iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-009045

Ensembl Protein ID

CADAFUAP00007578

UniProt Accession

Q4WT34; PRP46_ASPFU

Genbank Protein ID

EAL90398.1

Protein Name

Pre-mRNA-splicing factor prp46; Pre-mRNA-processing protein 46

Genbank Nucleotide ID

AAHF01000004

Gene Name

AFUA_1G10710; prp46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00007578	CADAFUAT00007578	CADAFUAP00007578

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-43	142.6	142	176
UBD/Beta-Prp	6.80e-62	208.3	145	389

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH ++v++la  ++   ++sG++D tik+W+l tg
   Q: 142  GHLGWVRSLAVePNnEWFASGAGDRTIKIWNLATG 176
           8***********66699***************998 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           + ++++++ p+++++a+g  d+tik+w++ tg l  +l gh ++v+ +  sp+ ++l +++eD+++k wdl+t+k +++++gh + v++l+++
   Q: 145  GWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALH 237
           45778999************************************************************************************* PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelv 196
           p  d lv+G++d ++rvwd++t++ ++ +lsgh+g+v  ++ ++ +  +++GslD tvrlWdl+ gk +  lt  h++ v+ l++++  + ++
   Q: 238  PRLDLLVTGGRDGVARVWDMRTRSNIH-VLSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAAGKTMGVLTH-HKKGVRNLAIHPREFTFA 328
           ***************************.*********************************************9.************999999 PP
   S: 197  sgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
           s+s+ g++k w + +g+ ++ ++gh++ ++s+++  +d+ l sg++ gs  +Wd ++g   ++
   Q: 329  SAST-GSIKQWKCPEGDFMQNFEGHNAVINSLAVN-EDNVLFSGGDNGSMCFWDWKTGYKFQS 389
           9987.89****************************.9*******************9976665 PP

Organism

Aspergillus fumigatus

Functional Description
(View)

Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.

Protein Sequence
(Fasta)

MDVFPSTTPD EAVRKSAKRT AELFGSEYLL VTPSVADGSI GLSYRKKAEY SDVKELPPAL 60
AEKQAKAAAA GRAKRPKIQP QTKPQADGSG ASMSLVKRAA GPAAGGVGGE GQPKSLIQRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGTCT TCCCTTCTAC CACACCGGAC GAAGCCGTCC GCAAATCCGC GAAGCGAACC 60
GCTGAACTTT TCGGCTCCGA ATACCTCCTG GTCACACCTA GCGTCGCCGA TGGATCGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005681--C:spliceosomal complex
GO:0006397--P:mRNA processing
GO:0008380--P:RNA splicing

KEGG

afm:AFUA_1G10710

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	55.77	1.00e-121	428.00
IUUC-Aml-001605	Ailuropoda melanoleuca	64.94	3.00e-136	476.00
IUUC-Atr-002757	Amborella trichopoda	61.20	3.00e-123	433.00
IUUC-Apl-003198	Anas platyrhynchos	65.55	7.00e-137	478.00
IUUC-Aca-004683	Anolis carolinensis	65.55	2.00e-137	480.00
IUUC-Aly-005775	Arabidopsis lyrata	55.15	4.00e-126	442.00
IUUC-Ath-007460	Arabidopsis thaliana	60.24	4.00e-125	439.00
IUUC-Ago-007884	Ashbya gossypii	54.97	3.00e-118	416.00
IUUC-Acl-008153	Aspergillus clavatus	93.82	0.00e+00	812.00
IUUC-Afl-008384	Aspergillus flavus	91.61	0.00e+00	795.00
IUUC-Ani-009229	Aspergillus nidulans	83.08	0.00e+00	725.00
IUUC-Ang-009812	Aspergillus niger	92.74	9.00e-175	603.00
IUUC-Aor-010059	Aspergillus oryzae	91.61	0.00e+00	795.00
IUUC-Ate-010351	Aspergillus terreus	87.64	0.00e+00	790.00
IUUC-Ame-011613	Astyanax mexicanus	45.53	5.00e-77	280.00
IUUC-Bgr-012042	Blumeria graminis	84.08	8.00e-178	614.00
IUUC-Bta-012406	Bos taurus	64.94	5.00e-136	476.00
IUUC-Bci-013760	Botrytis cinerea	67.81	2.00e-173	600.00
IUUC-Bdi-014776	Brachypodium distachyon	59.64	5.00e-124	436.00
IUUC-Bol-016189	Brassica oleracea	60.24	3.00e-125	439.00
IUUC-Bra-018044	Brassica rapa	60.24	7.00e-125	439.00
IUUC-Cel-018651	Caenorhabditis elegans	64.95	4.00e-138	483.00
IUUC-Cja-019974	Callithrix jacchus	64.63	5.00e-136	475.00
IUUC-Cfa-021085	Canis familiaris	64.94	4.00e-136	476.00
IUUC-Cpo-021458	Cavia porcellus	64.63	5.00e-136	475.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	62.88	3.00e-127	446.00
IUUC-Csa-023883	Chlorocebus sabaeus	64.63	5.00e-136	475.00
IUUC-Cho-024623	Choloepus hoffmanni	64.60	2.00e-132	464.00
IUUC-Cin-025190	Ciona intestinalis	64.20	1.00e-137	481.00
IUUC-Csv-026367	Ciona savignyi	63.91	5.00e-137	479.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	71.94	0.00e+00	627.00
IUUC-Cne-027069	Cryptococcus neoformans	57.08	6.00e-142	495.00
IUUC-Cme-027233	Cyanidioschyzon merolae	32.22	3.00e-38	150.00
IUUC-Dre-028260	Danio rerio	66.28	1.00e-141	494.00
IUUC-Dno-029112	Dasypus novemcinctus	64.63	6.00e-136	475.00
IUUC-Dor-031118	Dipodomys ordii	64.33	2.00e-135	473.00
IUUC-Dse-031493	Dothistroma septosporum	63.90	8.00e-166	575.00
IUUC-Dme-032138	Drosophila melanogaster	66.25	5.00e-139	485.00
IUUC-Ete-032411	Echinops telfairi	55.36	2.00e-111	394.00
IUUC-Eca-033521	Equus caballus	64.33	2.00e-135	474.00
IUUC-Eeu-035249	Erinaceus europaeus	55.18	4.00e-106	376.00
IUUC-Fca-036358	Felis catus	64.33	4.00e-135	473.00
IUUC-Fal-036933	Ficedula albicollis	65.55	4.00e-137	479.00
IUUC-Fox-037713	Fusarium oxysporum	72.38	6.00e-179	618.00
IUUC-Fso-038380	Fusarium solani	83.38	2.00e-177	613.00
IUUC-Gmo-039133	Gadus morhua	67.07	5.00e-139	486.00
IUUC-Ggr-039915	Gaeumannomyces graminis	79.53	1.00e-163	567.00
IUUC-Gga-041176	Gallus gallus	64.33	7.00e-136	475.00
IUUC-Gac-042344	Gasterosteus aculeatus	67.07	1.00e-139	488.00
IUUC-Gma-043328	Glycine max	61.59	2.00e-125	441.00
IUUC-Ggo-044478	Gorilla gorilla	64.63	7.00e-136	475.00
IUUC-Hsa-046037	Homo sapiens	64.63	7.00e-136	475.00
IUUC-Hvu-047349	Hordeum vulgare	60.54	2.00e-125	441.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	64.63	6.00e-136	475.00
IUUC-Kpa-049343	Komagataella pastoris	57.62	1.00e-122	431.00
IUUC-Lch-049830	Latimeria chalumnae	64.94	2.00e-137	480.00
IUUC-Lpe-051442	Leersia perrieri	49.78	7.00e-126	442.00
IUUC-Loc-051794	Lepisosteus oculatus	68.61	3.00e-134	469.00
IUUC-Lma-053137	Leptosphaeria maculans	56.35	7.00e-157	545.00
IUUC-Laf-053471	Loxodonta africana	64.63	4.00e-136	476.00
IUUC-Mcc-055627	Macaca mulatta	64.63	7.00e-136	475.00
IUUC-Meu-056148	Macropus eugenii	62.80	1.00e-131	461.00
IUUC-Mor-056960	Magnaporthe oryzae	79.82	9.00e-172	594.00
IUUC-Mtr-057816	Medicago truncatula	60.98	2.00e-125	440.00
IUUC-Mla-059031	Melampsora laricipopulina	65.35	5.00e-140	488.00
IUUC-Mga-059337	Meleagris gallopavo	64.33	1.00e-135	474.00
IUUC-Mvi-060217	Microbotryum violaceum	71.38	3.00e-144	503.00
IUUC-Mmr-061018	Microcebus murinus	64.63	1.00e-135	474.00
IUUC-Mdo-062863	Monodelphis domestica	65.23	2.00e-135	474.00
IUUC-Mmu-063988	Mus musculus	64.94	3.00e-135	473.00
IUUC-Mac-064459	Musa acuminata	60.57	6.00e-120	422.00
IUUC-Mpu-066559	Mustela putorius furo	64.94	6.00e-136	475.00
IUUC-Mlu-067361	Myotis lucifugus	64.63	1.00e-135	474.00
IUUC-Nfi-068492	Neosartorya fischeri	99.12	0.00e+00	839.00
IUUC-Ncr-068808	Neurospora crassa	80.70	2.00e-175	607.00
IUUC-Nle-069875	Nomascus leucogenys	64.63	6.00e-136	475.00
IUUC-Opr-070462	Ochotona princeps	64.29	7.00e-108	382.00
IUUC-Ont-071365	Oreochromis niloticus	67.38	8.00e-140	488.00
IUUC-Oan-072708	Ornithorhynchus anatinus	64.94	3.00e-136	476.00
IUUC-Ocu-074594	Oryctolagus cuniculus	64.63	1.00e-135	474.00
IUUC-Oba-075570	Oryza barthii	50.45	7.00e-127	445.00
IUUC-Obr-076366	Oryza brachyantha	63.27	1.00e-89	320.00
IUUC-Ogl-077153	Oryza glaberrima	50.45	4.00e-126	442.00
IUUC-Ogu-078540	Oryza glumaepatula	50.67	3.00e-127	446.00
IUUC-Oin-079612	Oryza indica	50.11	3.00e-125	439.00
IUUC-Olo-081077	Oryza longistaminata	50.11	3.00e-125	439.00
IUUC-Ome-081236	Oryza meridionalis	49.89	5.00e-125	439.00
IUUC-Oni-082499	Oryza nivara	50.67	3.00e-127	446.00
IUUC-Opu-083499	Oryza punctata	50.11	3.00e-125	439.00
IUUC-Oru-084276	Oryza rufipogon	50.67	3.00e-127	446.00
IUUC-Osa-085849	Oryza sativa	50.67	3.00e-127	446.00
IUUC-Ola-086655	Oryzias latipes	66.77	1.00e-139	488.00
IUUC-Olu-087637	Ostreococcus lucimarinus	62.69	2.00e-128	450.00
IUUC-Oga-087934	Otolemur garnettii	64.63	5.00e-136	475.00
IUUC-Oar-090185	Ovis aries	64.94	5.00e-136	476.00
IUUC-Ptr-091198	Pan troglodytes	64.63	6.00e-136	475.00
IUUC-Pan-092622	Papio anubis	64.63	5.00e-136	475.00
IUUC-Psi-093320	Pelodiscus sinensis	64.94	6.00e-136	475.00
IUUC-Pma-094638	Petromyzon marinus	66.37	5.00e-140	489.00
IUUC-Pno-094826	Phaeosphaeria nodorum	63.05	2.00e-135	474.00
IUUC-Ppa-095576	Physcomitrella patens	62.78	2.00e-123	434.00
IUUC-Pfo-096894	Poecilia formosa	67.07	9.00e-140	488.00
IUUC-Pab-098020	Pongo abelii	64.63	5.00e-136	476.00
IUUC-Pop-099180	Populus trichocarpa	59.62	9.00e-119	418.00
IUUC-Pca-100909	Procavia capensis	67.06	2.00e-107	380.00
IUUC-Ppe-101346	Prunus persica	59.34	3.00e-124	436.00
IUUC-Pva-102167	Pteropus vampyrus	55.49	8.00e-111	392.00
IUUC-Pgr-103516	Puccinia graminis	69.91	2.00e-140	490.00
IUUC-Ptt-103738	Puccinia triticina	69.91	2.00e-139	486.00
IUUC-Pte-104352	Pyrenophora teres	57.26	4.00e-162	562.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	56.82	8.00e-162	561.00
IUUC-Rno-105291	Rattus norvegicus	64.63	2.00e-135	473.00
IUUC-Sce-106204	Saccharomyces cerevisiae	56.01	4.00e-121	426.00
IUUC-Sha-106943	Sarcophilus harrisii	63.80	3.00e-132	463.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	73.50	3.00e-145	506.00
IUUC-Spo-108049	Schizosaccharomyces pombe	71.76	8.00e-150	521.00
IUUC-Smo-109043	Selaginella moellendorffii	59.47	2.00e-125	440.00
IUUC-Sit-110431	Setaria italica	59.94	1.00e-124	437.00
IUUC-Sly-111391	Solanum lycopersicum	60.94	8.00e-120	422.00
IUUC-Stu-112364	Solanum tuberosum	55.45	3.00e-95	339.00
IUUC-Sar-113450	Sorex araneus	64.33	1.00e-134	471.00
IUUC-Sbi-113829	Sorghum bicolor	49.78	2.00e-126	444.00
IUUC-Sre-115153	Sporisorium reilianum	65.62	3.00e-129	453.00
IUUC-Ssc-116274	Sus scrofa	64.63	8.00e-136	475.00
IUUC-Tgu-117417	Taeniopygia guttata	65.55	5.00e-137	479.00
IUUC-Tru-117615	Takifugu rubripes	65.55	2.00e-132	463.00
IUUC-Tsy-119480	Tarsius syrichta	64.63	7.00e-136	475.00
IUUC-Tni-119847	Tetraodon nigroviridis	66.77	2.00e-139	487.00
IUUC-Tca-121287	Theobroma cacao	54.21	1.00e-122	431.00
IUUC-Tre-122010	Trichoderma reesei	84.04	4.00e-178	615.00
IUUC-Tvi-122475	Trichoderma virens	68.82	1.00e-177	614.00
IUUC-Tae-124243	Triticum aestivum	60.54	3.00e-125	440.00
IUUC-Tur-126116	Triticum urartu	50.00	1.00e-92	331.00
IUUC-Tme-126992	Tuber melanosporum	76.76	4.00e-166	576.00
IUUC-Tbe-127803	Tupaia belangeri	68.03	1.00e-104	371.00
IUUC-Ttr-128933	Tursiops truncatus	64.63	8.00e-136	475.00
IUUC-Uma-129447	Ustilago maydis	63.95	5.00e-128	449.00
IUUC-Vda-129780	Verticillium dahliae	82.20	9.00e-177	611.00
IUUC-Vpa-130557	Vicugna pacos	43.78	8.00e-48	182.00
IUUC-Vvi-130918	Vitis vinifera	59.62	1.00e-119	421.00
IUUC-Xtr-132409	Xenopus tropicalis	64.94	1.00e-135	474.00
IUUC-Xma-133420	Xiphophorus maculatus	67.07	1.00e-139	488.00
IUUC-Yli-134362	Yarrowia lipolytica	63.28	1.00e-133	467.00
IUUC-Zma-135804	Zea mays	58.46	2.00e-121	427.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence