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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Rno-105203
UUCD1 version UUC-RaN-00801
Ensembl Protein ID ENSRNOP00000012317.5
UniProt Accession F7ESD4; F7ESD4_RAT
Genbank Protein ID ENSRNOP00000012317
Protein Name Ring finger protein 126
Genbank Nucleotide ID AABR07073281
Gene Name Rnf126
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000009028.6 ENSRNOT00000012317.6 ENSRNOP00000012317.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 3.50e-09 37.4 231 272
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
    C++C+ed+ ++ ++ lpC+H+fh +C+ w ++++CP+Cr
   Q: 231 CPVCKEDYalgER-VRQLPCNHLFHDSCIVPW------LEQHDSCPVCR 272
    ********99777.******************......**********8 PP
   

Organism Rattus norvegicus
Protein Sequence
(Fasta)
MAEASPQPGR YFCHCCSVEI VPRLPDYICP RCESGFIEEL PEETRNTENG SAPSTAPTDQ 60
NRQPFENVDQ HLFTLPQGYS QFAFGIFDDS FEIPAFPPGA QADDGRDPES RREREHQSRH 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Rno-105203|E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGGGCGGGC GGCGCGGAGG CGGCGGTGGC CATGGCTGAG GCGTCGCCGC AGCCCGGACG 60
GTACTTCTGC CACTGCTGTT CGGTGGAGAT CGTGCCGCGC CTGCCGGTGA GACCCGGACG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Rno-105203|E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0042127--P:regulation of cell proliferation
GO:0042147--P:retrograde transport, endosome to Golgi
GO:0071629--P:ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000551 Aegilops tauschii 45.79 1.00e-24 106.00
IUUC-Aml-002001 Ailuropoda melanoleuca 92.97 9.00e-147 512.00
IUUC-Atr-002522 Amborella trichopoda 49.47 7.00e-27 113.00
IUUC-Apl-003778 Anas platyrhynchos 80.00 2.00e-100 358.00
IUUC-Aca-005166 Anolis carolinensis 78.88 2.00e-110 391.00
IUUC-Aly-006495 Arabidopsis lyrata 28.31 2.00e-21 96.30
IUUC-Ath-007616 Arabidopsis thaliana 31.60 4.00e-29 122.00
IUUC-Acl-008247 Aspergillus clavatus 41.96 1.00e-18 87.80
IUUC-Afl-008423 Aspergillus flavus 42.42 1.00e-17 84.30
IUUC-Afu-008920 Aspergillus fumigatus 44.44 1.00e-17 84.00
IUUC-Ani-009396 Aspergillus nidulans 40.82 2.00e-16 80.10
IUUC-Ang-009638 Aspergillus niger 45.19 2.00e-17 83.20
IUUC-Aor-009896 Aspergillus oryzae 42.00 1.00e-17 84.30
IUUC-Ame-010626 Astyanax mexicanus 72.76 2.00e-117 415.00
IUUC-Bta-012808 Bos taurus 92.10 6.00e-137 479.00
IUUC-Bdi-014137 Brachypodium distachyon 31.00 3.00e-26 112.00
IUUC-Cel-018216 Caenorhabditis elegans 40.79 3.00e-14 72.40
IUUC-Cja-019575 Callithrix jacchus 88.57 9.00e-134 469.00
IUUC-Cfa-020142 Canis familiaris 92.88 6.00e-130 456.00
IUUC-Cpo-022451 Cavia porcellus 92.23 9.00e-140 489.00
IUUC-Csa-023433 Chlorocebus sabaeus 92.63 7.00e-162 562.00
IUUC-Cgl-026759 Colletotrichum gloeosporioides 36.36 2.00e-16 80.90
IUUC-Cne-026837 Cryptococcus neoformans 39.76 2.00e-15 77.40
IUUC-Cme-027122 Cyanidioschyzon merolae 56.00 4.00e-14 73.60
IUUC-Dre-027400 Danio rerio 73.89 3.00e-119 421.00
IUUC-Dno-029349 Dasypus novemcinctus 91.16 6.00e-108 383.00
IUUC-Dor-030103 Dipodomys ordii 94.06 2.00e-122 431.00
IUUC-Eca-034240 Equus caballus 91.19 6.00e-104 369.00
IUUC-Fal-037027 Ficedula albicollis 81.85 9.00e-107 379.00
IUUC-Fox-037736 Fusarium oxysporum 37.08 1.00e-13 70.90
IUUC-Fso-038447 Fusarium solani 36.46 2.00e-15 77.40
IUUC-Gmo-039694 Gadus morhua 72.58 1.00e-126 446.00
IUUC-Ggr-039947 Gaeumannomyces graminis 33.33 1.00e-11 65.10
IUUC-Gga-040682 Gallus gallus 84.59 6.00e-129 453.00
IUUC-Gac-041364 Gasterosteus aculeatus 69.42 4.00e-114 404.00
IUUC-Gma-044015 Glycine max 33.94 6.00e-31 128.00
IUUC-Ggo-045421 Gorilla gorilla 91.11 2.00e-134 471.00
IUUC-Hsa-046723 Homo sapiens 93.79 1.00e-151 528.00
IUUC-Hvu-047602 Hordeum vulgare 29.58 2.00e-24 106.00
IUUC-Itr-048435 Ictidomys tridecemlineatus 94.76 2.00e-127 448.00
IUUC-Lch-050071 Latimeria chalumnae 82.75 3.00e-130 457.00
IUUC-Lpe-051427 Leersia perrieri 48.18 2.00e-26 112.00
IUUC-Loc-052470 Lepisosteus oculatus 64.54 3.00e-95 341.00
IUUC-Lma-053066 Leptosphaeria maculans 43.00 9.00e-21 95.10
IUUC-Laf-054249 Loxodonta africana 69.62 4.00e-69 254.00
IUUC-Mcc-055739 Macaca mulatta 93.61 4.00e-154 536.00
IUUC-Mor-057098 Magnaporthe oryzae 34.72 3.00e-12 67.00
IUUC-Mpo-057470 Magnaporthe poae 32.54 3.00e-12 67.00
IUUC-Mtr-057697 Medicago truncatula 26.20 1.00e-24 106.00
IUUC-Mga-059349 Meleagris gallopavo 80.48 6.00e-116 410.00
IUUC-Mvi-060434 Microbotryum violaceum 37.88 7.00e-20 91.70
IUUC-Mmr-060653 Microcebus murinus 94.25 1.00e-156 545.00
IUUC-Mdo-062442 Monodelphis domestica 89.04 2.00e-148 518.00
IUUC-Mmu-064148 Mus musculus 98.97 6.00e-153 533.00
IUUC-Mac-065133 Musa acuminata 30.26 3.00e-27 115.00
IUUC-Mpu-065917 Mustela putorius furo 89.74 1.00e-131 462.00
IUUC-Mlu-067495 Myotis lucifugus 93.49 1.00e-146 512.00
IUUC-Nfi-068352 Neosartorya fischeri 44.44 9.00e-18 84.70
IUUC-Nle-069274 Nomascus leucogenys 93.79 1.00e-142 498.00
IUUC-Opr-070359 Ochotona princeps 83.61 2.00e-91 328.00
IUUC-Ont-071505 Oreochromis niloticus 74.91 2.00e-121 428.00
IUUC-Oan-073225 Ornithorhynchus anatinus 82.26 1.00e-117 415.00
IUUC-Oba-075047 Oryza barthii 49.09 6.00e-27 114.00
IUUC-Obr-076829 Oryza brachyantha 50.91 1.00e-27 116.00
IUUC-Ogl-077378 Oryza glaberrima 49.09 7.00e-27 114.00
IUUC-Ogu-078709 Oryza glumaepatula 49.09 6.00e-27 114.00
IUUC-Oin-079400 Oryza indica 48.35 9.00e-23 100.00
IUUC-Olo-080762 Oryza longistaminata 49.09 6.00e-27 114.00
IUUC-Ome-081151 Oryza meridionalis 50.51 1.00e-23 103.00
IUUC-Oni-083090 Oryza nivara 49.09 6.00e-27 114.00
IUUC-Opu-083898 Oryza punctata 50.96 1.00e-26 113.00
IUUC-Oru-084267 Oryza rufipogon 49.09 6.00e-27 114.00
IUUC-Osa-086229 Oryza sativa 49.09 6.00e-27 114.00
IUUC-Ola-086315 Oryzias latipes 69.06 1.00e-116 412.00
IUUC-Oga-088067 Otolemur garnettii 94.14 1.00e-141 495.00
IUUC-Ptr-091404 Pan troglodytes 92.89 9.00e-112 395.00
IUUC-Pan-092424 Papio anubis 90.65 3.00e-152 530.00
IUUC-Psi-093171 Pelodiscus sinensis 84.76 4.00e-118 417.00
IUUC-Pma-094408 Petromyzon marinus 44.96 6.00e-63 234.00
IUUC-Ppa-095873 Physcomitrella patens 41.67 7.00e-25 108.00
IUUC-Pfo-097402 Poecilia formosa 69.62 4.00e-119 420.00
IUUC-Pab-097834 Pongo abelii 90.71 5.00e-108 383.00
IUUC-Pop-098993 Populus trichocarpa 31.62 9.00e-24 103.00
IUUC-Pca-100442 Procavia capensis 92.83 7.00e-102 363.00
IUUC-Ppe-101324 Prunus persica 48.62 2.00e-25 109.00
IUUC-Pva-103240 Pteropus vampyrus 92.33 4.00e-158 550.00
IUUC-Pgr-103273 Puccinia graminis 37.50 3.00e-17 82.80
IUUC-Ptt-103768 Puccinia triticina 39.22 3.00e-15 77.00
IUUC-Pte-104223 Pyrenophora teres 40.98 4.00e-21 96.70
IUUC-Pyt-104653 Pyrenophora triticirepentis 40.16 3.00e-21 96.30
IUUC-Sha-107638 Sarcophilus harrisii 87.27 1.00e-133 469.00
IUUC-Ssl-108600 Sclerotinia sclerotiorum 31.75 2.00e-12 67.40
IUUC-Smo-109651 Selaginella moellendorffii 51.69 2.00e-23 100.00
IUUC-Sit-110648 Setaria italica 52.25 6.00e-29 121.00
IUUC-Sly-111407 Solanum lycopersicum 28.81 1.00e-26 113.00
IUUC-Stu-112467 Solanum tuberosum 31.18 1.00e-26 113.00
IUUC-Sbi-114297 Sorghum bicolor 50.45 7.00e-28 117.00
IUUC-Tgu-117502 Taeniopygia guttata 83.56 5.00e-124 437.00
IUUC-Tru-117681 Takifugu rubripes 69.28 8.00e-116 409.00
IUUC-Tni-120092 Tetraodon nigroviridis 67.25 5.00e-112 397.00
IUUC-Tca-121480 Theobroma cacao 47.12 1.00e-25 110.00
IUUC-Tae-124679 Triticum aestivum 45.79 2.00e-24 106.00
IUUC-Tur-126792 Triticum urartu 54.46 3.00e-22 99.00
IUUC-Ttr-128843 Tursiops truncatus 93.10 9.00e-145 506.00
IUUC-Vda-129671 Verticillium dahliae 32.14 5.00e-15 76.30
IUUC-Vvi-131691 Vitis vinifera 31.32 4.00e-27 115.00
IUUC-Xtr-132815 Xenopus tropicalis 57.44 1.00e-95 342.00
IUUC-Xma-133481 Xiphophorus maculatus 69.30 1.00e-118 419.00
IUUC-Zma-135326 Zea mays 50.93 3.00e-26 112.00
Created Date 25-Jun-2017

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