• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
UUCD2 ID IUUC-Cpo-022531
UUCD1 version UUC-CaP-00006
Ensembl Protein ID ENSCPOP00000000109.2
UniProt Accession H0UT81; H0UT81_CAVPO
Genbank Protein ID ENSCPOP00000000109
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAKN02032146
Gene Name SMURF1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000000124.3 ENSCPOT00000000125.2 ENSCPOP00000000109.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.80e-127 425.3 421 756
Active Site
Position(s) Description Evidence
725 Glycyl thioester intermediate {ECO:0000256|PIRSR:PIRSR001569-1,
ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkkrl+v+f+gEegld+gGv+re+l+ll++e+ np++glf+ys ++ ++lq+npds + np+hl++F+f+Gr++g+a+++g++++ 
   Q: 421  PKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSI-NPDHLSYFHFVGRIMGLAVFHGHYING 508
           689*********************************************************9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++ +fyk+llgk+++l+dle+vdpel+ksl +i+en   di+   ld tf+v+++ +g + ++eLkp+G+n+pVt+eNk+eYv+l+v+
   Q: 509  GFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILEN---DITPV-LDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVN 593
           ***********************************99...9***8.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gfne+ip++ll+ F+++elel+i G ++id++d+k++t+ k+ + +ds+ ++wFw+++e f++e r+++LqFv
   Q: 594  WRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKH-CVADSNIVRWFWQAVETFDEERRARLLQFV 681
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk.......prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgs r+Pl+Gf++l+       prlf+i+  da++d+lP+++TCfn++++P+Y+s+e+l+ekLl+A+eet gF +
   Q: 682  TGSTRVPLQGFKALQgstgaagPRLFTIHLiDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAV 756
           ******************************99999**************************************76 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
MSNPGTRRNG SSIKIRLTVL CAKNLAKKDF FRLPDPFAKI VVDGSGQCHS TDTVKNTLDP 60
KWNQHYDLYV GKTDSITISV WNHKKIHKKQ GAGFLGCVRL LSNAISRLKD TGYQRLDLCK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-022531|E3,HECT|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCGAACC CCGGGACGCG CAGGAACGGC TCCAGCATTA AGATCCGCCT GACAGGTACG 60
GCTGGCAGAG GCCCTCTGCC CTCCGGCGCC CCTCGCCCCT CGCCATCTCA TCTCTCCCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-022531|E3,HECT|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom
PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2
Pfam

PF00168--C2
PF00632--HECT
PF00397--WW
SMART

SM00239--C2
SM00119--HECTc
SM00456--WW
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005739--C:mitochondrion
GO:0005886--C:plasma membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0030509--P:BMP signaling pathway
GO:0061736--P:engulfment of target by autophagosome
GO:0030279--P:negative regulation of ossification
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1903861--P:positive regulation of dendrite extension
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006611--P:protein export from nucleus
GO:0034394--P:protein localization to cell surface
GO:0000209--P:protein polyubiquitination
GO:0071211--P:protein targeting to vacuole involved in autophagy
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032801--P:receptor catabolic process
GO:0061753--P:substrate localization to autophagosome
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001459 Ailuropoda melanoleuca 89.45 0.00e+00 1399.00
IUUC-Apl-004155 Anas platyrhynchos 92.74 0.00e+00 1446.00
IUUC-Aca-005238 Anolis carolinensis 91.58 0.00e+00 1417.00
IUUC-Ame-010901 Astyanax mexicanus 87.86 0.00e+00 1375.00
IUUC-Bta-013221 Bos taurus 87.72 0.00e+00 1336.00
IUUC-Cja-018985 Callithrix jacchus 99.08 0.00e+00 1564.00
IUUC-Cfa-020568 Canis familiaris 96.02 0.00e+00 1492.00
IUUC-Csa-024145 Chlorocebus sabaeus 95.38 0.00e+00 1486.00
IUUC-Cho-024963 Choloepus hoffmanni 80.20 0.00e+00 973.00
IUUC-Dre-028341 Danio rerio 88.27 0.00e+00 1386.00
IUUC-Dno-029705 Dasypus novemcinctus 97.20 0.00e+00 1497.00
IUUC-Dme-031740 Drosophila melanogaster 72.28 3.00e-175 608.00
IUUC-Eca-034125 Equus caballus 98.65 0.00e+00 1521.00
IUUC-Fca-035905 Felis catus 94.00 0.00e+00 1439.00
IUUC-Fal-037336 Ficedula albicollis 92.60 0.00e+00 1398.00
IUUC-Gmo-039486 Gadus morhua 76.53 0.00e+00 858.00
IUUC-Gga-040218 Gallus gallus 94.60 0.00e+00 1477.00
IUUC-Gac-041707 Gasterosteus aculeatus 81.96 0.00e+00 1274.00
IUUC-Ggo-045408 Gorilla gorilla 92.42 0.00e+00 1410.00
IUUC-Hsa-045878 Homo sapiens 98.68 0.00e+00 1558.00
IUUC-Itr-048317 Ictidomys tridecemlineatus 97.83 0.00e+00 1504.00
IUUC-Loc-052628 Lepisosteus oculatus 83.05 0.00e+00 1362.00
IUUC-Laf-053644 Loxodonta africana 89.73 0.00e+00 1382.00
IUUC-Mcc-055479 Macaca mulatta 87.85 0.00e+00 1337.00
IUUC-Mga-059723 Meleagris gallopavo 89.43 0.00e+00 1382.00
IUUC-Mdo-063005 Monodelphis domestica 94.32 0.00e+00 1476.00
IUUC-Mmu-063634 Mus musculus 94.98 0.00e+00 1462.00
IUUC-Mpu-065898 Mustela putorius furo 94.49 0.00e+00 1441.00
IUUC-Mlu-067584 Myotis lucifugus 97.45 0.00e+00 1515.00
IUUC-Nle-069033 Nomascus leucogenys 98.65 0.00e+00 1523.00
IUUC-Ont-072265 Oreochromis niloticus 84.36 0.00e+00 1321.00
IUUC-Oan-073621 Ornithorhynchus anatinus 87.94 0.00e+00 1416.00
IUUC-Ocu-073960 Oryctolagus cuniculus 97.17 0.00e+00 1489.00
IUUC-Oga-088579 Otolemur garnettii 98.94 0.00e+00 1562.00
IUUC-Oar-090396 Ovis aries 95.42 0.00e+00 1405.00
IUUC-Ptr-091624 Pan troglodytes 98.68 0.00e+00 1558.00
IUUC-Pan-092479 Papio anubis 98.92 0.00e+00 1525.00
IUUC-Psi-094074 Pelodiscus sinensis 93.31 0.00e+00 1117.00
IUUC-Pfo-097203 Poecilia formosa 81.85 0.00e+00 1281.00
IUUC-Pab-097540 Pongo abelii 98.62 0.00e+00 1488.00
IUUC-Pca-100379 Procavia capensis 73.59 0.00e+00 650.00
IUUC-Rno-105396 Rattus norvegicus 95.11 0.00e+00 1464.00
IUUC-Sha-107216 Sarcophilus harrisii 94.28 0.00e+00 1469.00
IUUC-Sar-113250 Sorex araneus 96.85 0.00e+00 832.00
IUUC-Ssc-116413 Sus scrofa 92.45 0.00e+00 1409.00
IUUC-Tgu-116723 Taeniopygia guttata 93.13 0.00e+00 1411.00
IUUC-Tru-117843 Takifugu rubripes 80.00 0.00e+00 1267.00
IUUC-Tsy-119455 Tarsius syrichta 98.30 0.00e+00 1427.00
IUUC-Tni-120037 Tetraodon nigroviridis 81.23 0.00e+00 1224.00
IUUC-Tbe-127879 Tupaia belangeri 84.55 0.00e+00 1250.00
IUUC-Ttr-128423 Tursiops truncatus 96.88 0.00e+00 1434.00
IUUC-Xtr-132237 Xenopus tropicalis 87.63 0.00e+00 1383.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved