iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066816

Ensembl Protein ID

ENSMPUP00000018732.1

UniProt Accession

M3Z570; M3Z570_MUSPF

Genbank Protein ID

ENSMPUP00000018732

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01006745

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000018852.1	ENSMPUT00000019004.1	ENSMPUP00000018732.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.26	9.00e-157	550.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

RMAGCGEIDH SINMLPTNRK ANESCANTAP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

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Nucleotide Sequence
(Fasta)

AGGATGGCTG GCTGTGGTGA AATTGATCAC TCAATAAACA TGCTTCCTAC GAACAGGAAA 60
GCGAATGAGT CCTGTGCGAA TACTGCACCT TCTCTAACTG TCCCTGAATG TGCCATTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	96.67	3.00e-152	531.00
IUUC-Apl-004143	Anas platyrhynchos	85.32	4.00e-135	474.00
IUUC-Aca-004557	Anolis carolinensis	80.06	9.00e-130	456.00
IUUC-Ame-011088	Astyanax mexicanus	61.24	2.00e-83	302.00
IUUC-Bta-012639	Bos taurus	92.74	2.00e-150	525.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	5.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	95.26	1.00e-153	535.00
IUUC-Cfa-021140	Canis familiaris	92.20	2.00e-159	554.00
IUUC-Cpo-021387	Cavia porcellus	89.17	3.00e-158	551.00
IUUC-Csa-023503	Chlorocebus sabaeus	91.67	1.00e-147	515.00
IUUC-Cho-024895	Choloepus hoffmanni	89.84	1.00e-133	468.00
IUUC-Cin-025455	Ciona intestinalis	52.56	2.00e-43	168.00
IUUC-Dre-028824	Danio rerio	47.16	3.00e-83	301.00
IUUC-Dno-029269	Dasypus novemcinctus	92.80	8.00e-153	533.00
IUUC-Dor-030592	Dipodomys ordii	90.53	9.00e-155	539.00
IUUC-Dme-031618	Drosophila melanogaster	58.00	5.00e-56	211.00
IUUC-Ete-032478	Echinops telfairi	90.83	6.00e-154	536.00
IUUC-Eca-033389	Equus caballus	95.26	9.00e-171	592.00
IUUC-Fca-035488	Felis catus	95.83	2.00e-156	545.00
IUUC-Fal-037087	Ficedula albicollis	83.66	4.00e-147	513.00
IUUC-Gga-040401	Gallus gallus	85.56	5.00e-138	483.00
IUUC-Gac-042412	Gasterosteus aculeatus	64.29	8.00e-88	317.00
IUUC-Ggo-045417	Gorilla gorilla	95.65	1.00e-146	512.00
IUUC-Hsa-045790	Homo sapiens	94.99	5.00e-153	533.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	91.94	7.00e-157	546.00
IUUC-Lch-049493	Latimeria chalumnae	69.72	2.00e-112	398.00
IUUC-Loc-052927	Lepisosteus oculatus	69.35	6.00e-99	353.00
IUUC-Laf-053904	Loxodonta africana	93.07	3.00e-153	534.00
IUUC-Mcc-055427	Macaca mulatta	90.83	6.00e-153	533.00
IUUC-Mmr-060580	Microcebus murinus	93.07	4.00e-148	517.00
IUUC-Mdo-062094	Monodelphis domestica	96.18	2.00e-77	280.00
IUUC-Mmu-063363	Mus musculus	89.69	2.00e-154	538.00
IUUC-Mlu-067433	Myotis lucifugus	95.29	2.00e-172	598.00
IUUC-Nle-068986	Nomascus leucogenys	94.15	2.00e-165	574.00
IUUC-Ont-072670	Oreochromis niloticus	65.22	3.00e-81	295.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.56	2.00e-107	380.00
IUUC-Ocu-074161	Oryctolagus cuniculus	91.06	2.00e-154	538.00
IUUC-Ola-086902	Oryzias latipes	59.42	2.00e-84	305.00
IUUC-Oga-089159	Otolemur garnettii	92.18	1.00e-172	598.00
IUUC-Oar-089586	Ovis aries	93.31	6.00e-144	503.00
IUUC-Ptr-090987	Pan troglodytes	94.99	5.00e-153	533.00
IUUC-Pan-091867	Papio anubis	90.86	2.00e-153	535.00
IUUC-Psi-094024	Pelodiscus sinensis	84.21	4.00e-141	494.00
IUUC-Pma-094453	Petromyzon marinus	63.91	5.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	50.78	1.00e-84	306.00
IUUC-Pab-097997	Pongo abelii	93.87	4.00e-158	550.00
IUUC-Pca-100260	Procavia capensis	91.64	5.00e-161	560.00
IUUC-Pva-103140	Pteropus vampyrus	93.61	2.00e-155	541.00
IUUC-Rno-105795	Rattus norvegicus	84.08	8.00e-152	529.00
IUUC-Sha-107033	Sarcophilus harrisii	87.53	3.00e-148	517.00
IUUC-Ssc-116395	Sus scrofa	95.29	2.00e-170	591.00
IUUC-Tgu-116685	Taeniopygia guttata	83.10	2.00e-136	478.00
IUUC-Tru-118014	Takifugu rubripes	74.40	4.00e-84	304.00
IUUC-Tsy-119326	Tarsius syrichta	86.91	5.00e-162	563.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.95	2.00e-82	298.00
IUUC-Tbe-128067	Tupaia belangeri	93.06	3.00e-159	554.00
IUUC-Ttr-128530	Tursiops truncatus	95.28	3.00e-156	544.00
IUUC-Vpa-130322	Vicugna pacos	96.10	8.00e-161	559.00
IUUC-Xtr-132606	Xenopus tropicalis	68.25	9.00e-120	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence