iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132913

UUCD1 version

UUC-XeT-00923

Ensembl Protein ID

ENSXETP00000004775.3

UniProt Accession

Q5FW06; DCA10_XENTR

Genbank Protein ID

CAJ81491.1; AAH89677.1

Protein Name

DDB1- and CUL4-associated factor 10; WD repeat-containing protein 32

Genbank Nucleotide ID

CR762027; BC089677

Gene Name

dcaf10; wdr32; TEgg067n05.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000002243.3	ENSXETT00000004775.3	ENSXETP00000004775.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-17	61.5	109	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrt 32
           H+d v+ ++f ++++++++sdD ti +WDlr+
   Q: 109  HEDCVNNIRFlDNRMFATCSDDTTIALWDLRK 140
           9*********766****************987 PP

Organism

Xenopus tropicalis

Functional Description
(View)

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Protein Sequence
(Fasta)

MEGGTNDGAA VPGNGAGTAG SIFWWLKNRC LGRGLCVDPA RDNFRTMTSL YSSIHPADSV 60
NLSTRTHGAV FNLEYSPDGS VLTVACEQTE VLLFDPVSSK HIKTLSEAHE DCVNNIRFLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGAGCGG GCCGGCAGAA GCGGAGGCTT ACATTTAAAC AGTGATGCGG GACATTTAAA 60
CCTCGGTCTG GCTCTGCGGG CTGTGTTATG AAAATAGAGA CTCTCCCGCG AATAGCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

xtr:548459

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002004	Ailuropoda melanoleuca	89.23	0.00e+00	724.00
IUUC-Apl-003942	Anas platyrhynchos	87.69	0.00e+00	685.00
IUUC-Aca-005259	Anolis carolinensis	85.62	0.00e+00	748.00
IUUC-Ame-010936	Astyanax mexicanus	77.51	0.00e+00	706.00
IUUC-Bta-012820	Bos taurus	88.06	0.00e+00	763.00
IUUC-Cja-019380	Callithrix jacchus	86.26	0.00e+00	758.00
IUUC-Cfa-021136	Canis familiaris	89.20	0.00e+00	757.00
IUUC-Cpo-021784	Cavia porcellus	87.84	0.00e+00	759.00
IUUC-Csa-024250	Chlorocebus sabaeus	86.49	0.00e+00	760.00
IUUC-Cin-025712	Ciona intestinalis	43.11	1.00e-36	146.00
IUUC-Csv-025985	Ciona savignyi	38.01	4.00e-34	137.00
IUUC-Dre-027652	Danio rerio	79.45	0.00e+00	694.00
IUUC-Dno-030060	Dasypus novemcinctus	90.26	0.00e+00	685.00
IUUC-Dme-031950	Drosophila melanogaster	36.88	4.00e-48	186.00
IUUC-Ete-032379	Echinops telfairi	76.05	1.00e-158	551.00
IUUC-Eca-034313	Equus caballus	89.95	0.00e+00	686.00
IUUC-Fca-036273	Felis catus	90.32	0.00e+00	764.00
IUUC-Fal-037620	Ficedula albicollis	88.34	0.00e+00	683.00
IUUC-Gmo-038647	Gadus morhua	78.63	3.00e-166	577.00
IUUC-Gga-040735	Gallus gallus	90.24	0.00e+00	687.00
IUUC-Gac-041703	Gasterosteus aculeatus	77.56	0.00e+00	702.00
IUUC-Ggo-045268	Gorilla gorilla	87.82	0.00e+00	756.00
IUUC-Hsa-046127	Homo sapiens	87.82	0.00e+00	758.00
IUUC-Itr-048027	Ictidomys tridecemlineatus	86.59	9.00e-170	588.00
IUUC-Lch-050191	Latimeria chalumnae	87.36	0.00e+00	781.00
IUUC-Loc-052006	Lepisosteus oculatus	81.06	0.00e+00	749.00
IUUC-Laf-053546	Loxodonta africana	88.71	0.00e+00	785.00
IUUC-Mcc-055391	Macaca mulatta	88.68	0.00e+00	657.00
IUUC-Meu-056599	Macropus eugenii	89.58	3.00e-101	362.00
IUUC-Mga-059625	Meleagris gallopavo	88.21	2.00e-102	364.00
IUUC-Mmr-061695	Microcebus murinus	87.84	0.00e+00	779.00
IUUC-Mdo-062960	Monodelphis domestica	90.41	0.00e+00	791.00
IUUC-Mmu-063543	Mus musculus	89.66	0.00e+00	779.00
IUUC-Mpu-066132	Mustela putorius furo	88.74	0.00e+00	752.00
IUUC-Mlu-067070	Myotis lucifugus	87.63	0.00e+00	654.00
IUUC-Nle-069325	Nomascus leucogenys	88.68	0.00e+00	657.00
IUUC-Opr-070537	Ochotona princeps	71.58	5.00e-148	517.00
IUUC-Ont-072184	Oreochromis niloticus	79.59	0.00e+00	714.00
IUUC-Oan-072696	Ornithorhynchus anatinus	87.75	0.00e+00	692.00
IUUC-Ocu-074877	Oryctolagus cuniculus	88.29	0.00e+00	791.00
IUUC-Ola-086632	Oryzias latipes	80.78	0.00e+00	633.00
IUUC-Oga-088050	Otolemur garnettii	86.91	0.00e+00	756.00
IUUC-Oar-089358	Ovis aries	80.36	0.00e+00	686.00
IUUC-Ptr-091497	Pan troglodytes	87.82	0.00e+00	758.00
IUUC-Pan-092813	Papio anubis	87.61	0.00e+00	775.00
IUUC-Psi-093404	Pelodiscus sinensis	91.56	0.00e+00	695.00
IUUC-Pfo-097103	Poecilia formosa	79.82	0.00e+00	714.00
IUUC-Pab-098099	Pongo abelii	86.22	0.00e+00	763.00
IUUC-Pca-100777	Procavia capensis	61.90	9.00e-81	294.00
IUUC-Pva-102912	Pteropus vampyrus	87.39	0.00e+00	783.00
IUUC-Rno-104970	Rattus norvegicus	87.39	0.00e+00	775.00
IUUC-Sha-106821	Sarcophilus harrisii	87.56	0.00e+00	782.00
IUUC-Sar-113508	Sorex araneus	92.27	1.00e-99	356.00
IUUC-Ssc-116373	Sus scrofa	87.28	0.00e+00	754.00
IUUC-Tgu-117223	Taeniopygia guttata	88.25	0.00e+00	679.00
IUUC-Tru-118116	Takifugu rubripes	76.36	8.00e-95	340.00
IUUC-Tsy-119525	Tarsius syrichta	88.16	0.00e+00	654.00
IUUC-Tni-119799	Tetraodon nigroviridis	76.34	0.00e+00	710.00
IUUC-Ttr-128611	Tursiops truncatus	84.46	0.00e+00	722.00
IUUC-Vpa-130806	Vicugna pacos	60.95	2.00e-108	386.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence