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Tag Content
UUCD2 ID IUUC-Fca-035861
UUCD1 version UUC-FeC-00760
Ensembl Protein ID ENSFCAP00000003263.3
UniProt Accession M3W0I5; M3W0I5_FELCA
Genbank Protein ID ENSFCAP00000003263
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AANG02055700
Gene Name USP22
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000003536.3 ENSFCAT00000003536.3 ENSFCAP00000003263.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.90e-93 312.7 132 475
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ ++++++ +   +p+ +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 132  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHRCEMQ---SPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQ 216
           9*****************************.99999875...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  ++ ++ +++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 217  DAHEFLIAALDVLHRHCKG----------------DDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGS 289
           *****************22................22335677899999**************************************** PP
   S: 180  eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
           ++   +                    +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++kklP v ++hLkRf  +++ k r+k
   Q: 290  STPFWPlspgsegsvvngeshvagttTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRK 376
           *87777************************************************************************..5666899** PP
   S: 249  inkkvefpleLdlspfcts............peekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevlee 325
           i+++v+fpleLd++pf++s            p+++ ++++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD  +t+ + e+vl  
   Q: 377  ITTYVSFPLELDMTPFMASskesrmngqyqqPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIEDVLD- 464
           *******************5555555555554445555**************************************************. PP
   S: 326  tgstaYvlfYkrr 338
             s++Y+lfY+++
   Q: 465  --SEGYLLFYHKQ 475
           ..********985 PP
   
Organism Felis catus
Protein Sequence
(Fasta)
MRWLLILFSR FQAKSCVCHV CGVHLNRLHS CLHCVFFGCF TKKHIHEHAK SKRHNLAIDL 60
MYGGIYCFLC QDYIYDKDME IIAKEEQRKA WKMQGVGEKF STWEPTKREL ELLKHNPKRR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fca-035861|DUB,USP|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGCCCGTCG TGCCATGCGC TGGCTCCTAA TTCTCTTCTC TCGATTTCAG GCAAAGTCGT 60
GTGTGTGTCA CGTCTGTGGT GTCCACCTGA ACAGGCTCCA CTCCTGCCTG CACTGCGTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fca-035861|DUB,USP|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0732--Signal
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
Gene Ontology

GO:0000124--C:SAGA complex
GO:0010485--F:H4 histone acetyltransferase activity
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:0016574--P:histone ubiquitination
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG fca:101089554
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000393 Aegilops tauschii 38.12 3.00e-65 243.00
IUUC-Aml-001343 Ailuropoda melanoleuca 98.29 0.00e+00 971.00
IUUC-Atr-002653 Amborella trichopoda 39.39 2.00e-96 345.00
IUUC-Apl-003433 Anas platyrhynchos 92.98 0.00e+00 952.00
IUUC-Aca-005347 Anolis carolinensis 89.58 0.00e+00 937.00
IUUC-Ago-007811 Ashbya gossypii 31.57 4.00e-54 205.00
IUUC-Acl-008124 Aspergillus clavatus 31.61 3.00e-58 219.00
IUUC-Afl-008464 Aspergillus flavus 32.77 2.00e-54 206.00
IUUC-Afu-008912 Aspergillus fumigatus 31.16 3.00e-56 212.00
IUUC-Ani-009168 Aspergillus nidulans 32.33 2.00e-58 219.00
IUUC-Ang-009694 Aspergillus niger 31.65 4.00e-56 212.00
IUUC-Aor-010035 Aspergillus oryzae 34.83 3.00e-38 151.00
IUUC-Ate-010382 Aspergillus terreus 32.05 2.00e-52 199.00
IUUC-Ame-011253 Astyanax mexicanus 85.77 0.00e+00 837.00
IUUC-Bgr-012150 Blumeria graminis 30.98 1.00e-48 187.00
IUUC-Bta-013303 Bos taurus 98.51 0.00e+00 972.00
IUUC-Bci-013604 Botrytis cinerea 32.42 4.00e-57 215.00
IUUC-Bdi-014171 Brachypodium distachyon 35.56 4.00e-77 282.00
IUUC-Cja-019283 Callithrix jacchus 99.06 0.00e+00 886.00
IUUC-Cfa-021239 Canis familiaris 99.36 0.00e+00 979.00
IUUC-Cpo-022354 Cavia porcellus 97.65 0.00e+00 965.00
IUUC-Csa-023145 Chlorocebus sabaeus 98.51 0.00e+00 976.00
IUUC-Cho-024938 Choloepus hoffmanni 98.28 1.00e-66 247.00
IUUC-Cin-025109 Ciona intestinalis 57.82 3.00e-122 431.00
IUUC-Csv-026214 Ciona savignyi 56.27 2.00e-169 588.00
IUUC-Cgl-026457 Colletotrichum gloeosporioides 32.31 3.00e-56 212.00
IUUC-Cne-027085 Cryptococcus neoformans 32.82 2.00e-62 233.00
IUUC-Dre-027433 Danio rerio 93.59 0.00e+00 929.00
IUUC-Dno-030095 Dasypus novemcinctus 97.65 0.00e+00 970.00
IUUC-Dor-030481 Dipodomys ordii 97.69 1.00e-100 360.00
IUUC-Dse-031415 Dothistroma septosporum 32.37 1.00e-61 230.00
IUUC-Dme-032074 Drosophila melanogaster 52.95 9.00e-134 470.00
IUUC-Ete-033175 Echinops telfairi 77.28 0.00e+00 630.00
IUUC-Eca-033736 Equus caballus 98.93 0.00e+00 974.00
IUUC-Eeu-034814 Erinaceus europaeus 100.00 8.00e-124 437.00
IUUC-Fal-037645 Ficedula albicollis 93.07 0.00e+00 935.00
IUUC-Fox-038046 Fusarium oxysporum 31.61 4.00e-56 212.00
IUUC-Fso-038321 Fusarium solani 33.11 6.00e-56 211.00
IUUC-Gmo-038474 Gadus morhua 93.92 4.00e-171 594.00
IUUC-Ggr-040044 Gaeumannomyces graminis 32.53 1.00e-57 217.00
IUUC-Gga-040624 Gallus gallus 92.77 0.00e+00 950.00
IUUC-Gac-042197 Gasterosteus aculeatus 87.06 0.00e+00 862.00
IUUC-Gma-042897 Glycine max 33.90 8.00e-82 298.00
IUUC-Ggo-044409 Gorilla gorilla 98.51 0.00e+00 976.00
IUUC-Hsa-046521 Homo sapiens 98.51 0.00e+00 975.00
IUUC-Hvu-047739 Hordeum vulgare 38.67 8.00e-70 257.00
IUUC-Itr-048375 Ictidomys tridecemlineatus 97.87 0.00e+00 967.00
IUUC-Kpa-049135 Komagataella pastoris 35.41 2.00e-70 259.00
IUUC-Lch-050537 Latimeria chalumnae 94.67 0.00e+00 950.00
IUUC-Lpe-050969 Leersia perrieri 38.13 4.00e-73 268.00
IUUC-Loc-052765 Lepisosteus oculatus 83.33 0.00e+00 833.00
IUUC-Lma-053105 Leptosphaeria maculans 34.38 9.00e-66 244.00
IUUC-Laf-053571 Loxodonta africana 98.29 0.00e+00 972.00
IUUC-Mcc-055166 Macaca mulatta 98.51 0.00e+00 976.00
IUUC-Mor-057103 Magnaporthe oryzae 31.85 2.00e-57 216.00
IUUC-Mpo-057621 Magnaporthe poae 32.75 6.00e-57 214.00
IUUC-Mga-059709 Meleagris gallopavo 92.98 0.00e+00 952.00
IUUC-Mvi-060530 Microbotryum violaceum 34.25 1.00e-58 220.00
IUUC-Mmr-060988 Microcebus murinus 98.51 0.00e+00 974.00
IUUC-Mdo-063065 Monodelphis domestica 95.74 0.00e+00 958.00
IUUC-Mmu-063829 Mus musculus 98.08 0.00e+00 971.00
IUUC-Mpu-066687 Mustela putorius furo 98.72 0.00e+00 972.00
IUUC-Nfi-068423 Neosartorya fischeri 31.16 3.00e-56 212.00
IUUC-Ncr-068809 Neurospora crassa 31.03 6.00e-58 218.00
IUUC-Nle-069261 Nomascus leucogenys 94.24 0.00e+00 920.00
IUUC-Opr-070469 Ochotona princeps 80.38 0.00e+00 692.00
IUUC-Ont-071961 Oreochromis niloticus 90.83 0.00e+00 900.00
IUUC-Oan-073565 Ornithorhynchus anatinus 86.16 0.00e+00 919.00
IUUC-Ocu-074435 Oryctolagus cuniculus 98.68 0.00e+00 946.00
IUUC-Oba-075688 Oryza barthii 36.20 2.00e-76 280.00
IUUC-Obr-076652 Oryza brachyantha 41.69 7.00e-75 274.00
IUUC-Ogl-077910 Oryza glaberrima 36.13 6.00e-79 288.00
IUUC-Ogu-078479 Oryza glumaepatula 36.13 5.00e-79 288.00
IUUC-Oin-079697 Oryza indica 39.66 4.00e-76 278.00
IUUC-Olo-080811 Oryza longistaminata 41.38 4.00e-53 201.00
IUUC-Ome-081706 Oryza meridionalis 36.09 9.00e-79 288.00
IUUC-Oni-083070 Oryza nivara 35.73 6.00e-79 288.00
IUUC-Opu-083605 Oryza punctata 40.16 8.00e-68 250.00
IUUC-Oru-084522 Oryza rufipogon 36.13 6.00e-79 288.00
IUUC-Osa-085351 Oryza sativa 39.36 1.00e-76 280.00
IUUC-Ola-086743 Oryzias latipes 88.56 0.00e+00 757.00
IUUC-Olu-087695 Ostreococcus lucimarinus 31.81 2.00e-50 192.00
IUUC-Oga-089131 Otolemur garnettii 94.64 0.00e+00 957.00
IUUC-Oar-089319 Ovis aries 98.72 0.00e+00 972.00
IUUC-Ptr-090783 Pan troglodytes 98.51 0.00e+00 977.00
IUUC-Pan-092927 Papio anubis 98.29 0.00e+00 974.00
IUUC-Psi-093670 Pelodiscus sinensis 92.96 0.00e+00 949.00
IUUC-Pma-094323 Petromyzon marinus 71.82 0.00e+00 724.00
IUUC-Pfo-096462 Poecilia formosa 92.58 0.00e+00 925.00
IUUC-Pab-097612 Pongo abelii 98.72 0.00e+00 976.00
IUUC-Pgr-103657 Puccinia graminis 27.57 7.00e-39 155.00
IUUC-Pte-104340 Pyrenophora teres 33.48 2.00e-59 223.00
IUUC-Pyt-104782 Pyrenophora triticirepentis 35.06 7.00e-67 248.00
IUUC-Rno-105247 Rattus norvegicus 98.08 0.00e+00 971.00
IUUC-Sce-106247 Saccharomyces cerevisiae 31.39 2.00e-52 200.00
IUUC-Sha-107538 Sarcophilus harrisii 95.85 1.00e-124 437.00
IUUC-Sja-107656 Schizosaccharomyces japonicus 34.90 4.00e-67 248.00
IUUC-Spo-108226 Schizosaccharomyces pombe 32.48 7.00e-61 227.00
IUUC-Ssl-108531 Sclerotinia sclerotiorum 31.71 4.00e-54 205.00
IUUC-Sit-109716 Setaria italica 35.83 6.00e-80 291.00
IUUC-Sar-113341 Sorex araneus 86.76 0.00e+00 758.00
IUUC-Sbi-114205 Sorghum bicolor 35.34 5.00e-81 295.00
IUUC-Tgu-116938 Taeniopygia guttata 95.95 0.00e+00 960.00
IUUC-Tru-117622 Takifugu rubripes 89.51 0.00e+00 918.00
IUUC-Tsy-119431 Tarsius syrichta 86.54 0.00e+00 820.00
IUUC-Tni-120661 Tetraodon nigroviridis 92.54 0.00e+00 927.00
IUUC-Tre-122139 Trichoderma reesei 32.41 2.00e-55 209.00
IUUC-Tvi-122599 Trichoderma virens 31.84 3.00e-56 213.00
IUUC-Tae-125608 Triticum aestivum 35.76 9.00e-87 314.00
IUUC-Tme-127115 Tuber melanosporum 38.69 7.00e-82 297.00
IUUC-Ttr-129018 Tursiops truncatus 94.89 0.00e+00 818.00
IUUC-Uma-129455 Ustilago maydis 32.28 1.00e-33 137.00
IUUC-Vda-129829 Verticillium dahliae 32.89 1.00e-35 143.00
IUUC-Xtr-132444 Xenopus tropicalis 91.53 0.00e+00 938.00
IUUC-Xma-133514 Xiphophorus maculatus 92.99 0.00e+00 934.00
IUUC-Yli-134357 Yarrowia lipolytica 30.81 3.00e-48 186.00
IUUC-Zma-134945 Zea mays 35.15 4.00e-77 282.00
Created Date 25-Jun-2017

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