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Tag Content
UUCD2 ID IUUC-Fca-035876
UUCD1 version UUC-FeC-00787
Ensembl Protein ID ENSFCAP00000000196.3
UniProt Accession M3VUA8; M3VUA8_FELCA
Genbank Protein ID ENSFCAP00000000196
Protein Name Uncharacterized protein
Genbank Nucleotide ID AANG02028059
Gene Name USP25
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000000211.3 ENSFCAT00000000211.3 ENSFCAP00000000196.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.50e-63 215.0 154 639
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+r+l+l+    ++ ++l+++++++++ +++++l+ lf+ l+ +k+k+v+p++ +++lk++ ++ +
   Q: 154  VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNykppSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRAVEILKDAFKS-N 241
           6******************************99988889999999999999*******************************99997.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
            ++qqD++Ef++ lld le+++++                  + +ee +++k k+++++lF g++    + +  +++ + +e f +++l
   Q: 242  DSQQQDVSEFTHKLLDWLEDAFQM------------------KAEEEMDEEKPKNPMVELFYGRFLAVGVLE--GKKFENTEMFGQYPL 310
           **********************33..................122345788999************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    ++++++klP+vL+++L+Rf+f+++ +++eki++k+efp+ L l++
   Q: 311  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSGKS---GQEHWFTKLPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDR 388
           ******.....9**************96...999998865...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++++                                                                                     
   Q: 389  YMHRnreitrikreeikrlkdyltvlqqrlerylsygsgpkrfplvdvlqyalefasskpvctspvddidassppsgsipqtlpstteq 477
           ****8888888888888888888888888888888888877777777777777777777777777777777777777777777655555 PP
   S: 268  ...peekqke............................................................................... 274
              p     +                                                                               
   Q: 478  qgaP-----Saelpstspaplaavssrsvihkpftqsrippdlpmhpaprhiteeelsvlesclhrwrteiendtrdlqesisrihrti 561
           5550.....05555555555555555556666666666666666666666666666666667777777777777777777888888888 PP
   S: 275  ..........kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                     ++ Y+L+av+vH+G+++ GHY+ay+ +++++ W++++D  Vt++++ee ++++      ++aY+l+Y 
   Q: 562  elmysdksmiQVPYRLHAVLVHEGQANAGHYWAYIFDHRENrWMKYNDIAVTKSSWEELVRDSFggyrnASAYCLMYI 639
           8888888888**************************965556***************99997779************6 PP
   
Organism Felis catus
Protein Sequence
(Fasta)
HQQTFLNQLR EITGINDAQI LQQALKDSNG NLELAVAFLT AKNAKTPQQE ETTYYQTALP 60
GNDRYISVGS QADTNVIDLT GDDKDDLQRA IALSLAESNR AFRETGITDE EQAISRVLEA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fca-035876|DUB,USP|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATTTCGTTTT TTCTCCTCTA GCACCAGCAG ACATTTCTGA ATCAGCTGAG AGAAATCACT 60
GGGATTAATG ATGCCCAGAT ACTTCAGCAA GCCTTGAAGG TATGGCCGCT GTTTTATGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fca-035876|DUB,USP|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904293--P:negative regulation of ERAD pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001340 Ailuropoda melanoleuca 95.89 0.00e+00 1999.00
IUUC-Apl-004030 Anas platyrhynchos 83.57 0.00e+00 1823.00
IUUC-Aca-004753 Anolis carolinensis 65.52 0.00e+00 998.00
IUUC-Acl-008164 Aspergillus clavatus 23.88 1.00e-14 76.30
IUUC-Afu-008871 Aspergillus fumigatus 23.78 3.00e-14 74.70
IUUC-Ani-009503 Aspergillus nidulans 32.82 6.00e-12 67.00
IUUC-Ame-010624 Astyanax mexicanus 70.94 0.00e+00 1089.00
IUUC-Bta-013166 Bos taurus 97.11 0.00e+00 1973.00
IUUC-Cel-018346 Caenorhabditis elegans 27.41 9.00e-29 122.00
IUUC-Cja-019150 Callithrix jacchus 97.38 0.00e+00 1430.00
IUUC-Cfa-020649 Canis familiaris 98.56 0.00e+00 1466.00
IUUC-Cpo-021807 Cavia porcellus 93.46 0.00e+00 2046.00
IUUC-Csa-023388 Chlorocebus sabaeus 97.64 0.00e+00 1460.00
IUUC-Cho-024343 Choloepus hoffmanni 85.01 0.00e+00 1001.00
IUUC-Cin-025302 Ciona intestinalis 37.17 7.00e-97 347.00
IUUC-Csv-025911 Ciona savignyi 35.13 4.00e-131 462.00
IUUC-Cgl-026575 Colletotrichum gloeosporioides 55.32 1.00e-10 62.40
IUUC-Cme-027167 Cyanidioschyzon merolae 25.96 2.00e-19 91.70
IUUC-Dre-028016 Danio rerio 77.46 0.00e+00 1180.00
IUUC-Dno-029495 Dasypus novemcinctus 93.43 0.00e+00 1431.00
IUUC-Dor-030948 Dipodomys ordii 81.91 0.00e+00 1430.00
IUUC-Eca-033214 Equus caballus 96.36 0.00e+00 966.00
IUUC-Fal-036762 Ficedula albicollis 84.23 0.00e+00 1119.00
IUUC-Fox-037752 Fusarium oxysporum 25.42 2.00e-14 74.70
IUUC-Gmo-039490 Gadus morhua 72.55 0.00e+00 1522.00
IUUC-Gga-040817 Gallus gallus 86.13 0.00e+00 1353.00
IUUC-Gac-042473 Gasterosteus aculeatus 72.33 0.00e+00 1554.00
IUUC-Ggo-044939 Gorilla gorilla 93.00 0.00e+00 1911.00
IUUC-Hsa-046204 Homo sapiens 97.60 0.00e+00 1976.00
IUUC-Kpa-049349 Komagataella pastoris 27.60 1.00e-09 59.30
IUUC-Lch-049572 Latimeria chalumnae 78.95 0.00e+00 1218.00
IUUC-Loc-052070 Lepisosteus oculatus 75.87 0.00e+00 1198.00
IUUC-Laf-054426 Loxodonta africana 97.31 0.00e+00 1862.00
IUUC-Mcc-055858 Macaca mulatta 97.77 0.00e+00 1463.00
IUUC-Mga-059808 Meleagris gallopavo 86.24 0.00e+00 1835.00
IUUC-Mmr-060987 Microcebus murinus 96.99 0.00e+00 1415.00
IUUC-Mmu-064245 Mus musculus 93.46 0.00e+00 1961.00
IUUC-Mpu-066304 Mustela putorius furo 98.43 0.00e+00 1461.00
IUUC-Mlu-067139 Myotis lucifugus 96.15 0.00e+00 2025.00
IUUC-Nfi-068458 Neosartorya fischeri 23.54 1.00e-16 82.80
IUUC-Nle-069075 Nomascus leucogenys 97.60 0.00e+00 1971.00
IUUC-Ont-072150 Oreochromis niloticus 75.06 0.00e+00 1172.00
IUUC-Oan-073054 Ornithorhynchus anatinus 80.15 0.00e+00 1683.00
IUUC-Ocu-074102 Oryctolagus cuniculus 93.81 0.00e+00 1437.00
IUUC-Ola-086529 Oryzias latipes 69.66 0.00e+00 1483.00
IUUC-Oga-088939 Otolemur garnettii 96.44 0.00e+00 1981.00
IUUC-Oar-090266 Ovis aries 96.72 0.00e+00 1436.00
IUUC-Ptr-090546 Pan troglodytes 97.40 0.00e+00 1971.00
IUUC-Pan-092311 Papio anubis 97.64 0.00e+00 1462.00
IUUC-Psi-093459 Pelodiscus sinensis 90.85 0.00e+00 1182.00
IUUC-Pfo-096726 Poecilia formosa 74.94 0.00e+00 1155.00
IUUC-Pab-097608 Pongo abelii 94.68 0.00e+00 1954.00
IUUC-Pca-100718 Procavia capensis 92.32 0.00e+00 1260.00
IUUC-Pva-103150 Pteropus vampyrus 92.83 0.00e+00 1492.00
IUUC-Pte-104300 Pyrenophora teres 23.73 2.00e-14 75.10
IUUC-Pyt-104434 Pyrenophora triticirepentis 23.87 2.00e-14 75.10
IUUC-Rno-105727 Rattus norvegicus 94.04 0.00e+00 1920.00
IUUC-Sha-107051 Sarcophilus harrisii 89.51 0.00e+00 1874.00
IUUC-Sar-113097 Sorex araneus 87.11 0.00e+00 1846.00
IUUC-Sre-115145 Sporisorium reilianum 23.66 3.00e-11 65.10
IUUC-Ssc-115877 Sus scrofa 94.69 0.00e+00 1961.00
IUUC-Tgu-117473 Taeniopygia guttata 79.40 0.00e+00 1693.00
IUUC-Tru-118135 Takifugu rubripes 67.41 0.00e+00 1387.00
IUUC-Tsy-119471 Tarsius syrichta 89.89 0.00e+00 1803.00
IUUC-Tni-120139 Tetraodon nigroviridis 68.28 0.00e+00 1303.00
IUUC-Tbe-127549 Tupaia belangeri 90.57 0.00e+00 1892.00
IUUC-Ttr-128896 Tursiops truncatus 90.66 0.00e+00 1885.00
IUUC-Vpa-130500 Vicugna pacos 92.60 0.00e+00 1328.00
IUUC-Xtr-132896 Xenopus tropicalis 81.21 0.00e+00 1736.00
Created Date 25-Jun-2017

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