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Tag Content
UUCD2 ID IUUC-Bta-012552
UUCD1 version UUC-BoT-01134
Ensembl Protein ID ENSBTAP00000027254.4
UniProt Accession F1MKU4; F1MKU4_BOVIN
Genbank Protein ID ENSBTAP00000027254
Protein Name Ubiquitin carboxyl-terminal hydrolase 1
Genbank Nucleotide ID DAAA02008676
Gene Name USP1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000020451.4 ENSBTAT00000027254.4 ENSBTAP00000027254.4
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.50e-84 283.0 81 782
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l++e+++++kg          el++slq+l+ ++       +     
   Q: 81   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHlfniisRKKEALKDEANQKDKGnckedslasyELICSLQSLIISVeqlqasfLlnpek 169
           6************************************999999999999999999999*****99999999999995555555144555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk...............eknkpkeeeeeedkselsde...... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                 ++ +kee+++        +      
   Q: 170  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLECILGNIQETCQLlkkeevknvedlstkVEEYQKEEMSD--------Nnsmemd 250
           88888*****************************************5555666665555543222222222223........2555555 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 251  nmrhsedykeklskgngkrksdaefgnmkkkvkiskehqsseenqrqtrskrkaagdtleishkiipkhisenestrpsqrkskvkinw 339
           77*************************************************************************************** PP
   S: 130  ........................................................................aeekkkkknk.....sl 141
                                                                                         +k+      +l
   Q: 340  lksaakqpsilskfcsmgkiatnqgskghckeneydleedlgkyendnttndcelespgnndmpihvnevkpI-----NKGAeqigfEL 423
           *****************************************************************99554443.....444445555** PP
   S: 142  isdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqe 216
           +++lFqgql  +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c++++e
   Q: 424  VEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEenseispepktemkTLRWAISQFASVERIVGEDKYFCENCHHYTE 512
           ***************************************99998********************************************* PP
   S: 217  aekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayv 299
           ae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGHY+a v
   Q: 513  AERSLLFDKMPEVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGHYTASV 596
           ********************************************************99.....678*********************** PP
   S: 300  kn....................................................................................... 301
           k                                                                                        
   Q: 597  KVtdlnsleldkenfvidqtceigkpeplneeevrgvvenydneevsirvsgnnqpskvlnkknveaigllggqkskadyelynkasnp 685
           ***************************************************************************************** PP
   S: 302  .......................................................ekgkWllfdDskVtevkeeevleetg......st 329
                                                                   +gkWllfdDs+V++++e+++l++ +      st
   Q: 686  dkvastalpenrnsetnntngtdesdsnkessdqtginisgfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpstsptST 774
           *******************9999999999999999999999888888888877766999*******************888******** PP
   S: 330  aYvlfYkr 337
           +Y+lfYk+
   Q: 775  PYLLFYKK 782
           ******97 PP
   
Organism Bos taurus
Protein Sequence
(Fasta)
MPGVIPSESN GLSRGSPSKK NRLSLKFFQK KETKRALDFT DSQENEEKTS EYKGSEIDQV 60
VPAAQSSPIN CEKRENLLPF VGLNNLGNTC YLNSILQVLY FCPGFKSGVK HLFNIISRKK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012552|DUB,USP|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGCCGCTCC GGGGATGTAG TTGGTGCCCG CGCCAGGCAG GACCGAGCTG CAGCCCGGGT 60
TCCCGCTCTT GAGCGCGAAT GGTCACTTCC CCCGGGGAGG GCGATCGGGT CAGCTTTTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012552|DUB,USP|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001939 Ailuropoda melanoleuca 92.49 0.00e+00 1401.00
IUUC-Apl-004204 Anas platyrhynchos 71.49 0.00e+00 924.00
IUUC-Aca-004637 Anolis carolinensis 64.22 0.00e+00 922.00
IUUC-Ame-011718 Astyanax mexicanus 48.19 8.00e-173 600.00
IUUC-Cja-019588 Callithrix jacchus 91.97 0.00e+00 1429.00
IUUC-Cfa-020211 Canis familiaris 92.74 0.00e+00 1414.00
IUUC-Cpo-021551 Cavia porcellus 81.74 0.00e+00 1248.00
IUUC-Csa-024186 Chlorocebus sabaeus 92.36 0.00e+00 1438.00
IUUC-Cho-024739 Choloepus hoffmanni 80.60 0.00e+00 727.00
IUUC-Dre-028184 Danio rerio 48.90 3.00e-176 611.00
IUUC-Dno-029669 Dasypus novemcinctus 88.68 0.00e+00 1363.00
IUUC-Dor-030168 Dipodomys ordii 83.90 0.00e+00 1208.00
IUUC-Dme-031732 Drosophila melanogaster 30.94 2.00e-18 88.20
IUUC-Ete-032825 Echinops telfairi 85.24 0.00e+00 941.00
IUUC-Eca-033595 Equus caballus 90.25 0.00e+00 1296.00
IUUC-Eeu-034877 Erinaceus europaeus 79.55 6.00e-161 561.00
IUUC-Fca-035381 Felis catus 91.50 0.00e+00 994.00
IUUC-Fal-037592 Ficedula albicollis 68.01 0.00e+00 956.00
IUUC-Gmo-039680 Gadus morhua 44.54 7.00e-152 531.00
IUUC-Gga-041196 Gallus gallus 70.73 0.00e+00 1049.00
IUUC-Gac-042292 Gasterosteus aculeatus 47.45 3.00e-143 502.00
IUUC-Ggo-044671 Gorilla gorilla 91.97 0.00e+00 1432.00
IUUC-Hsa-047020 Homo sapiens 91.85 0.00e+00 1427.00
IUUC-Itr-048800 Ictidomys tridecemlineatus 82.95 0.00e+00 1226.00
IUUC-Lch-050543 Latimeria chalumnae 56.90 0.00e+00 697.00
IUUC-Loc-052338 Lepisosteus oculatus 51.39 0.00e+00 701.00
IUUC-Laf-053707 Loxodonta africana 88.72 0.00e+00 1373.00
IUUC-Mcc-055885 Macaca mulatta 92.48 0.00e+00 1442.00
IUUC-Meu-056573 Macropus eugenii 66.62 0.00e+00 957.00
IUUC-Mga-059346 Meleagris gallopavo 70.85 0.00e+00 992.00
IUUC-Mmr-061612 Microcebus murinus 90.70 0.00e+00 1348.00
IUUC-Mdo-062887 Monodelphis domestica 72.67 0.00e+00 1045.00
IUUC-Mmu-064044 Mus musculus 85.62 0.00e+00 1322.00
IUUC-Mpu-066847 Mustela putorius furo 93.38 0.00e+00 1422.00
IUUC-Mlu-067684 Myotis lucifugus 89.71 0.00e+00 1382.00
IUUC-Nle-070057 Nomascus leucogenys 91.85 0.00e+00 1433.00
IUUC-Opr-070463 Ochotona princeps 81.38 0.00e+00 1208.00
IUUC-Ont-071975 Oreochromis niloticus 46.27 1.00e-151 530.00
IUUC-Oan-073062 Ornithorhynchus anatinus 85.71 5.00e-47 179.00
IUUC-Ocu-074840 Oryctolagus cuniculus 91.08 0.00e+00 1391.00
IUUC-Ola-087088 Oryzias latipes 47.06 7.00e-175 607.00
IUUC-Oga-088472 Otolemur garnettii 90.32 0.00e+00 1380.00
IUUC-Oar-089498 Ovis aries 97.83 0.00e+00 1489.00
IUUC-Ptr-091395 Pan troglodytes 92.10 0.00e+00 1431.00
IUUC-Pan-092462 Papio anubis 92.61 0.00e+00 1443.00
IUUC-Psi-093583 Pelodiscus sinensis 70.58 0.00e+00 891.00
IUUC-Pma-094644 Petromyzon marinus 36.33 7.00e-28 117.00
IUUC-Pfo-096314 Poecilia formosa 47.12 4.00e-169 588.00
IUUC-Pab-098568 Pongo abelii 92.61 0.00e+00 1441.00
IUUC-Pca-100948 Procavia capensis 79.92 0.00e+00 1210.00
IUUC-Pva-102853 Pteropus vampyrus 92.09 0.00e+00 1412.00
IUUC-Rno-105573 Rattus norvegicus 86.11 0.00e+00 1308.00
IUUC-Sha-107495 Sarcophilus harrisii 71.34 0.00e+00 886.00
IUUC-Sar-113545 Sorex araneus 75.26 0.00e+00 1065.00
IUUC-Ssc-115962 Sus scrofa 93.01 0.00e+00 1444.00
IUUC-Tgu-116731 Taeniopygia guttata 68.69 0.00e+00 971.00
IUUC-Tru-117893 Takifugu rubripes 45.44 4.00e-158 551.00
IUUC-Tsy-119644 Tarsius syrichta 81.63 0.00e+00 1212.00
IUUC-Tni-119819 Tetraodon nigroviridis 45.40 1.00e-171 596.00
IUUC-Tbe-127272 Tupaia belangeri 86.69 0.00e+00 1216.00
IUUC-Ttr-128404 Tursiops truncatus 93.10 0.00e+00 1444.00
IUUC-Vpa-130205 Vicugna pacos 91.95 0.00e+00 1420.00
IUUC-Xtr-132613 Xenopus tropicalis 55.14 0.00e+00 740.00
Created Date 25-Jun-2017

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