iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093992

Ensembl Protein ID

ENSPSIP00000005143.1

UniProt Accession

K7FAT3; K7FAT3_PELSI

Genbank Protein ID

ENSPSIP00000005143

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01092838

Gene Name

EP300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000004772.1	ENSPSIT00000005172.1	ENSPSIP00000005143.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	82.94	0.00e+00	1973.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MAENVVEPGP PSAKRPKLSS PALSVSASDG TDFGSLFDLE HDLPDELISS TDLVLTNGGD 60
INQLQNTIGI AQDAASKHKQ LSELLRAGSS PNLNMGVGGP AQGMASQTQQ NSPGMGILNS 120

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Nucleotide Sequence
(Fasta)

ATGGCCGAGA ATGTGGTGGA GCCGGGCCCG CCTTCAGCCA AGCGGCCTAA ACTCTCCTCA 60
CCGGCGCTCT CCGTGTCCGC AAGCGATGGC ACAGGTCAGT CTCAGGGGCC CAGACCCCCC 120

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Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR009110--Nuc_rcpt_coact
IPR014744--Nuc_rcpt_coact_CREBbp
IPR010303--RING_CBP-p300
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF09030--Creb_binding
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001156	Aegilops tauschii	37.40	7.00e-68	253.00
IUUC-Aml-002027	Ailuropoda melanoleuca	86.28	0.00e+00	1776.00
IUUC-Apl-003917	Anas platyrhynchos	81.76	0.00e+00	1453.00
IUUC-Aca-005040	Anolis carolinensis	85.49	0.00e+00	1810.00
IUUC-Ath-007233	Arabidopsis thaliana	37.88	2.00e-74	274.00
IUUC-Ame-011395	Astyanax mexicanus	80.86	0.00e+00	1486.00
IUUC-Bta-012649	Bos taurus	83.12	0.00e+00	1855.00
IUUC-Bdi-014481	Brachypodium distachyon	38.83	2.00e-71	265.00
IUUC-Bol-016000	Brassica oleracea	38.83	6.00e-74	273.00
IUUC-Bra-018090	Brassica rapa	38.83	3.00e-74	273.00
IUUC-Cel-018691	Caenorhabditis elegans	50.25	0.00e+00	841.00
IUUC-Cja-019649	Callithrix jacchus	83.49	0.00e+00	1891.00
IUUC-Cfa-020764	Canis familiaris	90.08	0.00e+00	1693.00
IUUC-Cpo-022345	Cavia porcellus	84.86	0.00e+00	1884.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	34.84	3.00e-65	243.00
IUUC-Csa-023866	Chlorocebus sabaeus	87.08	0.00e+00	1778.00
IUUC-Cho-024951	Choloepus hoffmanni	92.12	0.00e+00	1174.00
IUUC-Cin-025624	Ciona intestinalis	61.58	0.00e+00	1070.00
IUUC-Csv-026122	Ciona savignyi	64.75	0.00e+00	678.00
IUUC-Dre-028500	Danio rerio	79.54	0.00e+00	1484.00
IUUC-Dno-029638	Dasypus novemcinctus	80.43	0.00e+00	1454.00
IUUC-Dor-030279	Dipodomys ordii	80.75	0.00e+00	1207.00
IUUC-Dme-031716	Drosophila melanogaster	71.06	0.00e+00	783.00
IUUC-Ete-032979	Echinops telfairi	81.42	0.00e+00	1644.00
IUUC-Eca-034048	Equus caballus	87.32	0.00e+00	1767.00
IUUC-Eeu-035154	Erinaceus europaeus	81.13	0.00e+00	1349.00
IUUC-Fca-035891	Felis catus	87.49	0.00e+00	1773.00
IUUC-Fal-037585	Ficedula albicollis	93.31	0.00e+00	1916.00
IUUC-Gmo-039348	Gadus morhua	84.78	0.00e+00	1452.00
IUUC-Gga-040916	Gallus gallus	92.88	0.00e+00	1953.00
IUUC-Gac-041642	Gasterosteus aculeatus	87.08	0.00e+00	1415.00
IUUC-Ggo-045189	Gorilla gorilla	87.00	0.00e+00	1770.00
IUUC-Hsa-046884	Homo sapiens	87.00	0.00e+00	1769.00
IUUC-Hvu-047619	Hordeum vulgare	37.40	8.00e-68	253.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	87.73	0.00e+00	1733.00
IUUC-Loc-052536	Lepisosteus oculatus	86.79	0.00e+00	1448.00
IUUC-Laf-054423	Loxodonta africana	86.22	0.00e+00	1831.00
IUUC-Mcc-054847	Macaca mulatta	87.00	0.00e+00	1777.00
IUUC-Meu-056217	Macropus eugenii	86.77	0.00e+00	1847.00
IUUC-Mtr-058740	Medicago truncatula	38.01	7.00e-68	253.00
IUUC-Mga-059250	Meleagris gallopavo	91.16	0.00e+00	1920.00
IUUC-Mmr-061496	Microcebus murinus	87.16	0.00e+00	1786.00
IUUC-Mdo-062478	Monodelphis domestica	88.42	0.00e+00	1983.00
IUUC-Mmu-063456	Mus musculus	85.74	0.00e+00	1764.00
IUUC-Mac-064767	Musa acuminata	39.60	8.00e-76	279.00
IUUC-Mpu-065963	Mustela putorius furo	84.12	0.00e+00	1762.00
IUUC-Mlu-067185	Myotis lucifugus	86.70	0.00e+00	1750.00
IUUC-Ncr-068795	Neurospora crassa	39.24	5.00e-14	72.00
IUUC-Nle-069907	Nomascus leucogenys	87.48	0.00e+00	1738.00
IUUC-Opr-070324	Ochotona princeps	76.13	0.00e+00	1033.00
IUUC-Ont-072211	Oreochromis niloticus	79.68	0.00e+00	1479.00
IUUC-Oan-073723	Ornithorhynchus anatinus	90.73	0.00e+00	1924.00
IUUC-Ocu-074707	Oryctolagus cuniculus	86.52	0.00e+00	1754.00
IUUC-Oba-075590	Oryza barthii	33.61	1.00e-103	372.00
IUUC-Ogu-078580	Oryza glumaepatula	33.47	7.00e-104	372.00
IUUC-Oin-079283	Oryza indica	38.83	1.00e-73	271.00
IUUC-Olo-080969	Oryza longistaminata	38.83	2.00e-73	271.00
IUUC-Ome-081615	Oryza meridionalis	33.61	1.00e-103	371.00
IUUC-Oni-082636	Oryza nivara	33.61	1.00e-103	371.00
IUUC-Opu-084073	Oryza punctata	38.83	4.00e-74	273.00
IUUC-Oru-084994	Oryza rufipogon	33.61	1.00e-103	371.00
IUUC-Osa-085860	Oryza sativa	41.94	1.00e-62	235.00
IUUC-Ola-086899	Oryzias latipes	77.83	0.00e+00	1416.00
IUUC-Olu-087701	Ostreococcus lucimarinus	35.19	2.00e-62	234.00
IUUC-Oga-088700	Otolemur garnettii	86.69	0.00e+00	1782.00
IUUC-Oar-089787	Ovis aries	85.40	0.00e+00	1774.00
IUUC-Ptr-091620	Pan troglodytes	87.00	0.00e+00	1771.00
IUUC-Pan-092166	Papio anubis	84.32	0.00e+00	1878.00
IUUC-Pma-094328	Petromyzon marinus	85.67	0.00e+00	1001.00
IUUC-Ppa-095569	Physcomitrella patens	38.23	2.00e-71	264.00
IUUC-Pfo-097342	Poecilia formosa	84.91	0.00e+00	1389.00
IUUC-Pab-098235	Pongo abelii	86.28	0.00e+00	1774.00
IUUC-Pop-098947	Populus trichocarpa	40.00	6.00e-74	273.00
IUUC-Pca-100780	Procavia capensis	85.10	0.00e+00	1401.00
IUUC-Ppe-101498	Prunus persica	37.19	4.00e-67	249.00
IUUC-Pva-103071	Pteropus vampyrus	86.76	0.00e+00	1818.00
IUUC-Sha-106736	Sarcophilus harrisii	92.28	0.00e+00	1677.00
IUUC-Smo-109420	Selaginella moellendorffii	38.01	1.00e-71	265.00
IUUC-Sit-110128	Setaria italica	38.69	2.00e-72	268.00
IUUC-Stu-112845	Solanum tuberosum	37.08	6.00e-64	238.00
IUUC-Sar-113162	Sorex araneus	83.83	0.00e+00	772.00
IUUC-Sbi-114827	Sorghum bicolor	39.09	7.00e-74	273.00
IUUC-Ssc-116077	Sus scrofa	86.37	0.00e+00	1794.00
IUUC-Tgu-116872	Taeniopygia guttata	93.92	0.00e+00	1921.00
IUUC-Tru-118047	Takifugu rubripes	50.72	4.00e-109	390.00
IUUC-Tsy-119451	Tarsius syrichta	79.37	0.00e+00	1230.00
IUUC-Tca-121835	Theobroma cacao	39.14	2.00e-73	271.00
IUUC-Tvi-122536	Trichoderma virens	44.30	6.00e-16	78.20
IUUC-Tae-124383	Triticum aestivum	38.48	1.00e-68	255.00
IUUC-Tur-126284	Triticum urartu	37.66	2.00e-68	254.00
IUUC-Tbe-127772	Tupaia belangeri	77.83	0.00e+00	1189.00
IUUC-Ttr-128447	Tursiops truncatus	80.65	0.00e+00	1463.00
IUUC-Vpa-130766	Vicugna pacos	91.16	0.00e+00	1148.00
IUUC-Xtr-131854	Xenopus tropicalis	81.59	0.00e+00	1800.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence