iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028293

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Si:ch211-81i17.1; Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)

Genbank Nucleotide ID

BX569795

Gene Name

tle2; si:ch211-81i17.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000042484.8	ENSDART00000133939.2	ENSDARP00000117865.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-23	81.5	655	693
UBD/Beta-Prp	6.80e-40	138.0	522	692

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t+++WDlr+g++l+
   Q: 655  GHTDGASCIDIsNDgTKLWTGGLDNTVRCWDLREGRQLQ 693
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdls.....tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           ls h + v av++s ++   v ++  + +kvwd+s     +  ++  l   + +++++s+++ p+g +l++G++ +t+ +wdl t +  
   Q: 522  LS-HGEVVCAVTISTSTR-HVYTGGKGCVKVWDISqpgskS--PMAQLDclNRDNYIRSCKLLPDGRTLIVGGEASTLSIWDLATPTPR 606
           43.444788899999985.555555589*******776432..333333559*********************************9987 PP
   S: 130  ee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
            +  l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 607  IKaELTSSAPACYALAISPDNKVCFSCCSDGNIVVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRCWDLREGRQL 692
           765888888888899*********************************9.********************************99754 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MFPQNRPPAP LQPPPGSSAS AAAAAAAAAA ASGSTQPLKL TYPETLDRIK EEFQFLQTQY 60
HSLKLECEKL ATEKTEIQRH YVMYYEMSYG LNIEMHKQTE IAKRLNVICA QLIPFLSQEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAAATGAG TGTAACTTGA GAATTTAACC CTTTGCTTCT TGTTACCACA AGCCAAGCCC 60
TCTCTCTCTC TCTCTCTCTT TTTTTTTTTT TTTGCACGGG GGGGCATGCG TTTCTCTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

dre:565013

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004967	Anolis carolinensis	74.00	0.00e+00	796.00
IUUC-Ame-010668	Astyanax mexicanus	96.00	0.00e+00	1227.00
IUUC-Fal-036893	Ficedula albicollis	73.53	0.00e+00	1031.00
IUUC-Gac-042241	Gasterosteus aculeatus	86.28	0.00e+00	1159.00
IUUC-Loc-052056	Lepisosteus oculatus	80.03	0.00e+00	862.00
IUUC-Ont-071448	Oreochromis niloticus	96.30	0.00e+00	1013.00
IUUC-Ola-086892	Oryzias latipes	94.19	0.00e+00	1009.00
IUUC-Pfo-096291	Poecilia formosa	95.75	0.00e+00	1002.00
IUUC-Tru-118532	Takifugu rubripes	94.24	0.00e+00	991.00
IUUC-Tni-119942	Tetraodon nigroviridis	93.11	0.00e+00	954.00
IUUC-Xtr-132704	Xenopus tropicalis	71.14	0.00e+00	1006.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence