iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068944

Ensembl Protein ID

EAA32101

UniProt Accession

Q1K7R7; Q1K7R7_NEUCR

Genbank Protein ID

EAA32101.1

Protein Name

NEDD8-conjugating enzyme UBC12

Genbank Nucleotide ID

CM002240

Gene Name

NCU03610

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU03610	EAA32101	EAA32101

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-36	124.4	35	167

Active Site

Position(s)	Description	Evidence
113	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesv 101
           R++k+l+el  +  ++++ ++ d +d+ ++ + i+ p++ +Y+gg+F++++++++++P +PPkv++ +ki+hPn++ +GkvCl+il+  e+W+p+l+++ v
   Q: 35   RVQKDLSEL--SLGSTMKTEFPDPDDILNFILYIE-PDEGMYKGGKFSFTFNITPNFPHEPPKVQCREKIYHPNIDLEGKVCLNILR--EDWKPVLNLNAV 130
           889999999..566778889999999*********.**************************************************9..************ PP
   S: 102  llsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++++q l+ epn ++pln+eaae l++nre +k++vr
   Q: 131  IVGLQFLFLEPNASDPLNKEAAEDLRSNREGFKRNVR 167
           ***********************************98 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MLKIWSMKKE QQKAENAAGA ESGGKKKKVT AAQLRVQKDL SELSLGSTMK TEFPDPDDIL 60
NFILYIEPDE GMYKGGKFSF TFNITPNFPH EPPKVQCREK IYHPNIDLEG KVCLNILRED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCCACCCA GGTGTCTAAA CGCCATCAGT TGGGTTTACC ATATCACGTA TCGCGAACCT 60
GGATTTCGCA TCAACACCTG CTACTGTCCT GACAAATCTA GCGCCAACAG GAACTCCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0019788--F:NEDD8 transferase activity
GO:0045116--P:protein neddylation

