iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096126

Ensembl Protein ID

ENSPFOP00000012370.2

UniProt Accession

A0A087Y2W7; A0A087Y2W7_POEFO

Genbank Protein ID

ENSPFOP00000012370

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AYCK01013148

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000012238.2	ENSPFOT00000012387.2	ENSPFOP00000012370.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.70e-10	41.3	13	67

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            + + y+++++++ +L ++kGdv+++i   ++d +W  + k+++g++G +P+n+v+k
   Q: 13   ECVARYNFKGTSEQDLPFNKGDVLTII-VVTKDPNWYHA-KNAAGQEGTIPANYVQK 67
           68899**********************.9**********.7**************87 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MTEVQSPWPQ GTECVARYNF KGTSEQDLPF NKGDVLTIIV VTKDPNWYHA KNAAGQEGTI 60
PANYVQKREG VKSGGKLSLM PWFHGKITRD QAEQLLDPPE TGLFLVREST NFPGDYTLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACCAGCTC TGATGGTAGC AGGGAGAACA CCTCACCTGT GAGAGGATCC AAGAACCTCA 60
CCATGACAGA GGTCCAGGTA ATTTAGAAAC TTTGACCTCA AACACTGGCG TTTGTCAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004391	Anolis carolinensis	83.30	0.00e+00	788.00
IUUC-Cin-025513	Ciona intestinalis	54.94	4.00e-145	508.00
IUUC-Csv-025899	Ciona savignyi	50.97	8.00e-135	473.00
IUUC-Fal-037215	Ficedula albicollis	83.67	0.00e+00	796.00
IUUC-Gmo-039103	Gadus morhua	85.94	0.00e+00	796.00
IUUC-Gga-040506	Gallus gallus	83.22	0.00e+00	793.00
IUUC-Loc-052586	Lepisosteus oculatus	87.47	0.00e+00	825.00
IUUC-Meu-056387	Macropus eugenii	83.75	0.00e+00	792.00
IUUC-Mtr-058657	Medicago truncatula	28.79	6.00e-19	89.40
IUUC-Mga-060040	Meleagris gallopavo	81.94	0.00e+00	772.00
IUUC-Mdo-061871	Monodelphis domestica	83.52	0.00e+00	790.00
IUUC-Ont-072457	Oreochromis niloticus	95.96	0.00e+00	899.00
IUUC-Ola-087105	Oryzias latipes	94.39	0.00e+00	887.00
IUUC-Oga-087928	Otolemur garnettii	82.84	0.00e+00	785.00
IUUC-Sha-106987	Sarcophilus harrisii	83.75	0.00e+00	794.00
IUUC-Tru-118712	Takifugu rubripes	91.65	0.00e+00	860.00
IUUC-Tni-119856	Tetraodon nigroviridis	91.28	0.00e+00	861.00
IUUC-Xtr-132763	Xenopus tropicalis	79.51	0.00e+00	758.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence