iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036063

Ensembl Protein ID

ENSFCAP00000023582.1

UniProt Accession

M3XAC9; M3XAC9_FELCA

Genbank Protein ID

ENSFCAP00000023582

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02020622

Gene Name

ANKIB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000022205.1	ENSFCAT00000030459.1	ENSFCAP00000023582.1

Status

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.80e-57	194.4	334	550

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++++sv e++v + C h+fC+ C++++l+lki+eg++++i+cpa++c++ ++ + i++ +v++e+ kry +++++++ve+++a+kw
   Q: 334  CDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIES-VVSKEMDKRYLQFDIKAFVENNPAIKW 422
           **************************************************************.79************************* PP
   S: 91   cpapdCslvvllekea..............eklevecekcgkefCveCkeewHeglsCkelkeklakteeek...........eeaeske 155
           cp+p+C+++v+l+k++              ++  v+c ++g+ fC+eC  e+He+++C+++k++l+k +e+k           e+a+++ 
   Q: 423  CPTPGCERAVRLTKQGsntsgsdtlsfpllRAPAVDC-GKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKpeelvgvseayEDAANCL 511
           **************98999999888885544444447.7789*****************************9****************** PP
   S: 156  lleanskkCpkCkvyieknegCnhmtC.akCkaefCwlC 193
           +l +nsk+C++Ck++i+knegCnhm+C +kCk++fCw+C
   Q: 512  WLLTNSKPCANCKSPIQKNEGCNHMQCaKKCKYDFCWIC 550
           ***************************889********* PP

Organism

Felis catus

Protein Sequence
(Fasta)

MGNTTTKFRK ALINGDENLA CQIYENNPQL KESLDPNISY GEPYQHNTPL HYAARHGMNR 60
ILGTFLFGRD GNPNKRNVHN ETSMHLLCMG PQIMISEGAL HPRLARPAED DFRRADCLQM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAAATA CAACCACCAA ATTCCGTAAA GCACTTATCA ATGGTGATGA AAACCTGGCC 60
TGCCAAATAT ATGAAAACAA CCCTCAGCTA AAAGAATCCC TTGATCCAAA TATATCTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR003903--UIM_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50330--UIM
PS50089--ZF_RING_2

Pfam

PF00023--Ank
PF01485--IBR

SMART

SM00248--ANK
SM00647--IBR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000970	Aegilops tauschii	29.07	1.00e-49	190.00
IUUC-Aml-002145	Ailuropoda melanoleuca	97.99	0.00e+00	2060.00
IUUC-Atr-002495	Amborella trichopoda	29.59	8.00e-50	191.00
IUUC-Apl-003749	Anas platyrhynchos	86.47	0.00e+00	1827.00
IUUC-Aca-004337	Anolis carolinensis	82.79	0.00e+00	1725.00
IUUC-Aly-006224	Arabidopsis lyrata	30.21	2.00e-60	226.00
IUUC-Ath-006859	Arabidopsis thaliana	28.54	1.00e-58	221.00
IUUC-Ame-011136	Astyanax mexicanus	71.67	0.00e+00	1516.00
IUUC-Bta-012896	Bos taurus	95.97	0.00e+00	1960.00
IUUC-Bol-015971	Brassica oleracea	30.15	5.00e-60	225.00
IUUC-Bra-017081	Brassica rapa	29.73	3.00e-58	219.00
IUUC-Cja-019418	Callithrix jacchus	95.24	0.00e+00	1931.00
IUUC-Cfa-021139	Canis familiaris	97.90	0.00e+00	2030.00
IUUC-Cpo-022432	Cavia porcellus	93.32	0.00e+00	1944.00
IUUC-Cre-022815	Chlamydomonas reinhardtii	28.99	6.00e-54	204.00
IUUC-Csa-023239	Chlorocebus sabaeus	95.79	0.00e+00	1978.00
IUUC-Cho-024329	Choloepus hoffmanni	86.00	0.00e+00	1168.00
IUUC-Dre-028543	Danio rerio	77.78	0.00e+00	1517.00
IUUC-Dno-028949	Dasypus novemcinctus	94.42	0.00e+00	1954.00
IUUC-Dor-031083	Dipodomys ordii	85.14	0.00e+00	961.00
IUUC-Ete-032919	Echinops telfairi	94.02	0.00e+00	769.00
IUUC-Eca-033459	Equus caballus	96.34	0.00e+00	1933.00
IUUC-Eeu-034726	Erinaceus europaeus	74.12	0.00e+00	704.00
IUUC-Fal-036854	Ficedula albicollis	84.05	0.00e+00	1764.00
IUUC-Gmo-039629	Gadus morhua	63.76	0.00e+00	1176.00
IUUC-Gga-040616	Gallus gallus	86.87	0.00e+00	1834.00
IUUC-Gac-042034	Gasterosteus aculeatus	73.96	0.00e+00	1449.00
IUUC-Gma-042954	Glycine max	29.81	1.00e-56	214.00
IUUC-Ggo-045104	Gorilla gorilla	96.16	0.00e+00	1974.00
IUUC-Hsa-046209	Homo sapiens	96.07	0.00e+00	1967.00
IUUC-Hvu-047322	Hordeum vulgare	28.63	1.00e-54	207.00
IUUC-Itr-047991	Ictidomys tridecemlineatus	93.28	0.00e+00	1037.00
IUUC-Lch-050129	Latimeria chalumnae	79.48	0.00e+00	1525.00
IUUC-Lpe-051492	Leersia perrieri	29.52	1.00e-56	214.00
IUUC-Loc-052381	Lepisosteus oculatus	77.42	0.00e+00	1563.00
IUUC-Laf-053411	Loxodonta africana	95.97	0.00e+00	1977.00
IUUC-Mcc-055098	Macaca mulatta	95.54	0.00e+00	1805.00
IUUC-Mtr-058263	Medicago truncatula	30.11	3.00e-57	216.00
IUUC-Mga-059352	Meleagris gallopavo	86.53	0.00e+00	1827.00
IUUC-Mmr-061763	Microcebus murinus	94.03	0.00e+00	1964.00
IUUC-Mdo-062522	Monodelphis domestica	93.61	0.00e+00	1585.00
IUUC-Mmu-063322	Mus musculus	92.68	0.00e+00	1934.00
IUUC-Mac-065497	Musa acuminata	29.46	1.00e-57	218.00
IUUC-Mpu-065807	Mustela putorius furo	97.99	0.00e+00	2023.00
IUUC-Mlu-067421	Myotis lucifugus	92.96	0.00e+00	1895.00
IUUC-Nle-069468	Nomascus leucogenys	96.07	0.00e+00	1966.00
IUUC-Opr-070381	Ochotona princeps	86.69	0.00e+00	1815.00
IUUC-Ont-072092	Oreochromis niloticus	71.97	0.00e+00	1480.00
IUUC-Oan-072962	Ornithorhynchus anatinus	87.32	0.00e+00	673.00
IUUC-Ocu-074462	Oryctolagus cuniculus	91.67	0.00e+00	1835.00
IUUC-Oba-075918	Oryza barthii	33.62	1.00e-55	211.00
IUUC-Obr-076705	Oryza brachyantha	28.90	7.00e-56	211.00
IUUC-Ogl-077640	Oryza glaberrima	29.13	1.00e-56	214.00
IUUC-Ogu-079025	Oryza glumaepatula	33.62	3.00e-55	209.00
IUUC-Oin-079448	Oryza indica	29.13	2.00e-56	213.00
IUUC-Olo-080626	Oryza longistaminata	33.95	2.00e-48	187.00
IUUC-Ome-081812	Oryza meridionalis	33.62	6.00e-56	211.00
IUUC-Oni-082202	Oryza nivara	29.19	1.00e-54	207.00
IUUC-Opu-084059	Oryza punctata	33.90	1.00e-55	211.00
IUUC-Oru-084181	Oryza rufipogon	33.62	2.00e-55	210.00
IUUC-Osa-086069	Oryza sativa	33.62	3.00e-55	209.00
IUUC-Ola-086873	Oryzias latipes	76.31	0.00e+00	1457.00
IUUC-Oga-088058	Otolemur garnettii	96.98	0.00e+00	1997.00
IUUC-Oar-089724	Ovis aries	96.16	0.00e+00	1963.00
IUUC-Ptr-090646	Pan troglodytes	96.07	0.00e+00	1966.00
IUUC-Pan-092334	Papio anubis	95.79	0.00e+00	1979.00
IUUC-Psi-093827	Pelodiscus sinensis	86.69	0.00e+00	1793.00
IUUC-Pma-094243	Petromyzon marinus	62.12	0.00e+00	901.00
IUUC-Ppa-095545	Physcomitrella patens	29.80	2.00e-57	216.00
IUUC-Pfo-097370	Poecilia formosa	69.63	0.00e+00	1451.00
IUUC-Pab-098757	Pongo abelii	95.97	0.00e+00	1994.00
IUUC-Pop-099139	Populus trichocarpa	29.73	9.00e-58	218.00
IUUC-Pca-101017	Procavia capensis	88.59	0.00e+00	941.00
IUUC-Ppe-101451	Prunus persica	35.71	3.00e-57	216.00
IUUC-Pva-102797	Pteropus vampyrus	94.43	0.00e+00	1933.00
IUUC-Rno-106046	Rattus norvegicus	93.50	0.00e+00	1951.00
IUUC-Sha-107341	Sarcophilus harrisii	87.04	0.00e+00	1848.00
IUUC-Smo-109424	Selaginella moellendorffii	30.15	5.00e-57	215.00
IUUC-Sly-111454	Solanum lycopersicum	28.04	8.00e-58	218.00
IUUC-Stu-112533	Solanum tuberosum	27.31	8.00e-57	214.00
IUUC-Sar-113328	Sorex araneus	86.02	0.00e+00	1493.00
IUUC-Sbi-114839	Sorghum bicolor	29.25	8.00e-56	211.00
IUUC-Ssc-115681	Sus scrofa	95.53	0.00e+00	1955.00
IUUC-Tgu-116830	Taeniopygia guttata	86.51	0.00e+00	1819.00
IUUC-Tru-117711	Takifugu rubripes	73.46	0.00e+00	1410.00
IUUC-Tsy-119501	Tarsius syrichta	84.69	0.00e+00	890.00
IUUC-Tni-119911	Tetraodon nigroviridis	64.96	0.00e+00	1208.00
IUUC-Tca-121539	Theobroma cacao	29.11	2.00e-54	206.00
IUUC-Tae-123155	Triticum aestivum	28.99	2.00e-54	206.00
IUUC-Tur-126178	Triticum urartu	29.90	2.00e-44	174.00
IUUC-Tbe-127647	Tupaia belangeri	84.56	0.00e+00	1214.00
IUUC-Ttr-129218	Tursiops truncatus	96.89	0.00e+00	2017.00
IUUC-Vpa-130603	Vicugna pacos	96.43	0.00e+00	1974.00
IUUC-Vvi-131543	Vitis vinifera	28.21	2.00e-54	207.00
IUUC-Xtr-132250	Xenopus tropicalis	78.89	0.00e+00	1015.00
IUUC-Xma-133029	Xiphophorus maculatus	69.58	0.00e+00	1467.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence