iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000000476.2	ENSCJAT00000054782.1	ENSCJAP00000048261.1
ENSCJAG00000000476.2	ENSCJAT00000000864.1	ENSCJAP00000000809.1
ENSCJAG00000000476.2	ENSCJAT00000058551.1	ENSCJAP00000047123.1
ENSCJAG00000000476.2	ENSCJAT00000055083.1	ENSCJAP00000047290.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.20e-37	127.7	37	177

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk... 87
           l ke++ele++ p ++++++ d ++l+ ++++++ p++ +Y+gg+F++e e+p+ Y++ PPkvk+ltki+hPn++e+G++Cls+l+   
   Q: 37   LVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVT-PDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLRehs 124
           679********************99*********.**************************************************7778 PP
   S: 88   .eeekWspalsvesvllsiqsllae.pnpesplneeaaellkknreeykkkvr 138
            + + W p+ ++++v+++++sl+++  n+++pln eaae++ +++e++++kv+
   Q: 125  iDGTGWAPTRTLKDVVWGLNSLFTDlLNFDDPLNIEAAEHHLRDKEDFRNKVD 177
           8899*******************8879***********************995 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MLTLASKLKR DDGLKGSRTA ASASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN 60
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTCCGGTC CCGCCGCCGG GAGCCGGTGC GGCTGTGAGG GGCCGCATCA CGCAGCAGCC 60
GCCCCGGCCG GGCATGGTGT TGGGCGCCGG GCCCGCATCA CCTGTCTCGG GGAGCCCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0019788--F:NEDD8 transferase activity
GO:0045116--P:protein neddylation

KEGG

cjc:100409142

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001473	Ailuropoda melanoleuca	96.76	1.00e-93	335.00
IUUC-Apl-003569	Anas platyrhynchos	85.71	3.00e-48	182.00
IUUC-Aca-005152	Anolis carolinensis	90.81	1.00e-98	351.00
IUUC-Ame-011839	Astyanax mexicanus	80.54	2.00e-89	321.00
IUUC-Bta-013524	Bos taurus	96.76	5.00e-94	336.00
IUUC-Cel-018579	Caenorhabditis elegans	58.27	1.00e-35	142.00
IUUC-Cfa-020014	Canis familiaris	96.76	1.00e-93	335.00
IUUC-Cpo-022479	Cavia porcellus	98.92	3.00e-97	347.00
IUUC-Cho-024583	Choloepus hoffmanni	67.03	1.00e-62	232.00
IUUC-Cin-025378	Ciona intestinalis	49.46	7.00e-53	199.00
IUUC-Csv-026195	Ciona savignyi	51.91	4.00e-51	193.00
IUUC-Dre-028671	Danio rerio	82.16	4.00e-91	326.00
IUUC-Dno-029004	Dasypus novemcinctus	98.38	4.00e-108	382.00
IUUC-Dor-030940	Dipodomys ordii	97.84	3.00e-96	343.00
IUUC-Eca-034345	Equus caballus	97.30	5.00e-94	336.00
IUUC-Fca-036125	Felis catus	96.76	2.00e-93	334.00
IUUC-Fal-036808	Ficedula albicollis	92.43	8.00e-102	362.00
IUUC-Gmo-039394	Gadus morhua	90.27	8.00e-61	224.00
IUUC-Gga-041269	Gallus gallus	88.17	1.00e-94	338.00
IUUC-Gac-041480	Gasterosteus aculeatus	82.70	1.00e-89	321.00
IUUC-Ggo-045010	Gorilla gorilla	99.46	8.00e-109	385.00
IUUC-Hsa-046664	Homo sapiens	99.46	8.00e-109	385.00
IUUC-Itr-048522	Ictidomys tridecemlineatus	96.76	7.00e-96	342.00
IUUC-Loc-052137	Lepisosteus oculatus	84.32	2.00e-92	331.00
IUUC-Laf-053694	Loxodonta africana	95.14	3.00e-97	347.00
IUUC-Mcc-055638	Macaca mulatta	99.46	8.00e-109	385.00
IUUC-Meu-056568	Macropus eugenii	77.84	6.00e-81	292.00
IUUC-Mga-059437	Meleagris gallopavo	93.51	4.00e-102	363.00
IUUC-Mmr-060651	Microcebus murinus	94.44	8.00e-91	326.00
IUUC-Mdo-061993	Monodelphis domestica	93.51	1.00e-101	362.00
IUUC-Mmu-064372	Mus musculus	97.30	7.00e-96	342.00
IUUC-Mpu-066423	Mustela putorius furo	96.22	3.00e-93	333.00
IUUC-Mlu-067910	Myotis lucifugus	96.22	2.00e-93	334.00
IUUC-Nle-069032	Nomascus leucogenys	98.92	3.00e-97	347.00
IUUC-Opr-070798	Ochotona princeps	98.92	7.00e-108	382.00
IUUC-Ont-071232	Oreochromis niloticus	83.24	2.00e-90	324.00
IUUC-Oan-072779	Ornithorhynchus anatinus	92.56	5.00e-66	242.00
IUUC-Ocu-074366	Oryctolagus cuniculus	94.59	1.00e-104	371.00
IUUC-Ola-087548	Oryzias latipes	88.14	9.00e-62	228.00
IUUC-Oga-089149	Otolemur garnettii	98.92	2.00e-99	354.00
IUUC-Oar-089662	Ovis aries	96.76	5.00e-94	336.00
IUUC-Ptr-090895	Pan troglodytes	99.46	8.00e-109	385.00
IUUC-Pan-092771	Papio anubis	98.92	2.00e-107	380.00
IUUC-Psi-093582	Pelodiscus sinensis	92.43	2.00e-101	360.00
IUUC-Pma-094321	Petromyzon marinus	84.96	3.00e-67	246.00
IUUC-Pfo-096040	Poecilia formosa	84.32	1.00e-91	328.00
IUUC-Pab-097931	Pongo abelii	99.46	8.00e-109	385.00
IUUC-Pca-100697	Procavia capensis	96.55	3.00e-84	303.00
IUUC-Pva-102609	Pteropus vampyrus	96.22	2.00e-94	337.00
IUUC-Rno-105622	Rattus norvegicus	96.76	7.00e-96	342.00
IUUC-Sha-107614	Sarcophilus harrisii	91.94	4.00e-100	356.00
IUUC-Ssc-115597	Sus scrofa	95.14	1.00e-95	341.00
IUUC-Tgu-117397	Taeniopygia guttata	92.97	3.00e-102	363.00
IUUC-Tru-118496	Takifugu rubripes	81.62	4.00e-88	317.00
IUUC-Tsy-119592	Tarsius syrichta	98.38	4.00e-99	353.00
IUUC-Tni-119759	Tetraodon nigroviridis	81.62	3.00e-88	317.00
IUUC-Tbe-128085	Tupaia belangeri	81.48	9.00e-62	228.00
IUUC-Ttr-129228	Tursiops truncatus	95.68	4.00e-93	333.00
IUUC-Xtr-131773	Xenopus tropicalis	89.78	6.00e-62	229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence