-Oar-089470	Ovis aries	99.53	0.00e+00	1191.00
IUUC-Ptr-091086	Pan troglodytes	99.08	0.00e+00	1189.00
IUUC-Pan-092236	Papio anubis	99.08	0.00e+00	1189.00
IUUC-Psi-093900	Pelodiscus sinensis	92.70	0.00e+00	1150.00
IUUC-Pma-094693	Petromyzon marinus	65.38	1.00e-177	615.00
IUUC-Pfo-096236	Poecilia formosa	75.68	0.00e+00	861.00
IUUC-Pab-098400	Pongo abelii	99.08	0.00e+00	1188.00
IUUC-Pva-102327	Pteropus vampyrus	90.32	0.00e+00	1051.00
IUUC-Rno-105980	Rattus norvegicus	98.31	0.00e+00	1185.00
IUUC-Spo-108339	Schizosaccharomyces pombe	28.57	3.00e-28	120.00
IUUC-Stu-112120	Solanum tuberosum	36.61	1.00e-17	84.70
IUUC-Sar-113126	Sorex araneus	97.83	0.00e+00	1189.00
IUUC-Ssc-115394	Sus scrofa	99.46	0.00e+00	1068.00
IUUC-Tgu-117164	Taeniopygia guttata	92.56	0.00e+00	876.00
IUUC-Tru-117960	Takifugu rubripes	76.55	0.00e+00	835.00
IUUC-Tsy-119069	Tarsius syrichta	97.20	0.00e+00	1128.00
IUUC-Tni-120583	Tetraodon nigroviridis	73.94	0.00e+00	826.00
IUUC-Tbe-127466	Tupaia belangeri	87.77	1.00e-150	526.00
IUUC-Ttr-128717	Tursiops truncatus	92.01	0.00e+00	1058.00
IUUC-Vpa-130624	Vicugna pacos	95.08	0.00e+00	1073.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence