iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004961

UUCD1 version

UUC-AnC-00414

Ensembl Protein ID

ENSACAP00000009601.3

UniProt Accession

H9GFM0; H9GFM0_ANOCA

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009803.3	ENSACAT00000009798.3	ENSACAP00000009601.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.10e-81	273.4	88	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 3    kkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkde 91
            ++ eelf+rYkd++ed+i++eg+e+fc+dl+vdp++++vLvlawk++aat+c+f+r ef++g++a+++dsi+++++++++l +++k+e
   Q: 88   LHRTEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFKVLVLAWKFQAATMCKFTRTEFFEGCKAINADSIDGICARFPSLLNDAKQE 176
           6789************************************************************************************* PP
   S: 92   qkfkdiYrfafnfakd..kgqksldldtaialwkLllaerefklldawlkfLeee..kkksiskDtWnllLefskviakdlsnYdeega 176
           +kfkd+Yrf+f+f++d  +gq+sl++++aialw+L+++++++++ld+wl+fL+e+  ++k+is+DtWn++L+f++vi +dlsnY+e++a
   Q: 177  DKFKDLYRFTFQFGLDseEGQRSLHREIAIALWRLVFTQNKPPILDQWLHFLNENpsGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEA 265
           **************998899**********************************9889******************************* PP
   S: 177  WPvliDefveylk 189
           WP+l+D+fve+++
   Q: 266  WPSLFDTFVEWEM 278
           ***********85 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MGQCVTKCKN PSSTLGSKNG DRESSSKTHG KRSTIHKEEH STGSGKSSGD ILVNGTKKME 60
AAVESSQLPS SSGDSKKEPV SGTEESSLHR TEELFRRYKD EREDAILEEG MERFCNDLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCTGAATT GCGTGAATAC TCAGCTGATC TGCAAAGGAC TAGATCTAAA CCAAGGAGCT 60
TATGGTCTGT GTGTTGACTG AGGGAGAAAA AGCATCTTTG GGACAGCCTG TCAAAACACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005737--C:cytoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0030308--P:negative regulation of cell growth
GO:0043065--P:positive regulation of apoptotic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
GO:0010332--P:response to gamma radiation
GO:0009314--P:response to radiation
GO:0010225--P:response to UV-C

KEGG

acs:100563947

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001689	Ailuropoda melanoleuca	85.14	2.00e-142	498.00
IUUC-Apl-003497	Anas platyrhynchos	85.91	6.00e-148	516.00
IUUC-Aor-009902	Aspergillus oryzae	33.83	6.00e-12	62.80
IUUC-Ame-011413	Astyanax mexicanus	66.67	2.00e-104	371.00
IUUC-Bta-013338	Bos taurus	85.87	1.00e-143	501.00
IUUC-Cja-019458	Callithrix jacchus	84.42	1.00e-140	492.00
IUUC-Cfa-020160	Canis familiaris	85.51	4.00e-143	499.00
IUUC-Cpo-021835	Cavia porcellus	84.53	8.00e-134	469.00
IUUC-Csa-023328	Chlorocebus sabaeus	84.42	4.00e-141	493.00
IUUC-Cho-024888	Choloepus hoffmanni	84.89	4.00e-143	500.00
IUUC-Cin-025134	Ciona intestinalis	53.96	9.00e-62	230.00
IUUC-Csv-025904	Ciona savignyi	52.85	8.00e-34	135.00
IUUC-Dre-027780	Danio rerio	65.11	1.00e-97	349.00
IUUC-Dno-028866	Dasypus novemcinctus	84.42	3.00e-140	490.00
IUUC-Dor-030387	Dipodomys ordii	84.67	8.00e-140	489.00
IUUC-Dme-032081	Drosophila melanogaster	43.24	5.00e-49	187.00
IUUC-Eca-033857	Equus caballus	85.14	5.00e-143	499.00
IUUC-Eeu-034825	Erinaceus europaeus	78.06	2.00e-126	444.00
IUUC-Fca-036130	Felis catus	84.78	4.00e-142	496.00
IUUC-Fal-037296	Ficedula albicollis	84.90	7.00e-147	512.00
IUUC-Gmo-039626	Gadus morhua	66.19	9.00e-98	349.00
IUUC-Ggr-039959	Gaeumannomyces graminis	27.35	1.00e-15	78.20
IUUC-Gga-040741	Gallus gallus	85.62	4.00e-144	503.00
IUUC-Gac-042271	Gasterosteus aculeatus	66.55	1.00e-96	345.00
IUUC-Ggo-044727	Gorilla gorilla	84.42	4.00e-141	493.00
IUUC-Hsa-046288	Homo sapiens	84.78	2.00e-141	494.00
IUUC-Itr-049054	Ictidomys tridecemlineatus	80.92	6.00e-147	513.00
IUUC-Lch-050289	Latimeria chalumnae	79.02	2.00e-132	464.00
IUUC-Loc-052455	Lepisosteus oculatus	71.58	3.00e-110	390.00
IUUC-Laf-054369	Loxodonta africana	84.78	9.00e-137	479.00
IUUC-Mcc-055413	Macaca mulatta	67.63	6.00e-98	350.00
IUUC-Meu-056535	Macropus eugenii	83.56	1.00e-145	508.00
IUUC-Mga-059290	Meleagris gallopavo	85.23	3.00e-147	513.00
IUUC-Mmr-060689	Microcebus murinus	84.78	2.00e-141	494.00
IUUC-Mdo-062128	Monodelphis domestica	85.87	2.00e-139	487.00
IUUC-Mmu-064396	Mus musculus	79.28	9.00e-145	505.00
IUUC-Mpu-065926	Mustela putorius furo	85.14	2.00e-142	498.00
IUUC-Mlu-067044	Myotis lucifugus	84.56	2.00e-147	514.00
IUUC-Nle-069346	Nomascus leucogenys	84.42	4.00e-141	493.00
IUUC-Opr-070682	Ochotona princeps	85.14	2.00e-133	468.00
IUUC-Ont-071772	Oreochromis niloticus	69.89	3.00e-104	371.00
IUUC-Oan-072765	Ornithorhynchus anatinus	85.04	2.00e-141	494.00
IUUC-Ocu-074272	Oryctolagus cuniculus	92.55	5.00e-106	376.00
IUUC-Ola-087561	Oryzias latipes	69.79	2.00e-106	378.00
IUUC-Oga-088440	Otolemur garnettii	68.25	3.00e-108	384.00
IUUC-Oar-089403	Ovis aries	85.87	5.00e-144	503.00
IUUC-Ptr-091384	Pan troglodytes	84.42	4.00e-141	493.00
IUUC-Pan-092650	Papio anubis	84.42	4.00e-141	493.00
IUUC-Psi-093806	Pelodiscus sinensis	86.58	8.00e-140	489.00
IUUC-Pma-094196	Petromyzon marinus	61.41	2.00e-86	311.00
IUUC-Pfo-096584	Poecilia formosa	69.29	4.00e-107	380.00
IUUC-Pab-098605	Pongo abelii	84.42	4.00e-141	493.00
IUUC-Pca-100933	Procavia capensis	68.25	5.00e-98	350.00
IUUC-Pva-102172	Pteropus vampyrus	83.15	4.00e-141	493.00
IUUC-Rno-105406	Rattus norvegicus	79.93	1.00e-145	508.00
IUUC-Sha-106531	Sarcophilus harrisii	83.22	7.00e-145	506.00
IUUC-Sar-113051	Sorex araneus	67.52	2.00e-98	352.00
IUUC-Ssc-115555	Sus scrofa	84.78	4.00e-142	496.00
IUUC-Tgu-117178	Taeniopygia guttata	85.71	7.00e-149	519.00
IUUC-Tru-117876	Takifugu rubripes	69.72	3.00e-106	377.00
IUUC-Tsy-118790	Tarsius syrichta	83.12	1.00e-118	419.00
IUUC-Tni-119673	Tetraodon nigroviridis	69.61	6.00e-106	376.00
IUUC-Tbe-127429	Tupaia belangeri	84.42	4.00e-141	493.00
IUUC-Ttr-128467	Tursiops truncatus	85.51	3.00e-143	500.00
IUUC-Vpa-130376	Vicugna pacos	58.55	3.00e-82	297.00
IUUC-Xtr-132134	Xenopus tropicalis	80.41	1.00e-126	445.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence