iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033831

Ensembl Protein ID

ENSECAP00000014066.1

UniProt Accession

F6XD72; F6XD72_HORSE

Protein Name

Uncharacterized protein

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015360.1	ENSECAT00000017323.1	ENSECAP00000014066.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-15	56.9	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MRAVLTWRDK AEQCIYDLAF KPDGTQLILA AGNRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY THNDSIQCVS YNPVTHQLAS CSSNDFGLWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGGGAAGC GGCTGTCTCT GAGGCGGGTA GGAGGGGTCC GAGGCGTGAG GGAAGTCGCG 60
ATGCGGGCCG TGTTGACGTG GAGAGATAAA GCCGAGCAGT GGTGAGGAGC AGGGCAGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005929--C:cilium
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0060271--P:cilium assembly
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

KEGG

ecb:100050891

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	97.43	0.00e+00	2390.00
IUUC-Apl-003504	Anas platyrhynchos	85.66	0.00e+00	2130.00
IUUC-Aca-004767	Anolis carolinensis	85.73	0.00e+00	2159.00
IUUC-Ame-011642	Astyanax mexicanus	75.80	0.00e+00	1934.00
IUUC-Bta-012969	Bos taurus	94.76	0.00e+00	2316.00
IUUC-Cel-018670	Caenorhabditis elegans	38.60	0.00e+00	897.00
IUUC-Cja-019249	Callithrix jacchus	88.01	0.00e+00	2155.00
IUUC-Cfa-020915	Canis familiaris	97.91	0.00e+00	2356.00
IUUC-Cpo-021888	Cavia porcellus	84.67	0.00e+00	2129.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	49.07	0.00e+00	1133.00
IUUC-Csa-023533	Chlorocebus sabaeus	93.15	0.00e+00	2298.00
IUUC-Cin-025121	Ciona intestinalis	58.70	0.00e+00	1522.00
IUUC-Csv-026240	Ciona savignyi	59.02	0.00e+00	1454.00
IUUC-Dno-029685	Dasypus novemcinctus	91.38	0.00e+00	2242.00
IUUC-Dme-032005	Drosophila melanogaster	24.05	1.00e-07	52.40
IUUC-Ete-032682	Echinops telfairi	86.10	0.00e+00	1714.00
IUUC-Eeu-034919	Erinaceus europaeus	88.04	0.00e+00	1048.00
IUUC-Fca-036559	Felis catus	97.02	0.00e+00	2409.00
IUUC-Fal-037340	Ficedula albicollis	83.70	0.00e+00	2087.00
IUUC-Gga-040595	Gallus gallus	84.54	0.00e+00	2142.00
IUUC-Ggo-045356	Gorilla gorilla	89.07	0.00e+00	2260.00
IUUC-Hsa-046135	Homo sapiens	88.93	0.00e+00	2259.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	83.05	0.00e+00	1997.00
IUUC-Lch-050183	Latimeria chalumnae	82.93	0.00e+00	1188.00
IUUC-Loc-052049	Lepisosteus oculatus	81.51	0.00e+00	2067.00
IUUC-Laf-053728	Loxodonta africana	96.38	0.00e+00	2397.00
IUUC-Mcc-054971	Macaca mulatta	90.10	0.00e+00	2279.00
IUUC-Meu-056446	Macropus eugenii	86.74	0.00e+00	2209.00
IUUC-Mga-059296	Meleagris gallopavo	81.65	0.00e+00	2114.00
IUUC-Mmr-061232	Microcebus murinus	92.62	0.00e+00	2295.00
IUUC-Mdo-062115	Monodelphis domestica	94.52	0.00e+00	2361.00
IUUC-Mmu-063664	Mus musculus	94.52	0.00e+00	2394.00
IUUC-Mpu-066136	Mustela putorius furo	93.57	0.00e+00	2308.00
IUUC-Mlu-068238	Myotis lucifugus	93.00	0.00e+00	2325.00
IUUC-Nle-069003	Nomascus leucogenys	89.22	0.00e+00	2182.00
IUUC-Ont-072080	Oreochromis niloticus	76.54	0.00e+00	1960.00
IUUC-Oan-072891	Ornithorhynchus anatinus	83.00	0.00e+00	914.00
IUUC-Ocu-074262	Oryctolagus cuniculus	93.88	0.00e+00	2303.00
IUUC-Ola-086538	Oryzias latipes	73.34	0.00e+00	1860.00
IUUC-Oga-088722	Otolemur garnettii	91.63	0.00e+00	2253.00
IUUC-Oar-089249	Ovis aries	90.01	0.00e+00	2218.00
IUUC-Ptr-090752	Pan troglodytes	84.83	0.00e+00	2113.00
IUUC-Pan-092472	Papio anubis	93.08	0.00e+00	2295.00
IUUC-Psi-093335	Pelodiscus sinensis	86.47	0.00e+00	2189.00
IUUC-Pma-094520	Petromyzon marinus	70.40	0.00e+00	1486.00
IUUC-Ppa-095600	Physcomitrella patens	61.95	7.00e-40	155.00
IUUC-Pfo-096526	Poecilia formosa	72.80	0.00e+00	1819.00
IUUC-Pab-098428	Pongo abelii	89.92	0.00e+00	1113.00
IUUC-Pca-100233	Procavia capensis	72.33	0.00e+00	979.00
IUUC-Pva-103064	Pteropus vampyrus	84.21	0.00e+00	2047.00
IUUC-Rno-105764	Rattus norvegicus	95.08	0.00e+00	2373.00
IUUC-Sha-106649	Sarcophilus harrisii	94.15	0.00e+00	2331.00
IUUC-Smo-109478	Selaginella moellendorffii	39.54	0.00e+00	738.00
IUUC-Tgu-116870	Taeniopygia guttata	84.01	0.00e+00	2055.00
IUUC-Tru-118661	Takifugu rubripes	71.34	0.00e+00	1811.00
IUUC-Tsy-119640	Tarsius syrichta	77.14	0.00e+00	668.00
IUUC-Tni-120812	Tetraodon nigroviridis	72.55	0.00e+00	1816.00
IUUC-Ttr-128862	Tursiops truncatus	92.64	0.00e+00	2362.00
IUUC-Vpa-130049	Vicugna pacos	88.29	3.00e-156	545.00
IUUC-Xtr-131914	Xenopus tropicalis	79.79	0.00e+00	2020.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence