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Tag Content
iUUCD ID IUUC-Oga-088336
Ensembl Protein ID ENSOGAP00000014951.2
UniProt Accession H0XFY1; H0XFY1_OTOGA
Genbank Protein ID ENSOGAP00000014951
Protein Name Inhibitor of growth protein
Genbank Nucleotide ID AAQR03095272
Gene Name ING2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000016707.2 ENSOGAT00000016710.2 ENSOGAP00000014951.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 3.60e-09 36.7 220 266
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
    ++C +C + + +e ++ C++ C ewfH+ C++l+ +p+ + w+CpkCr
   Q: 220 TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 266
    69*.*******99..*****999*99***********...888886.******8 PP
   

Organism Otolemur garnettii
Protein Sequence
(Fasta)
SGGRMLGQQQ QQQQQLYSSA ALLTGERSRL LTCYVQDYLE CVESLPHDMQ RNVSVLRELD 60
NKYQETLKEI DDVYEKYKKE DDLNQKKRLQ QLLQRALINS QELGDEKIQI VTQMLELVEN 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Oga-088336|E3,PHD|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCGGCGGCA GGATGTTAGG GCAGCAGCAG CAGCAGCAGC AGCAGCTGTA CTCGTCAGCC 60
GCGCTCCTGA CCGGGGAGCG GAGCCGGCTG CTCACCTGCT ACGTGCAGGA CTACCTCGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Oga-088336|E3,PHD|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002213 Ailuropoda melanoleuca 97.79 2.00e-118 417.00
IUUC-Apl-003705 Anas platyrhynchos 88.79 1.00e-90 325.00
IUUC-Aca-004990 Anolis carolinensis 81.47 1.00e-97 349.00
IUUC-Ame-011426 Astyanax mexicanus 71.17 9.00e-84 303.00
IUUC-Bta-012721 Bos taurus 98.23 6.00e-120 423.00
IUUC-Cja-018960 Callithrix jacchus 99.24 1.00e-107 382.00
IUUC-Cfa-020869 Canis familiaris 96.49 7.00e-119 419.00
IUUC-Cpo-021414 Cavia porcellus 95.96 5.00e-116 410.00
IUUC-Csa-023304 Chlorocebus sabaeus 99.26 3.00e-112 397.00
IUUC-Dre-028562 Danio rerio 68.63 3.00e-88 318.00
IUUC-Dno-029945 Dasypus novemcinctus 97.73 3.00e-114 404.00
IUUC-Dor-030141 Dipodomys ordii 96.32 4.00e-115 407.00
IUUC-Ete-032709 Echinops telfairi 96.82 8.00e-129 452.00
IUUC-Eca-033432 Equus caballus 98.53 9.00e-119 419.00
IUUC-Eeu-035285 Erinaceus europaeus 99.02 2.00e-90 324.00
IUUC-Fca-036467 Felis catus 98.11 5.00e-114 403.00
IUUC-Fal-036700 Ficedula albicollis 87.56 6.00e-90 323.00
IUUC-Gmo-038748 Gadus morhua 63.04 8.00e-85 306.00
IUUC-Gga-040175 Gallus gallus 88.34 1.00e-90 325.00
IUUC-Gac-041403 Gasterosteus aculeatus 64.23 2.00e-89 321.00
IUUC-Hsa-045837 Homo sapiens 99.26 3.00e-112 397.00
IUUC-Itr-049062 Ictidomys tridecemlineatus 97.79 4.00e-118 417.00
IUUC-Lch-049965 Latimeria chalumnae 80.92 3.00e-99 354.00
IUUC-Laf-053353 Loxodonta africana 96.89 2.00e-100 357.00
IUUC-Mcc-055155 Macaca mulatta 98.85 3.00e-73 266.00
IUUC-Meu-056470 Macropus eugenii 93.31 1.00e-110 392.00
IUUC-Mga-059570 Meleagris gallopavo 88.34 6.00e-90 323.00
IUUC-Mmr-061385 Microcebus murinus 99.63 1.00e-112 399.00
IUUC-Mdo-062144 Monodelphis domestica 93.36 5.00e-112 397.00
IUUC-Mmu-063215 Mus musculus 96.69 1.00e-117 415.00
IUUC-Mpu-065749 Mustela putorius furo 97.07 8.00e-98 349.00
IUUC-Mlu-067245 Myotis lucifugus 75.00 1.00e-80 291.00
IUUC-Nle-069968 Nomascus leucogenys 98.42 6.00e-82 296.00
IUUC-Ont-071524 Oreochromis niloticus 65.93 3.00e-86 311.00
IUUC-Ocu-074870 Oryctolagus cuniculus 98.59 3.00e-120 424.00
IUUC-Oar-090136 Ovis aries 97.17 6.00e-118 416.00
IUUC-Ptr-091348 Pan troglodytes 98.95 1.00e-82 299.00
IUUC-Pan-092819 Papio anubis 99.26 3.00e-112 397.00
IUUC-Psi-093854 Pelodiscus sinensis 86.21 1.00e-62 231.00
IUUC-Pfo-096633 Poecilia formosa 66.67 4.00e-80 290.00
IUUC-Pab-098346 Pongo abelii 98.90 8.00e-112 396.00
IUUC-Pca-100278 Procavia capensis 95.67 2.00e-116 411.00
IUUC-Pva-103190 Pteropus vampyrus 98.86 4.00e-115 407.00
IUUC-Rno-104940 Rattus norvegicus 96.59 1.00e-112 398.00
IUUC-Sha-107533 Sarcophilus harrisii 91.54 5.00e-113 400.00
IUUC-Sar-113630 Sorex araneus 96.08 1.00e-88 318.00
IUUC-Ssc-115734 Sus scrofa 98.86 4.00e-115 407.00
IUUC-Tgu-117034 Taeniopygia guttata 88.00 2.00e-90 324.00
IUUC-Tru-118168 Takifugu rubripes 61.68 3.00e-81 294.00
IUUC-Tsy-119494 Tarsius syrichta 99.51 4.00e-83 300.00
IUUC-Tni-120100 Tetraodon nigroviridis 62.35 1.00e-76 279.00
IUUC-Ttr-128442 Tursiops truncatus 98.53 8.00e-90 322.00
IUUC-Vpa-130063 Vicugna pacos 97.43 8.00e-118 416.00
Created Date 25-Jun-2017

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