KEGG

ncr:NCU03610

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000196	Aegilops tauschii	51.43	2.00e-50	189.00
IUUC-Aml-002007	Ailuropoda melanoleuca	59.18	1.00e-51	193.00
IUUC-Atr-003170	Amborella trichopoda	54.95	3.00e-54	202.00
IUUC-Aca-005037	Anolis carolinensis	56.22	4.00e-62	228.00
IUUC-Aly-005638	Arabidopsis lyrata	54.40	6.00e-54	201.00
IUUC-Ath-006876	Arabidopsis thaliana	54.40	6.00e-54	201.00
IUUC-Ago-007910	Ashbya gossypii	46.67	7.00e-39	151.00
IUUC-Acl-008364	Aspergillus clavatus	79.46	2.00e-75	273.00
IUUC-Afl-008463	Aspergillus flavus	77.84	7.00e-75	270.00
IUUC-Afu-008803	Aspergillus fumigatus	78.92	7.00e-75	270.00
IUUC-Ani-009422	Aspergillus nidulans	76.76	4.00e-73	265.00
IUUC-Ang-009728	Aspergillus niger	78.83	2.00e-65	238.00
IUUC-Aor-009962	Aspergillus oryzae	77.84	7.00e-75	270.00
IUUC-Ate-010430	Aspergillus terreus	70.81	1.00e-66	243.00
IUUC-Ame-011382	Astyanax mexicanus	56.76	1.00e-63	233.00
IUUC-Bgr-012306	Blumeria graminis	73.51	5.00e-81	291.00
IUUC-Bta-012818	Bos taurus	56.22	4.00e-62	228.00
IUUC-Bci-013626	Botrytis cinerea	75.14	6.00e-84	301.00
IUUC-Bdi-014528	Brachypodium distachyon	59.35	8.00e-52	194.00
IUUC-Bol-015241	Brassica oleracea	53.59	1.00e-54	203.00
IUUC-Bra-017425	Brassica rapa	55.19	1.00e-55	207.00
IUUC-Cel-018579	Caenorhabditis elegans	38.58	3.00e-18	82.80
IUUC-Cja-019213	Callithrix jacchus	54.74	3.00e-60	222.00
IUUC-Cfa-020242	Canis familiaris	55.61	1.00e-60	223.00
IUUC-Cpo-022405	Cavia porcellus	53.51	2.00e-56	209.00
IUUC-Cre-022865	Chlamydomonas reinhardtii	53.14	6.00e-50	187.00
IUUC-Csa-023269	Chlorocebus sabaeus	56.22	4.00e-62	228.00
IUUC-Cin-025333	Ciona intestinalis	57.84	8.00e-61	224.00
IUUC-Csv-025898	Ciona savignyi	49.54	1.00e-55	207.00
IUUC-Cgl-026477	Colletotrichum gloeosporioides	85.41	2.00e-83	298.00
IUUC-Cne-027097	Cryptococcus neoformans	64.67	2.00e-72	263.00
IUUC-Cme-027287	Cyanidioschyzon merolae	48.24	1.00e-21	94.40
IUUC-Dre-028514	Danio rerio	57.30	3.00e-58	215.00
IUUC-Dno-029678	Dasypus novemcinctus	51.35	3.00e-55	205.00
IUUC-Dor-030940	Dipodomys ordii	42.03	5.00e-25	105.00
IUUC-Dse-031265	Dothistroma septosporum	77.84	3.00e-85	305.00
IUUC-Dme-032076	Drosophila melanogaster	58.89	1.00e-62	230.00
IUUC-Eca-034075	Equus caballus	55.68	5.00e-61	224.00
IUUC-Fca-035654	Felis catus	59.18	1.00e-51	193.00
IUUC-Fal-037283	Ficedula albicollis	59.04	1.00e-26	108.00
IUUC-Fox-037877	Fusarium oxysporum	86.49	1.00e-87	313.00
IUUC-Fso-038428	Fusarium solani	87.03	2.00e-96	342.00
IUUC-Gmo-039402	Gadus morhua	56.22	1.00e-63	233.00
IUUC-Ggr-039731	Gaeumannomyces graminis	84.32	2.00e-82	296.00
IUUC-Gga-041122	Gallus gallus	55.62	1.00e-57	214.00
IUUC-Gac-041480	Gasterosteus aculeatus	35.23	5.00e-27	111.00
IUUC-Gma-043805	Glycine max	55.49	2.00e-54	202.00
IUUC-Ggo-044436	Gorilla gorilla	56.22	4.00e-62	228.00
IUUC-Hsa-046026	Homo sapiens	56.22	4.00e-62	228.00
IUUC-Hvu-047288	Hordeum vulgare	53.80	6.00e-56	207.00
IUUC-Itr-047889	Ictidomys tridecemlineatus	56.22	4.00e-62	228.00
IUUC-Kpa-049315	Komagataella pastoris	53.55	1.00e-51	193.00
IUUC-Lch-050360	Latimeria chalumnae	65.45	2.00e-40	157.00
IUUC-Lpe-050743	Leersia perrieri	55.95	9.00e-54	200.00
IUUC-Loc-052137	Lepisosteus oculatus	35.59	4.00e-24	102.00
IUUC-Lma-053001	Leptosphaeria maculans	76.76	4.00e-75	271.00
IUUC-Laf-053463	Loxodonta africana	59.18	2.00e-51	192.00
IUUC-Mcc-054966	Macaca mulatta	66.67	4.00e-30	120.00
IUUC-Meu-056085	Macropus eugenii	58.22	2.00e-50	189.00
IUUC-Mor-057250	Magnaporthe oryzae	84.32	4.00e-77	278.00
IUUC-Mpo-057481	Magnaporthe poae	84.32	2.00e-77	279.00
IUUC-Mtr-058251	Medicago truncatula	55.80	3.00e-55	206.00
IUUC-Mla-059119	Melampsora laricipopulina	65.41	2.00e-72	262.00
IUUC-Mga-059881	Meleagris gallopavo	62.26	4.00e-38	147.00
IUUC-Mvi-060449	Microbotryum violaceum	63.93	7.00e-64	234.00
IUUC-Mmr-061511	Microcebus murinus	66.67	3.00e-30	120.00
IUUC-Mdo-061993	Monodelphis domestica	38.10	9.00e-26	108.00
IUUC-Mmu-063962	Mus musculus	56.22	4.00e-62	228.00
IUUC-Mac-064967	Musa acuminata	55.80	6.00e-56	208.00
IUUC-Mpu-066423	Mustela putorius furo	41.55	2.00e-25	106.00
IUUC-Mlu-066955	Myotis lucifugus	58.28	4.00e-52	194.00
IUUC-Nfi-068300	Neosartorya fischeri	78.92	7.00e-75	270.00
IUUC-Nle-069051	Nomascus leucogenys	59.18	1.00e-51	193.00
IUUC-Opr-070635	Ochotona princeps	58.90	5.00e-51	191.00
IUUC-Ont-072348	Oreochromis niloticus	56.76	8.00e-64	234.00
IUUC-Ocu-074905	Oryctolagus cuniculus	56.22	4.00e-62	228.00
IUUC-Oba-075825	Oryza barthii	56.00	6.00e-55	204.00
IUUC-Obr-076067	Oryza brachyantha	56.00	5.00e-55	205.00
IUUC-Ogl-077594	Oryza glaberrima	56.00	6.00e-55	204.00
IUUC-Ogu-078073	Oryza glumaepatula	56.00	6.00e-55	204.00
IUUC-Oin-080060	Oryza indica	56.00	5.00e-52	196.00
IUUC-Olo-080314	Oryza longistaminata	56.00	5.00e-55	205.00
IUUC-Ome-081713	Oryza meridionalis	56.00	5.00e-55	205.00
IUUC-Oni-082426	Oryza nivara	56.00	6.00e-55	204.00
IUUC-Opu-083942	Oryza punctata	55.95	5.00e-54	201.00
IUUC-Oru-085104	Oryza rufipogon	56.00	6.00e-55	204.00
IUUC-Osa-086168	Oryza sativa	56.00	6.00e-55	204.00
IUUC-Olu-087854	Ostreococcus lucimarinus	51.61	4.00e-53	198.00
IUUC-Oga-088580	Otolemur garnettii	56.22	4.00e-62	228.00
IUUC-Oar-089623	Ovis aries	55.41	1.00e-45	173.00
IUUC-Ptr-091020	Pan troglodytes	58.90	5.00e-51	191.00
IUUC-Pan-092119	Papio anubis	59.18	1.00e-51	193.00
IUUC-Psi-093494	Pelodiscus sinensis	59.18	1.00e-51	193.00
IUUC-Pma-094321	Petromyzon marinus	43.59	7.00e-22	94.40
IUUC-Pno-094972	Phaeosphaeria nodorum	74.61	4.00e-75	271.00
IUUC-Ppa-095751	Physcomitrella patens	54.05	8.00e-57	210.00
IUUC-Pfo-097205	Poecilia formosa	56.15	6.00e-57	211.00
IUUC-Pab-098434	Pongo abelii	56.22	4.00e-62	228.00
IUUC-Pop-099789	Populus trichocarpa	54.40	1.00e-52	197.00
IUUC-Pca-100300	Procavia capensis	58.90	6.00e-51	190.00
IUUC-Ppe-101216	Prunus persica	53.76	3.00e-47	179.00
IUUC-Pva-102143	Pteropus vampyrus	56.22	4.00e-62	228.00
IUUC-Pgr-103675	Puccinia graminis	65.22	5.00e-71	258.00
IUUC-Ptt-103997	Puccinia triticina	65.76	1.00e-71	259.00
IUUC-Pte-104042	Pyrenophora teres	78.38	3.00e-77	278.00
IUUC-Pyt-104616	Pyrenophora triticirepentis	79.59	9.00e-71	256.00
IUUC-Rno-105107	Rattus norvegicus	56.22	4.00e-62	228.00
IUUC-Sce-106385	Saccharomyces cerevisiae	44.12	4.00e-38	149.00
IUUC-Sha-106899	Sarcophilus harrisii	54.32	2.00e-51	192.00
IUUC-Sja-107789	Schizosaccharomyces japonicus	54.89	9.00e-59	217.00
IUUC-Spo-108143	Schizosaccharomyces pombe	57.30	5.00e-60	221.00
IUUC-Ssl-108427	Sclerotinia sclerotiorum	74.05	1.00e-81	293.00
IUUC-Smo-109440	Selaginella moellendorffii	56.99	4.00e-59	218.00
IUUC-Sit-109702	Setaria italica	60.53	3.00e-52	195.00
IUUC-Sly-111045	Solanum lycopersicum	55.49	3.00e-54	202.00
IUUC-Stu-112381	Solanum tuberosum	53.51	2.00e-55	206.00
IUUC-Sar-113632	Sorex araneus	56.22	3.00e-62	228.00
IUUC-Sbi-114357	Sorghum bicolor	57.42	4.00e-52	195.00
IUUC-Sre-114912	Sporisorium reilianum	65.76	1.00e-67	246.00
IUUC-Ssc-115597	Sus scrofa	42.03	4.00e-25	105.00
IUUC-Tgu-117397	Taeniopygia guttata	36.71	6.00e-25	105.00
IUUC-Tru-118496	Takifugu rubripes	34.66	1.00e-25	107.00
IUUC-Tsy-119639	Tarsius syrichta	48.34	1.00e-39	153.00
IUUC-Tni-119674	Tetraodon nigroviridis	48.11	1.00e-49	187.00
IUUC-Tca-121359	Theobroma cacao	54.95	2.00e-53	199.00
IUUC-Tre-122115	Trichoderma reesei	85.41	3.00e-86	308.00
IUUC-Tvi-122656	Trichoderma virens	84.86	3.00e-85	305.00
IUUC-Tae-125117	Triticum aestivum	53.80	5.00e-56	208.00
IUUC-Tur-126045	Triticum urartu	53.80	5.00e-56	208.00
IUUC-Tme-126950	Tuber melanosporum	74.59	1.00e-71	259.00
IUUC-Tbe-127874	Tupaia belangeri	39.46	1.00e-33	134.00
IUUC-Ttr-128213	Tursiops truncatus	60.25	3.00e-55	205.00
IUUC-Uma-129329	Ustilago maydis	65.22	2.00e-67	245.00
IUUC-Vda-129754	Verticillium dahliae	84.32	6.00e-82	294.00
IUUC-Vvi-131182	Vitis vinifera	54.40	8.00e-53	197.00
IUUC-Xtr-132742	Xenopus tropicalis	56.76	2.00e-62	229.00
IUUC-Xma-133558	Xiphophorus maculatus	56.76	2.00e-58	216.00
IUUC-Yli-134467	Yarrowia lipolytica	67.93	1.00e-74	270.00
IUUC-Zma-135527	Zea mays	58.06	3.00e-52	195.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence