iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007884

Ensembl Protein ID

AAS51363

UniProt Accession

Q75BY3; PRP46_ASHGO

Genbank Protein ID

AAS51363.2

Protein Name

Pre-mRNA-splicing factor PRP46; Pre-mRNA-processing protein 46

Genbank Nucleotide ID

AE016816

Gene Name

PRP46; ACR137W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_ACR137W	AAS51363	AAS51363

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-35	118.0	111	149
UBD/Beta-Prp	1.70e-57	192.8	112	401

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvll 36
           gHt++v+c++    ++  +++Gs+D ti+vWDl tg+l 
   Q: 111  GHTGWVRCVCVdpvDNAWFATGSNDSTIRVWDLATGKLK 149
           8********9999544779****************9875 PP

UBD/Beta-Prp

   S: 9    hksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
           h++ ++cv++   d+ ++atgs d+ti+vwd+ tgkl  +l+gh  +v+++++s + +++ ++s+D+++k wdl+ ++ v+ ++g  + v s++++ps d 
   Q: 112  HTGWVRCVCVdPVDNAWFATGSNDSTIRVWDLATGKLKVTLQGHIMTVRDICISARHPYMFSASQDKLVKCWDLERNTVVRDFHGTLSGVHSVDLHPSLDL 212
           7788999***777899************************************************************************************* PP
   S: 109  lvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           +vs+++d+++rvwd+++++c+  tl+gh+g +n v+  p +  +vs+s+D tv+lWdl  gk ++tlt  h++ v+ l+f+++ ++++s+ +d +++ w l
   Q: 213  IVSAGRDSVVRVWDIRSRSCVL-TLAGHRGPINKVRCLPVDPQIVSCSTDATVKLWDLVAGKPMKTLTH-HKRNVRDLAFNPTEFSFASACTD-DIRSWKL 310
           **********************.*********************************************9.**************999997666.8****** PP
   S: 210  qtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn.......ssvisvavlsfgdnvlvlgsedskvniwk 293
             g+ +  +n     +    ++++d  l  g++ g ++++d+++g   ++l+ ++       ++ +  ++++ ++  l++++ d++++iwk
   Q: 311  VDGQLLTNFNSEALGIVNTLACNQDGVLFAGGDTGELSFFDYKTGHKFQKLETTAmpgslesEKGVLASTFDRTGLRLLTCERDKSIKIWK 401
           ***********999999999999*************************************99888888888999****************8 PP

Organism

Ashbya gossypii

Functional Description
(View)

Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.

Protein Sequence
(Fasta)

MNEHSDDVYV RARLRNQFGY MTWVPEYVED RISSKKGILQ RYEDYQQKQA KAQEVKTDSL 60
VKYEGAKDVP RNLLRIYRGE ADTSALARYE EVVSQKPQWH APWKLTRVIN GHTGWVRCVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATGAGC ACAGCGATGA TGTATATGTA CGTGCGAGGC TGCGCAACCA GTTTGGTTAT 60
ATGACATGGG TACCAGAATA TGTCGAAGAC AGAATCAGTA GCAAGAAAGG CATACTGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0071014--C:post-mRNA release spliceosomal complex
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0045292--P:mRNA cis splicing, via spliceosome
GO:0000398--P:mRNA splicing, via spliceosome

KEGG

ago:AGOS_ACR137W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	48.90	1.00e-99	355.00
IUUC-Aml-001605	Ailuropoda melanoleuca	49.71	1.00e-107	381.00
IUUC-Atr-002757	Amborella trichopoda	54.25	2.00e-102	363.00
IUUC-Apl-003198	Anas platyrhynchos	49.71	3.00e-107	380.00
IUUC-Aca-004683	Anolis carolinensis	48.85	7.00e-107	378.00
IUUC-Aly-005775	Arabidopsis lyrata	51.16	5.00e-105	372.00
IUUC-Ath-007460	Arabidopsis thaliana	50.87	2.00e-104	370.00
IUUC-Acl-008153	Aspergillus clavatus	56.43	5.00e-114	402.00
IUUC-Afl-008384	Aspergillus flavus	54.29	2.00e-115	407.00
IUUC-Afu-009045	Aspergillus fumigatus	54.97	2.00e-112	397.00
IUUC-Ani-009229	Aspergillus nidulans	55.69	2.00e-114	403.00
IUUC-Ang-009812	Aspergillus niger	57.68	1.00e-107	380.00
IUUC-Aor-010059	Aspergillus oryzae	54.29	2.00e-115	407.00
IUUC-Ate-010351	Aspergillus terreus	56.73	1.00e-120	424.00
IUUC-Ame-011613	Astyanax mexicanus	33.61	1.00e-53	201.00
IUUC-Bgr-012042	Blumeria graminis	47.74	8.00e-121	424.00
IUUC-Bta-012406	Bos taurus	47.96	3.00e-107	380.00
IUUC-Bci-013760	Botrytis cinerea	52.20	4.00e-115	405.00
IUUC-Bdi-014776	Brachypodium distachyon	52.12	4.00e-102	362.00
IUUC-Bol-016189	Brassica oleracea	51.16	1.00e-104	371.00
IUUC-Bra-018044	Brassica rapa	51.16	2.00e-104	370.00
IUUC-Cel-018651	Caenorhabditis elegans	50.57	3.00e-106	376.00
IUUC-Cja-019974	Callithrix jacchus	47.27	1.00e-108	384.00
IUUC-Cfa-021085	Canis familiaris	49.71	1.00e-107	380.00
IUUC-Cpo-021458	Cavia porcellus	47.93	2.00e-107	380.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	52.19	4.00e-110	389.00
IUUC-Csa-023883	Chlorocebus sabaeus	46.49	3.00e-108	383.00
IUUC-Cho-024623	Choloepus hoffmanni	48.98	2.00e-102	363.00
IUUC-Cin-025190	Ciona intestinalis	48.69	4.00e-106	375.00
IUUC-Csv-026367	Ciona savignyi	45.48	2.00e-106	377.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	55.69	9.00e-120	421.00
IUUC-Cne-027069	Cryptococcus neoformans	53.12	6.00e-104	369.00
IUUC-Cme-027233	Cyanidioschyzon merolae	28.74	5.00e-27	112.00
IUUC-Dre-028260	Danio rerio	48.46	2.00e-105	374.00
IUUC-Dno-029112	Dasypus novemcinctus	49.43	2.00e-107	380.00
IUUC-Dor-031118	Dipodomys ordii	48.45	5.00e-107	378.00
IUUC-Dse-031493	Dothistroma septosporum	52.19	9.00e-108	381.00
IUUC-Dme-032138	Drosophila melanogaster	48.77	8.00e-103	365.00
IUUC-Ete-032411	Echinops telfairi	43.06	6.00e-87	312.00
IUUC-Eca-033521	Equus caballus	49.14	5.00e-107	379.00
IUUC-Eeu-035249	Erinaceus europaeus	42.82	8.00e-83	298.00
IUUC-Fca-036358	Felis catus	49.71	8.00e-108	381.00
IUUC-Fal-036933	Ficedula albicollis	49.71	2.00e-107	380.00
IUUC-Fox-037713	Fusarium oxysporum	46.39	3.00e-120	422.00
IUUC-Fso-038380	Fusarium solani	54.85	7.00e-116	408.00
IUUC-Gmo-039133	Gadus morhua	48.73	2.00e-105	374.00
IUUC-Ggr-039915	Gaeumannomyces graminis	52.63	5.00e-107	379.00
IUUC-Gga-041176	Gallus gallus	49.43	8.00e-107	378.00
IUUC-Gac-042344	Gasterosteus aculeatus	50.00	7.00e-106	375.00
IUUC-Gma-043328	Glycine max	49.46	3.00e-104	369.00
IUUC-Ggo-044478	Gorilla gorilla	46.49	2.00e-108	383.00
IUUC-Hsa-046037	Homo sapiens	46.49	2.00e-108	384.00
IUUC-Hvu-047349	Hordeum vulgare	53.33	5.00e-104	369.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	47.43	3.00e-107	379.00
IUUC-Kpa-049343	Komagataella pastoris	61.96	3.00e-125	439.00
IUUC-Lch-049830	Latimeria chalumnae	51.36	6.00e-108	382.00
IUUC-Lpe-051442	Leersia perrieri	48.28	2.00e-103	367.00
IUUC-Loc-051794	Lepisosteus oculatus	50.46	4.00e-101	359.00
IUUC-Lma-053137	Leptosphaeria maculans	48.76	5.00e-113	399.00
IUUC-Laf-053471	Loxodonta africana	49.42	9.00e-107	378.00
IUUC-Mcc-055627	Macaca mulatta	46.49	3.00e-108	383.00
IUUC-Meu-056148	Macropus eugenii	47.41	3.00e-102	363.00
IUUC-Mor-056960	Magnaporthe oryzae	53.96	8.00e-115	404.00
IUUC-Mtr-057816	Medicago truncatula	51.60	3.00e-104	369.00
IUUC-Mla-059031	Melampsora laricipopulina	49.54	2.00e-97	347.00
IUUC-Mga-059337	Meleagris gallopavo	49.43	9.00e-107	378.00
IUUC-Mvi-060217	Microbotryum violaceum	51.39	1.00e-103	367.00
IUUC-Mmr-061018	Microcebus murinus	47.43	3.00e-107	379.00
IUUC-Mdo-062863	Monodelphis domestica	50.76	1.00e-105	374.00
IUUC-Mmu-063988	Mus musculus	49.71	4.00e-107	379.00
IUUC-Mac-064459	Musa acuminata	50.47	3.00e-98	350.00
IUUC-Mpu-066559	Mustela putorius furo	49.71	1.00e-107	380.00
IUUC-Mlu-067361	Myotis lucifugus	49.71	9.00e-108	381.00
IUUC-Nfi-068492	Neosartorya fischeri	55.26	1.00e-112	397.00
IUUC-Ncr-068808	Neurospora crassa	52.15	5.00e-115	405.00
IUUC-Nle-069875	Nomascus leucogenys	46.49	2.00e-108	384.00
IUUC-Opr-070462	Ochotona princeps	47.94	4.00e-81	293.00
IUUC-Ont-071365	Oreochromis niloticus	49.71	4.00e-105	372.00
IUUC-Oan-072708	Ornithorhynchus anatinus	49.43	4.00e-107	379.00
IUUC-Ocu-074594	Oryctolagus cuniculus	48.45	2.00e-107	380.00
IUUC-Oba-075570	Oryza barthii	48.28	2.00e-103	366.00
IUUC-Obr-076366	Oryza brachyantha	53.59	6.00e-74	268.00
IUUC-Ogl-077153	Oryza glaberrima	47.48	7.00e-103	365.00
IUUC-Ogu-078540	Oryza glumaepatula	48.28	3.00e-103	366.00
IUUC-Oin-079612	Oryza indica	47.64	2.00e-101	360.00
IUUC-Olo-081077	Oryza longistaminata	47.64	2.00e-101	360.00
IUUC-Ome-081236	Oryza meridionalis	52.24	2.00e-101	360.00
IUUC-Oni-082499	Oryza nivara	48.28	3.00e-103	366.00
IUUC-Opu-083499	Oryza punctata	51.94	3.00e-101	359.00
IUUC-Oru-084276	Oryza rufipogon	48.28	3.00e-103	366.00
IUUC-Osa-085849	Oryza sativa	48.28	3.00e-103	366.00
IUUC-Ola-086655	Oryzias latipes	44.86	1.00e-104	371.00
IUUC-Olu-087637	Ostreococcus lucimarinus	47.79	9.00e-104	367.00
IUUC-Oga-087934	Otolemur garnettii	47.31	4.00e-107	379.00
IUUC-Oar-090185	Ovis aries	47.52	2.00e-108	384.00
IUUC-Ptr-091198	Pan troglodytes	46.49	2.00e-108	384.00
IUUC-Pan-092622	Papio anubis	46.49	3.00e-108	383.00
IUUC-Psi-093320	Pelodiscus sinensis	49.43	8.00e-107	378.00
IUUC-Pma-094638	Petromyzon marinus	48.85	4.00e-104	369.00
IUUC-Pno-094826	Phaeosphaeria nodorum	42.14	1.00e-94	338.00
IUUC-Ppa-095576	Physcomitrella patens	52.04	2.00e-99	354.00
IUUC-Pfo-096894	Poecilia formosa	49.43	3.00e-105	373.00
IUUC-Pab-098020	Pongo abelii	46.49	2.00e-108	384.00
IUUC-Pop-099180	Populus trichocarpa	52.04	9.00e-99	351.00
IUUC-Pca-100909	Procavia capensis	50.36	3.00e-84	303.00
IUUC-Ppe-101346	Prunus persica	50.44	7.00e-103	365.00
IUUC-Pva-102167	Pteropus vampyrus	43.68	1.00e-87	314.00
IUUC-Pgr-103516	Puccinia graminis	49.23	3.00e-97	346.00
IUUC-Ptt-103738	Puccinia triticina	49.85	1.00e-96	344.00
IUUC-Pte-104352	Pyrenophora teres	46.86	3.00e-120	423.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	46.64	3.00e-120	422.00
IUUC-Rno-105291	Rattus norvegicus	47.31	7.00e-107	378.00
IUUC-Sce-106204	Saccharomyces cerevisiae	58.35	4.00e-156	541.00
IUUC-Sha-106943	Sarcophilus harrisii	50.00	2.00e-103	367.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	57.45	8.00e-112	395.00
IUUC-Spo-108049	Schizosaccharomyces pombe	51.03	4.00e-115	405.00
IUUC-Smo-109043	Selaginella moellendorffii	50.00	3.00e-99	352.00
IUUC-Sit-110431	Setaria italica	52.12	1.00e-102	364.00
IUUC-Sly-111391	Solanum lycopersicum	52.66	2.00e-99	353.00
IUUC-Stu-112364	Solanum tuberosum	48.68	7.00e-84	301.00
IUUC-Sar-113450	Sorex araneus	48.85	2.00e-105	373.00
IUUC-Sbi-113829	Sorghum bicolor	52.42	2.00e-102	363.00
IUUC-Sre-115153	Sporisorium reilianum	55.08	1.00e-106	378.00
IUUC-Ssc-116274	Sus scrofa	49.43	3.00e-107	380.00
IUUC-Tgu-117417	Taeniopygia guttata	49.71	2.00e-107	380.00
IUUC-Tru-117615	Takifugu rubripes	43.81	2.00e-98	350.00
IUUC-Tsy-119480	Tarsius syrichta	47.31	5.00e-107	379.00
IUUC-Tni-119847	Tetraodon nigroviridis	45.05	1.00e-105	374.00
IUUC-Tca-121287	Theobroma cacao	52.12	1.00e-103	367.00
IUUC-Tre-122010	Trichoderma reesei	54.85	1.00e-117	414.00
IUUC-Tvi-122475	Trichoderma virens	54.55	9.00e-118	414.00
IUUC-Tae-124921	Triticum aestivum	53.33	8.00e-104	368.00
IUUC-Tur-126116	Triticum urartu	44.55	4.00e-76	276.00
IUUC-Tme-126992	Tuber melanosporum	54.60	7.00e-118	415.00
IUUC-Tbe-127803	Tupaia belangeri	49.30	2.00e-84	303.00
IUUC-Ttr-128933	Tursiops truncatus	47.96	9.00e-108	381.00
IUUC-Uma-129447	Ustilago maydis	54.49	3.00e-106	376.00
IUUC-Vda-129780	Verticillium dahliae	54.36	1.00e-118	417.00
IUUC-Vpa-130557	Vicugna pacos	33.99	4.00e-33	133.00
IUUC-Vvi-130918	Vitis vinifera	50.16	2.00e-97	347.00
IUUC-Xtr-132409	Xenopus tropicalis	47.61	3.00e-106	376.00
IUUC-Xma-133420	Xiphophorus maculatus	49.71	1.00e-105	374.00
IUUC-Yli-134362	Yarrowia lipolytica	49.75	1.00e-119	420.00
IUUC-Zma-135804	Zea mays	50.75	8.00e-100	355.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence